This is a case report and review of literature that deals with hemifacial microsomia corrected by costochondral graft, Lefort I osteotomy and bilateral intraoral sagittal split ramus osteotomy. Patient, 23 years old female, had visited to treat the esthetic problem due to a deviation of jaw. On the basis of clinical and radiographic examinations, she was diagnosed as hemifacial microsomia. First, costochondral graft was performed to bridge the defect between glenoid fossa and body of mandible. After 11 months,. Patient was performed a Lefort I osteotomy and bilateral intraoral sagittal split ramus osteotomy to create a symmetric jaw. Patient was satiesfied with final esthetics and there have been no evidence of infection ill now.
Esthetics ; Female ; Goldenhar Syndrome* ; Humans ; Jaw ; Mandible ; Osteotomy ; Osteotomy, Sagittal Split Ramus ; Transplants

No abstract available.
Humans ; Transplants*

It is. commonly assumed that nasorespiratory function can exert a dramatic effect upon the development of the dentofacial complex. Specially, it has been stated that chronic nasal obstruction leads to mouth breathing, which causes altered tongue and mandibular positions. If this occurs during a period of active growth, :the .outcome is development of the "adenoid facies". Such patients characteristically: manifest a vertically long lower third facial height, narrow alar bases, lip incompetence, a long and narrow maxillary arch and a greater than normal mandibular plane angle. But several authors have reported that so-called adenoid facies is not always associated with adenoids and mouth breathing, and that a particular type of dentition is not alwarys found in mouth breathers with or without adenoids. Some authors have believed adenoids lead to mouth breathing in cases with particular facial characteristics and types of dentition. We assumed that the ability to adapt to individual's neuromuscular complex is various. So, we compared the difference of influence of mouth breathing between childrens who have different facial types. This study included 60 patients and they were divided into three groups by Rickett's facial type. Their dentition and tongue position were compared. The results are as follows. 1. There is a significant difference in arch width of upper molars between different facial types. Especially dolichofacial type patients have narrowest arch width. 2. There is a significant difference in tongue position between different facial types. Especially dolichofacial type patients have lowest positioned tongue.
Adenoids ; Child ; Dentition* ; Facies ; Humans ; Lip ; Molar ; Mouth ; Mouth Breathing ; Nasal Obstruction ; Respiration* ; Tongue

Functional recovery after mandibular condyle fracture was a contradictory result of many authors. The treatment goal of condyle fracture has been directed primarily toward restoration of functional movement of the mandible. We selected some patients who requested functional therapy in many cases of condylar fracture, depend on pattern of fracture, patient's demand, occlusion, age. Without intermaxillary fixation, we induced the patients to rapid healing of temporomandibular function and normal mandibular protrusive, lateral movement as a result of early functional therapy by activator. So, the authors report the cases with review of concerned literature.
Humans ; Mandible ; Mandibular Condyle

1.050 patients who visited orthodontic dental department from 1983 to 1994, were surveyed on the yearly tendency of orthodontic patient distribution and state by means of Angle's classification. The results were as follows : 1. There was increased visiting rate of patient per year and higher visiting rate in female than in male. 2. 8-15 age group was 61.4% in total visiting patients and over 20 age group was 18.5%, under 7 age group was 8.1%. 3. Class I malocclusion was 42.2%, class II div 1 was 22.5%, class II-2 was 3.9%, class III was 29.1% and cleft lip & palate was 2.0% in total visiting patient. 4. As showed the living distribution, Namgu and Susunggu's patients were 43.7% of the total patients. 5. There was increased tendency for the number of the patient to be received orthognathic surgery.
Cleft Lip ; Dentistry* ; Female ; Humans ; Male ; Malocclusion* ; Orthodontics* ; Orthognathic Surgery ; Palate

The correlation between facial pain and/or headache in patients with chronic sinusitis and localized findings on paranasal sinus omputed tomography (CT) are poorly understood. So we prospectively evaluated the relationship of paranasal sinus pain symptoms with CT imaging. Fifty eight patients with headache and/or facial pain rated their pain in 9 areas at the time of CT scanning and 2 months after endoscopic sinus surgery (ESS). We scored the degree of air-fluid level, mucosal thickening, and mucus retention cysts using a grade scale of severity. The ostiomeatal unit, middle meatus and nasofrontal duct were also evaluated for patency. Bivariate analysis was performed to evaluate the relationship between patients' pain, that was improved after ESS and CT findings. Among 58 patients who had facial pain and/or headache at the time of CT scan, the pain improved in 51 patients after ESS. Bivariate analysis failed to show any relationship between pain symptoms and CT findings in 51 patients. This study suggests that findings on CT do not routinely correlate with the patients' symptoms of facial pain or headache. CT should therefore be reserved for delineating the anatomy and degree of sinus disease before surgical intervention.
Facial Pain ; Headache ; Humans ; Korea* ; Mucus ; Prospective Studies ; Sinusitis ; Tomography, X-Ray Computed

