OBJECTIVE To explore the causes, predilection sites and treatment of nasal sinus mucoceles after hypophysectomy.METHODS The clinical data of 7 cases with nasal sinus mucoceles after hypophysectomy diagnosed and treated in our Department from Jan.1998 to Aug.2007 were retrospectively studied.RESULTS The mucoceles were located at ethmoid sinus in 2 cases,frontal sinus in 2 cases,frontal and ethmoid sinuses in 3 cases.All of the 7 cases underwent mucocelectomy under nasal endoscope or a combined endoscopic intranasal and extra-nasal approach.No recurrence was found after follow up for 1 to 3 years.CONCLUSION The causes of nasal sinus mucoceles after hypophysectomy are the change of the anatomic structure of nasal cavity after surgery.The stenosis,adhesion of middle nasal meatus or obstruction of the sinus ostium are found in all the patients.Intranasal endoscopic surgery or combined with extra-nasal approach is the first choice for nasal sinus mucoceles.

Adolescent ; Adult ; Barotrauma ; complications ; Female ; Humans ; Male ; Middle Aged ; Occupational Diseases ; etiology ; therapy ; Sinusitis ; etiology ; therapy ; Young Adult

Objective:To observe the clinical efficacy of Pingxiao capsules in the treatment of benign thyroid nodules. Methods:Totally 240 patients with benign thyroid nodules were randomly divided into the treatment group and the control group with 120 ones in each. The control group received levothyroxine at low dose, the treatment group received Pingxiao capsules, and the treatment course was 3 months. The type B ultrasonic inspection and lab inspection ( for thyroid hormones and blood lipid) were carried out, the cura-tive effect was compared and the adverse reactions were recorded as well. Results:Three patients in the treatment group and five ones in the control group were lost during the follow-up. After the treatment, the max diameter of thyroid nodule and the thyroid volume de-creased in both groups (P<0. 05), and those in the treatment group were smaller than those in the control group (P<0. 05). The levels of TSH and TC in the control group decreased after the treatment, which were significantly lower than those in the treatment group (P<0. 05). The total effective rate in the treatment group was higher than that in the control group, and the incidence of ad-verse reactions was lower than that in the control group, and both had significant differences between the groups (P<0. 05). Conclu-sion:Pingxiao capsules are effective and safe in the treatment of benign thyroid nodules.

Objective:To investigate effectiveness of exposure and ritual prevention of patients with obsession-compul-sive disorder(OCD),so as to provide references for professionals in clinical psychology.Methods:One female patient with severe OCD received 3 weeks intensive exposure and ritual prevention treatment.In order to investigate the effectiveness,she completed Symptom Check List 90 and Yale Brown Obsessive Compulsive Scale(SCL-90 and YBOCS) at pre-treat-ment,mid-treatment and post-treatment.Results:After treatment,the patient's scores of questionnaires reduced,such as score on YBOCS reduced from 38 to 9.She reported that her washing time reduced obviously and her own measure of dis-tress index reduced.Conclusion:Exposure and ritual prevention could treat the patient with OCD effectively.Her distress reduced and life function was improved.

Based on the state of the development of the body and the subcutaneous fat of 4314 students (includidg boys and girls) at four middle schools in Zibo City, the fat was appraised and analyzed by the body-block indexand the thickness of the subcutaneous fat. The stand-ard-proposal value was also put forward by using y+1.645 Sy.x as the dividing-line value of the groups of different ages and the fat of both sexes. The comparison with foreign standards concerned showed that tally rate of the musculus triceps brachii and the shoulder-blade region of the fat sufferers was 76.87% and 51.7%. The tally rate of the sum of the above two terms reached 100% among the male and the female groups, from 15 to 18 years old. According to the current appraisable standard, the rate of fat children and juvenile for male was 2.86%, while for female, 4.0%. It was obvious that the rate of occurrence for female is higher than that for male(P

BACKGROUND:In the whole world, spinal cord injuries caused by trauma lead to more than 180 000 people presenting with permanent impairment annualy. A large number of experiments have confirmed in recent years, under physiological conditions, microRNA has specific expression and plays an important role in the nervous system. OBJECTIVE: To discuss the changes in microRNA expression induced by injuries as wel as the pathophysiological significance in spinal cord injury, and to explore the development potential of microRNA in tissue-engineered and clinical repair of spinal cord injury. METHODS:A computer-based search of PubMed and Chinese Journal Database was performed for related articles published from January 2000 to December 2014 using the keywords of “SCI, microRNA, transcriptional control, clinical research progress” in English and Chinese. Finaly, 38 articles were included for result analysis. RESULTS AND CONCLUSION: Mechanical injury initialy triggers a series of complex secondary damages, including nervous, vascular and immune systems, which can influence the severity of spinal cord injury to a great extent. Secondary damage to the spinal cord is mainly attributed to the activation and deactivation of some specific genes associated with celular and biochemical mechanisms, such as cysteine aspartate specific protease (caspase) gene family, apoptosis related protein Fas and its ligand Fasl system, P53 gene, apoptosis related gene Bcl-2 family. Recent studies have proved that the functional activation of microRNA expression is the key to spinal cord injury. With the development of biological information engineering, studies and controling technologies associated with microRNA expression have been gradualy dominated, some clinical application based on microRNA technology has entered the clinical trial stage. It is believed that with the continuous development of technology and decrease of cost, permanent dysfunction due to spinal cord injury can be regulated and repaired through the microRNA technology at gene level in the future.

