3.Investigation on relation between recurrent spontaneous abortion and antiphospholipid thrombosis syndrome
Acta Universitatis Medicinalis Anhui 2001;(2):137-138
Objective To investigate the causes of recurrent spontaneous abortion(RSA) and to know the relation between RSA and antiphospholipid thrombosis syndrome(APL-T). Methods ELISA and PTT-LA were used to detect anticardiolipin antibody(ACA) and lupus anticoagulant(LA) in 32 patients with RSA and 20 normal controls(NC). Results There were 17 positive of antiphospholipid antibody(APA) in RSA group. The incidence was significantly higher than that in NC group. The incidence of LA was also significantly higher than that in NC group. 8 patients were diagnosed as APL-T. Conclusion LA may be the more important reason of RSA. It should be considered as APL-T when RSA is unexplained.
4.Clinical value of 64 slice spiral CT low dose chest scan in diagnosis of pulmonary tuberculosis
Chinese Journal of Primary Medicine and Pharmacy 2017;24(12):1798-1801
Objective To investigate the clinical value of 64 slice spiral CT low dose chest scan in the diagnosis of pulmonary tuberculosis.Methods From January 2015 to January 2016,45 patients with suspected pulmonary tuberculosis were studied.All patients underwent routine chest CT scan and low dose chest CT scan.To compare the difference of radiation dose related parameters between normal dose chest CT scanning and low dose chest CT scan.To observe the display of the characteristics of lung disease by routine dose chest CT scanning and low dose chest CT scan.Results In 45 patients,there were a total of 30 patients were diagnosed with tuberculosis.The diagnostic sensitivity,specificity and diagnostic coincidence rate of conventional CT scan and spiral CT low-dose scan were 93.3% and 86.7% respectively.In low dose CT scanning radiation dose related parameters,the effective dose [(1.36±0.22)mSv vs.(5.24±0.68) mSv],CT dose index[(31.8±3.7) vs.(51.2±6.3)] and dose length product[(35.4±5.4)mGycm vs.(137.9±26.1) mGycm]were significantly lower than those of the conventional dose CT scan,the differences were statistically significant (all P<0.05).Conventional dose and low dose CT scan could show the lung lesions of pulmonary tuberculosis.Comparison between the two groups,low dose CT scanning on the burr sign and grinding glass shadow display rate was low.Compared with the conventional dose CT scanning,the difference was statistically significant (P<0.05).Conclusion In the diagnosis of pulmonary tuberculosis,the radiation dose of 64 slice spiral CT is significantly decreased,be able to clear most of the lung lesions.However,the effect is poor in the display of the grinding glass and the thin and short burr.
5.Relevance theories about tumor stem cells and occurrence and metastasis of tumors:recent progress
Military Medical Sciences 2014;(12):994-996,999
Tumor stem cells (TSCs) are a group of cells which have self-renewal and differentiation potential in tumor tissues.TSCs not only play an important role in the occurrence and development in tumors , but also are closely related to tumors′invasion,metastasis,heterogeneity and chemo-resistance.Further research of TSCs has become a hot spot .This review intends to explain the formation of TSCs ,the relationship between TSCs and the microenvironment , as well as the model of the TSC microenvironment .Signalling pathways and regulatory factors of TSCs are also discussed .
6.Correlation of urine albumin and creatinine ratio and short -term prognosis in patients with acute ischemic stroke
Chinese Journal of Primary Medicine and Pharmacy 2016;23(3):333-336,337
Objective To explore the correlation of urine albumin and creatinine ratio(UACR)and short -term prognosis in patients with acute ischemic stroke (AIS).Methods 112 patients with AIS were selected as the research subjects.The admission UACR and related laboratory examination indexes were detected,the US national institutes of health stroke scale (NIHSS)scores,and 28 d after admission of the modified Rankin scale (mRS) prognostic score were recorded.The NIHSS 5 or more points and NIHSS <5 points,different levels and UACR patient observation index between the different prognosis group were compared.Results NIHSS 5 or more group of patients on admission UACR level[(15.41 ±3.21 mg/g)]was higher than the NIHSS <5 patients (9.52 ±2.04)mg/g (t =12.214,P <0.001);UACR acuity 11.60mg/g group in NIHSS of 5 or more proportion of patients (87.5%),mRS score >2 points (82.1%),the proportion of the recent death patients (23.2%)than the proportion of UACR <11.60mg/g,the proportion of the group (32.1%,25.0%,7.1%;the chi -square values 33.509,34.476,5.598,all P <0.050);MRS score >2 groups of patients UACR level[(16.10 ±3.29)mg/g]was higher than that in patients with mRS score 2 points or less (8.38 ±1.95)mg/g(t =20.132,P <0.001);Pearson correlation analysis showed that the standard of UACR and NIHSS score (r =0.412,P <0.05 ),high -sensitivity C -reactive protein (hs -CRP)(r =0.473,P <0.050),white blood cell count (WBC)(r =0.442,P <0.050),fasting plasma glucose (FPG)(r =0.375,P <0.050)were positively correlated.Multiariable Logistic regression analysis showed that UACR (OR =1.587,P <0.050)was a recent independent risk factors of poor prognosis in patients with AIS. Conclusion UACR the illness severity and recent prognosis of patients with AIS is closely related to high levels of UACR may be recent independent risk factors of poor prognosis in patients with AIS.
