1.Detection of Epstein-Barr virus DNA in nasopharyngeal cancer by polymerase chain reaction.
Jang Su SUH ; Tae Yoon LEE ; Seong Ho BAE ; Sung Kwang KIM ; Weon Hee CHOI ; Kyung Lak SON
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):185-192
No abstract available.
DNA*
;
Herpesvirus 4, Human*
;
Nasopharyngeal Neoplasms*
;
Polymerase Chain Reaction*
2.Clinical Features of Patients who Received Liver Transplantation in China.
Bum Su BAEK ; Dong Lak CHOI ; Young Seok HAN ; Mi Kyung KIM
The Journal of the Korean Society for Transplantation 2006;20(2):248-252
Purpose: Liver transplantation (LT) is now considered as a standard treatment modality for patients with end-stage liver disease. The number of patients waiting for liver graft is continuosly increasing as there is a shortage of brain-dead donors, living donor liver transplantation has been regarded as an alternative. Furthermore, China where donors are more readily available is quickly growing as a place to travel for transplantation. Methods: Twenty-eight patients who were on follow up after LT in China were enrolled. Pre-transplantation state of donors and recipients, surgical problems at the time of arrival, and complications that were detected on follow up were evaluated and analyzed. Results: All patients did not have the information of donors and knowledge of their transplanted state. All patients were received conventional deceased donor LT and the type of duct anastomosis was duct to duct technique. Hepatitis B virus (HBV) recurrence was detected in two patients, various prophylaxes were used, and inappropriate modalities were detected. Biliary complications occurred in 6 patients, who were treated with percutanous or endoscopic method. There were 5 patients mortalities: 3 patient-hepatocellular carcinoma recurrence, 1- post-transplant lymphoproliferative disease, 1-cardiac arrhythmia after retransplantation. Conclusion: The shortage of deceased donor resulted in more and more travel to China for liver transplantation. However, we have problems to solve: lack of donor information, insufficient techniques of transplantation, inappropriate post-transplantation care, and lack of education for immunosuppression and prophylaxis of HBV recurrence. In addition, the efforts to increase donations should be continued.
Arrhythmias, Cardiac
;
China*
;
Education
;
Follow-Up Studies
;
Hepatitis B virus
;
Humans
;
Immunosuppression
;
Liver Diseases
;
Liver Transplantation*
;
Liver*
;
Living Donors
;
Mortality
;
Recurrence
;
Tissue Donors
;
Transplants
3.Establishment of Diatom Profile for Improving Reliability of Diagnosis of Drowning - Centered on the Main Drowning Sites of Han River.
Kyung Lak LEE ; Jae Sin CHOI ; Hyun Moo KANG ; Young Joo KIM ; Joon Ho LEE ; Sol Yi PARK ; Han Soon KIM
Korean Journal of Legal Medicine 2011;35(2):120-129
Diatomology has provided important evidences for diagnosis of drowning in forensic practice. However, conflicting opinions about the reliability of diatom test still exist. As a part of efforts to end this controversy, it is very important to secure the diatom profile in the water sample of drowning site. Our results obtained in this study show the characteristics of temporal and spatial distribution of diatom collected from the main drowning sites of Han river in Korea. During spring, 111 taxa (98 species and 13 varieties) were identified from 31 genera, and 87 taxa (77 species and 10 varieties) were identified from 22 genera during summer. At the level of genus Achnanthes, Cyclotella, Cymbella, Fragilaria, Navicula, Nitzschia, and Stephanodiscus represented the highest numbers, and were the most widely occurred during two seasons. The centric diatoms, Stephanodiscus hantzschii f. tenuis and Cyclotella atomus were typical of spring and summer, respectively, and identified as dominant indicator species. The commonly occurred species, including dominant species in the seasonal cluster analysis influenced the formation of site - specific groups. As a result, our results will be able to be used not only as the comparison data of diatom found in the drowning victim's tissue but also a reference data to rule out the possibility of contamination.
Diatoms
;
Drowning
;
Korea
;
Rivers
;
Seasons
;
Water
4.Comparison of Clinical Finding and Mortality Rate in Neonatal Gastrointestinal Perforation due to Necrotizing Enterocolitis and Other Causes.
