To evaluate the forensic determination of post cerebral traumatic epilepsy. Methods In 21 patients, traumatic history and previous history were analysied combined with the demonstrations of electroencephalogram(EEG), X-ray, CT and MRI. Results Post-traumatic epilepsy,manily in late stage, usually occurred following serious cerebral trauma. The type of traumatic epilepsy was determined by the traumatic location and extent. Abnormal epileptic wave in scalp EEG and 24h dynamic EEG and medical image examinations were helpful for qualitative analysis. Conclusion The forensic determination of post traumatic epilepsy must be on the basis of traumatic and previous history combined with EEG, CT and MRI analysis.

The serous anti-corneum antibodies(ACAs)of 50 psoriatic patients and 32 normal con- trols were measured by Biotin Avidim Enzyme Linked Immunosorbent Assay (BA-ELISA).The results showed that ACAs of patients were significantly lower than that of the controls(P

Objective To select health individual and test serum total bilirubin and direct bilimbin in order to provide a reference range for the establishment of appropriate reference interval in this region.Methods From October to December in 2009,314 of physical examination population of Beijing Hospital were selected by questionnaire and laboratory test excluding liver and gallbladder diseases or metabolic diseases.Roche and Prodia reagents were used to test TBIL and DBIL,respectively.Reference interval was calculated by sex group and compared with the existing reference interval.Results The level of TBIL had a significant difference between different genders(P ＜ 0.01).The level of TBIL had a significant difference between two kinds of reagents(P ＜ 0.01).Using Roche reagent,the reference interval of TBIL was 7.1 ～ 27.2 μmol/L for man,and 4.8 ～ 20.9 μmol/L for woman,and the reference interval of DBIL was 1.4 ～6.8 μmol/L for man,and 0.9 ～5.7 μmol/L for woman.Using Prodia reagent,the reference interval of TBIL was 9.5 ～ 35.7 μmol/L for man,and 6.8 ～ 28.9 μmol/L for woman,and the reference interval of DBIL was 1.3 ～ 7.0 μmol/L for man,and 1.0 ～ 6.6 μmol/L for woman.Conclusions The level of TBIL and DBIL in physical examination population was higher than the existing reference interval.It is necessary to modify the existing reference interval and establish reasonable reference interval for different regions and gender,respectively.

Objective: To investigate the clinical effect of mind-regulating acupuncture therapy on peripheral facial paralysis. Methods: Two hundred subjects were divided into observation group (treated by mind-regulating acupuncture therapy) and control group (treated by points of Yang-ming meridians) with one hundred in each group. The points of Yang-ming meridians were mainly selected for control group, observation group were treated by points with the function of regulating mind besides the points of control group, for two courses with 10 treatments in course. Results: The cure rate was 65.0% and total effective rate was 99.0% in observation group, while in control group, the cure rate was 55.0% and total effective rate was 91.0%, the curative effect in observation group was prior to control group (P＜0.05). Conclusion:The therapy of mind-regulating acupuncture gives a quicker response, a shorter course of treatment and a higher cure rate.

Laser photocoagulation,intravitreal injection of antibody against vascular endothelial growth factor (VEGF) or corticosteroids and pars plana vitrectomy are current popular therapeutic approaches for diabetic retinopathy (DR).However,some DR patients still progress to irreversible blindness even after the above treatments which do not aim at the pathological mechanisms and influence factors for DR.Thus,with the further elucidation on the molecular pathological mechanisms and overall understanding of the factors affecting DR development,more and more potential therapeutic interventions such as neuron protection,vascular reconstruction and protection,gene therapy,non-VEGF dependent antineovascularization agents have been explored.Individual precise therapy based on the potential therapeutic targets would provide the promising future for DR patients.

