The author got an opportunity to know about the Thai traditional medicine, especially its application and efficacy in treatment of Bi syndrome via the communication with Thai healers in the duration of teaching and working in Chandrakasem Rajabhat University due to an invitation.This paper will simply discuss the similarities and differences between the treatments with traditional Thai medicine and traditional Chinese medicine for Bi syndrome in terms of their theory systems, the understanding of Bi syndrome, as well as the characteristics of therapies.And I hope this paper will provide certain help in the academic exchanges between these two traditional medicines.

MicroRNA (miRNA),an abundant class of small non-coding RNA,are abundant in the central nervous system where they play important roles in the neuronal development and plasticity.Moreover,the relationship between miRNA dysfunction and neurological diseases become more and more apparent.Recent studies show that the misregulated expression of miRNA out of control is closely related to the development of glioma.In this review we discussed the progress on the study of miRNA in Glioma.

The management of hospital office is one of the important part of hospital management .The paper briefly introduces the functions and features of hospital office , analyzes the present situation and existing problems . By applying PDCA Circulation Method , we can improve and optimize the hospital office and constantly enhance the management level of hospital office .

Multiple myeloma (MM) is a hematologic malignancy of differentiated plasma cells that accumulate in the bone marrow,where a complex microenvironment made by different cell types supports proliferation,survival,and drug resistance of tumor cells.MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at post-transcriptional level.Emerging evidence indicates that miRNAs are aberrantly expressed or functionally deregulated in MM cells as the result of multiple genetic or epigenetic mechanisms and that also the tumor microenvironment regulates MM cell functions by miRNAs.Consistently,modulation of miRNA levels in MM cells has been demonstrated to impair their functional interaction with the bone marrow microenvironment and to produce significant antitumor activity to overcome the protective bone marrowmilieu.This review will describe the most recent findings on miRNA function in the context of MM bone marrow microenvironment,focusing on the therapeutic potential of miRNA-based approaches.

Objective To explore the relationship between Monoamine oxidase A (MAOA) receptor gene,catechol-O-methyltransferase (COMT) receptor gene,dopamine D3 receptor(DRD3) gene and 5-HT2C receptor gene(5-HT2c) of Han population in northern China and obsessive compulsive disorder.Methods Polymerase chain reaction amplification determination of MAOA-T1460C,COMT-Val158Met,DRD3-Ser9Gly,5-HT2c-C ys23Ser four loci receptor gene polymorphism in 164 patients with OCD patients including 103 core pedigrees of fragment length polymorphism,and association and linkage disequilibrium (TDT)analysis.Results There was no significant difference of MAOA-T1460C,COMT-Val158Met,DRD3-Ser9Gly,5-HT2c-Cys23Ser four receptor gene in the patient group and the control group of genotype and allele distribution difference(P＞0.05),four receptor gene loci were in accordance with the balance of the H-W,the MAOA-T1460C receptor gene in female patients group and control group,the early group and control group,which has forced thinking and difference of compulsive behavior group and the control group,only the obsessional group and the control group of genotype and allele distribution was statistically significant(P＜0.05),and the family group between chain(P=0.0001) ;5-HT2c-Cys23Ser receptor gene in the case group and the control group,male both forced thinking and compulsive behavior group and control group differences in genotype and allele distribution was statistically significant (P＜ 0.05),and between family groups exist chain (P=0.0389) ; COMT-Val158Met receptor gene in the control experiments were no significant difference(P＞0.05),and with the house group does not exist between the chain (P=0.0622) ;DRD3-Ser9Gly receptor gene in the control experiments were no significant difference(P＞0.05),and with the family groups there is no chain(P=0.1101).Conclusion MAOA-T1460C receptor gene polymorphism and 5-HT2c-Cys23Ser receptor gene polymorphisms may be the susceptible gene of obsessive compulsive disorder.

Objective To review the examination techniques and the current research progress of the magnetic resonance diffusion weighted-imaging (DWI) used in liver. Methods The recent and relevant literatures about the principles and the current study situation of liver DWI were scrutinized and analyzed retrospectively. In addition, the existing problems of liver DWI were discussed. Results DWI could demonstrate the normal and abnormal structure and function through measuring the diffusion motions of water molecule in the liver. With the improving technology and better understanding of diffusion dynamics, DWI has been used for the diagnosis and differential diagnosis for hepatic diseases. Conclusion DWI as a non-invasive examine method, may provide valuable functional information for clinical diagnosis and treatment.

Objective To investigate the pressing time and puncture site bleeding after extubation of superficial venous catheter in elderly patients.Methods Four hundred elderly inpatients were selected from respiratory department during June 2015 and December 2015 and were divided into two groups:200 patients as experimental group with pressing time of 5-6 minutes and 200 patients as control group with pressing time of 3-4 minutes.The same group of nurses pressed the puncture site after extubation and changes on skin and vessels were observed,which was to find out the optimal pressing time after extubation of superficial venous catheter in elderly patients.Results The presence of bleeding,bruising,success rate of the second puncture,swelling,pain and degree of comfort were compared between two groups and significant differences were found (P＜0.05).Conclusion Compared with those in control group,less bleeding,bruising,swelling,and pain,higher success rate of the second puncture and lower degree of comfort were found in experimental group.

Objective To observe the mini -invasive treatment for patients with medium volume of hyper-tensive criatocapsular hemorrhage.Methods 59 patients with medium volume of hypertensive criatocapsular hemor-rhage(20 -30mL)were selected and randomly divided into mini -invsasive surgery group and conservative treatment group.Two groups were compared the average length of stay,hospital costs and clinical effect.Results The avergae hospital stay (14 ±3.26)days and avergae cost (1.1 ±0.33)ten thousand yuan of the mini -invsasive surgery group was lower than those of the conservative treatment group (25 ±6.58)days and (1.8 ±0.56)ten thousand yuan],the differences were statistically significant (t =7.999,5.768,all P <0.01).After 3 months follow -up,the recovery of self -care ability after operation estimated by ADL scores in the mini -invsasive surgery group was significantly better than that in the conservative treatment group(12 /31 vs.25 /28,χ2 =16.093,P <0.01).Conclusion For patients with medium volume of hypertensive criatocapsular hemorrhage(20 -30mL),minimally invasive surgery can shorten hospital stay,reduce the financial burden of patients,and improve the prognosis significantly.

Objective: The relationship between intracranial pressure (ICP) and visual evoked potential (VEP) or brainstem auditory evoked potential(BAEP)was investigated. Method:An acute intracranial hypertension animal model was established in ten anesthetized rabbits. The changes of VEP and BAEP were observed by an AXON Systems Sentinel-4 Neurologid monitor at different levels of ICP,which were monitored with a fiberoptic transducer being inserted into the epidural space through a burrhole. Result:Both latencies of waves P_1 and N_2 of VEP was positively correlated with the ICP(r=0.62,r=0.60,P

The initial definition of stress and its development were briefly retrospected with elucidating the significance of stress in life sciences study. Stress is involved in a variety of physiological and pathophysiological processes. Description of the advances focusing on the relationships between stress and several body systems including nervous system, immune system and cardiovascular system etc. and on the stress molecules and signal transduction was carried out. The ultimate aim of the review is to emphasize the importance and the distinct position of stress during the development of modern bio-medicine, and to further attract more attention to the research field of stress from more scientists.