PURPOSE: The study has been done to evaluate the significance of APR test predictive of neonatal infection. METHODS: A study was made on 76 cases of clinically infeected neonates who had been admitted at the NICU of Chungnam National Unoversity Hospital during the period from January, 1996 to July, 1996 in order to know the significance of APR test predictive of neonatal infection. RESULTS: 1)The APR test Of Control group (20 cases) shows negative results on 19 cases (95%) and positive result on 1 case (5%). 2) The APR test of Patient group (76 cases) shows negative results on 17 cases (22.3%) and positive results on 49 cases (77.7%). Of cases with positive result, one points were on 23 cases (30.5%), two points were 25 cases (32.8%), three points were on 11 cases (14.4%) and More than one point were of 59 cases. The sensitivity of APR test, WBC count and CRP is 77.7%, 35% and 62.496, respectivitly. As above result, APR test has a high sensitivity. 3) APR positive values are not significantly different between those of premature and fullterm patients. 4) APR values are more significant than WBC count or CRP value to predict the neonatal infection. 5) The APR test is rnore useful for prognostic correlation than other index. CONCLUSION: APR test is very sensitive and significantly useful predictive of neonatal infection.
Chungcheongnam-do ; Fever ; Humans ; Infant, Newborn

There is no definite histological criteria which can predict the biologic behavior of meningiomas, although resectability is the most important factor in terms of recurrence. For grading meningiomas, various factors have been studied, such as hypercellularity, nuclear pleomorphism, small cells with high N/C ratio, prominent nucleoli (PN), frequent mitosis, loss of architecture, focal necrosis (FN). We investigated 116 meningiomas to evaluate the correlation between the factors and the proliferative activity using AgNORs and MIB-1 labelling index (LI). They were divided into 3 groups: Group A includes meningiomas with none of the factors; group B with one of the factors; group C with two or more factors. MIB-1 LI was correlated with each factor, but AgNORs was not. There was a statistical difference among group A (<1.28%), B (2.7%) and C (5.1%) (p<0.05) using MIB-1 LI. FN was the most frequently associated with other factors, and it had the highest MIB-1 LI (6.31%). MIB-1 LI of group B was 5.1 2.3%. In group B, the most frequent combination was FN and PN, and it showed the highest MIB-1 LI (5.74%). This study indicates that FN and PN are important for diagnosis of atypical meningioma, and MIB-1 LI appears to be a useful method for estimating the proliferative activity of meningiomas, and 5% or more of MIB-1 LI could help in making a diagnosis of atypical meningioma.
Diagnosis ; Meningioma* ; Mitosis ; Necrosis ; Recurrence

Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from a preexisting benign epidermoid cyst. We report a rare case of primary intracranial squamous cell carcinoma in the brain stem with a cerebellopontine angle (CPA) epidermoid cyst. A 72-year-old female suffered from progressive left hemiparesis, difficulty in swallowing, and right hemifacial numbness. Diffusion-weighted magnetic resonance imaging revealed a high signal intensity (SI) lesion in the CPA region and an intra-axially ring-enhanced cystic mass in the right brain stem with low SI. Whole-body positron emission tomography showed no evidence of metastatic disease. The histological findings revealed a typical epidermoid cyst in the CPA region and a squamous cell carcinoma in the brain stem. We speculate that the squamous cell carcinoma may have been developed due to a chronic inflammatory response by the adjacent epidermoid cyst. The patient underwent a surgical resection and radiotherapy. After 12 months, she had no evidence of recurrence.
Aged ; Brain ; Brain Stem ; Carcinoma, Squamous Cell ; Cerebellopontine Angle ; Deglutition ; Epidermal Cyst ; Female ; Humans ; Hypesthesia ; Magnetic Resonance Imaging ; Paresis ; Positron-Emission Tomography ; Recurrence

PURPOSE: This study was conducted to investigate the relations among gratitude, depression, and psychological well-being among clinical nurses. METHODS: The participants were 411 clinical nurses, working in U city. Data were collected during the four months, April to June, 2012. Data were analyzed using descriptive analysis, t-test, ANOVA, Pearson correlation coefficients and multiple regression with the SPSS/WIN 20.0 program. RESULTS: The mean scores for gratitude and psychological well-being were above average. The mean score for depression presented a probable depression level. Psychological well-being in clinical nurses was significantly correlated with gratitude (r=.55, p<.001) and depression (r=-.62, p<.001). The significant predictors of psychological well-being for clinical nurses were depression (beta=-.47, p<.001) and gratitude (beta=.34, p<.001), which explained 48.0% of the variance in psychological well-being. CONCLUSION: The results indicate that it is necessary to develop depression reduction and gratitude enhancement programs to improve the psychological well-being of clinical nurses.
Depression*