7.Clinical effect and safety of different concentrations of atropine preparations in the treatment of ametropia
Chinese Journal of Biochemical Pharmaceutics 2016;36(11):106-108,111
Objective To investigate the effect and safety of Atropine preparations of 0.1%and 0.01%concentrations in the treatment of Ametropia.Methods 123 cases of ametropia from April 2014 to August 2015 in ophthalmic hospital of ningbo were randomly selected and divided into three groups, 41 cases in each group.High concentration group received 0.1%atropine sulfate eye drops treatment,low concentration group received 0.01%atropine sulfate eye drops treatment,and the control group received artificial tear mytear,and three groups were treated for one year.Changes in vision, refraction, intraocular pressure and axial length of the eye were compared after the treatment.Results High concentration group >low concentration group >control group in the the difference of distant visual acuity before and after the treatment ( P<0.05 ) , control group >low concentration group>high concentration group in the refractive index,intraocular pressure and ocular axis length difference before and after treatment (P<0.05),and the effective rate in the low concentration group 85.37%and high concentration group 90.24%had no significant difference.Adverse effects rate in high concentration group was 21.95%which was higher than low concentration group 4.88%(P<0.05).Conclusion 0.1%and 0.01%concentrations of atropine were effective control of Ametropia in flexion and axial length spectrophotometry, and then improve the visual acuity, and the former is better,but the 0.01%concentrations had higher safety.
8.Needle-knife precut versus Plough-knife precut in difficult biliary cannulation
China Journal of Endoscopy 2016;22(2):50-52
Objective To discuss which is more efficient between Needle-knife precut and Plough-knife precut in difficult biliary cannulation. Methods The difference in the average time of cannula, percentage of cannula achieve-ment and the complication rate between the two kinds of operation were compared. Results The percentage of can-nula achievement about the Needle-knife precut is higher than Plough-knife precut, while there is no notable differ-ence in average time of cannula and the complication rate between the two precuts. Conclusion Needle-knife precut is more efficient than Plough-knife precut in difficult biliary cannulation, if guide wire can not get into pancreatic duct.
9.Abstract Writing Skills of Medical English Research Papers
Chinese Journal of Medical Education Research 2006;0(11):-
Academic English abstract is an important means of achieving international academic exchange.This article introduces writing content and writing skills for medical academic English abstract.
10.Characteristics and management of 301 cases of civilian firearm injuries in maxillofacial region
Journal of Practical Stomatology 2001;17(3):220-222
Objective: To view the characteristics and the primary treatment of civilian firearm wound in the maxillofacial region.Methods: 301 cases of the casualties admitted to our hospital were retrospectively investigated,the epidemic, etiology, wound characteristics, and treatments of the patients were viewed respectively. Results: Of all the cases, the ratio of male to female was 5.1∶1.0. 57% of the injuries were caused by gunshot, 66% were with multiple injuries.16% combination wound were craniocerebral injuries. In this group of patients, more than 900 wound tracks were found, 72% of the tracks were nonpenetrating and 67% of those were with foreign bodies lodged in. Burns with blast injuries were the main complex wounds, which mostly occurred in explosion. The treatments mainly included life maintaining, earlier debridement and infection control. Conclusions: The maxillofacial firearm injuries are complex and have their own characteristics depending on the firearms, the wound styles and the regional anatomy. All the factors must be considered when treatment is given.