1.Effect of different respiratory mask pressure on upper airway volume
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(08):-
OBJECTIVE To investigate the effect of different respiratory mask pressure on the upper airway volume(UAV),and to compare the changes of UAV between patients with obstructive sleep apnea hypopnea syndrome(OSAHS)and normal adults. METHODS Thirty three patients with OSAHS and thirty normal adults were included in this study.CT scan evaluated the UAV from roof of nasopharynx to glottis.UAV under different respiratory mask pressure between patients with OSAHS and normal adults were compared.RESULTS Patients with OSAHS had less UAV,and changes of UAV per cmH_2O were significantly smaller in patients with OSAHS than normal adults.CONCLUSION The results suggest that the quantitative data of UAV and changes of UAV per cmH_2O can be obtained.Upper airway anatomic narrowing and reduced airway distensible degree are major etiological factors for OSAHS.
2.The Impact of Latin on the formation and development of English for medical purpose (EMP)
Chinese Journal of Medical Education Research 2006;0(08):-
This paper aims to elucidate the great impact of Latin, one of the most ancient languages, on the formation and development of English for Medical Purpose(EMP)from the historical point of view, and meanwhile provides it with detailed evidence in phonetic, lexical and grammatical respects.
3.Distribution of nitric oxide synthase positive neurons in spinal cord of rats with cirrhosis
Chinese Journal of Tissue Engineering Research 2005;9(37):178-179
BACKGROUND: Cirrhosis can cause severe effect on spinal cord or other tissue and organ sometimes.OBJECTIVE: To establish cirrhosis model with rat liver injured by tetrachloride so as to investigate the distribution of nitric oxide synthase (NOS)in spinal cord of rats with cirrhosis.DESIGN: Completely randomized controlled study.SETTING: Anatomy Department of Capital University of Medical Sciences.MATERIALS: The experiment was completed at the Anatomy Department of Capital University of Medical Sciences from March 2002 to December 2003. Totally 20 male Wistar rats were divided randomly into cirrhosis group and normal group with 10 in each group.METHODS: Cirrhosis model in cirrhosis group was established with rat liver injured by tetrachloride, but rats in normal group were not treated with any method. After 3 months, total rats in the two groups were perfused and fixed; meanwhile, tissue of spinal cord was taken out for section.Quantity and gray degree of NOS positive cell in spinal cord of rats with cirrhosis were measured with nicotinamide adenine dinucleotide hydrogen phosphate-diaphorase (NADHP-d) histochemical method and Leica Q500IW image analysis system.MAIN OUTCOME MEASURES: [1] Gray degree of NOS positive neurons of rats in the two groups; [2] Distribution of NOS positive cell of rats in the two groups.RESULTS: Twenty rats all entered the final analysis. [1] Gray degree of NOS positive neurons of rats in the two groups was 60 (P > 0.05). [2] In the area of gray matter of spinal cord, NOS positive cells were mainly distributed over the circumference of central canal, i.e. the Ⅹ layer of spinal cord and intermediolateral nucleus. Color of NADHP-d was positive, and the cellular form was shaped in triangle and fusiform. Cellular nucleus was not colored but color of cytoplasm was deep. The size of cells was moderate mainly of 25 μm. NOS positive cells were generally distributed averagely over intermediate zone of gray matter in cervical, thoracic and lumbar spinal cord and had no specific changes.CONCLUSION: Expression of NOS in spinal cord of rats in the cirrhosis group and the normal group is probably identical. Distributive characteristics of nitrogen monoxide (NO) in spinal cord suggest that adjustment on low sympathetic nerve of rats with cirrhosis is not different from that of the normal.
4.The Study Paradigm of Executive Function on Memory Updating
Chinese Medical Ethics 1995;0(02):-
Executive function is an important advanced cognitive process, and it is the function that integrates different cognitive processes to achieve one's aim. Updating is an important component of executive function. According to the classifications of Miyake & Colletee on executive function, two study paradigms on memory updating are discussed: n-back paradigm & running memory paradigm. A new study method called latent variable analysis and new studies of cognitive neuroscience on memory updating are introduced. Issues on ethics and morality in research on cognitive experiment of psychology are briefly demonstrated to explore appropriate direction for research of executive function in future.
5.The Relationship between Serum Uric Acid and Clinic Characteristics and Result of Coronary Artery Angiography of Patients with Coronary Heart Disease
Journal of Medical Research 2006;0(02):-
Objective To investigate the relationship between serum uric acid(SUA)and clinic characteristics and result of coronary artery angiography of patients with coronary heart disease(CHD).Methods Two hundreds and seven patients for coronary artery angiography were divided into CHD group and control group.Their clinical data and results of coronary artery angiography were analyzed through statistics.Results SUA levels of CHD patients were significantly higher than the control subjects SUA(P
6.Application of combination detection of CA15-3, CEA, COX-2 on diagnosis of breast carcinoma
Cancer Research and Clinic 2013;(1):44-46
Objective To investigate the value of combination detection of CA15-3,CEA,COX-2 on early diagnosis of breast carcinoma.Methods 68 breast cancer patients,61 benign breast disease patients and 68 healthies were selected.Serum levels of COX-2 were detected by ELISA technique,CA15-3 and CEA levels were detected by electroche-miluminescence technique.Results Serum levels of CA15-3,CEA,COX-2 in breast carcinoma group were (34.67±13.20) U/ml,(7.38±3.87) ng/ml,(43.25±10.87) ng/ml.Their levels were higher than those in benign breast disease group and healthy group,the differences were significant (P < 0.01).In combination detection,the sensitivity was 84.9 %,and accuracy was 91.2 %,which were higher than single tumor marker used in breast cancer diagnosis.Conclusion The combined detection of CA15-3,CEA,COX-2 could increase the diagnosis rate of breast carcinoma.