Objective To find out the clinical characteristics related to neonate food allergy.Methods Ten subjects were diagnosed as neonate food allergy at the Third Hospital of Peking University from January 201 3 to January 201 5.The following clinical data:the gestational age,genter,age of onset,feeding,clinical manifestations,white blood cell count,eosinophilic granulocyte count,C -reactive protein(CRP),routine stool test and occult blood test,blood spe-cific IgE of cow′s milk and clinical outcomes were investigated.Results There were 4 term infants,and 6 preterm in-fants,including 2 very -preterm subjects.The gender ratio between male and female cases was 73.The age of onset from 1 day after birth to 43 days after birth,clinical investigation of neonate food allergy in 1 0 cases,and the average time was 20.3 d,the median age was 1 8.5 d,and the SD was 1 3.38 d.Their rectified gestational ages were from 30 to 37 weeks in 6 cases at onset.Four infants received breast feeding,3 infants received formula milk feeding,and the other 3 infants received mixed feeding.At onset,the symptoms were almost involved in the digestive system.The white blood cell counts of lab test were almost normal in 1 0 subjects.And eosinophilic granulocytes were elevated in 8 subjects.CRP elevated in 1 case,and those of the other 9 subjects were normal.The cow′s milk specific IgE antibody was elevated in 1 subject,and that of the other 9 subjects was normal.Two subjects were performed opened food challenge test and the finding were positive.Conclusions Both the term infants and the preterm infants can have food allergy,but the age of onset ranged widely.Breast feeding infants can also be attacked.The symptoms of the digestive tract were the main clinical manifestations of such neonates.The open -food challenge test is beneficial to diagnose but difficult to practice in the neonates.Dietetic treatment is the only method can therapy the disease.And mostly the clinical outcomes are desirable.

OBJECTIVE:To discuss the way,approach and the effects of continuing education of pharmacists in hospital.METHODS:Multimedia and lectures were adopted as the mode of teaching medical courses and exam system was established as well.RESULTS:Continuing education made up for pharmacists'lack of medical knowledge to some degree,which laid a specialty foundation for pharmacists in the clinical service.CONCLUSIONS:The mode of launching continuing medical education for pharmacists is practicable,which can make up for the current lack of clinical pharmacy graduates from medicine academy.

Objective To determine the effect of prone position (PP) ventilation on oxygenation in patients with acute respiratory distress syndrome (ARDS) .Methods Twenty-three patients of both sexes (14 males, 9 females) with ARDS (within 72 h after onset of ARDS) were included in this study. The patients ranged in age from 43-78 years. Ten minutes before the patients were placed in prone position, midazolam 2-5 mg was given i. v. followed by continuous infusion at 2-3 mg?h-1 for sedation and a bolus of vecuronium 4 mg per hour for muscle relaxation. The patients were mechanically ventilated (VT 6-8 ml?kg-1, inspiration-time 1.0-1.2 s, RR 12-20 bpm, FiO2 0.4-1.0, PEEP 6-18 cm H2O) . The patients were placed in prone position for 2 h. Radial artery was cannulated and S-G catheter placed. MAP, CVP, MPAP, PAWP, cardiac output, PaO2 , PaCO2 peak inspiratory pressure (PIP) and airway resistance (Raw) were measured and recorded immediately before (T0) and 0.5, 2 h after the patients were placed in prone position (T1 , T2) and 2 h after supine position was resumed(T3) . PaO2/FiO2 and static compliance of the respiratory system (Cst) were calculated. Results In 87% of the patients PaO2/FiO2 was significantly increased during prone position (T1, T2) as compared to the baseline (T0) (P

Objective To evaluate the role of angiocadiography(ACG)in the diagnosis and management of complex/complicated congenital heart disease(CHD).Methods A retrospective study of ACG findings in 360 cases with complex/complicated CHD was performed with a comparision to that of echocardiography(Echo)and related clinical examination.Results The present series of CHD cases included pulmonary atresia with ventricular septal defect in 75 cases,double outlet of right ventricle in 62 cases,Fallot's tetralogy in 60 cases,single ventricle in 52 cases,transposition of the great arteries in 42 cases,tricuspid valve atresia in 15 cases,coronary abnormality in 6 cases,total abnormal pulmonary venous connection in 5 cases,total endocardial cushion defect in 5 cases,persistent truncus arteriosus in 4 cases,pulmonary atresia with normal ventricular septum in 3 cases,other disorders in 7 cases,and postsurgical operation in 24 cases.ACG was superior to that of Echo in demonstrating the abnormalities of systemic,pulmonary,and coronary arteries and their branches of complex/complicated CHD as well as measuring the pressure of pulmonary artery,vein,and systemic-pulmonary collateral vessels.Conclusion In the diagnosis and differential diagnosis of knotty cases with complex and complicated CHD,particularly in the demonstration of full view of systemic,pulmonary,and coronary arterial branches and accurate measurement of pulmonary arterial pressure/resistance,and atrial,ventricular,and systemic arterial pressure,ACG(including DSA)still plays an important and irreplaceable role.