Cardiovascular Diseases ; epidemiology ; prevention & control ; China ; epidemiology ; Female ; Humans ; Hypercholesterolemia ; prevention & control ; Hypertension ; prevention & control ; Life Style ; Male ; Risk Factors

Helicobacter pylori is one of causes of gastric cancer. It can cause mucosal inflammation cytokines aggregation,gastric mucosal damage;and through a variety of ways to activate epithelial cells multiple oncogenic pathways,including phosphatidylinositol 3 kinase( PI3K)pathway,Wnt-β-catenin and epoxidized synthase-2(COX-2)-prostaglandin E2 antibody(PGE2)pathway,so as to change the gastric stem cell micro-environment and disrupt the gastric stem cell differentiation and proliferation,making the normal gastric stem cells evolved into cancer stem cells.

Low intensity millimeter(6mm,50GHz,100mW) wave was used to irradiate to 15 blood samples. The radiation time respectively were 15min、30min and 60min.Series rheological and biophysical parameters about the erythrocyte were systemically tested. There included viscosity of blood 、deformability and congregating ability of erythrocyte、hemolysical fragility 、anion transport in erythrocyte membranes and configuration of erythrocyte etc. From the point of biophysics, the biological effects of low intensity MMW to cells were investigated.

Objective To investigate the therapeutic effect of inhaled budesonide suspension combined with psychological intervention on children with asthma. Methods 64 children with asthma were enrolled in our hospital from October 2015 to December 2016. They were divided into experimental group and control group, 32 cases in each group. The control group was treated with inhaled budesonide suspension.The experimental group was treated with inhalation with budesonide suspension combined with psychological intervention, the treatment efficiency and symptom improvement were compared and analyzed in the two groups. Results The effective rate of the experimental group was 96.87%, which was higher than that of the control group 84.37%, the difference was statistically significant (P<0.05). The symptoms of cough, wheezing, wheezing and dyspnea in the experimental group was obviously better than that in the control group, the difference was statistically significant (P<0.05). Conclusion The effect of inhalation with budesonide suspension combined with psychological intervention in the treatment of children with asthmais pbvious.It can effectively improve the clinical symptoms, and promote recovery of children.

Objective To investigate the status of the anxiety and depression in the patients with paralysis after spinal cord injury, and the measures to cope with it. Methods Sixty cases of patients with paralysis after spinal cord injury were evaluated with Self-Rating Anxiety Scale (SAS) and SelfRating Depression Scale (SDS), the results were compared with those of the domestic norm of healthy individuals. Results The scores of patients with paralysis after spinal cord injury were higher than that of domestic norm of healthy individuals. 54 cases had anxious symptom (90.00%), and 37 had depression.The causes led to anxiety and depression mainly came from the suffering of the disease, the influence of the work as well as the study and the cost of the treatment. Conclusions The patients with paralysis after spinal cord injury had mental problems, they need to be interfered with by healthy education and mental nursing in order to promote rehabilitation.

Objective:To investigate characteristics of masticatory movement path in young adults with AngleⅡ1 malocclusion.Meth-ods:1 5 youths with normal occlusion(group Ⅰ)and 1 5 with AngleⅡ1 malocclusion(group Ⅱ)were included.Mandibular movement paths of the incisal point of the incisor during unilateral-sided gum-chewing were recorded by the BioEGN mandibular kinesiography an-alyzer.Both maximal distances and directions (FH-opening/closing angles)in sagittal plane were analyzed.The statistic analyses were performed with SPSS 1 3.0 software.Results:Lateral distances of left masticatory movement path in Group I and Group II were (8.24 ±1 .48)mm and (6.58 ±2.49)mm,those of right(8.05 ±1 .05)mm and (6.42 ±2.47)mm,respectively(P <0.05).The aver-age of FH-opening/closing angle of masticatory movement path in Group I was higher than that in Group II at each level(P <0.05)ex-cept 0.5 mm point in the left masticatory movement path.Conclusion:Maximal lateral distance and FH-opening/closing angle of mas-ticatory path in young adults with AngleⅡ1 malocclusion are less than those with normal occlusion.

