1.Multifetal pregnancy reduction (MFPR) after infertility treatment
Journal of Medical and Pharmaceutical Information 1998;(1):27-33
From January 2001 to September 2001, MFPR were performed for 26 multifetal pregnancies after infertility treatment. Transvaginal selective embryo aspiration was performed at the ninth week of gestation, without KCl injected in the vicinity of the fetal heart. The mean number of viable embryos before and after reduction was 3.4 and 2.1. There were no complications recorded after the procedure such as vaginal bleeding, amniotic leakage and infection. The rate of miscarriage before 24 weeks was 7.1%. The mean gestation length and the mean birth weight were 36.22.8 weeks and 2360.0349.4g for the twins, respectively, and 30.67.6 weeks and 2066.7177.9 g for the triplets. Results from this study were comparable to the other studies worldwide. Preliminary data from this study showed that early transvaginal embryo aspiration without using KCl is a safe, effective method to improve obstetric outcome of multifetal pregnancies after infertility treatment.
Pregnancy Reduction, Multifetal
;
Infertility
;
therapy
2.Intra cytoplasmic sperm injection using surgically recovered epididymal sperm for treating obstructive azoospermic men
Journal of Medical and Pharmaceutical Information 2003;0(6):31-34
From February to December 2002, 67 obstructive azoospermic cycles was undergone. Epididymal sperm were recovered and embryo replacement were performed in all cases. Clinical pregnancy rate was 39.1%. Extra sperm and extra good embryos were cryopreserved for future use. Two cases continue to the second procedure after fail in the first time 3 cases couldn’t have pregnancy use cryopreserved embryos. No case have 3 foetus up ward. The rate with one foetus is 70.4%, two foetus is 29.6%
Sperm Injections, Intracytoplasmic
;
Pregnancy
;
Spermatozoa
;
Therapeutics
3.Rectally administered misoprostol in the prevention of pospartum hemorrhage due to uterine inertia
Ho Chi Minh city Medical Association 2003;8(3):130-132
Hemorrhage;Postpartum Period; Uterine Inertia; prevention & control;
777 postpartum women were studied at Tu Du Obstetric and Gynecology Hospital, HCM city. Rectal misoprostol of 400mg was well tolerated and effective to reduce hemorrhage amount and to shorten the 3rd phase of labor just after the delivery. The procedure is simple with low cost, easy to use in remote areas of the country contributing in lowering obstetric accidents and mortality.
Hemorrhage
;
Postpartum Period
;
Uterine Inertia
;
prevention & control
4.Diagnose and prevent relapse in childen with rheumatic heart diseasewho treated in National Hospital for paediatrics.\r\n', u'\r\n', u'
Journal of Medical Research 2007;55(6):41-45
Background:Rheumatic heart disease is an acquired heart disease which often seen in the year of 90's. Nowaday, due to the development of health care system, population benefit much of knowledge to prevent this disease, the rate of prevenlence reduce significant. Objectives:This study aims to diagnose and prevent relapse in childen with rheumatic heart diseasewho treated in National Hospital for Pediatrict. Subjects and method:A retrospective study was conducted on 236 children with rheumatic heart diseaseor cardiac valve diseasewho admitted at Cardiology department of the National Hospital for Pediatrics from 1st January 2001 to December 31, 2005. Results:29.7% (70/236) were hospitalized for rheumatic valve disease. Among 166 hospitalized children due to continuous rheumatic heart disease, the result showed that: The types of carditis and arthritis were the most frequent and at least 22.9% (38/166) of children had definitive permanent valve lesions . 65.7% (44/76 responses) children received proper prevention. Some of them were not monitored at the center of prevention. The greater part of the rest had no knowledge of this disease. Conclusion:Rheumatic heart disease reduced but the prevalence of heart valve complication increased.\r\n", u'\r\n', u'
Rheumatic Heart Disease/ diagnosis
;
therapy
;
Infant
5.The impact of hyperandrogenism on the outcomes of ovulation induction using gonadotropin and intrauterine insemination in women with polycystic ovary syndrome
Vu Ngoc Anh HO ; Toan Duong PHAM ; Nam Thanh NGUYEN ; Hieu Le Trung HOANG ; Tuong Manh HO ; Lan Ngoc VUONG
Clinical and Experimental Reproductive Medicine 2022;49(2):127-134
Objective:
This study aimed to investigate the impact of hyperandrogenism (HA) on the outcomes of ovulation induction (OI) using gonadotropin and intrauterine insemination (IUI) in patients with polycystic ovary syndrome (PCOS).
Methods:
This was a retrospective cohort study including 415 patients undergoing OI using gonadotropin and IUI treatment between January 2018 and December 2020 at a single infertility center. Baseline characteristics, clinical and laboratory parameters, and pregnancy outcomes were investigated.
Results:
Among the study population, there were 105 hyperandrogenic (25.3%) and 310 non-hyperandrogenic patients (74.7%). The live birth rate was lower in the HA group than in the non-HA group, but this difference did not reach statistical significance due to the limited sample size (14.3% vs. 21.0%, relative risk=0.68; 95% CI, 0.41–1.14, p=0.153). No predictive factors for live birth were identified through logistic regression analysis.
Conclusion
HA did not negatively affect the outcomes of OI using gonadotropin and IUI cycles in Vietnamese women with PCOS. The result may not be applicable elsewhere due to the large variation in the characteristics of women with PCOS across races and populations.
6.Predictors of twin pregnancy in in vitro fertilization with intracytoplasmic sperm injection cycles with day 3 double embryo transfer
Duy Le NGUYEN ; Hieu Le-Trung HOANG ; Vu Ngoc-Anh HO ; Toan Duong PHAM ; Nam Thanh NGUYEN ; Van Thi-Thu TRAN ; Tuong Manh HO ; Lan Ngoc VUONG
Clinical and Experimental Reproductive Medicine 2024;51(1):69-74
Objective:
The purpose of this study was to identify factors associated with twin pregnancy following day 3 double embryo transfer (DET).
Methods:
This retrospective cohort study incorporated data from 16,972 day 3 DET cycles. The participants were women aged between 18 and 45 years who underwent in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) at My Duc Assisted Reproduction Technique Unit (IVFMD), My Duc Hospital, located in Ho Chi Minh City, Vietnam.
Results:
Of the 16,972 day 3 DET cycles investigated, 8,812 (51.9%) resulted in pregnancy. Of these, 6,108 cycles led to clinical pregnancy, with 1,543 (25.3% of clinical pregnancies) being twin pregnancies. Factors associated with twin pregnancy included age under 35 years (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.32 to 1.71; p<0.001) and cycles involving the transfer of at least one grade I embryo. Relative to the transfer of two grade III embryos, the risk of twin pregnancy was significantly elevated following the transfer of two grade I embryos (OR, 1.40; 95% CI, 1.16 to 1.69; p<0.001) or a combination of one grade I and one grade II embryo (OR, 1.27; 95% CI, 1.05 to 1.55; p=0.001).
Conclusion
By analyzing a large number of IVF/ICSI cycles, we identified several predictors of twin pregnancy. These findings can assist medical professionals in tailoring treatment strategies for couples with infertility.