1.A Clinical Study on Myltiple Neurofibromatosis.
Kyung Sool KWON ; Soon Taek KIM ; Hou Suk SEONG
Korean Journal of Dermatology 1975;13(3):167-176
No abstract available.
Neurofibromatoses*
2.Distal femoral osteotomy for knee flexion contracture in residual poliomyelitis.
Kyung Un YOO ; In Kwon KIM ; Suk Joo LYU
The Journal of the Korean Orthopaedic Association 1992;27(3):651-657
No abstract available.
Contracture*
;
Knee*
;
Osteotomy*
;
Poliomyelitis*
3.The callotasis method of limb lengthening by orthofix.
Kyung Un YOO ; In Kwon KIM ; Suk Ju LYU
The Journal of the Korean Orthopaedic Association 1992;27(3):625-631
No abstract available.
Extremities*
;
Osteogenesis, Distraction*
4.The Effect of Overweight and Pregnancy on Endocrinologic Features and Glucose Metabolism in Patients with Polycystic Ovarian Syndrome.
Kyung Joo HWANG ; Kie Suk OH ; Sei Kwang KIM ; Hyuck Chan KWON ; Young Han PARK ; Jung In YANG ; Hee Suk RHYU
Korean Journal of Obstetrics and Gynecology 1999;42(3):606-613
OBJECTIVE: The purpose of this study attempts to determine the endocrinologic characteristics and changes in glucose metabolism before/during pregnancy according to different body weights in women with Polycystic ovarian syndrome (PCOS). METHODS: 94 women dia with PCOS were evaluated through measuring serum hormone levels and oral glucose tolerance tests preconceptionally and gestationally. RESULTS: In patients who were of normal weight showed significantly increased serum LH levels compared to those who were overweight (12.8+/-0.9 Vs. 7.1+/-0.8 mIU/ml, p= 0.000), and the serum levels of insulin was increased significantly in the overweight group (7.1+/-0.7 Vs. 15.2+/-2.8 ulU/ml, p= 0.000). the IGFBP-I (32.8+/-10.6 Vs. 8.3+/-2.5 ng/ml, p=0.034) and SHBG (55.8+/-4.2 Vs. 37.1+/-3.1 nmol/ml, p= 0.001) were significantly lower in the ovnweight group. The oral glucose tolerance test before/after pregnancy showed increased frequency of abnormal glucose metabolism, in both of the non-obese group (38.8%, 26,9%) and the obese group (64.2%, 53.9%) compared with normal population. CONCLUSION: It is thought that in the normal weight group with polycystic ovarian syndrome androgen production is stimulated in the theca cells by abnormally high LH secretion, while in the overweight group the hyperinsulinemia state which decreases the SHBG and IGFBP-I, lead to increase biologically active hee androgens and IGF-I and increase insulin binding to its receptor. And during/before pregnancy, women with PCOS showed that incidence of abnormal glucose metabolism was significantly increased in both of non-obese and obese groups.
Androgens
;
Body Weight
;
Female
;
Glucose Tolerance Test
;
Glucose*
;
Humans
;
Hyperinsulinism
;
Incidence
;
Insulin
;
Insulin-Like Growth Factor I
;
Metabolism*
;
Obesity
;
Overweight*
;
Polycystic Ovary Syndrome*
;
Pregnancy*
;
Theca Cells
5.Detection of human papillomavirus DNA using the polymerase chain reaction in paraffin-embedded biopsy specimens of condylomata acuminata.
Suk Joo CHOI ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1993;31(4):508-516
BACKGROUND: Condylomata acuminata is a sexually transmitted cisease which is caused by the human papillomavirus(HPV). The types of HPV causing condylomata acuminata are HPV 6,11,16,18. HPV 16 and 18 are related to anogenital carcinoma. OBJECTIVE: The goals of this study were to determine the types cif HPV in condylomata acuminata, and to investigate the relationship between condylomata acuminata and anogenital carcinoma. MEHTODS: Polymerase chain reaction and restriction fragment le igth polymorphisms were performed in the paraffin-embedded tissues of 17 cases of condylomata acciminata. RESULTS: HPV DNA was detected in all of 17 cases of condylomata accuminata tested. HPV 6 and 11 were found in 53% (9/17) and 41% (7/17) of the samples, respectiiely. HPV 16 and/or 18, which are related to anogenital carcinovia, were not detected, except in one case in which HPV 16 was found to be superimposed with HPV 6 and 11. CONCLUSION: These results suggest that most of condylomata acumirata are caused by HPV 16 and 11, and there is not so much risk of this disease transforming into the aiogenital carcinoma.
Biopsy*
;
Condylomata Acuminata*
;
DNA*
;
Human papillomavirus 16
;
Human papillomavirus 6
;
Humans*
;
Polymerase Chain Reaction*
6.Preoperative Quality of Life in Patients with Gastric Cancer.
Hyoam SUK ; Oh Kyung KWON ; Wansik YU
Journal of Gastric Cancer 2015;15(2):121-126
PURPOSE: We evaluated the socio-personal and clinical factors that can affect preoperative quality of life to determine how to improve preoperative quality of life in patients with gastric cancer. MATERIALS AND METHODS: The preoperative quality of life data of 200 patients (68 females and 132 males; mean age 58.9+/-12.6 years) with gastric cancer were analyzed according to socio-personal and clinical factors. The Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core (QLQ) 30 and the EORTC QLQ-STO22, a gastric cancer-specific module, were used to assess quality of life. Patients were asked to complete the questionnaire preoperatively by themselves. RESULTS: Patients with a higher academic background and stage I disease tended to have higher global health status scores. Highly educated younger men had better physical functioning scores. Highly educated and well-nourished patients with stage I cancer had higher role functioning scores. Married patients had better emotional scores. The symptom scales were affected by sex, age, education level, nutrition, and cancer stage. CONCLUSIONS: Preoperative quality of life in patients with gastric cancer can be improved by nutritional support and treatment of symptoms caused by disease progression. Psychological support may be helpful for patients with a poor quality of life.
