Objective:To study the feasibility of using MRI in detection and qualitative analysis of atherosclerotic plaque in rabbits.Methods: The atherosclerotic model was established in rabbits with high cholesterol diet.The experimental animals received T_(1)WI,T_(2)WI,PDWI and TOF sequences scanning and B ultrasound examination.Results: The atherosclerotic model was successfully established in rabbits.T_(1)WI,T_(2)WI and PDWI sequences scanning showed thickening of aortal wall and the plaque showed equal,high or low signal intensities,which was in good accordance with the pathological examination results.The atherosclerotic plaques were successfully detected and analyzed by MR and MR had higher accuracy than ultrasound examination.Conclusion: MR can be used for detection of atherosclerotic plaque and for qualitative analysis of the plaque.

Objective To quantify iron deposition in Alzheimer’s disease (AD),amnestic mild cognitive impairment (aMCI), and normal old people using susceptibility weighted imaging (SWI).Methods Sixty participants (22 aMCI,20 AD,18 normal con-trols)underwent conventional magnetic resonance imaging sequences and SWI using axial/oblique coronal sequences.Phase images were used to calculate bilateral iron deposition in 1 8 regions of interest (ROI)of every participant.The radian angle values were cal-culated and compared between the three groups.Results The radian angle value difference was significant between the aMCI and control groups in the left (L)-hippocampus,L-head of the caudate nucleus,R/L-lenticular nucleus ROIs.The radian angle value difference was significant between the AD and aMCI groups in the R/L-cerebellar hemisphere,R/L-hippocampus,R-red nucleus, R/L-thalamus and splenium of corpus callosum ROIs.Pearson correlation coefficients of the mini-mental state examination (MMSE)scores and many ROIs were significant.Conclusion Iron depositions in the hippocampus,head of the caudate nucleus,len-ticular nucleus and thalamus are significantly different between individuals with aMCI,AD and controls.Using SWI to quantify the iron deposition is a useful tool in detecting aMCI and AD.

Objective: To evaluate the effects of the combined radiofrequency (RF) with oral appliance (OA) therapy on obstructive sleep apnea(OSA). Methods: 15 patients with OSA were diagnosed by overnight monitoring of polysomnography(PSG).They all received bi-polar radiofrequency treatment on palate twice.Polysomnography were taken for the patients 6 weeks after the second RF treatment. 10 cases without TMJ disease and periodontal disease with more than 10 teeth on each of maxillae or mandibulae were treated with OA. Reexamination of PSG was taken one month after application of OA.Statistic analyses were made in the measurements of PSG. Results:PSG measurements showed sleep improvement after treatment(P

Although digital subtraction angiography (DSA) has been used as the gold standard for the diagnosis of intracranial aneurysms, its clinical use is somewhat limited by its invasiveness, high medical cost and potential risk of nephrotoxicity. For the past three decades, the magnetic resonance angiography (MRA) techniques have been developed rapidly. As a non-invasive technique with high resolution ability, MRA can replace DSA for the diagnosis of intracranial aneurysms in most clinical situations. The time-of-flight MRA (TOF-MRA) carries a diagnostic sensitivity of up to 98.2%-98.7%for tiny intracranial aneurysms (<5 mm), while the diagnostic sensitivity and specificity of contrast enhanced MRA (CE- MRA) for intracranial aneurysms are as high as 95% - 100% and 73% - 100% respectively. The diagnostic specificity of phase-contrast MRA (PC-MRA) for intracranial aneurysms (> 5 mm) reaches as high as 100%. All the above mentioned MRA techniques can clearly display the intracranial aneurysms although their imaging characteristics and clinical applications are different from each other. This paper aims to make a brief review concerning the principles, clinical applications and recent progress of some MRA techniques.

