The study was carried out on 58 premature newborn underweight babies at the Department of Rehabilitation of Pediatric Hospital, HCM City from Jan 1999 to May 2002. The babies have been monitored from the first 12th hour after birth to the discharge day of hospital. Results showed that premature newly born underweigh babies with disturbance of oxygene metabolism and acidosis blood metabolism had got the higher fatal versus the omes who had not. The ealier correcting of these disturbances will help to improve the mortality. It should increase the early use of surfactants at the Department of neonatal rehabilitation to reduce the risks of internal membranous disorders.
Mortality ; Risk factors ; Infant, Low Birth Weight ; Premature Birth ; Infant, Premature

The study conducted on 58 premature neonate underweight infants at the Department of Resuscitation of the Pediatric Hospital N02 from Febuary 2000 to December 2002 had showed a high mortality of 74.1%. 100% of premature neonate underweight infants under 850g at birth died. The died infant had lower weight at birth, mean arterial blood pH was lower, mean arterial blood PaCO2 was higher. CRIB score had prognostic value to predict the mortality of premature neonate underweight infants using ROC curb and the undercurb superficial zone
Aging, Premature ; Infant Equipment ; Child

Chitin is a natural product while chitosan is synthetic product from chitin. A study on the activity of chitin and chitosan in dogs has shown that the use of intradermal chitosan at dose of 200 mg/kg killed all experimental dogs because of pulmonary hemorrhage while this dose of chitin did not kill any dogs. Until now, it was limited to use chitin and chitosan in human as a food complementary, anti obesity and scar healing.
chotosan ; chitin ; toxicity

Background: The effect of air pollution on human health has been paying attentions by researchers in recent years. Exposing air pollutants increases risk for respiratory tract and heart diseases. Objective: 1. To evaluate the situation of air pollution in Thuong Dinh industrial zone and Lac Long Quan area. 2. To compare the respiratory tract morbidity rate which is asscociated with air pollution in residents living in these two areas. Subjects and method: A cross-sectional, comparative study on air pollution indicators and respiratory tract morbidity rate was conducted in 3.963 residents living in Lac Long Quan area and the surroundings of Thuong Dinh industrial zone. Results and Conclusion: The dust pollution rate in Thuong Dinh was as 3-3.5 times high as in Lac Long Quan. Both areas had microorganic pollution. The average concentrations of Pb, As, NO2, Co, SO2, O3 in two seasons were lower than permitted standards, but these concentrations in Thuong Dinh were higher than in Lac Long Quan. There is a significant difference in some respiratory diseases between these two areas. People living in Thuong Dinh industrial zone had a double risk of getting some chronic respiratory diseasess in comparison with those in Lac Long Quan: Rhinitis (OR=1.65; CI95%: 1.3-2.04), bronchitis (OR=1.39; CI95%: 1.04-1.85), amygdalitis (OR=2.14; CI95%: 1.18-3.91), pneumonia (OR=2.53; CI95%: 1.31-4.96). Symptoms of COPD of people in Thuong Dinh were also higher than that in Lac Long Quan: cough (OR=1.87; CI95%: 1.64-3.91); sputum (OR=1.63; CI95%: 1.23-2.17); stuff-up nose (\ufffd?1.3; CI95%: 1.11-1.56); and runny nose (OR=1.91; CI95%: 1.58-2.32).
Respiratory Tract Diseases/ epidemiology ; diagnosis ; Air Pollution/ adverse effects ; prevention & ; control ;

Across descriptive sectional study on 489 workers and pharmacists in the pharmaceutical factories No1 and No2 in Hµ Néi from July to August 1997 has shown that the rate of drug allergy in workers and pharmacists was very high (33.9%). The occupational factors influenced significant on the allergy to Beta-lactamin. The rate of drug allergy was direct proportional with ages and exposure duration. In addition to, the family factors also influenced the drug allergy.
Drug Hypersensitivity ; manpower ; Pharmaceutical Preparations

The study was carried out on 490 workers from 3 pharmaceutical enterprises, and 589 hospital staffs (nurses, pharmacist) from hospitals in Hanoi. Results shown that the prevalence of allergy to beta-lactam antibiotics in pharmaceutical workers and hospital staffs is very high and clearly affected by occupational factors. This issue requires the functioning agencies having solutions of early detection, management and prevention for labor force working in pharmaceutical and health branch.
Hypersensitivity ; Anti-Bacterial Agents ; epidemiology

Study to determine concentration of total serum IgE of 43 health staff with allergy with beta-lactam antibiotics, who are working at hospitals in Hanoi, and control group include 42 healthy persons without any allergic disease or allergic history. Result showed that the average concentration of total serum IgE in the group of health staffs with allergic history to beta-lactam antibiotics is high (X=1968.860 ng/ml). It is higher than 8 times comparing with the group of healthy persons (242.310 ng/ml).
Anti-Bacterial Agents ; Hypersensitivity ; serum ; Medical Staff

Study on 589 nurses and midwives who have been working at least 2 years at hospitals in Hanoi, they were interviewed about the time of occupational contact to antibiotics, the allergic history with beta-lactam antibiotics. All participants were done skin prick test with benzyl penicillin G and ampicillin. Total serum IgE and reaction of mastocyte transform in the subjects who had allergic history to beta-lactam antibiotic. Results showed that the allergic prevalence to beta-lactam antibiotics is very high (9.3%). The occupational factors have clearly affected to the allergy including proportion of occupation ages, family allergic history, and persons who used to suffer from the diseases of allergy and immunology have the allergic risk to beta-lactam antibiotics.
Drug Resistance ; manpower ; Anti-Bacterial Agents ; medical staff

A survey was conducted at 5 hospitals in Hanoi: Phu San, Thanh Nhan, Dong Da, Saint Paul, and Duc Giang of Hanoi Department of Health by using WHO Infection Control Audit Tool. The results showed that the average performance scores of nosocomial infection control in these hospitals was 46.4/114 (40.7%). Medical waste management achieved at 92% of total scores, SARS prevention at 86.3%, and hand washing practice at 60%. Some activities were incompletely implemented in these five hospitals, such as policies for safe antibiotics use, surveilance of antibiotic-resistant bacterial strains, and preventive measures for special areas. Nosocomial infection control policy, food safety and hygiene, and disinfection and sterilization for medical equipment were 22%, 20% and 20% total standard score, respectively.
Cross Infection ; Infection ; Hospitals

A study of 1544 pupils in Hanoi urban and suburban areas showed that the prevalence of asthma was 10.42%, in which the prevalence in urban area was 12.56%, higher than that in suburban area (7.52%); the prevalence in male pupils were higher than that in female ones. 9.6% cases suffered asthma from under 1 year old. The invidual allergic history, the allergic and asthma history of the family as well as environment factors are strongly associated with the asthma prevalence.
Asthma ; Epidemiology ; Pupil