PURPOSE: The purpose of this study was to identify levels of cognitive distortion, depression, and gambling severity and to identify the influences of cognitive distortion and depression on gambling severity in Koreans with a gambling disorder. METHODS: The participants in this study were 150 Koreans with a gambling disorder. Data were collected using self-report structured questionnaires which included individual characteristics, the Gambling Related Cognitions Scale, the Center for the Epidemiologic Studies Depression, and the Problem Gambling Severity Index. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficients, and multiple regression. RESULTS: Gambling severity had a significant correlation with gambling related cognitions scale-perceived inability to stop gambling (r=.29, p<.001) and depression (r=.34, p<.001). Among predictors, depression (β=.24, p=.035) and type of housing tenure (β=.26, p=.022) had statistically significant influence on gambling severity. The explanatory power of this regression model was 17.0% (F=3.72, p=.003). CONCLUSION: The findings from this study indicate that interventions to decrease depression are essential to decrease the gambling severity of Koreans with gambling disorder.
Cognition ; Depression* ; Epidemiologic Studies ; Gambling* ; Housing

BACKGROUND: We observed fentanyl known as centrally-acting antitussive agents provoke a cough response in some patients at induction of anesthesia. This may be of clinical importance. METHOD: 121 patients (ASA class I) were assigned randomly to 4 groups. Each group was given different doses of fentanyll Group 1 (n=30); 0.5ug/kg, Group 2 (n=30); 1ug/kg, Group 3 (n=33); 2ug/kg, Group 4 (n=28); 4 g/kgl, within 1 second through a peripheral venous cannula before induction of anesthesia. All patients were observed carefully in order to detect a cough response and any side effects. RESULT: The incidences of FCR (Fentanyl Cough Response) were 0% in Group 1, 10.0% in Group 2, 30.3% in Group 3, and 39.3% in Group 4. The ED50 of FCR was 4.25ug/kg. The mean onset-time from the end of fentanyl administration to the beginning of coughing was 12.5 seconds. FCR was decreased with aging, but not affected by weight, height, or smoking. Other serious side effects were not accompanied. CONCLUSION: Fentanyl can evoke the pulmonary chemoreflex dose-dependently and the ED50 was 4.25 g/kg.
Aging ; Anesthesia ; Antitussive Agents ; Catheters* ; Cough* ; Fentanyl* ; Humans ; Incidence ; Reflex* ; Smoke ; Smoking

No abstract available.
Alleles* ; Base Sequence* ; Clone Cells* ; Cloning, Organism* ; HLA-DR Antigens

PURPOSE: This study was conducted to investigate the factors that affect subjective well-being in nursing students. METHODS: A total of 236 nursing students participated in the study. Data was collected from November through December 2013 using a self-reporting questionnaire that surveyed the level of gratitude, interpersonal relationship ability, subjective happiness, and life satisfaction. Data was analyzed by descriptive analysis, t-test, ANOVA, Pearson correlation coefficients and multiple regression with the SPSS/WIN 18.0 program. RESULTS: Subjective happiness positively correlated with gratitude (r=.41, p<.001) and interpersonal relationship ability (r=.55, p<.001). Life satisfaction positively correlated with gratitude (r=.53, p<.001) and interpersonal relationship ability (r=.37, p<.001). Significant predictors of subjective happiness included gratitude (beta=.38, p<.001), interpersonal relationship ability (beta=.28, p<.001) and major satisfaction (beta=.17, p=.002). The regression model explained 39.3% of subjective happiness. Significant predictors of life satisfaction included gratitude (beta=.42, p<.001), academic achievement (beta=.15, p=.006), interpersonal relationship ability (beta=.16, p=.008) and major satisfaction (beta=.12, p=.035). The regression model explained 35.3% of life satisfaction. CONCLUSION: To improve subjective well-being among nursing students, nurse educators should develop educational intervention programs to promote gratitude and interpersonal relationships.
Happiness ; Humans ; Interpersonal Relations ; Surveys and Questionnaires ; Students, Nursing*

The mixed gangliocytoma-pituitary adenoma is a very rare intracranial neoplasm, and it is frequently associated with endocrine symptoms; acromegaly, Cushing's disease, galactorrhea and amenorrhea. Morphologically it shows a mixture of gangliocytoma and pituitary adenoma in various proportions. In the area of gangliocytoma, there is no neoplastic glial component. The portion of pituitary adenoma consists mainly of chromophobe cells. There are three hypotheses in its histogenesis. We report a case of a 41 year-old lady presented with acromegaly and amenorrhea existing for 3 years. On magnetic resonance image, there is a dumbell-shaped mass in the sellar region. Histologically it showed typical features of mixed gangliocytoma-pituitary adenoma. This case is presented in the view of its rarity and interesting possible histogeneses.
Acromegaly ; Adenoma* ; Adult ; Amenorrhea ; Brain ; Brain Neoplasms ; Female ; Galactorrhea ; Ganglioneuroma ; Humans ; Pituitary Neoplasms ; Pregnancy

No abstract available.
Animals ; Clone Cells* ; Cloning, Organism* ; DNA, Complementary* ; Leptin* ; Rats* ; Receptors, Leptin*