Acquired multiple cavernous hemangiomatosis appear on the skin and internaI organs, including in particular the skeleton, the brain and the liver in childhood or in adult life in the 4th and 5th decades. It is extremely rare for cutaneous hemangiomas associated with internal lesions to arise de novo in adults. The lesions persist indefinitely and symptom-free survival to old age is possible, despite the presence of hemangiomatosis in liver, heart or kidney. A 53 year-old male patient had multiple, non-tender, bluish to violet colored. pea to walnut sized, cutaneous, some pedunculated nodules on the entire body for 8 years. Histopathologically, there were non-capsulated vascuiar tumor consisting of large variable sized blood vessels in the dermis and some organizing thrombi. There was no evidence of malinant change.
Child ; Adult ; Male ; Female ; Humans ; Hemangioma

Since the introduction of percutaneous mitral valvotomy(PMV) in 1984, PMV was an effecive alternative to surgical commissurotomy in selected patients with severe mitral stenosis. Also PMV was an excellent palliative strategy in such patients who were high risk for operative management or longterm anticoagulation was not feasible. We performed PMV in a patient with very tight mitral stenosis and severe pulmonary hypertension under the general anesthesia because the patient was anticipated to be uncooperative due to mental problem, who was diagnosed as schizophrenia 16 years ago. Robinol was used for premedication and i.v fentanyl was used for maintenance of anesthesia. Inoue balloon was introduced into the LV and gradual ballooning was performed with favorable results. Total anesthesia time and interval from internal jugular vein puncture to the completion of valvuloplasty were 1 hour 45 min and 40 minutes respectively. Hemodynamic variables were improved immediately after intervention and mitral valve area was increased from 0.5cm2 to 1.3cm2.
Anesthesia ; Anesthesia, General* ; Fentanyl ; Hemodynamics ; Humans ; Hypertension, Pulmonary ; Jugular Veins ; Mitral Valve ; Mitral Valve Stenosis* ; Premedication ; Punctures ; Schizophrenia*

Sjogren's syndrome has been considered to be an autoimmune disease affecting various organs including salivary and lacrimal glands. It occurs most commonly in middle-aged women, and less than 20 cases with primary Sjogren's syndrome have been reported in children. An 11-yim-old boy presented with recurrent annular erythema on the face that had been present for 2 years. A schirmers test showed a positive result. ANA was detected at a dilution of 1:640. Anti-Ro/SSA and anti-La/SSB antibodies were also detected. On histological examination, lymphocytes were infiltrated in the periappendegeal areas as well as the papillary and reticular dernis. The skin findimg is uncommon in children, but has become a characteristic feature of childhood Sjogrens syndrome with anti-Ro and/or anti-La antibodies.
Antibodies ; Autoimmune Diseases ; Child ; Erythema* ; Female ; Humans ; Lacrimal Apparatus ; Lymphocytes ; Male ; Sjogren's Syndrome* ; Skin

Lentigo maligna, a precancerous tumor arising from abnormal melanocytes, is a chronic, slowly progressive, pigmented lesion with a range of colors from pale tan to black and an irregular shape, The commonest location of lentigo maligna is the face during the sixth and seventh decades of life. Less frequently, the lesion occurs on an extrafacial area such as the hand or lower leg. In the late stage, lentigo maligna transforms into invasive malignant melanoma. A 50-year-old male patient had a well-defined, black pigmented patch on the right sole for 30 years. The histopathologic examination revealed numerous vacuolated melanocytes clusters at the dermo-epidermal junction with invasion of the epidermis. There was no evidence of dermal invasion by atypical melanocytes.
Epidermis ; Hand ; Humans ; Hutchinson's Melanotic Freckle* ; Leg ; Lentigo* ; Male ; Melanocytes ; Melanoma ; Middle Aged ; Triacetoneamine-N-Oxyl

No abstract available.
Gastrointestinal Stromal Tumors* ; Hemorrhage*

Recent development of oral and maxillofacial surgery has taken an interest in the regeneration of facial bone defects. For the reconstruction of bony defects, autogenousbone grafts have been widely used. However, there are some clinical problems ; the morbidity of donor sites, resorption of autogenous bone graft and the availability of the proper form and size. The purpose of this study is to find the proper filling materials for the bone defects. The present study was designed to evaluate the roles and regenerating capacity of maikture of freeze-dried domineralized allogenic bone and hydroxylapatite. Fifteen adult New Zealand white rabbits were used as the experimental animal, Four trephine defects were made by drilling on the parietal bone of each rabbit. The size of each defects was 8x8mm. In first group, the defect was filled with freeze-dried demineralized allogenic bone and hydroxylapatite. The defect in second group was filled with autogenous bone chip only. The third group was filled with autogenous bone chip and hydroxylapatite. The fourth group was filled with freeze-dried dimineralized allogenic bone only. The results were carefully examined grossly and micorsocopically from the 2 weeks to 12 weeks postoperatively. The following results were obtained ; 1. In the case of the graft with autogenous bone chip only, new bone formation was more active than any other groups. 2. In the case of the graft with combination of freeze-dried demineralized allogenic bone and hydroxylapatite, new bone formation was similar to the case of autogenous bone and hydroxylapatite mixture. 3. In the case of the graft with freeze-dried demineralized bone, new bone formation was observed, but less than the other groups. And the time of new bone appeared was later than the other groups. A combination of freeze-dried deminearalized allogenic bone and hydroxylapatite plays an effective role in forming new bone. The results of this study may suggest the possible usage of the mixture of freeze-dried allogenic bone and hydroxylapatite as an alternative to autogenous bone in maxillofacial orthopedic surgery.
Adult ; Animals ; Bone Regeneration* ; Durapatite* ; Facial Bones ; Humans ; Orthopedics ; Osteogenesis ; Parietal Bone ; Rabbits ; Regeneration ; Surgery, Oral ; Tissue Donors ; Transplants*

