Little has been known about what pathways subserve mirth and its expression laughter. We report two patients with cryptogenic gelastic seizures who provide some insight into the mechanisms of laughter. Invasive video-EEG monitoring showed ictal onset zone to be either in the left or right medial frontal cortex. After resection of the medial frontal area, including the epileptogenic focus, patients have been in gelastic seizure-free state. This suggests the possibility that medial frontal cortex is involved in the motor act of laughter.
Humans ; Laughter ; Seizures*

PURPOSE: This study examines the difference of optimism, self-esteem and depression to verify an effect of laughter therapy program for menopausal women. METHODS: A quasi-experimental nonequivalent control group pre / post-test design was used. The participants (n=57) were 28 in the experimental group and 29 in the control group. The data were collected in December of 2011. The experimental group participated in laughter therapy for 30 min per session, five times a week for the period of 2 weeks. The questionnaires were used to measure pre / post-test optimism, self-esteem, and depression of menopausal women. RESULTS: The results showed that laughter therapy was effective in increasing optimism (p=.020) and self-esteem (p<.001). And the depression of menopausal women decreased (p=.003). CONCLUSION: The result of the study indicates that laughter therapy for menopausal women may be an effective nursing intervention to improve optimism, self-esteem and depression of menopausal women.
Depression ; Female ; Humans ; Laughter ; Laughter Therapy ; Menopause ; Surveys and Questionnaires

PURPOSE: The purpose of this study was to investigate Laughter Index, depression and anxiety in middle-aged women. METHOD: The data were collected from 622 middle-aged women by means of structured questionnaire. The data were analyzed using descriptive analysis, t-test, one-way ANOVA, Pearson correlation analysis by SPSS version 10. RESULTS: The measuring of respondents' laughter index revealed they scored an average of 94.75 (+/-16.13) of the full score 150. The measuring of respondents' depression showed they marked an average of 42.69 (+/-7.72) of the full score 80. The measuring of respondents' anxiety showed they marked an average of 42.03 (+/-9.48) of the full score 80. Respondents statistically showed the significant difference in their laughter index depending on age(t=.917, p=.000), and economic status(F=21.710, p=.000). Respondents statistically revealed the significant difference in depression depending on religion(F=3.396, p=.018), economic status(F=13.660, p=.000). Respondents statistically revealed the significant difference in anxiety depending on religion(F=5.557, p=.001), economic status(F=16.79, p=.000). The laughter index related to depression and anxiety in middle-aged women were significantly correlated. CONCLUSION: This study showed that laughter index in middle-aged women was correlated negatively depression and anxiety. Further research is regarded as necessary to evaluate and to compare effects of laughter with physical health status.
Anxiety* ; Depression* ; Female ; Humans ; Laughter* ; Surveys and Questionnaires

PURPOSE: The purpose of this study was to examine the effects of laughter therapy on mood, state anxiety, and serum cortisol based on a Stress-Coping Model for preoperative breast cancer patients. METHODS: The study used a nonequivalent control group pretest-posttest design. The participants were 40 breast cancer patients who were admitted to one general hospital for surgery in 2009 (experimental group 23, control group 17). The experimental group received one hour laughter therapy consisting of dance, lots of laughter techniques, and meditation. RESULTS: The mean ages were 47 years (experimental group) and 49 years (control group). There were no significant differences in demographic and disease-related characteristics between the two groups. After the intervention, the scores of mood and state-anxiety of experimental group were significantly improved than those of control group. However, no difference was found in serum cortisol. CONCLUSION: The laughter therapy was partially effective in improving stress response in patients with breast cancer. Further research is needed to develop and evaluate the longer periods of interventions to testify the effects on serum cortisol, and other biochemical variables.
Anxiety ; Breast ; Breast Neoplasms ; Hospitals, General ; Humans ; Hydrocortisone ; Laughter ; Laughter Therapy

