1.A hemodynamic animal model of distal ends of internal mammary artery and vein
Lanhua MU ; Yuanbo LIU ; Lianqing ZHANG
Chinese Journal of Medical Aesthetics and Cosmetology 2002;0(02):-
Objective To verify the ability of distal ends of internal mammary artery and vein used as recipient vessels on breast and chest wall reconstruction. Methods Four bilateral (left 2 and right 2) scent pig buttock island flaps pedicled circle deep iliac artery and vein were used by comparing the different hemodynamic parameters (pressure; flux volume; perfusion unions) between the original pedicl artery (deep iliac artery), proximal and distal ends of internal mammary artery. The free flaps were transplantated by anastomosed end-end to the distal-ends of internal mammary artery and vein after the proximal ends were ligated. Results The pressure of distal end of internal mammary artery was 61%-65% of the pressure with original pedicl artery (deep iliac artery), the immediate volume of anastomasis stoma was a little lower than that of original pedicl artery. The flap, 15 cm?30 cm?2 cm in size, completely survived more than 14 days after operation. Conclusion The slightly decreased distal arterial pressure does not compromise flap survival. Bilateral scent pig buttock island flap pedicled circle deep iliac artery and vein is an ideal animal flap model. This hymodynamic model can be widely used .
2.Percutaneous trans-hepatic Cyanoacrylate embolization for gastric varices
Lei WU ; Lanhua LI ; Chunqing ZHANG ; Fuli LIU ; Qiang ZHU ; Hongwei XU ; Kai FENG ; Jiyong LIU
Chinese Journal of Digestive Endoscopy 2009;26(11):580-583
Objective To evaluate the efficacy of percutaneouse trans-hepatic Cyanoacrylate (TH glue) embolization for gastric varices. Methods TH glue was injected into the gastric varices and its feeder veins in 30 patients. The endoscopy was performed at 1 week and every 3 months after the procedure, while the CT and portal vein angiography were performed at 3 months and every 6 months after the procedure to e-valuate the oblitazation results. Results The effective rate of treatment was 100%. A total of 21 patients were followed up in a mean period of 27.9 months (11-33 months) with a recurrence rate of varices at 14. 29% (3/21). Portal hypertensive gastropathy was observed in 17 patients (80. 95%), and to-bleeding occurred in 2 patients (9. 52%) due to portal hypertensive gastropathy. CT and portal vein angiography dis-played TH glue in fundic peripheral veins, perforating veins in the gastric wall and other feeding veins with-out re-ciroulation or new branches after embolization. Conclusion Peroutaneous trans-hepatic TH glue is a-ble to embolize the gastric varices and its feeding veins, which is feasible and effective in treatment of gastric varices.
3.Clinical study of compound glutamine for adjuvant therapy after radical surgery in gastric cancer
Fuli WANG ; Lanhua WANG ; Wei JIANG ; Aifeng ZHU ; Ming LI ; Jiandong ZHANG
Journal of International Oncology 2015;42(11):813-816
Objective To evaluate the clinical effect of compound glutamine in the adjuvant treatment after radical surgery of gastric cancer.Methods A total of 63 cases with gastric cancer after radical resection were randomly divided into treatment group and control group, according to random number table.32 patients in treatment group received simultaneous three-dimensional conformal radiotherapy with capecitabine monotherapy regimen, while oral administration of compound glutamine enteric-coated capsules.31 cases in control group only received chemoradiotherapy.Results In treatment group, the quality of life score for the excellent and good accounted for 40.6% and 34.4%, significantly higher than 16.1% and 12.9% in control group respectively (x2 =4.63, P =0.03;x2 =4.00, P =0.04).The incidence of nausea and vomiting, abdominal pain and diarrhea in treatment group respectively were 31.3% and 37.5% , significantly less than 61.3% and 64.5% in control group with statistical significance (x2 =5.72, P =0.02;x2 =4.60, P =0.03).The incidence of gastrointestinal reactions in treatment group were mainly Ⅰ and Ⅱ degrees, and Ⅲ-Ⅳ degree of gastrointestinal reactions were not appear.While the antidiarrheal drugs (21.9% vs.48.4%) and analgesics drugs (15.6% vs.38.7%) in the treatment group were significantly reduced compared with the control group (x2 =4.87, P =0.03;x2 =4.26, P =0.04).Conclusion By administration of compound glutamine in the course of adjuvant chemotherapy after radical surgery of gastric cancer can improve the quality of life, reduce chemotherapy-induced gastrointestinal side effects, improve treatment compliance, and successfully complete the treatment.
