To investigate the cause,pathogenesis,monifestation and treatment of osteoporosis and bonic arthritis.Bonic arthristis was not the osteoposis.Osteoporosis and bonic arthristis may occured simultaneously.In order to treat the conditions correctly,differentiated diagrosis should be noticed clinically.

OBJECTIVE: To explore the way of developing and improving clinical pharmacy. METHODS: According to the experience of specialized clinical pharmacist, the matters that must be resolved were found out in order to probe into suitable resolutions. RESULTS & CONCLUSION: Specialized clinical pharmacist is the direction of developing clinical pharmacist. Clinical pharmacist’s round and consultation obtain achievements, which should be continued. A lot of things should be put into practice including pharmacoeconomics,evidence-based pharmacy, pharmaceutical care to promote the development of clinical pharmacy. Clinical pharmacist should overcome various difficulties and promote rational use of drugs and clinical pharmacy to guarantee the safety of drug use.

23 rabbits were bilaterally vasectomized and investigated for 12 months with 17 normal male rabbits as control. It was found that (1) positive results of leucocyte adhesion inhibition test occured in 43.5% of the vasectomized rabbits and a significant difference of positive rate was found between 10 and 12 monthes after vasectomy, (2) pathomorphological findings in the immune organs of the vasectomized rabbits showed that the lymph tissues proliferated. The pathomorphological findings were found to be in line with the result of leucocyte adhesion inhibition test.

With the aging of the population, the incidence of osteoporotic fractures is increasing year by year, which leads to a heavy burden to society and families. Preventing osteoporotic fractures and re-fractures are critical issues and current challenges in our country. At present, most patients with high risk of osteoporotic fractures are identified in hospitals after fractures. Due to lack of proper understanding of osteoporotic fractures and a comprehensive management system, clinicians only focus on to the treatment of the fracture itself, and pay less attention to the prevention of long-term fractures. Epidemiological data show that in patients with high risk of osteoporotic fracture or those having first fractures, the risk of reoccurring fractures within 2 years is significantly increased, and the risk of death also continues to increase. This is defined as imminent fracture risk, and it is one of the pressing areas that we can and should start to take action in clinic. Taking into considecation of national conditions, this article analyzes current gaps in the risk management of osteoporotic fractures and proposes strategies from aspects of high-risk population identification, treatment, and multidisciplinary cooperation.

Objective:To evaluate the long-term effectiveness of free transfer of Abductor hallucis muscle plus anastomosis of blood vessels and nerves for dynamic reanimation of the established facial paralysis.Methods: Twenty-eight patients who received the above-mentioned treatment during March 1999 to November 2006 were followed up.The follow-up period was 1 to 16 years,with a median period of 4 years.The facial pictures of frontal view were analyzed before and after operation.T-FGS and facial nerve function index(FNFI) were used to evaluate the facial nerve function before and after operation.Meanwhile,the survival of the graft,the width of the face,the scar,and the function of the foot were analyzed and compared.Results: All patients obtained satisfactory symmetric faces in static state and voluntary contraction of the transferred muscles.Twenty-two patients obtained ideal smiling faces.The T-FGS score increased by(27?7.2) points and the score of FNFI increased by(57?10.7)% after transplantation(P

Objective To investigate the insulin resistance and microalbuminuria in the healthy offspring with a family history of essential hypertension,in order to explore the relationship between the genetic factor and early renal injury.Methods 69 healthy offsprings with the family history of essential hypertension were randomly recruited as the observation group,35 healthy offsprings without the family history of essential hypertension were considered as the control group.The consecutive 12-hour urine was collected to detect the urinary albumin,and blood biochemical examination was conducted.Results Plasma levels of triglyceride (TG),total cholesterol (TC),glucose,fasting insulin,and urinary albumin excretion rate were higher in observation group than in the control group [(1.07±0.65) mmol/L vs.(0.79±0.52) mmol/L,(4.83±0.78) mmol/L vs.(4.48±0.63) mmol/L,(5.27±0.73) mmol/L vs.(4.94±0.85) mmol/L,(10.63±3.21) mIU/L vs.(7.72±3.35) mIU/L,(45.6±29.5) μg/min vs.(18.6±11.7) μg/min,t=2.259、2.348、2.093、4.381、5.337,all P＜0.05].Conclusions Insulin resistance and microalbuminuria occur before hypertension in healthy offsprings with the family history of essential hypertension,and the patients are prone to getting early renal damage,which indicates that heredity is a risk factor for chronic kidney disease.

ObjectiveTo investigate theefficacy of transcutaneous acupoint electrical nerve stimulation plus acupoint pressing in treatingheadachesafter ethmoidectomyforchronic nasosinusitis.MethodOne hundred patients withchronic nasosinusitiswho hadundergoneethmoidectomyunder general anesthesia were randomly allocated to treatment and control groups, 50 cases each.The control group received routine treatment (auricular plastertherapy,anti-inflammatoryandhemostatic therapy, andoxygen uptake) and the treatment group, transcutaneous acupoint electrical nerve stimulation plus acupoint pressing in addition.Postoperative headache severities were comparedbetweenthe two groups at 6, 12 and 24 hrs after thebeginningof treatment.ResultHeadaches were relieved more significantly in the treatment group than in thecontrol groupat 6, 12 and 24 hrs, especially at 24 hrs. ConclusionsTranscutaneous acupoint electrical nerve stimulation plus acupointpressing has a marked therapeutic effect on headachesafter paranasal sinus surgeryand cansignificantlyimprove postoperative quality of life in the patients.This treatment is non-invasive and more easily accepted by the patients and canimprovethe operatingefficiency and feasibility.

The technology,of extracting Semen Cassiae from Jueming Jiangzhi Powder was investigated.The perceutages of extra ction and preservation of anthraquinone were used to select the methods of extra ction, concentration and drying of Semen Cassiae. The optimal procedure was set as follows:the large-size powder of Semen Cassiae was extracted with 50% alcohol for three times, then the extracted liquid was concentrated by vacuum evaporati on and finally dried by spraying.

OBJECTIVE:To investigate the internal quality of 31 batches of Compound Glycyrrhiza oral solutions from different manufacturers.METHODS:The contents of Morphine and Guaifenesin in Compound Glycyrrhiza oral solutions were determined by HPLC,and the pH value of the solution was detected as well.RESULTS:Of the total 31 batches of samples,13 was unqualified in Morphine content,1 was unqualified in Guaifenesin content,and 1 was unqualified in pH value.CONCLUSION:The manufacturers should strictly obey the standards recorded in China Pharmacopoeia in respect of quality control to ensure the safety and efficacy of clinical medication.

OBJECTIVE:To deepen clinical pharmacy work and train special clinical pharmacists in the cardiovascular department.METHODS:Clinical pharmacy working mode approved by clinical staff and patients was established for pharmacists by participating in clinical staff's routine work.RESULTS & CONCLUSION:The system of special clinical pharmacists can help improve clinical pharmacists' approval degree and bring their role into full play in drug treatment and pharmaceutical information service.