This paper introduces a statistics method for the segmentation evaluation for the head MRI. A new evaluation scheme proposed, the evaluation result is analyzed objectively by the statistic method. Genetic neural network algorithm proves with a stronger antinoise ability than other ones. The statistic method is helpful for evaluating the segmentation objectively.

Child ; Humans ; Male ; Thyroiditis, Suppurative ; pathology

Acupoint,as the special body surface part where the qi of zang-fu and meridians infuses, arouses the effect of acupuncture and moxibustion. Through the exploration for the origin and the evolution of acupoint, and the integration of the related data about acupuncture-moxibustion theory and modern research, it is believed that acupoint is not fixed and it may be in a state of dynamic change. Also, it is bound up with body function. Acupoint is relatively static and the location is immobile while the body is in normal physiological status. When the body is under pathological condition,however, it is activated and the position is correspondingly changed.
Acupuncture Points ; Acupuncture Therapy ; Humans ; Meridians

Inflammation plays a pivotal role in atherogenesis. In addition to being a potent predictive and prognostic marker for major cardiovascular events, recent evidence indicates that C-reactive protein (CRP) might directly promote atherogenesis by exerting direct effects on vascular cells. Thus, CRP will become important novel pharmaceutical targets for the treatment of atherosclerosis. This review presents an overview of the current knowledge about the pathological role of CRP in atherosclerosis initiation and progression.

Objective To explore the glucose and liplid metabolism changes of pregnant rats and the birth weight of their offsprings due to pregnancy malnutrition,including overnutrition and undernutrition.Methods Thirty pregnant Wistar rats were randomly divided into three groups on the day of conception,the high-fat-diet group,normal control group and 50％ food-restricted diet group.Increase of body weight and serum level of triglycerides,high-density lipoprotein,low-density lipoprotein,oral glucose tolerance test (OGTT) and insulin release test(IRT) levels during pregnancy were measured.The birth weight of offsprings was recorded within 12 h after birth.One-way ANOVA,LSD or Dunnett T3,and Chi-square test were applied for statistical analysis.Results The body weight at late pregnancy and the level of triglycerides and low-density lipoprotein were significantly increased in the high-fat-diet rats compared to normal control ones [(1.68±0.13) mmol/L vs (0.78±0.08) mmol/L,(0.57±0.04) mmol/L vs (0.35±0.07) mmol/L; both P＜0.01].While the level of high-density lipoprotein of high-fat-diet rats was lower than that of the normal control rats [(0.56±0.06) mmol/L vs (1.09±0.08) mmol/L,P＜0.05].The level of triglycerides,low density lipoprotein and high density lipoprotein in 50％ food restricted group [(0.47±0.06) mmol/L,(0.21±0.06) mmol/L and (0.42±0.05) mmol/L] were lower than the control group (all P＜0.05).Impaired glucose tolerance,abnormal OGTT and IRT results were found in both high-fat-diet and 50％ foodrestricted diet rats.The fasting plasma glucose level in high-fat-diet group was significantly increased in late pregnancy compared to the control [(6.63±0.53) mmol/L vs (4.90±0.26) mmol/L,P＜0.05],while there was no significant difference between rats in 50％ food-restricted diet [(4.18±0.26) mmol/L]and control group (P＞0.05).There was no statistical difference in fasting serum insulin level among the three groups.The average birth weight was significantly increased in high-fat-diet rats than in the control group [(6.14±0.31) g vs (5.73±0.26) g,P＜0.05],and the incidence of macrosomic newborn rats in the high-fat-diet group was also higher than that of the control group [19.2 ％ (19/99)vs 7.84％(8/102),P＜0.05].The birth weight of offspring in 50％ food-restricted diet group was decreased with their average birth weight of (4.54±0.23) g,which was lower than that of the control group (P＜0.05).The incidence of macrosomic [13.40％ (11/76)] and low birth weight newborn rats [15.90％ (13/76) vs 3.92％(4/102)] in food-restricted diet group were both higher than in the control group (P＜0.05); and smaller number of offsprings was obtained than the control group (76 vs 102,P＜0.05),the number of offsprings in high-fat-diet group was 99,which was less than the control group without statistical difference (P＞0.05).Conclusions Pregnancy malnutrition,including overnutrition and undernutrition,may affect the lipid metabolism and glucose tolerance of pregnant rats,leading to insulin resistance,and may also contribute to the abnormal birth weight of the offspring,including macrosomia and low birth weight.

