As a kind of initiative maintenance,preventive maintenance mainly aims at prolonging service life of medical equipment,extending their fault-free time and lowering the whole life expense.It is an important measure that preventive maintenance be strengthened in keeping the safe and highly efficient operation of medial equipment for maximum social and economic benefit.The work flow design of medical equipment preventive maintenance is introduced including the plan,execution and check,giving guidance to medical equipment preventive maintenance.[Chinese Medical Equipment Journal,2008,29(2):71,73]

Brain injury is a significant cause leading to death of neonates with a considerable variety of complications.Up to now researches have found the neuroprotective actions of erythropoietin (EPO) originally identified as erythropoiesis on neonatal brain injury.EPO has been reported to induce a broad effect in the brain directed to protect and repair neurons damage which are likely to contribute to the improvement in long-term neurological functional outcomes.EPO may provide a new approach for promoting survival and growth in nerve cells and hold great promise for the future treatments of neonatal brain injury.EPO and EPO receptor distribute in defferent parts of brain in fetus and newborns.A fundamental mechanism of EPO-induced neuroprotection is its ability to inhibit apoptosis that EPO and EPO receptor have been shown to modulate three cellular signal transduction pathways.The other neuroprotection mechanisms of EPO-induced include anti-infammatory,neurotrophy,anti-oxidation,angiogenesis,promoting neurogenesis and anti-epilepsy.

AIM:To discuss the relationship between molecular biology and modernization of Chinese materia medica(CMM)with the hope that molecular biology may play an important role in promoting modernization of CMM.METHODS:The currentsituation and progress in using the theoy and technique of molecular biology in the research fields of CMM were reviewed. RESULTS:The technique of modern molecular biology, such as, the identification of crude drugs, the culture and production of medicinal plants,the screening of effective components from CMM and the analysis of the mechanisms of the action of CMM, has been applied in the research work of CMM.CONCLUSION: The extensive use of the technique of molecular biology in the research of CMM will greatly promote the modernization of it.The research workers and policy makers in these fields must pay close attention to them.

Objective: To investigate the level of cell adhesion molecule E-selectin in colorectal neoplasm and its relations with metastasis in the blood line. Methods:E-selectin expression in colorectal carcinoma and normal colorectal tissue were detected with immunohisochemical technique. The change of shift ability of human colorectal neoplasm cell line was analyzed. Results: The expressing rate of E-selectin was 57.5%,obviously higher than 6.67% in the normal colorectal tissue(P

Congenital heart disease(CHD) is a series of birth defect that can actually or potentially impact heart function , occurring 4‰～ 12‰ of live birth. Atrioventricular septal defect (AVSD) is a frequently CHD affecting the atrioventricular valves and septa. AVSD refers to a clinical spectrum of defects ranging from a complete AVSD to cleft mitral valve. AVSD occurs most frequently in Trisomy 21 syndrome. Research shows that the development defect of endocardial cushion caused by heredity and environment during different period of heart development leads to all kinds of AVSD. CRELD1 is the first identified gene associated with morbidity of AVSD.The research on this gene has important significance to find out the pathogenesis of AVSD and provide better prevention and cure methods.

Objective:To determine the expression of complement regulatory proteins(CRPs) C_1-INH,MCP(CD46) in the nasal mucosa of allergic rhinitis rats and to study the role of CRPs in the pathogenesis of allergic rhinitis.Methods: Nine healthy SD rats were sensitized and intranasally challenged with ovalbumin and Al(OH)_3(as supplement) to establish allergic rhinitis models and another 9 SD rats treated with saline were taken as control.The nasal mucosa in respiratory area of both groups was obtained.Then Western blotting was performed to investigate the expression levels of C_1-INH and CD46.Results: Western blotting showed that both C_1-INH and CD46 had been detected in rat nasal mucosa.Expression level of CD46 in the nasal mucosa of allergic rhinitis was significantly higher than that in control rats(P

In order to make use of gerbils as a kind of experimental animal in Kunming, the Mongolian Gerbilis were indroduced into laboratory of KMC from Beijing for two years, and performed the management and breeding. This paper summarized the authoris experieuce of mating, breeding. diet regimen, house cleaning, care of the pregnant and newborn. The data of body weight measured in relation to the age were also presented.

[Objective]To compare the contents of heavy metals in 6 types of Niuhuang jiedu tables.[Methods]The content of heavy metals in 6 types of Niuhuang jiedu tables before or after passed through metabolically man-made stomach liquid was detected by inductively coupled plasma atomic eminssion spectrometry(ICP-AES).[Results]These contents of heavy metals in 6 drugs were more than the order in chinese standards.But the contents of acid-soluble heavy metals were much less than or partially accorded with total heavy metals in the same batch of sample.[Conclusion]The content of acid-soluble heavy metals may be taken as one of the items of quality control for the Niuhuang jiedu tablets and traditional Chinese medicine patent prescription.

Objective]To summarize the clinical experience of Zhang Yu-zhu to treat Bi-Syndrome. [Methods] Summarized the academic view and clinical experience of Zhang yu-zhu to treat Bi-syndrome,including etiology and pathogenesis,therapeutic principle and the formulas of Zhang Yu-zhu. Summarize the compatibility and modified formulas,and proven cases attached. [Result] The cause of Bi-syndrome was divided into two types: one was external pathogen,which was caused by wind,cold and wet. The other was internal pathogen,including spleen and kidney deficiency,the unbalance of Ying qi and Wei qi and insecurity of the interstices. When diagnosing and treating Bi-syndrome ,he emphasized combining Chinese and western medicine and syndrome differentiation. [Conclusion]Zhang Yu-zhu's treatment of Bi-syndrome has evident effect.

Objective:To investigate the clinical efficacy between one and two hemoperfusion in treatment of chronic hepatitis with hyperbilirubinemia.Methods:The clinical data of 68 chronic hepatitis patients with hyperbilirubinemia were reviewed restropectively.27 patients were treated with one hemoperfusion(HP1)and 41 patients were treated with two hemoperfusion(HP2).The liver function,prothrombin time activity,biochemical indicators before and after hemoperfusion in the two groups were compared and analyzed.Results:After two hemoperfusion treatment.,Compared with HP1,the levels of bilirubin and transaminase were decreased significantly(P0.05).Conclusions:Two hemoperfusion treatment can more effectively make bilirubin and transaminase removed from patients of chronic hepatitis with hyperbilirubinemia,so two hemoperfusion was safe and effective treatment for patients with hyperbilirubinemia.