1.Diffuse Neonatal Hemangiomatosis Successfully Treated with High Dose Corticosteroid.
Yong Won SEO ; Sung Yul LEE ; Jong Suk LEE ; Kyu Uang WHANG ; Hye Kyung LEE
Annals of Dermatology 1998;10(2):112-115
Diffuse neonatal hemangiomatosis is a fatal disorder characterired by multiple cutaneous and visceral hemangiomas. The organs most commonly affected are the gastrointestinal tract, brain, liver and lung. The complications are high output cardiac failure, gastrointestinal bleeding and hydrocephalus. We present a patient with diHuse neonatal hemangiomatosis associated with massive hepatic involvement and high output cardiac failure, which was successfully treated with high dose corticosteroid.
Brain
;
Gastrointestinal Tract
;
Heart Failure
;
Hemangioma
;
Hemorrhage
;
Humans
;
Hydrocephalus
;
Liver
;
Lung
2.The Results of Phacoemulsification Cataract Surgery in Patients with Behcet's Disease.
Young Wook KIM ; Kyung Yul SEO
Journal of the Korean Ophthalmological Society 2006;47(12):1943-1947
PURPOSE: To evaluate the outcomes and complications of cataract surgery, using phacoemulsification in patients with Behcet's disease. METHODS: Twenty eyes of fourteen patients with Behcet's disease, who underwent extracapsular cataract extraction using phacoemulsification and intraocular lens implantation between July 2001 and March 2004, were included in this study. Their postoperative visual acuity and complications were reviewed. RESULTS: Ocular attacks after cataract surgery occurred in 10 eyes (50%). Uveitis developed in 10 of 12 eyes (83.3%) that had a uveitis-free interval of less than six months. On the other hand, in eight eyes that lasted more than 12 months with no uveitis, no postoperative ocular attack was found (p<0.01, Chi-square test). The incidence and severity of uveitis did not appear to increase upon surgery. Visual acuity improved in 17 eyes (85%). However, after 1 year postoperatively, a statistically significant decrease in visual acuity was observed in the recurrent uveitis group (p=0.05, t-test). CONCLUSIONS: Cataract surgery, using phacoemulsification and intraocular lens implantation, is tolerable in patients with Behcet's disease. The most predictive factor of ocular attacks and prognosis after cataract surgery was the 'uveitis free' duration before surgery. A uveitis-free interval of more than 12 months in duration was predictive of the best prognosis.
Behcet Syndrome
;
Cataract Extraction
;
Cataract*
;
Hand
;
Humans
;
Incidence
;
Lens Implantation, Intraocular
;
Phacoemulsification*
;
Prognosis
;
Uveitis
;
Visual Acuity
3.Comparison of Long Term Prognosis between Carotid Endarterectomy versus Stenting; A Korean Population-Based Study Using National Insurance Data
Kwon Duk SEO ; Kyung Yul LEE ; Sang Hyun SUH
Neurointervention 2019;14(2):82-90
PURPOSE: Although carotid endarterectomy (CEA) is recommended as a treatment for carotid stenosis rather than carotid artery stenting (CAS), CAS has been preferred in Korea. The aim of this study was to analyze long-term outcomes after CAS compared with CEA using Korean nationwide insurance data. MATERIALS AND METHODS: We obtained all data from the nationwide database of the Health Insurance Review & Assessment Service (HIRA) during the study period using several codes regarding the procedure or operation. We included the HIRA data, which included at least one-year follow-up after the procedures. The outcomes associated with both procedures were death, recurrence of ischemic stroke, and admission for cerebral hemorrhage. RESULTS: A total of 16,065 eligible patients who were treated with CAS or CEA between 1 January 2007 and 31 December 2016 were analyzed. The number of patients with CAS and CEA was 12,173 (75.8%) and 3,892 (24.2%), respectively. 8,976 patients (55.9%) were classified as symptomatic patients. CAS was associated with a higher risk of all-cause mortality (adjusted hazard ratio [HR], 1.282; 95% confidence interval [CI], 1.173–1.400). The adjusted rates for recurrent ischemic stroke and cerebral hemorrhage between CAS versus CEA were 24.9% versus 15.9% (HR, 1.474; 95% CI, 1.325–1.639) and 1.5% versus 0.9% (HR, 2.026; 95% CI, 1.322–3.106), respectively. In young symptomatic patients, there was no statistically significant difference in all-cause mortality and cardiovascular death between CAS and CEA. CONCLUSION: Our study using Korean nationwide insurance data demonstrated similar results to previous studies. Until further evidence of CAS is established through prospective studies, CAS should be performed in selected patients according to current guidelines.
