Surface plasmon resonance(SPR) is an optical phenomenon arises from mass changes on sensors based on in-teraction between substances ,which could monitor the interaction between biomolecules quickly and accurately .It has the ad-vantage of label-free ,high specificity ,high accuracy ,real-time and on-line monitoring ,which has attracted comprehensive at-tention in recent years .SPR biosensors could be applied in drug discovery ,clinical diagnosis ,food safety ,environment monito-ring and proteomics .In this manuscript ,the application of SPR biosensors in food safety ,environment monitor and biomedical analysis have been reviewed ,which could provide reference to related research .
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