PURPOSE: The purpose of this study is to investigate the effects of visiting laughter therapy on depression and insomnia in the vulnerable elderly. METHODS: A quasi-experimental nonequivalent control group pretest-posttest design was used for this study. The participants were 87 elderly who were registered in the Tailored Visiting Health Program of public health centers. Data were collected from September to November 2010. The experimental group received visiting laughter therapy froma visiting nurse who had taken laughter training provided by laughter therapy experts. The experimental group received 10~15 min of laughter therapy once a week for 8 weeks. The instruments included Geriatric Depression Scale and Insomnia Severity Index to measure depression and sleep problems before and after the laughter therapy. RESULTS: The results showed that visiting laughter therapy was effective in decreasing depression and insomnia among the vulnerable elderly. CONCLUSION: These findings indicate that laughter therapy may be an effective nursing intervention to improve depression and insomnia Further studies would be needed to identify the difference of effects according to time, interval, or period of visiting laughter therapy and to evaluate the lasting effect of visiting laughter therapy.
Aged ; Community Health Nursing ; Depression ; Humans ; Laughter ; Laughter Therapy ; Public Health ; Sleep Initiation and Maintenance Disorders

PURPOSE: The purpose of this study was to examine the effect of laughter therapy on arthralgia, ankylosis, depression and sleep of elderly housebound women suffering from osteoarthritis. METHODS: The study used a nonequivalent control group pretest-posttest design. The participants were 48 elderly women: 23 in the experimental group and 25 in the control group. The experimental group received laughter therapy twice a week for 4 weeks. The results were analyzed by using chi2-test, ANCOVA, and t-test with the SPSS/WIN 21.0 program. RESULTS: The results showed that laughter therapy had a significant statistical effective in reducing arthralgia, ankylosis, and depression and improving the quality of sleep as evidenced by the differences between the two groups. CONCLUSION: The results of this study indicated that laughter therapy is an effective nursing intervention reducing arthralgia, ankylosis, and depression and improving the quality of sleep in these women. Therefore, it is necessary to develop laughter therapy as an independent nursing intervention for elderly women with osteoarthritis who are housebound.
Aged* ; Ankylosis* ; Arthralgia* ; Depression* ; Female ; Humans ; Laughter Therapy* ; Laughter* ; Nursing ; Osteoarthritis*

PURPOSE: The purpose of this study was to examine the effect of a laughter therapy on pain, depression, and quality of life of elderly people with osteoarthritis. METHODS: A quasi-experimental, nonequivalent control group pretest-posttest design was used. Participants (n=60) included older adults who were diagnosed with osteoarthritis and received treatment at the out patient departments of two different hospitals. Data were collected from March 9 to 30, 2011. Experimental group (n=30) participated in laughter therapy four times, once a week for 50 min per session. Questionnaires were used to measure pretest and posttest levels of pain, depression, and quality of life. RESULTS: At the end of four-week intervention, pain (F=11.32, p=.001) and depression (F=10.77, p=.002) were significantly decreased in the experimental group. Quality of life (F=6.28, p=.015) were significantly improve in the experimental group. CONCLUSION: The study results suggest that the laughter therapy is an effective intervention to reduce the pain and depression, and to improve quality of life. It seems that this program can widely be utilized as one of nursing intervention programs for the elderly people with osteoarthritis.
Adult ; Aged* ; Depression* ; Humans ; Laughter Therapy* ; Laughter* ; Nursing ; Osteoarthritis* ; Quality of Life* ; Surveys and Questionnaires