Carotid Arteries
;
Carotid Stenosis
;
Cerebral Hemorrhage
;
Endarterectomy
;
Endarterectomy, Carotid
;
Follow-Up Studies
;
Humans
;
Insurance
;
Insurance, Health
;
Korea
;
Mortality
;
Prognosis
;
Prospective Studies
;
Recurrence
;
Stents
;
Stroke
4.Hyperintense Vessels on FLAIR MRI in Patients With Acute Middle Cerebral Artery Infarction Revealed Pial Collateral on Cerebral Angiography.
Tae Jin SONG ; Kyung Im SEO ; Sang Hyun SUH ; Kyung Yul LEE
Journal of the Korean Neurological Association 2010;28(2):98-100
Hyperintense vessels are frequently observed on fluid-attenuated inversion recovery imaging in acute ischemic stroke patients. Some investigators suggest that a hyperintense vessel sign in patients with middle cerebral arterial occlusion results from collateral blood flow originating in neighboring arterial territories, especially via pial collaterals. We report two cases of acute proximal middle cerebral arterial infarction that exhibited hyperintense vessels signs on fluid-attenuated inversion recovery imaging accompanying pial collaterals as confirmed by cerebral angiography.
Cerebral Angiography
;
Cerebral Infarction
;
Collateral Circulation
;
Glycosaminoglycans
;
Humans
;
Infarction
;
Infarction, Middle Cerebral Artery
;
Middle Cerebral Artery
;
Research Personnel
;
Stroke
5.Sleep-Related Erections(SREs) in Chronic Vegetative State Patients.
Chang Duck SEO ; Kyung Tae KO ; Sung Yul PARK ; Sang Wook LEE ; Won Ki LEE ; Sung Yong KIM ; Hayoung KIM ; Dae Yul YANG
Korean Journal of Andrology 2006;24(1):23-28
PURPOSE: To determine whether sleep-related erections(SREs) occur during chronic vegetative state and if so, to investigate what factors are involved. MATERIALS AND METHODS: Twenty-six men in a vegetative state aged 16~65 were selected. Exclusion criteria were the lack of informed consent, mean blood pressure under 90/60 mmHg during last 3 days, erectile dysfunction before brain injury, and a history of any anti-androgen treatment. Serum testosterone, albumin, sex hormone binding globulin(SHBG), and dehydroepiandrosterone sulfate(DHEAS) were assayed, and bioavailable testosterone(cBT) and free testosterone(cFT) were calculated. Nocturnal penile erections were counted and evaluated using the Rigiscan device for72 hours. Data on the number of erections, erection duration, minimal and maximal base tumescence, minimal and maximal tip tumescence, and base and tip rigidity were taken. RESULTS: SREs were noted in 25 patients. The mean erection number was 4.65+/-3.93(1~15), and the mean erection duration was 128.85+/-46.86 minutes(0~478.5). SREs were negatively correlated with age(r=-0.445, p<0.05), systolic BP(r=-0.394, p<0.05) and diastolic BP(r=-0.403, p<0.05), but positively correlated with DHEAS(r=0.395, p<0.05). SREs were not correlated with total testosterone, cBT or cFT. CONCLUSIONS: These preliminary findings suggest that SREs are a normal occurrence in vegetative patients. They contribute to penile blood perfusion if the supraspinal erection control center is intact and serum testosterone level is above the minimum required for SREs.
