1.Clinical Observations on Treatment of Hip Osteoarthritis by Electroacupuncture
Xiao ZHENG ; Tao CHE ; Le KUAI
Journal of Acupuncture and Tuina Science 2005;3(2):52-54
To investigate the curative effect of electroacupuncture on hip osteoarth-ritis, 120patients with hip osteoarthritis were randomly divided into two groups, 60 cases each group, and treated by electroacupuncture and oral administration of slow released diclofenac tablet,respectively. The degrees of pain, activity and swelling were observed in both groups before and after treatments. A follow-up was performed for more than 2 years. The curative effects were assessed by JOA criteria for evaluating the effect on hip osteoarthritis. After treatment, the average score increased by 18 marks in the electroacupuncture group and by 12.3 marks in the diclofenac group (P<0.05). Electroacupuncture treatment has a significantly better effect on hip osteoarthritis than oral administration of slow released diclofenac tablet.
2.STUDY ON SIGNIFICANCE OF EXPRESSION OF BASIC FIBROBLAST GROWTH FACTOR AND TUMOR MICROVASCULATURE DENSITY IN RENAL CELL CARCINOMA
Le CHE ; Xuehui YANG ; Jichua ZHU
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
The aim of this study was to investigate the expression of basic fibroblast growth factor (b FGF) and its relationship with tumor microvasogenesis and biological behavior of human renal carcinoma. Gene expression of b FGF was assayed in 20 cases of renal carcinoma tissue using RNA dot blot hybridization. Meanwhile, the protein expression of b FGF and microvasular density (MVD) was assayed in 35 cases of renal carcinoma tissue with immunohistochemical assay. It was found that the expression of b FGF was significantly higher in renal cancer tissue than in normal renal tissue or normal tissue adjacent to the tumor, There was significant correlation between b FGF expression in cancer tissue and clinical stages as well as clinical grades.Similar results were also observed between MVD and b FGF expression in renal cancer tissue. It seemed that b FGF played an important role in angiogenesis in renal carcinoma. Taken together, the results suggest that MVD and the expression of b FGF in renal cancer tissue might be related to the prognosis of renal carcinoma patients.
3.The mechanism of expression of hpoxic induced factor 1? in renal clear carcinoma 786-O cells and its significance
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
0.05). However, the protein expression of HIF-1? was increased remarkably with correspondence to the different hypoxia time (P
4.Diagnosis and treatment of pyelogenic cyst
Le CHE ; Dongquan YANG ; Wenxue SUN ; Guanying DING ; Yanhu ZHANG ; Zengrao NIE
Chinese Journal of General Practitioners 2011;10(7):503-504
The clinical data of 32 patients with pyelogenic cyst were reviewed retrospectively. The diagnosis of 25 cases was confirmed by intravenous pyelography (IVP) , in which the ultrasonography and computed tomography ( CT) failed to provide accurate diagnosis. Eighteen cases were treated by surgical operations, among them 16 cases were cured, one case lost follow-up, and one case recurred in 6 months after surgery. The data indicate that the diagnosis of pyelogenic cyst mainly depends on IVP examination and the laparoscopic technique can be effectively applied for treatment of pyelogenic cyst.
5.Diagnosis and treatment of corpus cavernosum penis rupture
Le CHE ; Dongquan YANG ; Wenxue SUN ; Guanying DING ; Yanhu ZHANG ; Zengrao NIE
Chinese Journal of General Practitioners 2010;09(12):859-860
The clinical data of 16 patients with rupture of corpus cavernosum penis were retrospectively reviewed.The patients were referred to the Department of Urology from January 2005 to November 2009.The causes of penile injury were trauma due to sexual intercourse ( 12 cases), trauma due to masturbatory (2 cases), traffic accidents ( 1 case) and others ( l case).All patients received immediate surgical treatment; 14 out of 16 patients were followed up for a mean period of 3 months.Sexual function was recovered with satisfactory erection in 11 patients, 3 patients complained pain or uncomfortab]eness during erection.Sexual trauma was the main cause of penile fracture.Immediate intervention for penile fracture can achieve satisfactory early and late results.