4.Investigation of tick bites in outpatients with fever from health care facilities in Tengchong County
Lanhua LI ; Shengguo LI ; Jiazhi WANG ; Xishang LI ; Dan ZHU ; Wenqi SHI ; Yi ZHANG ; Xiaonong ZHOU
Chinese Journal of Schistosomiasis Control 2016;28(3):323-326
Objective To study the prevalence of tick bites and relative factors of outpatients with fever from health care fa?cilities in Tengchong County. Methods From July to August,2014,the outpatients with fever in five health care facilities namely Tengchong Center for Disease Control and Prevention,Hehua Health Center,Jietou Health Center,Qushi Health Cen?ter and Xinhua Health Center were investigated by questionnaires. The factors related to tick bites were explored with the univari?ate analysis and multiple regression models. Results Totally 884 effect questionnaires were acquired. Among the 884 partici?pants,85(9.6%)had experienced tick bites. The frequency of tick bites was associated with locations,gender,age group,own?ership of cattle,working at foreign country,firewood cutting and lumbering in the forest(all P<0.05). The multiple regression revealed that the male and people raising cattle,working at foreign country,engaging in firewood cutting and lumbering in the forest had a more risk for tick bites. Conclusions Tick bites are common in the residents of Tengchong County. The risk of be?ing bitten varies in different populations. The local health departments should promote health education in the high?risk popula?tion to reduce the risk of infecting tick?borne diseases.
5.EFFECT OF Se-SUPPLEMENTATION ON MONOAMINE OXIDASE ACTIVITY IN MYOCARDIAL MITOCHONDRIA OF RATS FED ON GRAINS FROM KESHAN DISEASE AREA
Lanhua ZHOU ; Gaofeng FAN ; Guanglu XU ; Shichen WANG ; Shichen WANG ; Kai ZHANG
Acta Nutrimenta Sinica 1956;0(01):-
Three groups of Sprague-Dawley rats were fed on low-Se diet frow Keshan disease area, Se-supplemented diet and stock diet respectively, for observing the effect of Se on mitochoadrial monoamine oxidase (MAO) activities in myocardia. The results showed that cardiac mitochondrial MAO activities in the Se-deficient group were significantly decreased as compared to both the Se-supplemented and stock diet group, and Se content in plasma and GSH-Px activity in. red blood cells also were significantly reduced at 30, 60 and 90 days of feeding. In Se-supplemented group MAO and GSH-Px activities as well as Se content were comparable to levels in the stock diet group.
6.A case-control study on risk factors for low birth weight in China.
Xinli ZHANG ; Yulin LIU ; Liangming LIN ; Lanhua CAO ; Jie MI
Chinese Journal of Preventive Medicine 2002;36(3):158-160
OBJECTIVETo identify the risk factors for low birth weight (LBW) in Chinese newborns with varied characteristics.
METHODSA 1:1 matched case-control study, with 999 babies of LBW was performed in 44 counties of 11 provinces in China during July to October, 1998 for identifying their risk factors using simple and multivariate logistic regression models.