Kyung Ji KANG ; Ji Hyeun SONG ; Chun Soo KIM ; Sang Lak LEE ; Soon Ok CHOI ; Woo Hyun PARK
Korean Journal of Perinatology 2011;22(2):108-113
PURPOSE: This study was conducted to compare the clinical features and outcome of neonatal gastrointestinal perforation due to necrotizing enterocolitis (NEC) and other etiologic diseases (non-NEC). METHODS: The medical records of neonates, admitted to the neonatal intensive care unit of Dongsan Medical Center for gastrointestinal perforation between January 1999 and December 2009, were reviewed retrospectively. The admission records for clinical findings and mortality were reviewed and statistically analyzed for both groups. RESULTS: Among 28 neonates, NEC group was 35.7% and the other group (intestinal atresia, malrotation, meconium peritonitis, etc) was 64.3%. The mean gestational age was significantly shorter (32.8+/-4.6 weeks vs. 36.8+/-2.7 weeks, P=0.028) and the mean diagnostic day was significantly later (16.3+/-9.7 days vs. 2.2+/-1.8 days, P=0.001) in the NEC group than that of the non-NEC group. The mortality rate was markedly higher in the NEC group (50%) than that of the non-NEC group (5.6%)(P=0.013). By simple logistic regression analysis, gestational age (OR 0.69, 95% CI: 0.51-0.95, P=0.022) and NEC (OR 17.00, 95% CI: 1.60-181.36, P=0.019) were the significant risk factors to increase the mortality rate. Multiple logistic regression analysis showed NEC (OR 7.70, 95% CI: 0.55-108.06, P=0.130) and gestational age (OR 0.79, 95% CI: 0.58-1.09, P=0.151) were not the significant independent risk factors. CONCLUSIONS: This study found that gestational age was shorter and mortality rate was higher in the NEC group than the non-NEC group. However, after multiple logistic regression analysis, NEC or lower gestational age itself did not increase the mortality rate significantly.
Enterocolitis, Necrotizing
;
Gestational Age
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Humans
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Logistic Models
;
Meconium
;
Medical Records
;
Peritonitis
;
Retrospective Studies
;
Risk Factors
5.Identification of African swine fever virus genomic DNAs in wild boar habitats within outbreak regions in South Korea
Kyung-Lak LEE ; Yongjun CHOI ; Jongchan YOO ; Jusun HWANG ; Hyun-Gi JEONG ; Weon-Hwa JHEONG ; Seon-Hee KIM
Journal of Veterinary Science 2021;22(2):e28-
An African swine fever (ASF) outbreak in wild boars was first reported on October 2, 2019, in South Korea. Since then, additional cases were reported in South Korea's border areas. We here report the identification of ASF virus (ASFV) DNAs from two out of eight environmental abiotic matter samples collected from areas where ASF-positive wild boar carcasses were found. Comparative genomic investigations suggested that the contaminating ASFV DNAs originated from the wild boar whose carcass had been found near the positive sample sites.This is the first report on the identification of ASF viral material in wild boar habitats.
6.Identification of African swine fever virus genomic DNAs in wild boar habitats within outbreak regions in South Korea
Kyung-Lak LEE ; Yongjun CHOI ; Jongchan YOO ; Jusun HWANG ; Hyun-Gi JEONG ; Weon-Hwa JHEONG ; Seon-Hee KIM
Journal of Veterinary Science 2021;22(2):e28-
An African swine fever (ASF) outbreak in wild boars was first reported on October 2, 2019, in South Korea. Since then, additional cases were reported in South Korea's border areas. We here report the identification of ASF virus (ASFV) DNAs from two out of eight environmental abiotic matter samples collected from areas where ASF-positive wild boar carcasses were found. Comparative genomic investigations suggested that the contaminating ASFV DNAs originated from the wild boar whose carcass had been found near the positive sample sites.This is the first report on the identification of ASF viral material in wild boar habitats.
7.Differences of Personality Characteristics According to the Suicide Symptoms in Patients with Depression
Yong Lak CHOI ; Mi Ae OH ; Sang Min LEE ; Jong Woo KIM ; Won Sub KANG
Korean Journal of Psychosomatic Medicine 2019;27(2):164-172
OBJECTIVES:
The purpose of this study was to examine personality traits associated with suicidal symptoms (with history of suicide attempt or suicidal idea) in depressed patients.
METHODS:
A sample 186 patients diagnosed with major depressive disorder was divided into two groups : suicidal group (with history of suicide attempt or suicidal idea, n=70) and non-suicidal group (without history of suicide attempt or suicidal idea, n=116). NEO Personality Assessment System were used to evaluate personality trait.
RESULTS:
Neuroticism was high in suicidal group (p=0.041). In multivariate logistic regression, Neuroticism was also a significant influence on suicidal symptoms (Odds Ratio=1.04, 95% Confidence Interval 1.01–1.07, p=0.0145).
CONCLUSIONS
High Neuroticism is a useful information to identify individuals at high risk of suicide in depressive patients.