Disease Progression
;
Education
;
Female
;
Health Records, Personal
;
Humans
;
Male
;
Nutritional Support
;
Preoperative Period
;
Quality of Life*
;
Stomach Neoplasms*
;
Weights and Measures
;
Surveys and Questionnaires
7.A Case of Ichthyosiform Sarcoidosis.
Suk Joo CHOI ; Eul Hee HAN ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1994;32(1):172-176
Although acquired ichthyosis has been associated with a number of systemic illnesses, an association with sarcoidosis has rarely been reported. We report a patient with aquired ichthyosis of the lower and upper extrimities whose diagnosis of cutaneous sarcoidosis was confirmed by histologic examination. Systemic involvement in the patient revealed occular, pulmonary and nerve disease. A diagnosis of sarcoidosis must be considered when a patient presents with acquired ichthyosis.
Diagnosis
;
Humans
;
Ichthyosis
;
Sarcoidosis*
9.The Effects of the Taping Therapy on Range of Motion, Pain and Depression in Stroke Patient.
Journal of Korean Academy of Nursing 2003;33(5):651-658
PURPOSE: The purpose of this study was to test the effect of Taping therapy on Range of Motion, pain, and depression in stroke patients in the home without complete recovery as a means of nursing intervention. METHOD: Twenty seven subjects out of fifty four people who were attending in the stroke self-help group in one community health center in S city were asked to participate in this Quai-experimental study. The Taping therapy was a method that stick to the illness area and the point of pressure pain, the elastic and cross tape without medicine treatment with domestic products. Nursing intervention was independently completed by researcher once a week over two period of 12 weeks from September 2001 to March 2002 year. Data were analyzed using the SPSS win. The homogeneity between the experimental group and control grouup was test by x2 and t-test. The difference of experimental before and after were tested by the unpaired t-test. RESULT: The shoulder joint flexion and abduction, the elbow joint flexion and extension, the hip joint flexion, and the flexion of knee joint in the ROM of the experimental group were significantly improved over those of the control group. In difference of pain, rest and painful movement, the experimental group were significantly decreased over those of the control group. The difference of depression in experimental before and after was significantly decreased in the experimental group over those of the control group. CONCLUSION: The Taping therapy intervention proved effect pain relief and depression decrease as well as promote of range of motion.
10.Measurement of Autoantibodies by ELISA Kits.
Hyun Kyung KIM ; Hyon Suk KIM ; Oh Hun KWON ; Soo Kon LEE
Korean Journal of Clinical Pathology 1997;17(2):321-330
BACKGROUND: The detection of specific autoantibodies in the sera of patients with systemic rheumatic diseases plays a key role in the differential diagnosis. Enzyme-linked immunosorbent assays (ELISA) is known as sensitive and semiquantitative method to detect autoantibodies and ELISA kits using a recombinant fusion protein as antigen have been developed. So, various commercial ELISA have recently become available in a diagnostic laboratory. We investigated the clinical value of antinuclear autoantibodies using commercial ELISA kits. METHODS: The serum of 90 patients were tested for autoantibodies to SSA/Ro, SSB/La, nRNP/Sm and Sm antigens by ELISA using four commercial kits, EL-ANA(TM) (TheraTest, IL, USA), DIASTAT(TM)(SHIELD, DUNDEE, UK), QUANTALit(TM) (INOVA, CA, USA), Varelisa(TM) (elias, WI, USA). We evaluated the clinical usefulness of panel test of Varelisa(TM) in the diagnosis of systemic rheumatic diseases. RESULTS: The concordance rates of four ELISA kits for autoantibodies to SSA/Ro, SSB/La, RNP/Sm and Sm antigens were 83.6%, 74.5%, 87.5% and 80.0%, respectively. Using panel test of Varelisa(TM), positive rates of autoantibodies to Ul-snRNP, nRNP/Sm, Sm, SSA/Ro, SSB/La, Scl-70, CENP and Jo-1 antigens in SLE were 30.0, 40.0, 33.3, 46.7, 20.0, 20.0, 10.0, and 0%, respectively. Of 30 patients with SLE, 16 (53.3%) were positive for 2 or more antibodies. CONCLUSIONS: EL-ANA(TM), QUANTALite(TM) and Varelisa(TM) show more positive rates than DIASTAT(TM). The difference in the positive rates among four commercial ELISA kits may come from the different antigen sources. The panel test of 8 autoantibodies using Varelisa(TM) ELISA kit offers discriminative power and enhances the specificity of the assay in patients who lack clear evidence of clinically definite autoimmune disease.
Antibodies
;
Autoantibodies*
;
Autoimmune Diseases
;
Diagnosis
;
Diagnosis, Differential
;
Enzyme-Linked Immunosorbent Assay*
;
Histidine-tRNA Ligase
;
Humans
;
Rheumatic Diseases
;
Sensitivity and Specificity
;
Staphylococcal Protein A