1.A Literature Review on Asthma and Chronic Obstructive Pulmonary Disease Among Domestic and Overseas Farmers
Siyoung KIM ; Seongyong YOON ; Jinseok KIM ; Seong-yong CHO ; Hyun Woo PARK ; Daehwan KIM ; Gayoung KIM ; Jisoo KANG ; Kyungsu KIM ; Dongphil CHOI ; Seok-Ju YOO
Journal of Agricultural Medicine & Community Health 2023;48(4):251-261
Objective:
Farmers are known to have high prevalence of asthma and chronic obstructive pulmonary disease(COPD). This study aims to investigate the current status of asthma and COPD in domestic and foreign farmers with the ultimate goal of raising awareness of asthma and COPD among farmers and contribute to supporting evidence for the prevention of respiratory diseases in farmers.
Methods:
The study utilized data from the "Farmer’s Occupational Disease Survey," conducted by the Rural Development Administration, to determine the prevalence of respiratory diseases in domestic farmers.The prevalence of asthma and COPD in overseas farmers was evaluated by researching other foreign studies and articles.
Results:
The prevalence of asthma and COPD in domestic farmers was less than of foreign farmers’.The prevalence of asthma in domestic farmers was high as upto 8.4% and COPD upto 5.5%. Studies from Europe and America showed prevalence of asthma in farmers high as upto 14.8% and COPD upto 17.1%.
Conclusions
This study conducted an investigation using the 'Survey on Occupational Diseases and Injuries in Farmers to understand the current status of asthma and COPD in domestic farmers. Due to a lack of relevant domestic research, we examined and compared with the research results on asthma and COPD among overseas farmers. Further research is necessary and preventive measures for respiratory diseases need to be developed.
2.Demand for Priorities for Preventing Occupational Diseases among Farmers
Ae-Rim SEO ; Ji-Youn KIM ; Bokyoung KIM ; Gyeong-Ye LEE ; Kyungsu KIM ; Ki-Soo PARK
Journal of Agricultural Medicine & Community Health 2023;48(4):239-250
Objective:
This study was a preliminary study for the prevention programs for farmers' occupational diseases. It selected the priorities recognized by farmers, such as occupational diseases, and also identifies the effectiveness and feasibility of prevention programs among diseases recognized by farmers. Therefore, we plan to use it as basis data for future farmer safety and health programs.Method: The subjects of the study were farmers living in the region, selected through a snowball recruitment method, and a total of 671 people were targeted. The priority selection method was the Basic Priority Rating System (BPRS) method, and among the occupational diseases, programs to prevent musculoskeletal diseases, cardiovascular and respiratory diseases, and pesticide poisoning were surveyed on the effectiveness and feasibility of farmers.
Results:
Among occupational diseases, the highest priority was musculo-skeletal disease, followed by respiratory disease and pesticide poisoning. Among the programs for musculoskeletal disease, 'use of agricultural work convenience equipment and auxiliary tools' had the highest perceived effectiveness and feasibility. Among the five programs for pesticide poisoning, ‘equipment of protective equipment such as pesticide protective clothing/glove’ had the highest effectiveness at 67.4%, and ‘compliance with pesticide use instructions’ had the highest level of feasibility at 64.3%. Among the four programs to prevent respiratory diseases, ‘wearing a dust mask or gas mask’ was the highest at 65.5% in terms of both effectiveness and feasibility.
Conclusion
When carrying out safety and health programs for farmers, the priorities recognized by farmers should be taken into consideration, and the program contents should also be developed taking into account the size of effect and feasibility recognized by farmers.
3.Health-related Quality of Life Outcomes of Adalimumab for Patients With Rheumatoid Arthritis in Korea
Myeung-su LEE ; Chang Hoon LEE ; Hye Soon LEE ; Yoon-Kyoung SUNG ; Jung Ran CHOI ; Kyungsu PARK ; Mi-Kyoung LIM ; Byoong Yong CHOI ; Hyoun-Ah KIM ; Seung Won CHOI ; Yusun LEE ; Wan-Hee YOO
Journal of Rheumatic Diseases 2021;28(2):68-75
Objective:
Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disorder that impairs patients’ overall health-related quality of life (HRQOL). In this study, we evaluated the effect of adalimumab in Korean patients with active RA on HRQOL.
Methods:
Patients included in the study had moderate to severe active RA that did not respond to conventional drugs with a Disease Activity Score of 28 joints >3.2 and were biologics-naïve. All patients received adalimumab 40 mg subcutaneously every other week and were followed for 24 weeks. The primary endpoint was the change in baseline Health Assessment Questionnaire Disability Index (HAQ-DI) score at week 24. Secondary endpoints were changes in the EuroQol 5-dimension 3-Level (EQ-5D-3L) baseline score and Short Form 36-Item Health Survey (SF-36) domain scores at weeks 12 and 24 and change in baseline HAQ-DI score at week 12.
Results:
In total, 91 Korean patients were included. Ninety-three percent of patients were in high disease activity with a baseline mean DAS28 value of 6.1 within all patients. The mean change from baseline in HAQ-DI scores were −0.46 at week 12 and∼0.67 at week 24 (p<0.0001). Additionally, EQ-5D-3L score at weeks 12 and 24 had significantly improved (p<0.0001) compared to baseline. SF-36 at weeks 12 and 24 had significantly improved (p<0.0001, p=0.0001) compared to baseline.
Conclusion
Treatment with adalimumab resulted in significant improvement in HAQ-DI, EQ-5D-3L, and SF-36 scores at 12 and 24 weeks in Korean RA patient.