8.The Correlation Between Defense Mechanism and Posttraumatic Stress Disorder in Burn Patients
Dowon LEE ; Yanghwan CHOI ; Jong Dae KIM ; Kyung-Lak SON ; Woo Young IM ; Jin Yong JUN
Korean Journal of Psychosomatic Medicine 2021;29(2):191-198
Objectives:
:This study was designed to investigate the correlation between defense mechanism and posttraumatic stress disorder in burn patients.
Methods:
:We recruit 40 burn patients and we evaluate sociodemographic characteristics, characteristics related to burn, korean version of Impact of Event Scale-Revised (IES-R), Korean Version of Center for epidemiologic studies depression scale (CES-D) and Ewha Defense Mechanisms Test (EDMT). Multiple regression analysis was performed to evaluate the correlation between EDMT score and IES-R score.
Results:
:Factor 2 of EDMT which consists of Ego-expansion subjects was significantly correlate with IER-S score. In factor 2, Controlling (β=-0.299, p<0.05), Sublimation (β=-0.276, p<0.05) is significantly correlate with IER-S score.
Conclusions
:Some subjects of defense mechanism was significantly correlate with IES-R score. it might behelpful to understand defense mechanism for the posttraumatic stress disorder in burn patients.
9.Endoscopic Treatment of a Symptomatic Ileal Lipoma with Recurrent Ileocolic Intussusceptions by Using Cap-Assisted Colonoscopy.
Eun Sung LEE ; Kang Nyeong LEE ; Kyung Soo CHOI ; Hang Lak LEE ; Dae Won JUN ; Oh Young LEE ; Byung Chul YOON ; Ho Soon CHOI
Clinical Endoscopy 2013;46(4):414-417
A 73-year-old woman presented with intermittent abdominal pain and weight loss of 15 kg for 2 years. Colonoscopy revealed an erythematous polypoid tumor with a long and wide stalk in the cecum, but with air inflation, it abruptly went away through the ileocecal valve (ICV). An abdominal computed tomography showed a well-demarcated pedunculated subepithelial mass of 2.6x2.7 cm size with fat attenuation in the terminal ileum. It was an intussusceptum of the ileal lipoma through the ICV. This ileal lipoma was causing her symptoms because repeated ileocolic intussusceptions resulted in intermittent intestinal obstructions. In order to avoid surgical sequelae of ileal resection, snare polypectomy using cap-assisted colonoscopy technique was performed within the ileum without complications. The histopathology report confirmed it as a subepithelial lipoma. After endoscopic resection of the ileal lipoma, the patient has been free of symptoms and was restored to the original weight.
Abdominal Pain
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Cecum
;
Colonoscopy
;
Female
;
Humans
;
Ileocecal Valve
;
Ileum
;
Inflation, Economic
;
Intestinal Obstruction
;
Intussusception
;
Lipoma
;
SNARE Proteins
;
Weight Loss
10.Comparison of Clinical Findings of Gastric Perforation between Preterm and Term Neonates.
Eun Ha KIM ; Kyung Ji KANG ; Chun Soo KIM ; Sang Lak LEE ; Eunyoung JUNG ; Soon Ok CHOI ; Woo Hyun PARK
Korean Journal of Perinatology 2013;24(2):89-94
PURPOSE: The purpose of this study was to compare the clinical findings and mortality of gastric perforation between preterm and term infants. METHODS: The medical records of neonates, admitted to the neonatal intensive care unit of Dongsan Medical Center for gastric perforation between July 1992 and June 2012, were reviewed retrospectively. The admission records of clinical findings and mortality were reviewed and statistically analyzed between preterm and term infants. RESULTS: Nine infants were diagnosed with neonatal gastric perforation. Of the nine infants, the number of term infants was five and the number of male was eight. Of the four infants diagnosed with spontaneous gastric perforation, the number of preterm and term infants was three and one respectively. The anatomical location of perforation was greater curvature in all four preterm infants. However, various sites such as greater curvature (three infants) and antrum (two infants) were observed in five term infants. Mortality rate was tended to be lower in preterm infants compared to term infants, without statistical significance (25.0% vs. 40.0%, P>0.1). There was no mortality in four infants diagnosed with spontaneous gastric perforation. However, two infants diagnosed with necrotizing enterocolitis (NEC) all died. CONCLUSION: There was no significant difference in clinical findings and mortality of gastric perforation between preterm and term infants. The prognosis of spontaneous gastric perforation was good, however, mortality rate was tended to be higher in NEC than other causes (P=0.083).
Enterocolitis, Necrotizing
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Intensive Care, Neonatal
;
Male
;
Medical Records
;
Prognosis
;
Retrospective Studies