OBJECTIVE:To optimize the extract technology of Qinggan lidan capsule.METHODS:The extraction technology of Qinggan lidan capsule was optimized by orthogonal experiment with the content of anthraquinone and ethanol extract, the extracting amount of chloroform and n-butyl alcohol as index and with extracting amount of ethanol, extracting frequency and extracting time as factors. RESULTS:The optimal extraction technology was adding 8-fold, extracting for 2 times and for 1.5 h. CONCLUSION: The extraction technology is appropriate and feasible and it provide theoretic basis for the production of Qinggan lidan capsule.