1.Pontine toxoplasmosis in an immunocompromised Filipino male: A case report.
Michelangelo D. Liban ; Laurence Kristoffer J. Batino ; Debbie Co Liquete
Philippine Journal of Neurology 2022;25(1):24-27
A 36-year-old-male was admitted complaining of headache, right sided weakness and
numbness of upper and lower extremity, and multiple cranial nerve deficits. Cranial magnetic
resonance imaging revealed an abscess in the pontomesencephalic junction. Patient was then
diagnosed to have Human Immunodeficiency Virus with a CD 4 count of 32 cells/ uL, his CSF
assay was positive for Toxoplasmosis IgG and was managed as a case of probable brainstem
toxoplasmosis. Patient was treated with Co-Trimoxazole 800/160mg 2 tablets twice a day. Upon
discharge the patient clinically improved and was tolerating oral feeding. A repeat cranial
magnetic resonance imaging after 6 weeks of antibiotic treatment revealed a decrease of size in
the previous lesion. To our knowledge, there are no reported cases in the Philippines that shows
the documentation of CNS toxoplasmosis in the brainstem. In this paper, a case of CNS
toxoplasmosis in the pons of a newly diagnosed HIV patient is presented and how its course led
to a good outcome.
Toxoplasmosis
;
Immunocompromised Host
2.Neurologic imaging of COVID-19 patients in a tertiary referral hospital in the Philippines: A retrospective study.
Laurence Kristoffer Batino ; Leah Theresa Q. Cortez ; Manolo Kristoffer Flores
Philippine Journal of Neurology 2022;25(1):17-23
BACKGROUND:
Coronavirus (COVID-19) is a recently discovered disease caused by severe acute
respiratory syndrome COV2 virus (SARS COV-2) that led to a global pandemic. COVID-19, with
its rapid spread, proved to be a global threat to health. Although it is known to mainly cause
respiratory symptoms, neurologic sequelae have also been reported in a growing number of
patients.
OBJECTIVES:
This study aims to provide additional evidence regarding neuro-radiographic
findings among Filipino patients inflicted with COVID-19.
METHODOLOGY:
This paper is an analytical, retrospective study of COVID-19 confirmed patients
who presented with neurologic manifestation and underwent cranial CT scans between April
2020 and April 2021 at Baguio General Hospital and Medical Center.
RESULTS:
A total of 22 patients were included in the study. Of these, 11 had acute infarcts, 5 had
cerebral hemorrhage, 1 had cerebral venous thrombosis, and 5 had normal imaging findings.
Fisher's test was done and revealed a significant difference between COVID-19 severity and
abnormal CT scan findings.
CONCLUSION
Although relatively uncommon, the study showed that there is an increased
incidence of abnormal neuroimaging findings among patients with COVID-19. The most
common of which is cerebral infarction followed by macrohemorrhages. The severity of the
disease is correlated with the increased incidence of abnormal neuroimaging findings among
COVID-19 patients.
Neuroimaging
3.Thirteen-and-a-Half syndrome stroke: A case report.
Laurence Kristoffer J. Batino ; Golden Tamon-Gayo ; Randolf John Fangonilo
Philippine Journal of Neurology 2021;24(2):14-16
We describe a 52-year old woman who developed one- and-a-half syndrome with an ipsilateral
trigeminal and facial nerve palsy from a lacunar infarct of the left paramedian pontine area
likely involving the median-paramedian perforators of the basilar artery.
Stroke, Lacunar
;
Brain Stem