6.Clinical application of portable echocardiography system in acute paroxysmal dyspnea
Lin CHE ; Ming-Zhong ZHAO ; Ming LUO ; Jin-Fa JIANG ; Bing DENG ; Yuan-Ling LI ; Le-Min WANG ;
Chinese Journal of General Practitioners 2003;0(03):-
Objective To study the clinical value of portable echocardiography system in diagnosis for acute paroxysmal dyspnea.Methods Clinical data of 81 patients with acute paroxysmal dyspnea recorded by a portable echocardiography apparatus at their bedside were retrospectively analyzed,and compared to those of 45 patients by conventional echocardiography.Results The 2D images in portable echocardiograph were similar to those of conventional echocardiograph.Diagnosis could be established in 74 (91.4%),corrected in six (7.4%) and not confirmed only in one (1.2%) of 81 patients with acute paroxysmal dyspnea by portable echocardiography system.And,portable echocardiography system could be used to diagnose pericardial effusion and to monitor perieardial puncturing and draining at bedside. Conclusions Portable echocardiography systems can provide rapid,accurate and valuable information on diagnosis and treatment for acute paroxysmal dyspnea,and make its clinical intervention accurate,scientific and effective,bringing echocardiography performed at bedside possible.
7.Assessing the emergency situation for peripheral vascular wounds/trauma in Viet Duc Hospital from 2004 to 2006
Uoc Huu Nguyen ; Nghia Dinh Che ; Hung Duc Duong ; Hung Quoc Doan ; Huu Cong Nguyen ; Lu Huu Pham ; Tien Anh Do ; Thanh Ngoc Le
Journal of Surgery 2007;4(57):12-19
Background: peripheral vascular wounds/trauma is a severe type of surgical emergency, the increasing rate due to the rapid increase of traffic, labor and living accidents. Subjectives and Method: retrospective study, all patients with peripheral vascular wounds/traumas (alone or combination in multiple trauma) were emergency operated at Viet Duc Hospital from January 2004 to June 2006. Results: A total of 310 patients with peripheral vascular injuries in the study, of which accounted for 62.3% of injury, trauma group accounted for 37.7%. The mean age of 30. In first aid, pressed tape accounted for high rate (71.5%). Rate of popliteal vascular trauma due to fractures around the knee accounted for 65.5%, the rate of brachial vascular trauma with fractures around the elbow was 50%. Rate of late diagnosis of arterial trauma was 14.6%, higher than the arterial wounds (2.6%). The rate of ultrasound for forelimbs - where vessels were many wounds, was lower than that for hindlimbs - where vessels were many traumas (44% vs 67.9%). For vascular wounds, more directly vascular connection and more intervention on veins, whereas, for arterial trauma, more vascular graft. Rate of complications was low (7.4%), with no deaths. Conclusions: Overall, the results of emergency surgery for peripheral vascular wounds/trauma were well. No cases was death from vascular lesions, rate of complications was low.
Blood Vessels/ injuries
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Emergencies
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8.Relationship of left heart size and left ventricular mass with exercise capacity in chronic heart failure.
Yu-Qin SHEN ; Le-Min WANG ; Lin CHE ; Hao-Ming SONG ; Qi-Ping ZHANG
Chinese Medical Journal 2011;124(16):2485-2489
BACKGROUNDImpaired exercise capacity is one of the most common clinical manifestations in patients with chronic heart failure (CHF). The severity of reduced exercise capacity is an indicator of disease prognosis. The aim of the current study was to investigate the association between left heart size and mass with exercise capacity.
METHODSA total of 74 patients were enrolled in the study, with 37 having congestive heart failure (left ventricular ejection fraction (LVEF) < 0.45) and the other 37 with coronary heart disease (by coronary angiography) serving as the control group (LVEF > 0.55). Echocardiography and cardiopulmonary exercise test were performed. The multiply linear regression model was used to evaluate the association between echocardiogrphic indices and exercise capacities.
RESULTSThe study showed that left ventricular end diastolic/systolic diameter (LVEDD/LVESD), left atrial diameter (LAD) and left ventricular mass index (LVMI) were significantly enlarged in patients with chronic heart failure compared with controls (P < 0.01). The VO(2)AT, Peak VO(2), Load AT, and Load Peak in chronic heart failure patients were also significantly reduced compared with controls (P < 0.05), VE/VCO(2) slope was increased in patients with chronic heart failure (P < 0.01). Multivariate linear regression analysis indicated that the patients' exercise capacity was significantly associated with the left heart size and mass, however, the direction and/or strength of the associations sometimes varied in chronic heart failure patients and controls. Load AT correlated negatively with LVEDD in chronic heart failure patients (P = 0.012), while Load AT correlated positively with LVEDD in control patients (P = 0.006). VE/VCO(2) slope correlated positively with LAD (B = 0.477, P < 0.0001) in chronic heart failure patients, while the VE/VCO(2) slope correlated negatively with LAD in control patients (P = 0.009).
