1.The effects of the accessory deep peroneal nerve on the diagnosis of the deep peroneal nerve injury
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(08):-
Objective To study the effects of the accessory deep peroneal nerve,an anomalous branch of the superficial peroneal nerve, on the diagnosis of the deep peroneal nerve injuries. Methods Ten cases (7 male, 3 female, mean age 32.8 years) of deep peroneal nerve injuries with the presence of accessory deep peroneal nerve were examined in this study. All the cases were reviewed and analyzed with regard to the basic anatomy, clinical symptoms, electrophysiological data and diagnosis. Results In the presence of the accessory deep peroneal nerve, the lesions of the deep peroneal nerve spare the function of the lateral portion or the whole of the the extensor digitorum brevis (EDB) muscle. It may result in an unconformity of the severity of lesion and its clinical symptoms as well as the electrophysiological findings. Conclusion Knowledge of this anomaly is of crucial importance in the clinical evaluation of nerve injuries of deep peroneal nerve, as well as in avoiding errors in interpreting the electrophysiological data of this nerve.
2.The effect of Riche-Cannieu anastomosis on the diagnosis of patients with carpal tunnel syndrome
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(12):-
Objective To study the effect of the Riche-Cannieu anastomosis, an anomalous anastomosis between the deep branch of ulnar nerve and the recurrent branch of median nerve in the palm of the hand, on the diagnosis of patients with carpal tunnel syndrome. Methods Twelve patients (2 male, 10 female, mean age 49.8 years) with carpal tunnel syndrome with the presence of Riche-Cannieu anastomosis were tested in this study. Their clinical data including the symptoms and signs, electrophysiological findings and diagnosis were collected and discussed in relation to an anatomical review of these nerves. Results Due to the existence of the Riche-Cannieu anastomosis, the patients with carpal tunnel syndrome spared part or all of the function of the abductor pollicis brevis (APB) muscle. It may result in an unconformity of the patients′lesion degree caused by carpal tunnel syndrome and its clinical symptoms and electrophysiological findings. Conclusion Knowledge of the Riche-Cannieu anastomosis is of crucial importance in the clinical evaluation, diagnosis and treatment of carpal tunnel syndrome, as well as in avoiding errors in interpreting the electrophysiological data of the patients.
3.Experimental Study on Yisheng Injection for Reducing Cold Ischemia Injury in Isolated Rat Heart
Journal of Chongqing Medical University 2003;0(06):-
Objective;To investigate whether the traditional Chinese medicine Yisheng Injection can reduce the injury on isolated rat heart induced by cold ischemia. Methods ;18 isolated female closed colony SD rats were divided into two groups at random. In the control group, the isolated rat hearts were preserved in 0.9% sodium chlorine solution at 4℃ , while in the experimental group ,the hearts were preserved in 0.9% sodium chlorine solution containing Yisheng injection at 4℃. The specimens were harvested 2,6,12, 24,48 and 72 hours after preservation. Histochemical changes were observed in two groups. Results ;In the control group, the activities of alkaline phosphatase ( ALP) and NADPH diaphorase (NADPHD) decreased after cold ischemia for 24 hours. Lactic dehydro-genase (LDH) decreased slightly, while ALP and NADPHD decreased evidently, after cold ischemia for 48 hours. Succinic dehydro-genase ( SDH) and cytochrome oxidase ( CCO) decreased slightly, and NADPHD disappeared after cold ischemia for 72 hours respectively. In the experimental group, NADPHD, LDH and CCO decreased slightly after cold ischemia for 24, 48 and 72 hours. ALP decreased slightly after cold ischemia for 48 hours, however, SDH showed no changes, after cold ischemia for 72 hours. Conclusion : Cold ischemia can induce cold ischemia injury in isolated rat hearts, especially the vascular endothelial cells being more sensitive. Yisheng injection can reduce this kind of injury to some degree.
4.Simultaneous Determination of Oleanic Acid and Ursolic Acid in Salvia Plebeia R. Br. from Different Ori-gins by HPLC
China Pharmacist 2016;19(9):1776-1777,1780
Objective:To develop an HPLC method for the simultaneous determination of oleanic acid and ursolic acid in Salvia plebeia R. Br. from different origins. Methods:The column was Agilent-C18 (250 mm × 4. 6 mm,5μm) with the temperature of 25℃, the mobile phase was methanol-water-glacial acetic acid-triethylamine (90 ∶10 ∶0. 03∶0. 06) at the flow rate of 1. 0 ml·min-1 ,and the detection wavelength was 210 nm. Results: The calibration curves were linear within the range of 7. 50-75. 00 μg · ml-1 for oleanic acid(r=0. 999 7)and 5. 00-50. 00 μg · ml-1 for ursolic acid(r=0. 999 7). The average recovery of oleanic acid and ursolic acid was 100. 15%(RSD=1. 14%,n=6)and 99. 40%(RSD=1. 67%,n=6), respectively. Conclusion: The method is simple and accurate, which is suitable for the determination of oleanic acid and ursolic acid in Salvia plebeia R. Br. from different origins.
5.Observation on the therapeutic efficacy of budesonide and compound ipratropium bromide inhalated in treatment of infant bronchiolitis
Chinese Journal of Primary Medicine and Pharmacy 2008;15(12):2011-2012
Objective To discuss the therapeutic efficacy of budesonide and compound ipratropium bromide inhalated in treatment of infant bronchiolitis.Methods From January 2005 to February 2007,150 infants with bronchiolitis were randomly divided into treated group and control group.Both the two groups were treated with comprehensive treatment and antiviral therapy;control group were treated with budesonide suspemion and compound ipratropium bromide inhalated.Clinical efficacy of both two groups was evaluated.Results Cure rate of treatment group was 91%,cure rate of control group was 71%,the clinical therapeutic efficacy were compared between the two groups,the difference of which had statistical significance.Conclusion The result of experiment indicates that the therapeutic efficacy of budesonide and compound ipratropium bromide inhalated in treatment of infant bronchiolitis is better method.
