The selenium levels in plasma and liver of rats suffered from 3rd degree burn of 20% BSA on dorsum were significantly decreased, plasma VE dropped too, while the VE contents of RBC and liver were as high as those in control group. After giving 2.3?g selenium/100g bw as selenite to the burned rats, the VE contents of RBC and liver as well as plasma were then decreased as compared with control. The content of plasma total sulfhydryl group decreased more in selenium-supplemented group than in burned control.These results indicated that the requirement of VE probably increased after supplementation of selenium in burned rats.

The ascorbic acid in plasma was determined on the basis of reduction of ferric to ferrous ion and its formation of a colored complex with batho-phenanthroline. This method was highly correlated to Roe's dinitrophe-nylhydrazine method in the determination of plasma ascorbic acid of 16 normal adults and the correlation coefficient was 0.90. By animal experiment the new method may be used to discriminate different levels of plasma ascorbic acid. It is rather simple and water bath is not required. Only 0.25ml of plasma is needed for each determination. So this method is useful in assessing the ascorbic acid nutriture in tield survey.

To study the effect of soybean isoflavones(SI) on thymocytes in irradiated mice. Method: Ninety male mice were randomly divided into control group, irradiated group, irradiated plus 0.5% dose SI group. After 2w feeding, the mice received 4.0 Gy 137Cs ?-radiation. The cell cycles,cell apoptosis and proliferation of thymocytes and thymus index were observed in irradiated mice after 12h, 24h, 1w and 2w. Results: After the mice were irradiated, the thymus became significantly atrophic, and the rate of cell apoptos and the cell cycles of G0-G1 phase in thymocytes were significantly increased (P

Objective To explore the status quo of medication belief in the patients with myasthenia gravis and analyze their influencing factors,so as to provide reference for health care professionals to develop targeted interventions.Methods A total of 145 patients with myasthenia gravis visiting the First Affiliated Hospital of Guangzhou University of Chinese Medicine from July 2021 to March 2022 were selected.The Be-liefs about Medicines Questionnaire(BMQ)was used to investigate.The multiple linear regression was used to analyze the relevant influencing factors.Results The scores of medication belief,necessity belief and con-cern belief in 145 patients were(4.17±1.23)points,(19.52±3.45)points and(18.29±4.26)points respec-tively.There was statistically significant difference between the scores of necessity belief and concern belief(P＜0.05).The education level,financial burden,duration of illness,length of medication,number of recur-rent hospitalizations,and inappropriate medication-induced exacerbations had influence on the medication be-lief scores of the patients with myasthenia gravis(P＜0.05).The duration of illness,length of medication and number of recurrent hospitalizations had the influence on the medication necessity scores of patients with my-asthenia gravis(P＜0.05).The financial burden had the influence on the medication concerns scores of the patients with myasthenia gravis(P＜0.05).Conclusion The medication belief in the patient swith myasthe-nia gravis is at a low level,and the number of recurrent hospitalizations and financial burden are the independ-ent risk factors affecting the medication belief scores in the patients with myasthenia gravis.The number of recurrent hospitalizations is an independent risk factor for the score of medication necessity dimension.

Myasthenia gravis crisis (MC) often involves respiratory muscles and requires mechanical ventilation urgently. As non-invasive mechanical ventilation (NIV) technology unceasing development, its use in acute respiratory failure caused by MC shows obvious advantages. However, how to identify the occurrence of MC at early stage, predict the relevant indicators of NIV for MC treatment, and apply different ventilation strategies to improve the effect of treatment are worthy of attention. In addition, the new development of NIV modes in recent years also provides new direction for the treatment of MC. Therefore, this article reviews recent advance in the clinical application of NIV in MC to provide clinical references.