BACKGROUND:Silver ion dressing can reduce tissue necrosis, accelerate the epithelial formation, relieve the patient’s pain during the treatment, and strengthen various growth factors for wound repair, which is based on the theory of wet healing theory. It has obvious advantages for chronic wound healing, such as anti-infection and promoting wound granulation and epithelial hyperplasia.
OBJECTIVE:To observe the efficacy of silver ion dressing used in healing of chronic wound.
METHODS:A total of 40 patients who had chronic wounds were selected from Tangshan Branch Hospital of Nanjing General Hospital of Nanjing Military Command. Al cases were divided into two groups. The treatment group was treated with silver ion dressing, and the control group was treated with routine dressing. Secretions extracted from wound were used for bacterial culture prior to and 7, 14, and 21 days after treatment. Healing condition and velocity were observed and wound pain was assessed using visual analog scale.
RESULTS AND CONCLUSION: The detection rate of wound bacteria in the treatment group was significantly lower than that of the control group (P<0.05). And the time of healing was shorter in the treatment group than the control group (P<0.05). Wound pain during dressing change was relieved (P<0.05). Medical costs showed no difference between the two groups (P>0.05). No adverse reaction occurred in the two groups. These findings indicate that silver ion dressing used in chronic wound healing can prevent infection and promote wound granulation or epithelial hyperplasia. It can effectively promote wound healing and has no bad reaction.

The angiotensin converting enzyme (ACE) gene is one of the main candidate genes of the genetic predisposition study of stroke,however,the correlation between the ACE gene polymorphism and stroke remains controversial.This article reviews the advances in research on the correlation between the ACE gene polymorphism and stroke in recent years.

Objective To explore the relationship between retinal vascular occlusion and carotid artery atherosclerotic (CAA) plaque by color Doppler ultrasonography.Methods Carotid artery color Doppler ultrasonography was performed in 65 patients with retinal vascular occlusion (case group) and 50normal controls (control group).To acknowledge the role of the CAA plaque in the ocurrence of retinal vascular occlusion by the detection rate of CAA plaque and stenosis degree of carotid arteries.Results The detection rate of CAA plaque was 64.62％(42/65) in case group,which was higher than that in control group [22.00％(11/50)],and there was significant difference (P＜0.05).Mild stenosis had 34 cases,moderate stenosis had 6 cases,severe stenosis had 2 cases in case group,and 8,3,0 case respectively in control group.There was significant difference in stenosis degree of carotid arteries between two groups (P ＜ 0.05).Conclusions CAA plaque is closely related to the ocurrence of retinal vascular occlusion.Color Doppler ultrasonography is the simplest and most effective method to monitor CAA plaque which has clinical significance in prevention and treatment of retinal vascular occlusion.

To raise the quality of pathology teaching and students' abilities of possessing knowl-edge,we reformed the teaching method. Applying information feedback between teachers and students in pathological teaching can effectively solve students' confusion and improve teacher's teaching quality. Stu-dents' interests and initiative in pathology learning were aroused and teachers' responsibilities were pro-moted by teaching reform,thus having satisfactory results were obtained.

ObjectiveTo analyze the clinical characteristics,effects of adjuvant therapy and influential factors of gastrointestinal stromal tumors (GIST).MethodsA retrospective and multiple factor Cox model analysis on 216 cases of primary GIST diagnosed by surgery and pathology was conducted.Results The total survival rates of patients at one to five years were 94.4 ％ (204/216),90.2 ％ (129/143),88.3 ％(68/77),87.5 ％ (35/40) and 85.0 ％ (17/20),respectively.The statistically significant prognostic factors for survival rates of patients with GIST included age,location of tumor,local or total tumor resection,rupture of tumor,adjuvant treatment,recurrence,mitotic rate,and tumor size (P ＜ 0.05).Due to those influence factors,the greater of the values,the higher of the risk of death.Among those factors,whether having grass total resection played a decisive role in the prognosis of patients with GIST.Other factors,such as sex,CD117,biopsies,endoscopic mucosal erosion,and operation cutting margin had no significant relevance with the survival rate of patients (P ＞0.05).Postoperative adjuvant therapy could significantly improve the survival rate of patients with GIST,especially for patients with high risk.ConclusionSurgical treatment should be given priority to treatment of GIST,and the choice of the surgery strategies depends mainly on the location and size of tumors.The complete resection or extensive resection could improve survival rates.Age,location,total tumor resection,rupture of tumor,adjuvant treatment,recurrence,mitotic rate,and tumor size are important factors affecting prognosis and survival rate of patients with GIST,which could guide standardized clinical treatment.