6.Study on therapy of Famotidine combined with Hemocoagulase in neonatal stress ulcer complicating upper gastrointestinal hemorrhage
Chinese Pediatric Emergency Medicine 2007;14(z1):25-26
Objective To observe the therapeutic effect of Famotidine combined with Hemocoagulase treating the neonatal stress ulcer complicating upper gastrointestinal hemorrhage. Methods 72 patients of stress ulcer complicating upper gastrointestinal hemorrhage were randomly divided into two groups:study group(35 cases) were treated with Famotidine plus Hemocoagulase;control group(37 cases)were cured by Famontidine only. The different therapeutic effects were compared. Results 35 cases of study group(100%)and 28 cases of control group(75.68%) were cured successfully. Compared the excellent rate of study group and control group,the former was significantly higher than the latter(P<0.01). Conclusion Famotidine combined with Hemocoagulase treating the neonatal stress ulcer complicating upper gastrointestinal hemorrhage has notable therapeutic effect.
7.Vitamin D and systemic lupus erythematosus
International Journal of Pediatrics 2015;42(3):284-287
Vitamin D is a steroid hormone that exerts its action by binding to the vitamin D receptor.In addition to its actions on calcium and phosphate metabolism,it exhibits a plethora of regulatory effects on proliferation,dfferentation and function of the cells of the immune system,thus play an important role in the regulation of the immune response.Systemic lupus erythematosus (SLE) is a multisystemic auto-Immune disease that is characterized by a number of autoantibodies.VitD and VDR can inhibit the activation of autoreactive lymphocyte and the production of auto-antibodies,thus play an important role in the development and mechanism of SLE.Supplementation of VitD may improve the progrosis of SLE.
8.Improving Clinical Medical Teaching Level by Learning from the Experience of Advanced Countries
Chinese Journal of Medical Education Research 2003;0(03):-
The article points out that to improve the teaching quality and level of national medical colleges and universities,the experience of Medical College of Monpillier University,France should be introduced and learned from.Views and suggestions are also put forward to counter the existing problem in national medical teaching system and clinical practices.
9.Assessment the value of serum Lp-PLA2,hs-CRP and D-D dimer on the severity of coronary artery lesion of coronary heart disease
Chongqing Medicine 2015;(9):1215-1217,1220
Objective To investigate the assessment value of serum Lp-PLA2 ,hs-CRP and D-D dimer on the severity of cor-onary artery lesion .Methods A total of 136 patients with coronary heart disease acute myocardial infarction (AMI) group 46 ca-ses ,stable angina pectoris (SAP) group 38 cases and unstable angina pectoris (UAP) group 52 cases from the inpatient of cardiolo-gy department in our hospital were selected as observation group ,and 135 healthy subjects were selected as control group ,serum Lp-PLA2 was detected by enzyme kinetic method ,Serum hs-CRP and plasma D-D dimer were detected by immune turbidimetric method ,of the severity of coronary artery lesion was evaluated by the Gensini integrations .Results Serum Lp-PLA2 ,hs-CRP ,D-D dimer level and Gensini score of observation group were significantly higher than those of control group ,above indexes of AMI group were higher than those of SAP group and UAP group ,UAP group were significantly higher than SAP group ,with statistical significance between the two groups(P<0 .05) .Serum Lp-PLA2 ,hs-CRP ,D-D dimer level and Gensini score of patients with heart functional class Ⅱwere significantly lower than those of Ⅲ and Ⅳ patients ,above indexes of patients with heart functional class Ⅲwere significantly lower than Ⅳ patients ,the difference between two groups was significant(P<0 .05) .Compared with severity of coronary artery lesion ,serum Lp-PLA2 hs-CRP and D-D dimer levels of mild coronary artery lesions were significantly lower than those of moderate and high coronary artery lesions ,and moderate coronary artery lesions was obviously lower than high coronary artery lesions (P<0 .05) ,Pearson correlation analysis also found that ,Lp-PLA2 ,hs-CRP ,D-D dimer levels had positive correlation with Gensini score (r=0 .642 ,0 .651 ,0 .608 ,P<0 .05) .Conclusion The assessment of serum Lp-PLA2 ,hs-CRP and D-D dimer level in the severity of coronary artery lesion has important significance .
10.Experience of professor LI De-lin in treating diabetes mellitus
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(04):-
Professor LI De-lin is sophisticated in the clinical experiences of treating diabetes mellitus(DM)with traditional Chinese medicine(TCM).Based on clinical observations for many years,the key pathogenesis of DM resulted from internal organs'deficiency,endogenous heat exuberance,liquid and qi's consumption as well as blood density and turbid fluid thickness.From the knowledge above,professor LI advocated to treat DM and diseases accompanied by it with the combination of treatment based on disease and syndrome differentiation to improve the curative effects.During the specific treatments,professor LI emphasized that treatment based on disease differentiation should benefit qi,nourish yin and strengthen yang;treatment based on syndrome differentiation should strengthen vital qi and eliminate pathogenic factor.Strengthening vital qi includes to benefit qi ,nourish blood,tonify yang and supply yin.Eliminating pathogen includes to treat heat-toxicity,phlegm,dampness and depression at the same time.He advocated firstly to invigorate spleen and kidney,secondly to clear heat fire and disperse stagnated liver qi,lastly to moisten and invigorate lung.We received satisfactory curative effects both on the clinical treatments and experiments in DM and diseases accompanied by it when adopting the TCM methods of treatment based on the theory by Professor LI De-lin.