Objective: To investigate the clinical avalue of real time threshold manual triggering technique in the lower extremity arterial CT angiography .Methods :A total of 70 patients with clinically suspected lower extremity arterial disease underwent lower extremity arterial CT examination ,and the patients were randomly divided into two groups .In the first group 35 patients ,the automatic threshold triggering technique was used .After the threshold reached to 150 Hu ,6 s was delayed before scanning .The other group of 35 patients with manual triggering was used to observe the time density curve .When the peak value was stable ,scanning was started at once .The delay time of the two groups was analyzed and the image quality of the two groups was evaluated .The image quality evaluation included the branch level ,the smooth degree of the arterial edge , the interference of the vein and the CT value of the arterial segment .Results:There were significant differences in the starting delay time of the two trigger modes (P=0 .002 ,P<0 .05) ,and the auto trigger group was earlier than the manual triggering group .Between the two trigger modes ,there was no significant difference in the distal branches and vessel edge of abdominal‐iliac artery and femoral popliteal artery display ability .In the lower limb artery ,the image quality of manual triggering group was higher than that of the automatic trigger group ,the two groups had statistical significance (P=0 .004 , P=0 .003) .The same as to the distal branch and the edge of the vessel of the foot (P=0 .003 ,P=0 .003) .Two sets of images in the lower limb vein interference score had no significant difference ( P> 0 .05 ) .CT value had no significant difference in abdominal‐iliac artery ,femoral‐calf and popliteal arteries between the two groups ,while that in the dorsalis pedis artery had statistical significance between the two groups (P=0 .006) .Four levels of CT values in manual triggering group were higher than those in the automatic trigger group .Conclusions :Real time threshold manual triggering technique takes into account the individual differences of patients ,so the patient's delay scan time can be evaluated better and higher quality of lower extremity arterial images can be acquired .

Objectives:To investigate the clinical efficacy and outcome of lateral lumbar interbody fusion in the treatment of lumbar spinal stenosis(LSS)with redundant nerve roots(RNRs).Methods:The data of 48 LSS patients with RNRs(23 males and 25 females,aged 45-81 years,on average 65.4±7.5 years)treated with lat-eral lumbar interbody fusion between January 2018 and July 2022 in our hospital were analyzed retrospec-tively.Among the patients,17 cases received single-level surgery and 31 cases received multi-level surgery.On the basis of the postoperative supine MRI scans,the patients were divided into RNRs relieved group(group A)and RNRs unrelieved group(group B).Radiographic assessments included disc heights,segmental angle and cross-sectional area of the spinal canal at the RNRs segment before and after operation were per-formed.The visual analogue scale(VAS),Oswestry disability index(ODI)and Japanese Orthopaedic Association(JOA)score were used to evaluate the clinical outcomes at preoperation and 1 month after surgery.Results:All patients underwent surgery successfully.The preoperative cross-sectional area of the spinal canal was 65.2±21.5mm2 in group A and 35.9±11.5mm2 in group B,with a significant difference(P＜0.05).The posterior disk height and cross-sectional area of the spinal canal was 8.3±1.7mm and 92.6±25.8mm2 respectively in group A,and that of group B was 6.0±2.3mm and 45.4±12.1mm2 respectively,the differences were significant-ly statistical(P＜0.05).Furthermore,in 1 month after operation the VAS leg pain,ODI and JOA scores was 2.4±0.8,(24.1±3.0)%and 22.8±1.9 respectively in group A,and that of group B was 3.3±0.8,(30.2±4.4)%and 17.7±2.5 respectively,the differences were significantly statistical(P＜0.05).The total incidence of complications was 10.4%,including anterolateral thigh pain in 4 cases and hip flexor weakness in 1 case,which were released at 3 months of follow-up.Conclusions:Lateral lumbar interbody fusion can eliminate RNRs by restoring postoperative posterior disc height and enlarging the cross-sectional area of spinal canal,which provides an effective treatment for most LSS patients with RNRs.

Objective To investigate the effects of different dose of diammonium glycyrrhizinate ( DG ) on alopecia mice hair growth . Methods Alopecia mouse model was established by using cyclophos-phamide .The 50 , 100 mg · kg -1 · d-1 DG and 100 mg · kg -1 · d -1 saline were fed separately in low-dose DG group , high-dose DG group and blank group , for 8 weeks after alopecia.Pathological changes of the hair follicle in alopecia area were observed by using HE staining and electron microscopy.Results Compared with the model group and the blank group , at each time point , it was remarkable difference in statistics of the number of hair follicle in high -dose DG group ( P <0.05 ) . Electron microscopy confirmed the degree of mitochondrion vague and vacuolar in remaining hair follicle cell in high -dose DG group were lighter than model group and the blank group after 8 weeks. Conclusion High-dose DG promotes hair growth by reducing the hair follicle cell damage.