This paper introduced the risk communication principles made by WHO including: establishing trust, releasing information betimes, keeping transparent , listening to the public opinions and involving them in etc.Seven steps to make a two -way and interactive communication are also put up on that basis .It covers infor-ming the medial information and comforting patients ’ anxiety.In addition, the strategies of informing the patients of high-risk medical issues or low -risk medical issues and good or bad news are also mentioned .

Objective The purpose of this study is to investigate CD 46 expression in advanced invasive breast cancer and in normal breast tissues , and to analyze the correlation between CD 4 expression and effect of neoadjuvant chemotherapy ,exploring its clinical significance for the prognostic value of neoadjuvant chemotherapy in breast cancer .Methods Immunohistochemistry was employed to detect CD 46 expression of tissue samples from 60 patients with invasive breast cancer and 30 normal breasts .We further analyzed the relationship between effect of neoadjuvant chemotherapy and CD 46 expression ,and the prognostic significance for the survival .Rseults CD46-positive rate in breast cancer was apparently higher than that in normal breast tissues (81.67% vs. 46.67%,P<0.05).After neoadjuvant chemotherapy,the CD46 expression was significantly decreased (P <0 .05).There was a negative correlation between CD 46 expression and efficacy of chemotherapy ( P<0.05). CD46 expression in breast cancer could be affected in cancer invasion ,lymph node metastasis(P<0.05).Con-clusion CD46 expression in breast cancer patients is higher than that in healthy people ,and was negatively cor-related with efficacy of adjuvant chemotherapy .The increasing rate of CD 46 positive expression has predictive val-ue for the poor prognosis of patients .

Objective To compare the efficacy of two different surgery incisions on original corneal astigmatism in cataract surgery. Methods 300 patients (300 eyes) of cataract surgery from August 2012 to August 2013 in our hospital were included in the study,of which 150 patients in the observation group treated with transparent cornea incision in the steep axis of astigmatism,and the control group of 150 pa-tients received lateral ( right) or on the nose by the temporal side ( left) transparent cornea incision. Results In the third day,first month, third month,sixth month and 12th month after surgery,the average corneal astigmatism in the observation group was significantly lower than that before the surgery,which after a month the lowest ( +0. 79 ± 0. 92)D;average corneal astigmatism of patients in the control group were significantly higher than that before the surgery,corneal astigmatism after 3 days to reach the highest,( -5. 65 ± 0. 89)D,3 days after sur-gery,1 month, 3 months, 6 months and 12 months,patients in the observation group were significantly higher visual acuity patients,the differ-ence was statistically significant (P<0. 05). Conclusion Phacoemulsification clear corneal incision along the steep axis IOL implantation for cataract surgery can correct astigmatism original extent a certain extent,and to promote the recovery of visual acuity in patients with a grea-ter degree.

Exterior-and interior-meridian acupoints were used, mainly by selection of local acupoints along meridian. According to the state of disease, electroacupuncture and acupoint injection were combined to treat brachial plexus injury. Among 12 patients, 6 cases were basically cured, 4 cases got effectiveness and 2 cases had no effectiveness. The therapeutic effect of exterior- and interior-meridian acupoints in brachial plexus injury was satisfactory.

Objective To discuss the change and the regulation of tumornecrosis factor(TNF-?) and epidermal growth factor(EGF) before and after extracorporeal shock wave lithotripsy.Method Radioimmunoassay was used to measure TNF-? in 50 cases urine sample before and after ESWL.Results TNF-? level in urine after ESWL were increased significantly at 1～4d(t=2.82,P

Objective To compare the content of total flavonoids in Herba Scutellarlae Barbatae derived from different places.Method UV metric method was used to determine the contents of total flavonoids of Herba Scutellarlae Barbatae from different regions.Result The contents of total flavonoids in Herba Scutellariae Barbatae derived from Nantong Jiangsu,Juaoling Guangdong,Lixin Anhui,Huaning Hunan, Mojiang Yunnan,Yongding Fujian,Nanchang Jiangxi,Longsheng Guangxi,Honghu Hubei and Qingyuan Zhejiang were 4.16%,3.55%,2.89%,2.78%,2.41%,2.22%,2.16%,1.98%,1.61% and 1.51%,respectively. Conclusion The content of total flavonoids in Herba Scutellariae Barbatae from different places is quite different,and the highest is the one from Nantong Jiangsu.

OBJECTIVE: To discuss the transnational management strategy of traditional Chinese medicine(TCM) enterprises in China.METHODS: The actuality of the transnational management of TCM enterprises and the main difficulties encountered by them were analyzed.RESULTS: The problems such as foreigners' different opinions on TCM,the laws,intellectual property rights and technology faced by TCM enterprises hindered the practice of the strategy of transnational management.CONCLUSION: The TCM enterprises in China should rely on special advantages in TCM to cultivate the ownership advantages,regional advantage and internalization advantage so as to effectuate transnational management.

OBJECTIVE: To promote Chinese pharmaceutical enterprises to understand their social responsibility clearly and to fulfill it actively.METHODS: The category of social responsibility of pharmaceutical enterprises was analyzed as well as the main approaches to perform corporate social responsibility.RESULTS: Chinese pharmaceutical enterprises should figure out their responsibility to consumers,employees,investors,society,community and other stakeholders.In recent years,the approaches to perform social responsibility based on force system of law and regulations and the improvement of enterprises' consciousness.These are unfavorable to Chinese pharmaceutical enterprises to undertake social responsibility actively.CONCLUSION: There are two approaches to promote Chinese pharmaceutical enterprises to perform their social responsibility,which are external supervision and internal governance.

Objective To present a new seriological method for diagnosing breast carcinoma.Methods Seral anti-p53 antibody was detected with immuno-polymerase chain reation(Immuno-PCR).The expression of p53 in tissue was detected with enzymeimmu-nohistochemistry technique.Results The positive rate of anti-p53 antibody in serum of breast carcinoma was 39.5% and anti-p53 antibody was not found in non-carcinoma and normal controls.The positive rate of anti-p53 antibody was higher than that of non-carcinoma and normal controls(P

AIM: To observe the adverse effect and clinical efficiency of Y-shape plate internal fixation for treating comminuted distal humeral fracture. METHODS: A retrospective analysis was conducted in 18 patients with the comminuted distal humeral fracture,who were admitted in the First Affiliated Hospital of Nanyang Medical College from January 2003 to December 2006. All patients were treated with Y-shape stainless steel or Ti-alloy plate in 3-7 holes,then the response of materials and host was observed. The curative efficiency was assayed with Cassebaum score,and the healing of fractures was detected with X-ray film. During follow-ups,the pain and joint motion were observed. RESULTS: The mean operational time was 134 minutes,the mean value of intraoperative blood loss was 172 mL,and all the incisions were healed well. All the patients were followed up for 6 months,and the mean time for the fracture healing was 14 weeks. One case appeared delayed healing in the resection lesion,and Kirschner's wire was loosened in 2 cases. There was no infection,local inflammatory reaction or rejection reaction occurred. Among 18 patients,11 got excellent results,4 good,2 fair,1 poor,and the rate of excellent and good efficiency was 83.3%. CONCLUSION: Y-shape plate after implantation shows good biocompatibility with the human body,with the manifestations of good reduction of comminuted distal humeral fracture,firm internal fixation,and satisfactory functional recovery of elbow joint.