Objective To investigate the correlations of the levels of serum total cholesterol (TC),high density lipoprotein(HDL),and low density lipoprotein (LDL) with tumor node metastasis (TNM) staging and Lauren's classification in gastric cancer.Methods The blood lipid levels of 157 cases of gastric cancers,80 cases of benign gastric diseases,and 80 cases of normal subjects were detected by the Hitachi 7170A automatic biochemical instrument,and these values were statistically compared with SPSS 19.0.Results The contents of serum TC,HDL,and LDL in the group of gastric cancers were lower than those in the groups of normal subjects and benign gastric diseases (P ＜ 0.05).The contents of serum HDL levels were decreased with the increase of the TNM stage in patients with gastric cancer,and were all lower than the benign gastric diseases and the health control group (P ＜ 0.05).No statistically significant correlation was found in the levels of serum TC,HDL,and LDL in Lauren's histological types of gastric cancers (P ＜0.05).Conclusions Abnormal lipid metabolism had already appeared in gastric cancer,and the decreased serum HDL levels was correlated with TNM stage of gastric cancer.Detection of the changes of lipid levels in patients might be beneficial to the screening and prognosis of gastric cancer.

Purpose: To investigate a clinical treatment for allergic asthma. Method: Acupoint application was used, and its effect was compared with that of Western medicine to evaluate the results. Results and Conclusion: It was found that the long-tern effect of acupoint application was significantly better than that of aminophylline; acupoint application had obviously different effects on different types of asthma based on TCM differentiation of syndromes; its short-term effect was not significantly related to the course and condition of the disease. It is indicated that acupoint application is an effective, convenient and safe treatment with little side effect for asthma.

OBJECTIVE:To evaluate the antibiotic activity of Moxifloxacin (MFX) combined with Cefoperazone/Sulbactam (CPZ/SBT) against clinical common resistant bacteria for clinical reference of rational use of antibacterials.METHODS: The MIC of two antibiotics used alone or in combination on staphylococcus aureus,Klebsiella pneumoniae,Pseudomonas aeruginosas(50 strains,respectively)and Escherichia coli,enterobacter cloacae(20 strains,respectively)were detected respectively by Vitek-32 Model (Full Automated bacterium Detection Device) and the fractional inhibitory concentration(FIC) index was calculated. RESULTS: The combination of two antibiotics significantly reduced MIC on 190 common resistant pathogenic strains and enhanced antibiotic action. Their antibacterial action in vitro was characterized by synergism and additive action. CONCLUSION: The study can present reference for hospital treatment of infection induced by common drug-resistant bacteria.

Objective To investigate the effect of acupuncture at the primary points of the three yin meridians of the foot on blood pressure in an animal model of high/low blood pressure and explore the specific effect of the meridian points-the primary points of the three yin meridians of the foot.Methods The study included the parts of hypertension and hypotenstion. Both parts were allocated to the primary points of the three yin meridians of the foot, non-acupoint, model and blank groups, six rats each. Except the model and blank groups, all the groups were given acupuncture treatment for seven consecutive days. Blood pressure was measured after the completion of treatment. Five consecutive measurements were made in each rat. Mean values of blood pressure were taken.Results For the part of hypertension, blood pressure at each time point was higher in the acupuncture groups than in the blank control group and lower than in the model group, and there were statistically significant differences (P<0.05), indicating that acupuncture at the primary points of the three yin meridians of the foot has a hypotensive effect. The hypotensive effects of Taichong and Taixi were better than those of Taibai and the non-acupoint (P<0.05). The hypotensive effects of Taichong and Taixi were equal (P>0.05). The hypotensive effect of Taibai was equal to that of the non-acupoint (P>0.05). For the part of hypotension, blood pressure at each time point was lower in the acupuncture groups than in the blank control group and higher than in the model group, and there were statistically significant differences (P<0.05), indicating that acupuncture at the primary points of the three yin meridians of the foot has a pressor effect. The pressor effect was worse in the the non-acupoint group than in the primary points of the three yin meridians of the foot group (P<0.05). The pressor effects of Taibai and Taixi were equal but worse than that of Taichong (P<0.05).Conclusions Acupuncture at the primary points of the three yin meridians of the foot has a specific bidirectional regulating effect on blood pressure. Of them, point Taichong produces a best bidirectional regulating effect on blood pressure.