1.Prediction Model of Quality of Life in Elderly Based on ICF Model.
Heeyoung SO ; Hyunli KIM ; Kyungok JU
Journal of Korean Academy of Nursing 2011;41(4):481-490
PURPOSE: The purpose of this study was to identify from the International Classification of Functioning model, factors influencing quality of life in elderly persons and to describe the concrete pathway of influence and the power of each variable. METHODS: The sample included 334 elders who lived in 5 districts of D Metropolitan City. A structured questionnaire was used and the collected data were analyzed for fitness, using the AMOS 18.0 program. RESULTS: This model was concise and extensive in predicting the quality of life of elders. The research verified the factors influencing quality of life for elders as direct factors such as activity of daily living (ADL) (beta=.13, t=2.47), leisure activity (beta=.55, t=5.04), social disengagement (beta=-.25, t=-2.25), and depression (beta=-.62, t=-10.86). Indirect factors including economic status (gamma=.17, p=.009), type of residence (gamma=.19, p=.004), ADL (gamma=.12, p=.027) were important factors in predicting quality of life for elders. These variables explained 75.6% of variance in the prediction model. CONCLUSION: The findings indicate a need for the nursing scientific community to develop intervention programs considering these variables to improve the quality of life for elders.
Activities of Daily Living
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Aged
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Aged, 80 and over
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Depression
;
Female
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Humans
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Leisure Activities
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Male
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*Models, Psychological
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*Quality of Life
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Questionnaires
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Socioeconomic Factors
2.Field evaluation of the safety and immunogenicity of a classical swine fever virus E2 subunit vaccine in breeding and nursery animals on Jeju Island, South Korea
Guehwan JANG ; Eun-Joo KIM ; Seong-Cheol CHO ; Sung-Up MOON ; Byeong Soo KIM ; Jinhee KIM ; Kyoung Ju JEONG ; Kyungok SONG ; Seong Hwan MUN ; Won-Myoung KANG ; Jonghoo LEE ; Changnam PARK ; Hyoung-Seok YANG ; Changhee LEE
Clinical and Experimental Vaccine Research 2022;11(3):264-273
Purpose:
Classical swine fever (CSF) reemerged on CSF-free Jeju Island where vaccination is not practiced by the unintentional injection of a live attenuated vaccine (modified live attenuated vaccines–low-virulence Miyagi [MLV-LOM]) in 2014. Since the Jeju provincial authority is considering adopting a voluntary immunization policy using a CSF-E2 subunit vaccine to combat LOM-derived CSF endemic, this study aimed to evaluate in Jeju herds.
Materials and Methods:
Two vaccination trials using the Bayovac CSF-E2 vaccine licensed for use in South Korea assessed the safety and humoral immunity of the CSF-E2 vaccine in breeding (trial 1) and nursery animals (trial 2) under farm application conditions.
Results:
Neither local nor systemic (including reproductive) adverse effects were objectively observed in pregnant sows and young piglets following a respective vaccination regime at pregnancy or weaning, respectively. Trial 1 showed that sows immunized with the CSF-E2 vaccine possessed high and consistent E2-specific and neutralizing antibody levels. The CSF-E2 vaccine-immunized pregnant sows subsequently conferred appropriate and steady passive immunity to their offspring. In trial 2, a double immunization scheme of the CSF-E2 vaccine in piglets at 40 and 60 days of age could elicit a consistent and long-lasting adequate antibody response. Additionally, the two trials detected no E rns -specific antibody responses, indicating that CSF-E2 vaccine can differentiate infected from vaccinated animals (DIVA).
Conclusion
Our trial data collectively provide invaluable information on applying the CSFE2 subunit vaccine to circumvent the possible drawbacks associated with the MLV-LOM concerning the safety, efficacy, and DIVA, in the LOM-endemic field farms and contribute to advanced CSF eradication on Jeju Island.