A statistical evaluation was made on 248 patients who were consulted to the Department of Dermatology during the disabled patients admission in Korea Veterans Hospital from July 1, 1980 to June 30, 1982. The resuIts were as followings: l. Among the 248 disabled patients, the most common patients, who constituted 68. 8% of the total, were amputee of lower extremity (25.2%), patient of posttraumatic osteoarthritis (23. 2/) and paraplegia (20. 4%). 2. In age distribution, the most frequent age groups were 50 to 59 years, 42, 4, and the lowest age groups were 60 to 69 years, 4. 0g. 3. The 6 most common dermatoses were Eczema (36. 8%), Fungal infection (33. 6%), Drug eruption (8. 0%), Acne vulgaris (6. 4%), Urticaria and Scabies (3. 2% each). 4. In seasonal distribution, the highest incidence (32. %) occurred on winter, and the lowest incidence (14. 0%) on Spring. Eczema was prevalent during Autumn and Winter season and Fungal infection during Summer season. -countinue-
Acne Vulgaris ; Age Distribution ; Amputees ; Dermatology* ; Drug Eruptions ; Eczema ; Hospitals, Veterans ; Humans ; Incidence ; Korea ; Lower Extremity ; Osteoarthritis ; Paraplegia ; Scabies ; Seasons ; Skin Diseases ; Urticaria

Vitiligo is a relatively common depigmentary disorder occurring in approximately 1-2% of the general population. All races are affected. Both sexes are likely to be affected equally; the female prevalence in some studies can probably be attributed to cosmetic reasons. It can occur and spread at any stage of life and is often associated with a positive family history. Up to 30 percent of patients have reported vitiligo in another family member. The lesion is characterized by discrete, pale-white macules, few or several in number, which tend to enlarge centrifugally over time. It is not contagious, nor is it a serious health problem. However, it can be troublesome in brown and black people as well as in white persons who tan deeply (skin phototype IV), and often leads to social embarrassment and psychological turmoil.
Continental Population Groups ; Female ; Humans ; Prevalence ; Triacetoneamine-N-Oxyl ; Vitiligo*

OBJECTIVE: The study was performed to evaluate whether thallium reinjection (RI) distinguishes viable from nonviable myocardium among myocardial segments which showed persistent perfusion defect (PD) in patients with acute myocardial infarction (AMI). MATERIALS AND METHODS: We studied 22 patients underwent PTCA after AMI. SPECT was performed in all patients using dipyridamole stress- 4 hour redistribution (RD) followed by 24 hour RI protocols. Dysfunctional segs were classified into 5 groups: 1) normal, 2) reversible, 3) mild to moderate PD, 4) severe PD and 5) reverse redistribution (RR). All patients underwent follow up echocardiography after 4 months to assess regional wall motion (WM) improvement such as a criteria of viable myocardium. RESULTS: A total of 127 segs with abnormal WM was analyzed. Of 74 segs with PD, 17 (23%) showed enhanced uptake after 24 hour RI. Five of 17 segs (29%) with PD that responded to RI with enhanced thallium uptake showed WM improvement. WM improvement were seen in the 24 of 57 segs (42%) not responding to RI. All four segs (100%) with RR that responded to RI showed improvement. WM improvement were not seen in the 5 of 8 segs (71%) with RR not responding to thallium RI. Eleven (73%) of 15 segs with mild-moderate PD after RI showed improvement, but 33% of segs with severe PD after RI did not showed improvement. Segs with mild-moderate PD after RI and fill in after RI showed improvement in comparison to segs with severe PD after RI(p<0.05). CONCLUSIONS: These data indicate that because only small proportion of PD showed further perfusion improvement after RI and predictive value by the uptake after RI was low, there was limited role of RI after myocardial infarction. Usefulness of RI could be found in segs showing RR responding to RI in AMI reflects viable myocardium.
Dipyridamole ; Echocardiography ; Follow-Up Studies ; Humans ; Myocardial Infarction* ; Myocardium ; Perfusion ; Thallium ; Tomography, Emission-Computed, Single-Photon

No abstract available.
Free Tissue Flaps* ; Head* ; Neck*