PURPOSE: The study was a non-equivalent control group, quasi-experimental study to find out the effect of the laughter therapy on anxiety and depression of burn patients. METHODS: Study subjects were 60 hospitalized patients with the diagnosis of 2nd degree burn (30 experimental group; 30 control group). Experimental group received laughter therapy by the certificated therapist. STAI questionnaire, blood pressure and pulse were checked before and after the laughter therapy. RESULTS: Before and after the laughter implementation, the experimental group's anxiety decreased, however, the comparison group's anxiety did not show significant difference. Moreover, experimental group's anxiety decreased after the implementation. Experimental group's systolic blood pressure and diastolic blood pressure did not decrease pre/post laughter therapy mediator. The comparison group showed that systolic blood pressure increased, and diastolic blood pressure did not show significant difference. Also, experimental group's systolic blood pressure and diastolic pressure did not show significant difference after the treatment. Pre/post laughter therapy mediation did not decrease the experimental group's pulse and comparison group's pulse. Furthermore, the experimental group's pulse did not show the significant difference after the treatment. In pre/post laughter therapy mediation, the experimental group's depression was decreased, however, the comparison did not how significance difference in pre/post depression score after the treatment. Moreover, the experimental group's depression was decreased after the treatment. CONCLUSION: According the results above, the laughter therapy had effect on decreasing anxiety and depression of the burn patients and it is efficient mediator for the burn patient. Repetitive research was needed to investigate the effect of laughter on cardiovascular system since it did not have decreasing effect on the blood pressure and pulse.
Anxiety* ; Blood Pressure ; Burns* ; Cardiovascular System ; Depression* ; Diagnosis ; Humans ; Laughter ; Laughter Therapy* ; Negotiating ; Surveys and Questionnaires

BACKGROUND: Aging process causes several changes in the typical sleep patterns. Elderly people complain frequently about sleep duration, changes of sleep/wake rhythm and day time sleepiness. This study was performed to evaluate improvement of sleep quality after laughter therapy. METHODS: On July 2007, the study participants aged over 65 were recruited through a community center in Daegu. There were 48 subjects in the experimental group and 61 in the control group. The laughter therapy program was applied to the experimental group. We compared Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI) before and after laughter therapy. Data were analyzed by independent t-test, chi-square test, paired t-test, and ANCOVA using SPSS windows ver. 14.0. RESULTS: At initial study, there were no significant differences in baseline characteristics. The ISI scores were 8.00 +/- 6.29 and 8.36 +/- 6.38; the PSQI scores were 6.98 +/- 3.41 and 7.38 +/- 3.70; The Geriatric Depression Seals (GDS) scores were 7.98 +/- 3.58 and 8.08 +/- 3.95 in experimental and control groups, respectively. After laughter therapy, the ISI scores were 7.58 +/- 5.38 (P = 0.327) and 9.31 +/- 6.35 (P = 0.019), PSQI scores were 6.04 +/- 2.35 (P = 0.019) and 7.30 +/- 3.74 (P = 0.847), GDS scores were 6.94 +/- 3.19 (P = 0.027), 8.43 +/- 3.44 (P = 0.422) in experimental and control groups, respectively. CONCLUSION: The laughter therapy is considered to be useful for the elderly people in a community that improves insomnia and sleep quality.
Aged ; Aging ; Depression ; Humans ; Laughter ; Laughter Therapy ; Sleep Initiation and Maintenance Disorders

PURPOSE: The purpose of this study was to investigate the of laughter therapy on depression, anxiety, and stress among patients underwent radiotherapy. METHODS: Participants in the study were comprised of 60 breast cancer outpatients who received radiotherapy. Thirty-one of the patients were assigned in the experimental group and the other 29 patients made up the control group. Laughter therapy was consisted of the delivery of information and active motion resulting in laughter. We provided laughter therapy 4 times for 2 weeks. Each session lasted 60 min. The experimental group received laughter therapy intervention as a group. An average attendance frequency per person was 2.7. To evaluate the effect of laughter therapy, the degrees of depression and anxiety were measured by Hospital Anxiety and Depression (HAD) and stress was measured by the Brief Encounter Psychosocial Instrument (BEPSI). Data analysis included a 2-test, t-test, and Fisher's exact test using SPSS 12.0 and SAS 8.0. RESULTS: There was significant decrease in the degrees of depression, anxiety, and stress in the experimental group compared to those in the control group (p<.01, p=.04, and p<.01, respectively). CONCLUSION: This study provides evidence that laughter therapy is an effective intervention in improving depression, anxiety, and stress in breast cancer patients.
Anxiety ; Breast ; Breast Neoplasms ; Depression ; Humans ; Laughter ; Laughter Therapy ; Outpatients ; Phenothiazines ; Statistics as Topic