1.Forensic practice in sudden infant death syndrome
Chinese Journal of Forensic Medicine 1987;0(03):-
Sudden infant death syndrome(SIDS) has become a highlighted topic in forensic medicine and pediatrics since it was firstly defined in 1969.As some great improvements were preceded in many aspects,people know more about its features,summarization,classification and related genes.There are many reports from developed areas such as North America,Europe,Australia,Japan etc.,but few from China.This review introduces SIDS's development history,new scientific findings and discusses the feasibility of further SIDS studies and the key points in forensic practice under the influence of San Diego definition of SIDS.
2.Exploration on improving the teaching quality of oncological probation
Chinese Journal of Medical Education Research 2003;0(03):-
This article analyses the characteristics and current situation in oncology teaching,and studies the goals,task and methods on oncological probation.
3.Information Therapy Research Review
Journal of Medical Informatics 2017;38(2):48-51,68
The paper introduces the origin and definition of information therapy,analyzes the study object of information therapy including information prescription,users,healthcare opportunity and so on,describes the efficacy and function in healthcare of information therapy on relationship establishment,cost effect,patient education,patient safety,health realization,etc.,points out the future development direction of information therapy.
5.Intervention of Ginkgo biloba extract on renal hemodynamics and its clinical protective mechanism
Hongfeng HUANG ; Qian LIANG ; Lan LAN ; Jianyong WU ; Jianghua CHEN
Chinese Journal of Organ Transplantation 2015;36(11):652-656
Objective To observe the effect and safety of Ginkgo biloba extract (EGb) in patients with chronic allograft nephropathy (CAN),and to study the clinical protective mechanism of EGb.Method A prospective,non-randomized,controlled study was conducted on 103 cases of CAN from March 2013 to March 2015.All patients were divided into experimental group (group A,53 cases) and control group (group B,50 cases).The group A was treated with EGb.Patients were followed up for at least 6 months.Before and after treatment,the changes in renal hemodynamic parameters were observed.The biochemical parameters were also observed,including 24-h urinary protein,urinary albumin,serum creatinine (Scr),triglyceride (TG),total cholesterol (TC),estimated glomerular filtration rate (eGFR),platelet count (PLT),fibrinogen (FIB),D-dimer (DD),activated partial thromboplastin time (APTT).The clinical efficacy and safety were analyzed.Result (1) Therewere no significant differences in clinical and biochemical parameters between the two groups before treatment (P>0.05).(2) After treatment,the systolic peak flow velocity (Vmax) of segmental artery and arcuate artery in the experimental group was significantly higher than in the control group,and the resistance index (RI) in the experimental group was significantly lower than that in the control group,P<0.05.(3) In both two groups,the 24-h urinary protein,urinaryalbumin,TG,TC and Scr were decreased after treatment (P<0.05),and eGFR was elevated (P<0.05).Moreover,the changes in 24-h urinary protein and urinary albumin in the experimental group were more significant than the control group after treatment (P<0.05).(3) PLT,FIB and DD in experimental group were significantly decreased after treatment,and APTT was increased significantly (P<0.05).PLT,FIB,DD and APTT had significant change after treatment in the experimental group as compared with control group.(4) There were no significant differences in adverse reactions between two groups (x2 =0.047,P =0.828).Conclusion The therapy of EGb in patients with CAN could reduce urinary protein and improve hypercoagulable state,and had few adverse reaction with good security.
7.Nursing research in the sputum culture specimen monitoring of patients with pulmonary infection
Huafei CHEN ; Liang XIE ; Lan CHEN
Chinese Journal of Practical Nursing 2008;24(18):9-11
Objective We discussed the nursing management measures to improve the qualified rate of sputum culture specimen of patients with pulmonary infection. Methods We monitored the qualified rate of sputum culture specimen, positive rate, pathogen distribution and drug resistance for patients with pulmonary infection in our hospital. Data collected from January 2007 to February 2008 were set as the test group. Data collected from January 2005 to December 2006 were set as the control group. The monitoring effect was compared in the two groups. Results The qualified rate of sputum culture specimen and the distribution of bacteria and fungus in the test group were different from those of the control group (P<0.01). Conclusions To strengthen the quality control of sputum culture specimen, comprehensively improve the cognition of nurses to the significance of qualified rate of sputum culture specimen and the techique of collecting sputum culture specimen could ensure the qualified rate of sputum culture specimen.
8.The comparison of clinical efficacy of specific immune therapy for one year and two years of allergic rhinitis
Liang ZHANG ; Ning LAN ; Hong XU
Journal of Medical Postgraduates 2014;(10):1073-1075
Objective In recent years , SIT has gradually become the main way for the treatment of allergic rhinitis .To con-trast the clinical efficacy of specific immune therapy for one year and two years of allergic rhinitis and discuss the appropriate mainte -nance treatment time of subcutaneous immunotherapy with Dermatophagoides pteronyssinus . Methods Ninety-eight patients with al-lergic rhinitis to Dermatophagoides pteronyssinus were allocated to receive either treatment for one year (A group, n=46) or treatment for two years(B group, n=52).Nasal symptoms and medication scores of two groups were assessed to evaluate the clinical efficacy af -ter treatment respectively , and evaluate the quality of life of patients . Results There was no statistical significance in nasal symptom and medication scores between the two groups after one year treatment (7.00 ±1.08 vs 6.63 ±0.79, 1.50 ±0.51 vs 0.41 ±0.42, P>0.05).The quality of life in patients with decreased , but lack of statistical significance (345.00 ±31.89 vs 344.42 ±32.26, P>0.05).It presented statistical significance in nasal symptom and medication scores between the two groups after two years treatment (6.20 ±0.78 vs 4.29 ±0.64, 0.53 ±0.43 vs 0.21 ±0.34, P<0.05).The quality of life between patients also presented statistical significance (P<0.05). Conclusion Compared with A group, B group can significantly alleviate the symptoms of allergic rhinitis , so we think the optimal maintenance treatment time of specific immunotherapy for allergic rhinitis should be at least 2 years.
9.Preventive Effect of Mannatide on Relapsing of Idiopathic Thrombocytoperlic Purura
de-zheng, LAN ; xian-liang, SONG
Journal of Applied Clinical Pediatrics 2004;0(09):-
Objective To observe the preventive effect of mannatide on infection and relapse of idiopathic thrombocytopenic purura(ITP).Methods One hundred and twenty children with ITP were randomly divided into mannatide treatment group and prednisone control group.Control group venous dexamethasone of 3 d;then treated by prednisone.Treatment group added mannatide tablets for 1 month.The rates of remission clinical blood,platelet,control time,complicated infection and relapse rates were observed.The levels of plasma immunoglobulin(Ig)G,IgA,IgM were determined before and after mannatide treatment.Results The rate of clinical blood,platelet,control time,infection time was not different in 2 groups.The rates of infection complicated and relapse were all significant lower than that in control group.The plasma IgG,IgA significantly increased than that in control group.The plasma IgM had no significant difference.Conclusion Vaccine therapy can be helpful in protecting and decreasing infection,diminishing relapse of children with ITP,and improve the level of IgG,IgA,and thus improve their immune function.