Objective To investigate the air pollution level and the distribution regularity of air pollutants in Jilin City. Methods Based on the data from air quality automatic monitoring system in environmental protection station in Jilin City from 2001 to 2005, the concentration change of the inhalable particulate matter (PM10), SO2, NO2 and TSP in the air were analyzed with hour, season and year in different functional areas. Results The concentration of SO2, NO2 in atmosphere in winter and summer showed a daily changing with a bimodal curve, which appeared a high value section at 19:00—21:00 and 7:00—8:00. The highest concentration of pollutants appeared in winter, the lowest one in summer. The daily average concentration range of SO2, NO2 and TSP was 0.021-0.045, 0.027-0.046 and 0.300-0.470 mg/m3 respectively from 2001 to 2005 with a descending trend by years. As for the space distribution, the pollution in the industry area was the heaviest. Conclusion The air pollution type in Jilin City is still a coal-burning pollution, the concentration of air pollutants distributes differently with time and space.

Objective To evaluate the clinical effect of Easy Prosthesis D-10 on open preperitoneal groin tension-free hernioplasty.MethodsThe operative time,operation-correlated complications,hospital stay and recent follow-up findings of 63 patients underwent preperitoneal groin tension-free hernioplasty were analyzed from October 2006 to April 2008.ResultsNo case died in perioperative period.The average operative time was(47.6?10.5)minutes.None of incision infection and scrotal hydrocele occurred.The average hospital stay was(7.7?2.1)days.During follow-up period of 6 to 24 months,no recurrence,chronic pain and foreign body sensation were found.ConclusionThe open preperioneal groin tension-free hernioplasty by Easy Prosthesis D-10 is safe and reliable,especially for the inguinal hernia with large hernia ring or defect of transversalis fascia and recurrent hernia.

The effect of dexamethason ( Dex ) on the rabbit platelet aggregation and release was studided. The results were showed that the platelet aggregation and release induced by collagen were inhibited markedly by Dex, TXA2 production of platelets also reduced, but the platelet activation induced by AA was not affected by Dex. The results were further showed that the PLA2 activity was depressed by Dex, and the action of Dex can be antagonized partly by increase of extracellular Ca2+, it suggests that Dex inhibited the activity of PLA2 with the reduction of Ca2+ inflow into cell. The activity of CaM and AC, the production of cAMP and cGMP were not affected by Dex.

This review summarized some hot research fields in pharmacological effects of sinomenine such as anti-inflammatory, immunosuppressive, and anti-tumor effects. In addition to our exploration of its antinociceptive effect, we summarized above-mentioned pharmacological effects of sinomenine and its underly-ing mechanism, in order to provide an evidence for its clinical use.

Objective To study the effect of hand intrinsic muscle exercise on postoperative recovery of fine movement in children with hand injury.Methods From January 2009 to December 2011,64 children with hand injury were randomly divided to exercise group and control group equally.Hand intrinsic muscle exercise and rehabilitative care were conducted in the exercise group while traditional rehabilitative therapies in control group.After 3-month therapy,MMDT(Minnesota Manual Dexterity Test)and PPT(Purdue Pegboard Test)were conducted to evaluate the functional recovery of hands.Result The results of MMDT and PPT were obviously better in the exercise group than in the control group(P<0.01).Conclusion Hand intrinsic muscle exercise may be effectively in promoting the recovery of fine movement in children with hand injury.

Objective To investigate the changes of soft and hard tissues after extraction space closure with micro-screw implant as orthodontic anchorage. Methods Twenty cases were selected randomly with the first premolars extraction. Micro-screw implant was used as orthodontic anchorage. Sliding technique was used to close the extraction space. The lateral cephalograms before and after the treatment were evaluated.Results The upper incisors moved 7. 15 mm palatelly, 1. 63 mm intruded. The upper first molar moved 0. 80 mm distally, 1. 80 mm intruded. The lower incisors moved 4. 65 mm distally, 0.48 mm extruded. The lower first molar moved 0. 18 mm mesially, 1.18 mm extruded. A point, B point, upper lip, lower lip showed distal movement. Conclusions Micro-screw implant can provide acceptable and reliable anchorage in the process of extraction space closure, and improve the profile. Besides, it produces skeletal change on the maxilla.