RESULTSThe determinants of LBW in China included factors, such as multiparity (OR = 106.9), preterm birth (OR = 18.7), abnormal maternal health status (OR = 2.61) and maternal malnutrition (OR = 3.42), maternal medical conditions during pregnancy (OR = 1.93), maternal schooling (OR = 1.43), et al. Distribution of the risk factors for LBW was significantly different between coastal, inland and remote areas. LBW was mainly attributed to intrauterine growth retardation (IUGR) (71.6%) in the rural areas, and to multiparity and preterm birth, in addition to IUGR, in the urban areas. There was different in the risk factors for LBW with preterm births and IUGR.
CONCLUSIONSIt is an effective way to reduce incidence of low birth weight in China that all measures for prevention and control should be relevant to its risk factors.
Case-Control Studies ; China ; Female ; Humans ; Incidence ; Infant, Low Birth Weight ; Infant, Newborn ; Logistic Models ; Male ; Multivariate Analysis ; Pregnancy ; Risk Factors
7.A national sampling survey on birth weight in 1998 in China: mean value and standard deviation.
Jie MI ; Liangming LIN ; Yulin LIU ; Xinli ZHANG ; Lanhua CAO
Chinese Journal of Preventive Medicine 2002;36(3):154-157
OBJECTIVETo understand the distribution of live birth weight in China.
METHODSA national survey on live birth weight was performed during July-October, 1998 in China, with stratified sampling. Totally, 22 350 live newborns (11 584 males and 10 766 females) with 28 weeks or more of gestation were measured for their birth weight in the sampling sites during 1998.
RESULTSThe ratio of male to female newborns measured was 1.08. The rates of multiple birth and preterm birth (< 37 weeks of gestation) were 1.8% and 3.5%, respectively. Live birth weight was higher in the urban areas (3 301 g) than that in the rural area (3 225 g) (t = 9.4. P < 0.001), the highest in the coastal areas (3 262 g), middle in the inland areas (3 254 g) and the lowest in the remote areas (3 115 g) (F = 177.9, P < 0.001), with a decreasing trend. Live birth weight in the first-class rural areas approximated to that in the urban areas, and that in the second-class, third-class and fourth-class rural areas decreased significantly. The average live birth weight in the fourth-class rural areas was 200 g lower than that in the urban areas.
CONCLUSIONSGenerally, the average live birth weight in China was closed to that in the developed countries. But, a big difference in the average live birth weight between regions with varied economic development and health care condition was observed. An intervention measure should be implemented in the poverty-stricken rural areas to increase their average live birth weight.
Birth Weight ; China ; Data Interpretation, Statistical ; Female ; Humans ; Male ; Population Surveillance ; Pregnancy ; Pregnancy Rate
8.Sampling survey on low-birth weight in China in 1998.
Liangming LIN ; Yulin LIU ; Xinli ZHANG ; Jie MI ; Lanhua CAO
Chinese Journal of Preventive Medicine 2002;36(3):149-153
OBJECTIVETo study the weight of live births and incidence of low-birth weight (LBW) in China.
METHODSA national survey on the weight of live births with gestational ages of 28 weeks or over in 16 cities and 28 counties of 11 provinces in China was carried with stratified sampling during July to October, 1998.
RESULTSTotally 22 350 live newborns, 11 584 males and 10 766 females, with gestational ages of 28 weeks or more in sampling sites were measured at their birth. Rates of multiple births and preterm birth (< 37 weeks of gestation) were 1.8% and 3.5%, respectively. LBW rates were 4.20% and 6.26% for urban and rural areas, respectively, with a national weighted-average of 5.87%. Full term births (>/= 37 weeks of gestation) accounted for 61.2% and 71.6% of the babies with LBW in national and rural areas, respectively. Their average birth weight was 3 301 g and 3 225 g in urban and rural areas, respectively, with statistically significant difference, and 3 280 g and 3 173 g for boys and girls, respectively, approaching to the values recommended by the World Health Organization (WHO). Live birth weight in the coastal, inland, and remote areas appeared a trend of gradual decrease. Early neonatal mortality of babies with LBW was 50.0 per thousand and 179.4 per thousand in urban and rural areas, respectively, with a national average of 151.5 per thousand, significant higher than those with normal birth weight.