CONCLUSIONThe study indicates that the size of LVEDD and LAD are important determinants of exercise capacity in patients with CHF, which may be helpful to identify exercise tolerance for routine monitoring of systolic heart failure.
Aged ; Cardiac Volume ; physiology ; Echocardiography ; Exercise Test ; Exercise Tolerance ; physiology ; Female ; Heart Failure ; physiopathology ; Heart Ventricles ; diagnostic imaging ; pathology ; physiopathology ; Humans ; Male ; Middle Aged ; Radiography
9.Quantitative evaluation of cardiopulmonary functional reserve in treated patients with pulmonary embolism.
Wen-Wen YAN ; Le-Min WANG ; Lin CHE ; Hao-Ming SONG ; Jin-Fa JIANG ; Jia-Hong XU ; Yu-Qin SHEN ; Qi-Ping ZHANG
Chinese Medical Journal 2012;125(3):465-469
BACKGROUNDThere is no research, either at home or abroad, focusing on assessing the cardiopulmonary functional reserve and exercise tolerance in patients with pulmonary embolism (PE), but the benefits of early exercise are well recognized. The goals of this study were to assess cardiopulmonary functional reserve in treated PE patients using the inert gas rebreathing method of the cardiopulmonary exercise test (CPET), and to compare it with traditional methods.
METHODSCPET on the bicycle ergometer were performed in 40 patients with age, gender, body mass index, systolic blood pressure, and pulmonary function matched. The first group was the PE group composed of 16 PE patients (5 male, 11 female) who were given the standard antithrombotic therapy for two weeks. The second group was composed of 24 normal individuals (10 male, 14 female). Both groups were evaluated by cardiac ultrasound examination, 6-minute walking test (6MWT), and CPET.
RESULTS(1) Right ventricular systolic pressure (RVSP) in the PE group increased significantly compared to the control group, (34.81 ± 8.15) mmHg to (19.75 ± 3.47) mmHg (P < 0.01). But neither right atrial end-systolic diameter (RASD) nor right ventricular end-diastolic diameter (RVDD) in the PE patients had changed when compared with the controls. The 6-minute walk distance was significantly reduced in the PE patients compared with normal subjects, (447.81 ± 79.20) m vs. (513.75 ± 31.45) m (P < 0.01). Both anaerobic threshold oxygen consumption (VO(2)AT) and peak oxygen consumption (VO(2)peak) were significantly lower in patients with PE, while CO(2) equivalent ventilation (VE/VCO(2) slope) was higher; VO(2)AT (9.44 ± 3.82) ml×kg(-1)×min(-1) vs. (14.62 ± 2.93) ml×kg(-1)×min(-1) (P < 0.01) and VO2peak (12.26 ± 4.06) ml×kg(-1)×min(-1) vs. (23.46 ± 6.15) ml×kg(-1)×min(-1) (P < 0.01) and VE/VCO(2) slope 35.47 ± 6.66 vs. 26.94 ± 3.16 (P < 0.01). There was no significant difference in resting cardiac output (CO) between the PE and normal groups, whereas peak cardiac output (peak CO) and the difference between exercise and resting cardiac output (ΔCO) were both significantly reduced in the PE group; peak CO (5.97 ± 2.25) L/min to (8.50 ± 3.13) L/min (P < 0.01), ΔCO (1.29 ± 1.59) L/min to (3.97 ± 2.02) L/min (P < 0.01). (2) The 6-minute walk distance did not correlated with CPET except for the VO2 peak in patients with PE, r = 0.675 (P < 0.01).
CONCLUSIONSThe cardiopulmonary functional reserve was reduced in patients with PE. CPET is an accurate, quantitative evaluation of cardiopulmonary functional reserve for PE patients.
Aged ; Exercise Test ; methods ; Exercise Tolerance ; physiology ; Female ; Humans ; Male ; Middle Aged ; Oxygen Consumption ; physiology ; Pulmonary Embolism ; physiopathology ; therapy
10.CD23 mediated the induction of pro-inflammatory cytokines Interleukin-1 beta and tumor necrosis factors-alpha in Aspergillus fumigatus keratitis.
Hai-Jing YAN ; Nan JIANG ; Li-Ting HU ; Qiang XU ; Xu-Dong PENG ; Hua YANG ; Wen-Yi ZHAO ; Le-Yu LYU ; Li-Mei WANG ; Cheng-Ye CHE
Chinese Medical Journal 2021;134(8):1001-1003