1.Experimental study of survival time and mortality in war injuries complicated by seawater immersion
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
Objective To evaluate the mortality and survival time of war injuries, followed by seawater immersion. Methods Animal models of injuries including open chest injury, open abdominal injury, burn, hemorrhagic shock, were reproduced. The animals were divided into two groups: control group consisting simple injury without seawater immersion, and seawater immersion group consisting similar injuries followed by seawater immersion. The survival time of animals of the two groups were recorded. Results The mean survival time of the animals with open chest injury and open abdominal injury followed by seawater immersion was 45 minutes and 162 minutes, respectively. The mortality of 30% Ⅱ degree burn was 50% after seawater immersion for 4 hours, while it was 6% without seawater immersion. The mortality of moderate hemorrhagic shock with four-hour with seawater immersion was 90%, while all the animals survived without seawater immersion. Conclusions The experimental study showed that the mortality rate was significantly raised and the survival time significantly shortened when open wounds were exposed to seawater for a certain period of time. Hypertonicity of the seawater with high sodium content, and low temperature of seawater might play important roles in producing various pathophysiological changes which contributed to early death of the animals.
2.Diagnosis and treatment of contrecoup contusion and laceration in frontal lobe
Yu CHEN ; Runlong LAI ; Yong LI
Chinese Journal of Primary Medicine and Pharmacy 2010;17(14):1915-1916
Objective To discuss the clinical characteristics and therapeutic strategy of contrecoup contusion and laceration in frontal lobe. Methods 48 cases with contrecoup contusion and laceration in frontal lobe were analysed retrospectively with their imaging feature. Results In accordance with the GOS,36 cases survived well, 8 suffered from moderate disability. One keept in persistent vegetative state and one was dead. Conclusion Contrecoup contusion and laceration in frontal lobe merged with occipital extradural hematoma and diffuse brain swelling. Early diagnosis and treatment for the delayed occipital extradural hematoma, and standard large trauma craniotomy in treatment of heavy contrecoup contusion and laceration with diffuse brain swelling in frontal lobe were the key measures to improve the rate of success rescue.
4.Treatment on bone nonunion by extracorporeal shock wave combine hyperbaric oxygen
Shaolin YU ; Hongyu LI ; Wenbing LAI ; Yong YANG ; Min CAI
Chongqing Medicine 2015;(28):3908-3910,3914
Objective To explore the effect and action principle of extracorpoporeal shock wave(ESW) combine hyperbaric oxygen(HBO) in bone nonunion treatment .Methods Totally 50 standard New Zealand white rabbits were chosen ,and 48 rabbits were successfully made to models .Then ,they were divided into four groups by using the random number table ,12 in each group . The group A was in ESW combine HBO group ;The group B was in hyperbaric oxygen group ;The group C was in pure ESW group ;The group D was in control group .X‐ray inspected before treatment and after treatment in 4 、8 、12 weeks .The calcium con‐tent was checked ,the osteoblast in bone callus was observed by the optical microscope ,and the data was analyzed by statistics .Re‐sults There was a significant difference in 4 ,8 ,12 weeks between group A and group B ,C ,D in the nonunion gap(P< 0 .05) ,there was significant difference in 4 ,8 ,12 weeks between group A and group B ,C ,D in the generation bone callus(P< 0 .05) .Callus calci‐um content of group A was higher than group C ,the difference was statistical significance(P< 0 .05) ,there was significant differ‐ence in 4 ,8 weeks between group A and group C in callus osteoblast count(P < 0 .05) .Conclusion ESW combine HBO treatment for bone nonunion is better than pure ESW therapy ,simple hyperbaric therapy has no obvious help for the treatment of bone nonun‐ion ,HBO can be used as a good synergy method in the extracorporeal shock wave treatment of bone nonunion .
5.Diagnosis and Treatment of acute epidural hematoma with mixed density on CT
Xiaobin ZHOU ; Runlong LAI ; Yong LI ; Dianhui TAN ; Yu CHEN
Chinese Journal of Primary Medicine and Pharmacy 2012;(8):1145-1146
ObjectiveTo discuss the clinical characteristics and therapeutic strategy of acute epidural hematoma(EDH) with mixed density on CT.MethodsThe clinical data of 45 patients with acute EDH with mixed density on the first CT after trauma were analyzed retrospectively.Acute EDH form trauma with mixed density on CT images were compared with those which had homogenesis density on CT images at the same time.ResultsThe opportunity of increasing size of hematoma and the mortality was significantly higher in mixed density hematoma( 82.1%,16.2% )than that of homogenesis density( 17.7%,2.3% ) ( all P < 0.01 ).ConclusionEDH with mixed density was a hyperacute EDH.The operation for acute EDH from trauma with mixed density on CT image should be prompt.
