No abstract available.
Cicatrix* ; Lasers, Dye* ; Sarcoidosis*

No abstract available.
Dermoscopy ; Hemangioma* ; Lasers, Dye

No abstract available.
Lasers, Dye* ; Melanosis*

BACKGROUND: Some warts prove resistant to multiple therapies, particularly on an immunosuppressed patient. A previous study revealed that combination therapy with pulsed dye laser and intralesional bleomycin was effective on recalcitrant warts. OBJECTIVE: The aim of this study was to confirm whether the combination therapy with pulsed dye laser and intralesional bleomycin was effective for the treatment of recalcitrant warts. METHOD: Fifteen patients, all with recalcitrant warts, were recruited. Two patients were on long-term immunosuppressant drugs. Twenty warts were treated in total. The warts were anaesthetized with local anesthetic cream (EMLA(R) 5% cream) then treated with a pulsed dye laser (5mm spot, fluence 9.5-10J/cm2). Immediately following this, bleomycin (1mg/ml) was injected into the base of the warts. At 3-4 weeks after the last treatment, the warts were evaluated to assess clearance rate, total treatment numbers and side effects. RESULT: 1. Complete clearance was achieved for 17 out of 20 warts (85%). 2. Partial clearance was achieved for 3 out of 20 warts (15%). 3. Recalcitrant warts were cleared with an average of 1.95 treatments. 4. Recalcitrant warts on the immunosuppressed patients were cleared with an average of 2.0 treatments. 5. No significant side effects were observed. CONCLUSION: Combination therapy with the pulsed dye laser and intralesional bleomycin appears to be a safe, rapid, well tolerated and successful treatment for recalcitrant warts. It also appears to be effective for recalcitrant warts on immunosuppressed patients.
Bleomycin* ; Humans ; Lasers, Dye* ; Warts*

BACKGROUND: Periungual warts are a therapeutic challenge. Many studies have revealed that intralesional interferon α-2b therapy and pulsed dye laser therapy have numerous advantages over other modalities of theratment. OBJECTIVE: The purpose of this study was to determine if combination therapy with intralesional interferon α-2b and pulsed dye laser might offer an effective treatment for periungual warts. METHODS: Thirty-three patients were randomly assigned to one of three study groups. In group A, the patients received both intralesional interferon α-2b treatment and pulsed dye laser(PDL) therapy (n=13). Group B patients were treated wit intralesional interferon α-2b alone (n=10) and group C was done with PDL therapy only (n=10). RESULTS: The clearance rate was 92.3% for the patients treated with the combination therapy of intralesional interferon α-2b treatment and pulsed dye laser (PDL) therapy. It was 50% for the patients with the intralesional interferon α-2b treatment alone, and 0% for the group with the PDL therpy only. No significant side effects were observed. At 6 months after cessation of the therapy, total 2 cases (one from group A and the other from group B) were recurred. CONCLUSION: The combination therapy with intralesional interferon α-2b treatment and pulsed dye laser therapy was highly effective for the treatment of recalcitrant periungual warts.
Humans ; Interferons* ; Lasers, Dye* ; Warts*

BACKGROUND: Warts are common virus-induced lesions that are troublesome to treat, especially in children. Recently, some trials have suggested that the pulsed dye laser may also be useful for the treatment of warts. OBJECTIVE: To determine the effectiveness and safety of 585nm flashlamp-pumped pulsed dye laser treatment of warts. METHODS: Fifty patients representing a total of 265 warts were recruited for the study. Patients were treated using the flashlamp-pumped pulsed dye laser with a pulse duration of 450 sec, a spot size of 5mm, and energy fluence ranging between 7 to 9 J/cm2. Patients in whom no visible evidence of warts remained before 5 treatment sessions were classified as 'cured'. RESULTS: The cure rates were 89% for hand warts, 21% for plantar warts, 58% for periungual or subungual warts, 98% for limb warts and 100% for facial warts. Significant difference in the clearance rate of warts was found according to the maximum diameter of warts (≤0.3cm, >0.3cm) (<0.05). CONCLUSION: The 585nm flashlamp-pumped pulsed dye laser had potential effectiveness for the treatment of small warts on the hands, face, and limbs, but it is less effective for plan-tar warts, or larger warts.
Child ; Extremities ; Hand ; Humans ; Lasers, Dye* ; Warts*

Subretinal neovascular membrane associated with retinochoroidal colooma is a rare finding. The authors report a case of retinochoroidal coloboma associated with subretinal neovascular membrane, which was treated with Yellow Dye laser photocoagulation (wave length: 590 nm, spot size: 150-200 micro gram, power: 200-300 mW, shooting time: 60, G3 coagulation).
Coloboma* ; Lasers, Dye ; Light Coagulation ; Membranes*

Striae Distensae is a very common cosmetic problem. The effectiveness of various lasers, such as the 585-nm pulsed dye laser on the treatment of striae distensae has recently been reported. However, the potential pigmentary alteration of dark skin by pulsed dye laser is known. Thermage is a radiofrequency capable of delivering higher energy fluences to a greater volume of tissue than nonablative lasers, with no epidermal injury. We report three patients who had striae distensae. They were treated with Thermage and 585-nm pulsed dye laser. The treatment was effective and safe for dark skin.
Humans ; Lasers, Dye ; Skin ; Striae Distensae*

Xanthelasma palpebrum is the most common type of xanthoma that develops mainly on the inner epicanthus of upper eyelids with symmetrical distribution. The lesion tends to be permanent, progressive and cosmetically disfiguring. The recommended treatment has been surgical excision, local treatment with chemicals, and carbon dioxide laser. All of the mentioned treatment have some disadvantages including scarring, pigmentary change and need for local anesthesia. We describe the treatment of xanthelasma palpebrum with the pulsed dye laser which coagulates the hyperpermeable vessels so that the lipid leakage could be blocked and prevent recurrence and further progression.
Anesthesia, Local ; Cicatrix ; Eyelids ; Lasers, Dye* ; Lasers, Gas ; Recurrence ; Xanthomatosis

BACKGROUND: Viral warts are benign epithelial proliferations induced by the human papillomavirus (HPV) and they affect 7~10% of the population. Some warts such as periungual warts are resistant to various treatment modalities, including cryotherapy, surgical excision, carbon dioxide laser therapy and immune therapy. Thus, some studies have reported that pulsed dye laser has been effectively used for treating recalcitrant warts. OBJECTIVE: The purpose of this study was to evaluate the therapeutic response and safety of pulsed dye laser using high fluence for the treatment of periungual warts. METHODS: 66 periungual warts on 28 patients were treated with pulsed dye laser. The treatment parameters were a spot size of 5.0 mm, a pulse duration of 0.45~1.5 ms and a fluence of 14.0~15.0 J/cm2. The warts were evaluated at 2~3 week intervals to assess the clearance rate and side effects. RESULTS: Complete clearance was achieved for 47 out of 66 periungual warts (71.2%). The average number of treatment sessions was 2 (range: 1~6). After the first session, complete clearance was achieved for 24 out of 66 warts (36.4%). No significant side effects were observed except for pain during and after the procedure. During a median follow up period of 7 months (range: 3~15 months), 10 periungual warts on 3 patients recurred. CONCLUSION: Pulsed dye laser using high fluence could be used as a safe and successful treatment for recalcitrant periungual warts.
Cryotherapy ; Follow-Up Studies ; Humans ; Lasers, Dye ; Lasers, Gas ; Warts