Fire-dragon moxibustion is a modified moxibustion method based on the traditional moxibustion therapy. It’s more easy-to-operate, has higher security, and is more significant in supplementing yang qi. Via extensive and intensive hot stimulation, fire-dragon moxibustion can activate yang qi inside human body, regulate Zang-fu organs, modulate immune function, and finally achieve the goal of preventing and treating diseases.

Objective:To investigate the differences of Ego Impairment Index (EII)of Rorschach test be-tween patients with schizophrenia and normal individuals.Methods:Totally 60 patients with schizophrenia (17-53 years old)meeting the criteria of Diagnostic and Statistical Manual of Mental Disorders,Fourth Edition (DSM-IV) and 60 age-and gender-matched normal subjects were involved in this study.The Rorschach ink blots test was used in both patients and normal subjects.The Ego Impairment Index (EII)of all the participants were calculated on the basis of their responses to the Rorschach ink blots test.The EII and the subcomponents of it (including distorted form quality,weighted sum of cognitive processing errors,distorted perceptions of human movement,critical con-tent,good human representation,and poor human representation)of the two samples were compared to explore EII's discrimination to patients and normal individuals.Results:The score of EII [(0.7 ± 1.7 )vs. (-0.9 ± 0.9 )],distorted form quality [(6.2 ± 2.3 )vs. (3.4 ± 2.6 )],weighted sum of cognitive processing errors [(14.0 ±6.5)vs.(7.2 ±4.2)],distorted perceptions of human movement [(0.7 ±1.2)vs.(0.3 ±0.7)], and poor human representation [(3.1 ±2.7)vs.(1.8 ±1.8)]were higher in patients than in normal participants (Ps<0.05 ).No significant differences were found for the score of good human representation and critical content between the two groups (Ps>0.05 ).The result of Diagnostic Test showed that when EII equaling to -0.5 ,the sensitivity,specificity,and Youden Index of it to distinguish patients from normal individuals were 0.9 1 ,0.75 ,and 0.66 respectively.Conclusion:It suggests that the ego functions of patients with schizophrenia have become serious damage compared with normal individuals.The EII of Rorschach test has high sensitivity while relatively low speci-ficity in discriminating patients with schizophrenia,which needs to be further perfected.

OBJECTIVE:To discuss the application of Prescription Automatic Screening System (PASS) in the examination of clinical medical orders. METHODS: The level and type of caution and the modification rate of medical orders in our hospital between April 2005 and April 2006 were analysed statistically, and the conformity between PASS cautions of medical orders and clinical medications was evaluated. RESULTS: A total of 10 982 160 medical orders were monitored by PASS, of which, 11 146 were with black cautions and in which 2 861(25.67%) were modified, 51 504 were with red cautions and in which 10 357 (20.0%) were modified, 339 449 were with yellow ones and in which 66 022 (19.45%) were modified. In PASS monitor process, inconformity between feasible clinical medical orders and cautions of PASS was noted in a few cases. CONCLUSION: The examination of medical orders using PASS is convenient and rapid and the PASS can help improve clinical rational drug use level, however, its function of remains to be updated and optimized.

Purpose To study the value of the ultrasonic imaging in the diagnosis and differential diagnosis of benign and malignant breast tumor. Methods Color doppler ultrasound examination were conducted in 262 cases of patients with breast tumor. The mor-phology of the tumor, edge, envelope, internal echo, microcalcification, length and breadth ratio, axillary lymph node and blood-flow signals of color doppler in breast tumors were observed and these results were compared with the pathological observation postoperation. Results There were 314 tumors in all cases, the coincidence rate in the diagnosis of benign breast diseases with ultrasonic imaging and pathological diagnosis was 97. 3%, the misdiagnosis rate was 2. 7%. The coincidence rate in the diagnosis of breast malignant tumors with ultrasound imaging and pathological diagnosis was 92. 9%, the misdiagnosis rate was 7. 1%. There were statistically signif-icant differences between benign tumors and malignant tumors in the tumor shape, edge, echo, microcalcification, length and breadth ratio, axillary lymph node imaging characteristics (P<0. 01). Conclusion Ultrasound imaging can be more accurate diagnosis and i-dentification of benign and malignant breast tumors.