7.Investigation on Causes of False-negative 14 C-Urea Breath Test
Chinese Journal of Gastroenterology 2015;(3):151-154
Background:14 C-urea breath test(14 C-UBT)is widely used for diagnosis of Helicobacter pylori(Hp)infection owing to its noninvasiveness and high sensitivity and specificity. Nevertheless,the presence of false-negative result can influence the diagnostic accuracy. Aims:To investigate the possible causes of false-negative 14 C-UBT for improving the accuracy of diagnosis. Methods:Eight-two cases with confirmed false-negative 14 C-UBT and 813 controls with true-positive 14 C-UBT at the People’s Hospital of Xinjiang Uygur Autonomous Region from Jan. 2014 to Aug. 2014 were enrolled. Patients in both groups were diagnosed as positive for Hp infection by Warthin-Starry silver staining combined with Hp stool antigen test. Univariate and multivariate analysis were performed to screen the factors related with false-negative 14 C-UBT. Results:In univariate analysis,5 variables were significantly different between case group and control group(P ﹤ 0. 05),and were taken into the multivariate analysis. Logistic stepwise regression analysis revealed that bile reflux( OR = 3. 961,P ﹤0. 001),post subtotal gastrectomy(OR = 9. 734,P ﹤ 0. 001),type Ⅱ Hp infection(OR = 1. 892,P = 0. 012)and upper gastrointestinal bleeding( OR = 4. 979,P ﹤ 0. 001 ) were the independent risk factors for false-negative 14 C-UBT. Conclusions:Bile reflux,upper gastrointestinal bleeding,post subtotal gastrectomy and type Ⅱ Hp infection might be the influential factors for false-negative 14 C-UBT. Combined tests for Hp infection should be suggested in patients with negative 14 C-UBT who had undergone subtotal gastrectomy or complicated with bile reflux or upper gastrointestinal bleeding.
8.Clinical evaluation of rectal cancer after neoadjuvant chemoradio-therapy
Chinese Journal of Clinical Oncology 2015;(6):360-362
Rectal cancer is a common type of malignant tumor, with increasing incidence over the previous years. Total mesorec-tal excision is the most important treatment for rectal cancer. Advanced rectal cancer presents high local recurrence rate and low sphinc-ter preservation rate. For locally advanced rectal cancer, neoadjuvant chemoradiotherapy is the optimal management strategy. In this re-gard, clinicians have focused on investigating the clinical effects of rectal cancer after neoadjuvant chemoradiotherapy. Prediction and evaluation of rectal cancer after neoadjuvant therapy can be used to determine further necessary treatments, effect on quality of life, and survival time of patients.
9.Comparison of effects of cefepime, ceftazidime and cefathiamidine on bacterial infection in gynecology
Chinese Journal of Primary Medicine and Pharmacy 2015;(6):870-872
Objective To evaluate the efficacy and safety of domestic cefepime ,ceftazidime and cefathiami-dine on bacterial infection in gynecology .Methods 460 patients were randomly divided into Group A (155 patients) for 2.0g.bid of cefepime,Group B (155 patients) for 2.0g.bid of ceftazidime and Group C (150 patient) for 2.0g. bid of cefathiamidine ( intramuscular injection:once every 12 hours ) , and the periods of treatment were all 7 to 10 days.Control observation and study was carried out following Guiding Principle of Clinical Application of Antibacterial Agents.Results The clinical efficacies in Groups A ,B and C were 94.84%,82.58% and 67.33%respectively(χ2 =11.63,37.96,all P<0.05);the bacterial clearance rates were 92.52%,81.38% and 64.71%respectively(χ2 =8.00,9.97,all P<0.05).The clinical efficacy of Group A >that of Group B>that of Group C;the adverse effectives were 9.68%,10.32% and 9.33% respectively (χ2 =0.09,P>0.05).Conclusion Cefepime may still be used as the first line drugs ,and drug resistance of various degrees has occurred to ceftazidime and cefathi -amidine,and especially cefathiamidine ,which should be used with caution .
10.Comparative studies on mental health status and personality between in-tunnel and out-tunnel operation soldiers
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
Objective To investigate the mental health and personality of soldiers operated inside and outside tunnels,and explore the necessity and particularity of mental training.Method One hundred and four soldiers worked inside tunnel and 88 outside tunnel were tested by Symptom Checklist 90(SCL-90) and Eysenck personality questionnaire(EPQ),and the results were analyzed statistically.Result With an exception of phobia,the SCL-90 scores of most factors were significantly higher in the soldiers worked inside tunnel than outside tunnel(P0.05) on EPQ-E and EPQ-P scores.Some of SCL-90 index scores showed positive correlation with EPQ-P and N dimension scores,and negative correlation with EPQ-E dimension score(P0.05).Conclusion Personality feature is an important factor that influences the mental health of soldiers worked inside tunnel.It is important to adopt appropriate mental training and improve the adaptability of soldiers to the military environment.