Blood Pressure
;
Brain Injuries
;
Dehydroepiandrosterone
;
Dehydroepiandrosterone Sulfate
;
Erectile Dysfunction
;
Humans
;
Informed Consent
;
Male
;
Perfusion
;
Persistent Vegetative State*
;
Testosterone
6.Serial Changes of Fluid-Attenuated Inversion Recovery Hyperintense Vessels in a Patient With Middle Cerebral Artery Stenosis.
Yeo Jin OH ; Kwon Duk SEO ; Sang Hyun SUH ; Kyung Yul LEE
Journal of the Korean Neurological Association 2014;32(1):47-49
No abstract available.
Cerebral Infarction
;
Constriction, Pathologic*
;
Humans
;
Magnetic Resonance Imaging
;
Middle Cerebral Artery*
7.Changes in Corneal Keratometry Readings after Corneal Collagen Cross-Linking Using Alcohol in Keratoconus Patients.
Si Jin NOH ; Ji Min AHN ; Kyung Eun HAN ; Kyoung Yul SEO
Journal of the Korean Ophthalmological Society 2012;53(11):1591-1596
PURPOSE: To evaluate the changes in corneal keratometry (K) readings after corneal collagen cross- linking (CXL) using 20% alcohol in primary keratoconus and keratectasia after refractive surgery. METHODS: Twelve eyes of 10 patients with primary keratoconus and 3 eyes of 3 patients with keratectasia after refractive surgery were included in the present study. Best-corrected visual acuity (BCVA) and mean K, corneal astigmatism by corneal topography, and mean K, corneal astigmatism, and spherical equivalent (SE) by auto refractometer were evaluated at baseline, and 6 months postoperatively. Eight eyes of 7 patients were also evaluated 1 year postoperatively. RESULTS: Mean BCVA improved from log MAR 0.66 +/- 0.50 to log MAR 0.55 +/- 0.58 (p = 0.100) at 6 month after CXL. In corneal topography, mean K significantly decreased from 50.04 +/- 5.88 D to 49.18 +/- 6.15 D (p = 0.019), and corneal astigmatism slightly decreased from 5.33 +/- 4.47 D to 5.29 +/- 4.88 D (p = 0.755) at 6 months after CXL. According to the auto refractometer, mean K significantly decreased from 48.53 +/- 5.94 D to 47.95 +/- 5.79 D (p = 0.038), corneal astigmatism significantly decreased from 3.95 +/- 2.54 D to 3.52 +/- 2.40 D (p = 0.010), and SE significantly decreased from -6.25 +/- 3.45 D to -5.40 +/- 2.91 D (p = 0.037) at 6 months after CXL. Significant mean K and corneal astigmatism decreases in topography were also observed at 1 year after CXL. Complications related to CXL were not observed. CONCLUSIONS: CXL using 20% alcohol appears to be a safe and promising treatment modality with less corneal stromal damage in progressive primary keratoconus and keratectasia after refractive surgery.
Astigmatism
;
Collagen
;
Corneal Topography
;
Eye
;
Humans
;
Keratoconus
;
Reading
;
Refractive Surgical Procedures
;
Visual Acuity
8.A Case of Postpartum Cerebral Angiopathy.
Seo Hyun KIM ; Kyung Yul LEE ; Il Nam SUNWOO ; Hyun Sook KIM ; Jin Il JUNG ; Dong Ik KIM
Journal of the Korean Neurological Association 2000;18(3):353-355
Postpartum cerebral angiopathy is a benign, reversible clinicoradiologic syndrome. The clinical significance of this syndrome is the difficulty in differentiating it from other severe disorders such as subarachnoid hemorrhage and cere-bral vasculitis. A 25-year-old woman who developed a severe headache, transient total blindness ,and generalized tonic clonic seizures 14 days postpartum was admitted to our hospital. A MRI of the brain revealed a bilateral anterior cere-bral artery (ACA) infarction. A cerebral angiography showed the narrowing of the M1 and M2 segments of the left middle cerebral artery (MCA), the right MCA M1 segment, and the A1 and proximal A2 segments of the right ACA. Also, it showed the narrowing of the proximal basilar artery portion from which the anterior inferior cerebellar artey arose, P1, P2, and P3 segments of the left posterior cerebral artery (PCA), and the right PCA P1 segment. With the treatment of nimodipine, the abnormalities on these studies were markedly improved two weeks later.