This study was to investigate the effects of a silk peptide, and prune and raspberry mixture on the body fat, serum lipid composition and fat distribution in Korean women during the time they received these supplements. During the 4 month period of this research (June to October, 2002), 75 women (average age 22.9 yr) were selected as subjects. Their nutrient intake was investigated by use of a questionnaire and the 24-hour recall method. Antropometric assessments of the subjects were investigated by using the SBIA Method (Segmental Bioimpedance Assay, Inbody 3.0). The results were as follows: their mean body weight was 59.3 kg, their mean body height was 161.7 cm and their mean Basal Metabolic Indices (BMI) was 22.7. The status of their dietary fiber intake significantly increased (p<0.05) after use of the supplements. Their body fat significantly decreased following the 3rd stage of supplementation (p<0.05), and their percent of body fat signiflcantly decreased after supplementation (p<0.05). Their triceps and suprailiac circumference significantly decreased following the 3rd stage of supplementation (p<0.05). Their waist circumferences and waist-hip ratios (WHR) significantly decreased after both the 2nd and 3rd stage of supplementation (p<0.05). Their total cholesterol significantly decreased following the 3rd stage of supplementation, as compared to their baseline results and those obtained following the 1st stage of supplementation (p<0.05). Their LDL-cholesterol and LDL/HDL ratios significantly decreased following the 3rd stage of supplementation, as compared to their baseline results and those obtained following the 1st stage of supplementation (p<0.05). Their 4-HNE and total antioxidant statuses significantly decreased following the 2nd and 3rd stage of supplementation, as compared to their baseline results and those obtained following the 1st stage of supplementation (p<0.05). Their 2nd stage supplementation results were significantly negatively correlated with their triceps measurements and WHR (p<0.05). Their 3rd stage supplementation results were significantly negatively correlated with their anterior thigh measurements (p<0.05). The above results show that prune, raspberry, silk peptide and dietary fiber supplementation to a routine diet improves body fat distribution, total cholesterol, and triglyceride levels. The decrease of abdominal fat and WHR were especially noteworthy. This implies a decrease of risk factors.
Abdominal Fat ; Adipose Tissue ; Body Composition ; Body Fat Distribution ; Body Height ; Body Weight ; Cholesterol ; Diet ; Dietary Fiber ; Female ; Humans ; Leptin* ; Risk Factors ; Silk ; Thigh ; Triglycerides ; Waist Circumference ; Waist-Hip Ratio ; Surveys and Questionnaires

We report a case of hypertensive heart failure with severe stenosis of the descending aorta. The patient had hypertension; however, he had not previously received any antihypertensive treatment. After receiving antihypertensive therapy for 2 weeks, he was admitted to our hospital for acute heart failure. Computed tomography (CT) and magnetic resonance imaging (MRI) showed severe arteriosclerotic stenosis of the descending aorta above the renal artery bifurcation. He underwent aortic resection and grafting. After surgery, his condition improved, and he was discharged.
Aorta ; Aorta, Thoracic* ; Arteriosclerosis ; Constriction, Pathologic* ; Heart Failure* ; Heart* ; Humans ; Hypertension ; Magnetic Resonance Imaging ; Renal Artery ; Transplants

BACKGROUND: Small cell lung cancer (SCLC) transformation during epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment in lung cancer has been suggested as one of possible resistance mechanisms. METHODS: We evaluated whether SCLC transformation or neuroendocrine (NE) differentiation can be found in the cell line model. In addition, we also investigated its effect on responses to conventional chemotherapeutic drugs of the SCLC treatment. RESULTS: Resistant cell lines to various kinds of EGFR-TKIs such as gefitinib, erlotinib, CL-387,785 and ZD6474 with A549, PC-9 and HCC827 lung adenocarcinoma cell lines were established. Among them, two resistant cell lines, A549/GR (resistant to gefitinib) and PC-9/ZDR (resistant to ZD6474) showed increased expressions of CD56 while increased synaptophysin, Rb, p16 and poly(ADP-ribose) polymerase were found only in A549/GR in western blotting, suggesting that NE differentiation occurred in A549/GR. A549/GR cells were more sensitive to etoposide and cisplatin, chemotherapeutic drugs for SCLC, compared to parental cells. Treatment with cAMP and IBMX induced synaptophysin and chromogranin A expression in A549 cells, which also made them more sensitive to etoposide and cisplatin than parental cells. Furthermore, we found a tissue sample from a patient which showed increased expressions of CD56 and synaptophysin after development of resistance to erlotinib. CONCLUSION: NE differentiation can occur during acquisition of resistance to EGFR-TKI, leading to increased chemosensitivity.
1-Methyl-3-isobutylxanthine ; Adenocarcinoma ; Blotting, Western ; Cell Line ; Cell Transformation, Neoplastic ; Chromogranin A ; Cisplatin ; Drug Resistance, Neoplasm ; Epidermal Growth Factor ; Etoposide ; Humans ; Lung ; Lung Neoplasms ; Parents ; Piperidines ; Poly(ADP-ribose) Polymerases ; Protein-Tyrosine Kinases ; Quinazolines ; Receptor, Epidermal Growth Factor ; Small Cell Lung Carcinoma ; Synaptophysin ; Erlotinib Hydrochloride