6.Application of Typodont-based table clinic competition in undergraduate orthodontic educa-tion
Jianru YI ; Zhihe ZHAO ; Wenli LAI ; Wei ZHENG ; Yu LI
Chinese Journal of Medical Education Research 2013;(9):915-917
Objective To evaluate the effectiveness of Typodont-based table clinic competition (TCC) on undergraduate orthodontic education. Methods Students who have finished basic orthodon-tic courses made diagnosis,treatment strategy and performed orthodontic treatment for malocclusion cases on Typodonts. A self-design questionnaire was employed to investigate their perception to this pedagogy. Results The majority of participants(82.2%-92.9%) highly evaluated Typodont-based TCC. Conclu-sions Typodont-based TCC course is conducive to arousing students' study internets and to promoting association between theory and practice.
7.Intraarterial embolization combined with resection for the treatment of huge tumors in the buttocks
Biming LIU ; Yu ZHAO ; Hua ZHANG ; Yongqiang LI ; Lai WEI
Chinese Journal of General Surgery 2009;24(4):304-306
Objective To evaluate a combination therapy for huge tumors in the buttocks.Methods A total of 11 patients from our hospital were collected,among them 5 cases were of hemangioma,4 cases of neurofibroma,2 cases of soft tissue sarcoma.Before definite surgical resection all cases received tumor embolization with silk thread and gelatin-sponge article using Seldinger's technic.Subsequently,all patients underwent a successful tumor resection. Results Superselective embolization for all the cases'feeding arteries resulted in recession of the tumors and relatively well-demarcated margins,and all the lumps became softer.and the local pain was alleviated.Surgical resection could be radical with avoidance of fatal intraoperative hemorrhage.The 5 cases of hemangioma had a average operative bleeding of 450 ml,4 cases of neurofibroma had 420 ml,2 cases of soft tissue sarcoma had 150 ml.No patients needed intraoperative and postoperative blood transfusion.The operation time was about 2-3 hours,the normal tissues were preserved and the contour and function of the diseased limbs were very good.One case had a delayed incision healing,and the others had a healing by the first intention.There was no recurrence and other complications (like deep venous thrombosis)during a follow-up period of 4-8 months. Conclusions Surgical resection combined with interventional embolism for the treatment of huge tumors in the buttocks can reduce the risk of bleeding effectively during operation.It can improve the success rate of operation leading to satisfactory results.
8.Diagnosis and Treatment of acute subdural hematoma
Mingwen ZHANG ; Runlong LAI ; Yong LI ; Tianbo ZHANG ; Yu CHEN
Chinese Journal of Primary Medicine and Pharmacy 2011;18(2):150-152
Objective To investigate the clinical characteristics and therapeutic strategy of acute subdural hematoma. Methods A restrospective study was carried out with a total of 94 consecutive ASDH patients who were confirmed through computed tomographic scan and obtained the clinical characteristics by experienced neurosurgeons.15 cases werepure acute subdural hematoma and the other 79 cases were acute compound subdural hematoma according to CT scan. Results In accordance with the GOS,36 cases had good recovery,19 cases had moderate disability,17 cases had severe disability and 22 cases dead. Conclusion The most important treatment for pure acute subdural hematom was to diagnose the source of bleeding, and acute compound subdural hematoma had poor prognosis than pure acute subdural hematoma since the traumatic severity. Early decraniuim by large bone flap to treat acute compound subdural hematoma could improve survival rate,reduce the fatality rate and decrease postoperative complications.
9.Survey and research on peroxy acetic acid for lipid peroxidation and damage to DNA in human being.
Xiao-tao ZHOU ; Li-rui FAN ; Cui-lai JIA ; Yu-fang ZHONG ; Yu-guang CAO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2006;24(5):286-287
Adult
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Comet Assay
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DNA Damage
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drug effects
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Female
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Humans
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Lipid Peroxidation
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drug effects
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Male
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Peracetic Acid
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toxicity
10.Design and application of psychological intervention paths for ascites type of advanced schistosomiasis patients
Ruyi LAI ; Zhiwei SHAO ; Huiqiong YU ; Lile LI ; Yan MEI ; Yu HE
Chinese Journal of Schistosomiasis Control 2014;(6):662-664
Objective To explore the design and application of psychological intervention paths for ascites type of advanced schistosomiasis patients. Methods A total of 156 ascites type of advanced schistosomiasis patients were divided into an inter?vention group and a control group with 78 cases each. A psychological intervention path table was designed in accordance with the psychological characteristics and demands of the advanced schistosomiasis patients. Five steps were used to guide the nurses involved to carry out the psychological intervention. Results Before the intervention there were no statistically significant dif?ferences all P>0.05 between two groups in SAS SDS WHOQOL?BRER scores but after the intervention all the evalua?tion indexes improved in the intervention group and there were statistically significant differences between the intervention group and control group in SAS SDS WHOQOL?BRER scores all P<0.05 . Conclusion The application of psychological inter?vention paths for ascites type of advanced schistosomiasis patients can improve their negative emotions and qualities of life.