Adult
;
Arteries
;
Basilar Artery
;
Blindness
;
Brain
;
Cerebral Angiography
;
Cerebrovascular Disorders
;
Female
;
Headache
;
Humans
;
Infarction
;
Magnetic Resonance Imaging
;
Middle Cerebral Artery
;
Nimodipine
;
Passive Cutaneous Anaphylaxis
;
Posterior Cerebral Artery
;
Postpartum Period*
;
Pregnancy Complications
;
Seizures
;
Subarachnoid Hemorrhage
;
Vasculitis
9.Rescue Use of Tirofiban for Acute Carotid In-Stent Thrombosis.
Kwon Duk SEO ; Kee Oog LEE ; Dong Joon KIM ; Kyung Yul LEE
Yonsei Medical Journal 2008;49(1):163-166
Carotid artery stenting is widely performed for extracranial carotid artery stenosis. In-stent thrombosis is a rare but potentially devastating complication. We present a case of acute in-stent thrombosis immediately following stent insertion and post-balloon dilatation in a 64-year-old male. Thrombosis was successfully treated by intravenous tirofiban, a glycoprotein IIb/IIIa receptor inhibitor.
Acute-Phase Reaction/*drug therapy/*pathology
;
Angiography
;
Carotid Artery Diseases/*drug therapy/*pathology
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Stents
;
Thrombosis/*drug therapy/*pathology
;
Tyrosine/*analogs & derivatives/therapeutic use
10.The Short-Term Effect of Topical Cyclosporine A 0.05% in Various Ocular Surface Disorder.
Yeo Jue BYUN ; Tae Im KIM ; Kyung Yul SEO
Journal of the Korean Ophthalmological Society 2008;49(3):401-408
PURPOSE: To evaluate the efficacy of topical cyclosporine A 0.05% (Restasis) in the treatment of dry eye symptoms caused by various ocular surface inflammatory disorders. METHODS: Thirty three patients with ocular surface diseases, including 17 with Sjogren syndrome, 8 with meibomian gland dysfunction (MGD), 4 with Thygeson's keratitis, and 4 with atopic keratoconjunctivitis (AKC) were treated with Restasis twice a day for 3 months. During follow up, the symptom severity assessment (burning, itching, foreign body sensation, blurring, photophobia, and pain), TBUT (tear break up time), Schirmer score, frequencies of artificial tear use, onset of symptomatic relief, subjective satisfaction score, and side effects were evaluated. RESULTS: In patients with Sjogren syndrome, foreign body sensation, blurring, photophobia, and pain were reduced after treatment, and the mean Schirmer score, TBUT increased and frequencies of artificial tear use decreased significantly. In patients with MGD, photophobia was reduced after treatment, TBUT and artificial tear use improved after 2 months, and the Schirmer score increased at 3 months. In patient's with Thygeson's keratitis, foreign body sensation and photophobia reduced, and the Schirmer score was increased at 3 months. No significant changes in symptoms, Schirmer score, or TBUT were observed in patients with AKC. Of all subjects, 55% reported symptomatic relief between 3 and 5 weeks after treatment. The mean satisfaction score after treatment was the highest for patients with Sjogren syndrome. Two subjects reported a temporary burning sensation, and one subject quit using Restasis because of bitter taste and a burning sensation. CONCLUSIONS: Treatment with Restasis appeared to be effective in treating dry eye symptoms in patients with Sjogren syndrome. It was shown to be partially helpful in patients with MGD and Thygeson's keratitis, while it showed no beneficial effect in patients with AKC.
Burns
;
Cyclosporine
;
Eye
;
Follow-Up Studies
;
Foreign Bodies
;
Humans
;
Keratitis
;
Keratoconjunctivitis
;
Meibomian Glands
;
Photophobia
;
Pruritus
;
Sensation
;
Sjogren's Syndrome
;
Tears