CONCLUSIONSThe average birth weight and LBW rate in live births of China were close to those in the developed countries, and there was significant difference in them between varied regions. The majority of LBW in China was attributed to intrauterine growth retardation (IUGR). Early neonatal mortality in babies with LBW was significantly higher than that with normal birth weight. Further intervention measures should be implemented.
China ; Female ; Health Surveys ; Humans ; Incidence ; Infant Mortality ; Infant, Low Birth Weight ; Infant, Newborn ; Male
9.Clinical study of eurycoma longifolia in treatment of erectile dysfunction in climacteric males
Liguo LIN ; Wenjie WANG ; Jiaofei ZHANG ; Lanhua TANG
Chongqing Medicine 2018;47(9):1204-1206,1209
Objective To investigate the effect and safety of eurycoma longifolia in the treatment of erectile dysfunction(ED) in climacteric males.Methods One hundred and thirty-four climacteric males with ED were divided into the observation group and control group,67 cases in each group.The observation group was given the therapy of eurycoma longifolia and the control group was treated with testosterone undecanoate.After 3-month treatment,the scores of EHS,SHIM,AMS,EDITS,changes of serum to-tal testosterone(TT),free testesterone(FT),luteinizing hormone(LH),follicle stimulating hormone(FSH)and sex hormone-bind-ing globulin(SHGB)and complication occurrence rate were compared between the two groups.Results After 3-month treatment, the scores of EHS,SHIM,AMS and EDITS,and serum TT and FT levels in the two groups were significantly improved(P<0.05),moreover the results in the observation group were better than those in the control group(P<0.05);serum LH and FSH in the observation group had no obvious changes compared with before treatment(P>0.05),while which in the control group were significantly decreased compared with before treatment(P<0.05);serum SHGB level in the observation group was decreased com-pared with before treatment(P<0.05),while which in the control group was increased compared with before treatment(P<0.05);the EDITS score in the observation group was higher than that in the control group(P<0.01);the complication incidence rate in the observation group was 2.29 %,which was significantly lower than 16.41% in the control group(P<0.05).Conclusion Eury-coma longifolia can significantly improve sexuality and sexual function in climacteric males.
10.Intranasal Oxytocin Increases Perceptual Salienceof Faces in the Absence of Awareness
Shao-Wei XUE ; Hua-Bo WU ; Lanhua ZHANG ; De-Xuan ZHANG
Psychiatry Investigation 2020;17(4):292-298
Objective:
The neuropeptide oxytocin has been found to improve human social cognition and promote prosocial behavior. However, itis still unclear about the mechanisms underlying these effects of oxytocin on neural processes, such as visual perception and awareness.Especially, it is still unclear whether oxytocin influences perceptual salience of social stimuli in the absence of awareness.
Methods:
In a randomized double-blind, placebo-controlled trial we applied an interocular suppression paradigm and eye tracking
methods:
to investigate the influence of intranasally administered oxytocin on perceptual salience of social stimuli. Suppression times andpupillometric data were measured during subjects being presented with gradually introduced pictures of social stimuli (neutral expressionfaces) or nonsocial stimuli (grayscale watch pictures) that were suppressed and invisible in 10 men who were administered 24 IU oxytocinand 10 men who were administered a placebo.
Results:
The results demonstrated that the oxytocin group perceived social stimuli more quickly accompanied by subsequent larger increasingpupil diameter than nonsocial stimuli, indicating an increased unconscious salience of social stimuli.
Conclusion
These findings provided new insights into oxytocin’s modulatory role to social information processing, suggesting that oxytocinmight enhance attentional bias to social stimuli even after removal of awareness. Psychiatry Investig 2020;17(4):292-298