Follow-up examination was done in 28 eyes of 28 leprosy patients in So-Rok Do national leprosarium that were operated on for complicated cataract six months ago. Their visions were then hand movement or light perception. Six months later results were as follow; (1) 15 eyes have more than 0.1 of corrected vision (Table 1). (2) 9 eyes have corrected vision from finger counting to 0.05 (Table 2). (3) 1 eye has vision of hand movement and 3 eyes were blind. (Table 3).
Cataract* ; Fingers ; Follow-Up Studies ; Hand ; Humans ; Leprosy*

Among 8,796 patients seen in the department of ophthalmology Yonsei University Medical Center from August 1. 1965 to July 31, 1968 there were 1,919 who were seen because of refractive error. These were selected for classification and special statistical study. In 1962 we reported a similar study of 2,004 patients having errors in refraction among a total of 9,716 patients seen in the same department from August 1. 1958 to July 31. 1961. The findings of the more recently studied group are compared with the study made in 1962. 1. 1,919 out of 8.796 patients seen in the department of ophthalmology had errors in refraction (21.8%). 2. 2,932(76.3%) had refractive error of the myopic (including simple myopic astigmatism) type. 740(19.4%) were hyperopic (had simple hyperopic astigmatism). The others had a mixed astigmatism. 3. 56.5% of the total group studied had astigmatism. 4. The highest incidence of refractive errors was found between 11 and 20 years of age. The older patients had a low incidence. 5. There was no relationship between sex and the incidence of refractive error. 6. Among the total number of refractive errors 55.9% were found to be in myopic patients who had less than a -3.00 diopter error. 18.9% were found among hyperopic patients who had less than a +3.00 diopter error. 7. Among the three types of astigmatic errors seen 970 cases(44.7%) were "with the rule"; 864 cases(39.8%) were "against the rule"; and 336 cases (15.5%) were "oblique". 8. 9.6% of the total refractive errors were those of different types of anisometropia. The most commanly seen type was that of compound myopic anisometropia. The next type seen was compound hypo eropic anisometropia and the least frequently seen type was mixed anisometropia. 9. When the results of the present study were compared with those found in 1962 there were no significant differences found between the two groups.
Academic Medical Centers ; Anisometropia ; Astigmatism ; Classification ; Humans ; Incidence ; Ophthalmology ; Refractive Errors ; Statistics as Topic

Between Oct. 1965 and Oct. 1970 467 eyes (450 patients) which recieved Sr90 (beta-ray) irradiation postoperatively were observed clinically at Severance hospital. 1) Among 467 eyes (450 patients), 321 eyes (68.7%) were referred to this hospital for postoperative beta-ray irradiation only (Fig.1). 2) 4500 rep of Sr90 were given to each eye in three equally divided doses. One 1st does was given about 24hours after surgery and the other two doses were given at one week inteintervals. 3) There was no significant sex difference in the number of patients-male (215 patients) and female (235 patient). 4) The oldest patient was 82 years and the yougest 16. 5) The greatest number of patients were between 31 and 40 year old (34.2%) and only one was over 81 year old (0.2%). 6) 230 left eyes were involved and 203 right eyes 17 patients had pterygium bilaterally (34 eyes). 7) 42 eyes had recurrent pterygium, there was no sex relationship in number of recurrences and no difference between right and left eyes developing recurrent pterigia. 8) Among 467 eyes which received post operatives sr90 irradiation, the incidence of recurrence was 2.8% (9 eyes).
Adult ; Aged, 80 and over ; Female ; Humans ; Incidence ; Pterygium* ; Recurrence ; Sex Characteristics

Between Oct. 1965 and Oct. 1970 467 eyes (450 patients) which recieved Sr90 (beta-ray) irradiation postoperatively were observed clinically at Severance hospital. 1) Among 467 eyes (450 patients), 321 eyes (68.7%) were referred to this hospital for postoperative beta-ray irradiation only (Fig.1). 2) 4500 rep of Sr90 were given to each eye in three equally divided doses. One 1st does was given about 24hours after surgery and the other two doses were given at one week inteintervals. 3) There was no significant sex difference in the number of patients-male (215 patients) and female (235 patient). 4) The oldest patient was 82 years and the yougest 16. 5) The greatest number of patients were between 31 and 40 year old (34.2%) and only one was over 81 year old (0.2%). 6) 230 left eyes were involved and 203 right eyes 17 patients had pterygium bilaterally (34 eyes). 7) 42 eyes had recurrent pterygium, there was no sex relationship in number of recurrences and no difference between right and left eyes developing recurrent pterigia. 8) Among 467 eyes which received post operatives sr90 irradiation, the incidence of recurrence was 2.8% (9 eyes).
Adult ; Aged, 80 and over ; Female ; Humans ; Incidence ; Pterygium* ; Recurrence ; Sex Characteristics

PURPOSE: A colorectal carcinoma is the fourth most common malignancy in the world. Unfortunately, only approximately 20% of the liver metastases are resectable at the initial presentation. Neoadjuvant chemotherapy has been used for downsizing in unresectable disease. In addition, the use of newer biologic agents, such as cetuximab and bevacizumab, has much improved responses in patients with unresectable colorectal liver metastases. The aim of this study was to report on patients who had received a curative resection following neoadjuvant chemotherapy including a molecularly targeted agent for unresectable colorectal liver metastases. METHODS: Following the neoadjuvant chemotherapy using cetuximab plus FOLFIRI (irinotecan and infused fluorouracil plus leucovorin) or bevacizumab plus FOLFOX (oxaliplatin and infused fluorouracil plus leucovorin), 10 patients with initially unresectable colorectal liver metastases underwent a curative surgical resection between September 2005 and June 2007. RESULTS: One patient underwent a right lobectomy, three patients a segmentectomy and five a wedge resection with or without radiofrequency ablation. With a median postoperative follow-up of 14 months (range, 1 to 22 months), five recurrences (50%) occurred. The common toxic effects were grade 2/3 skin toxicity (60%), grade 4 hematologic toxicity (20%), grade 3 gastrointestinal toxicity (10%), and grade 3 neurologic toxicity (10%). CONCLUSIONS: Our preliminary data suggests that neoadjuvant chemotherapy including a molecularly targeted agent may improve resectability in patients with initially unresectable colorectal liver metastases although a high recurrence rate exists. Randomized prospective studies comparing neoadjuvant chemotherapy including a targeted agent in cases of unresectable colorectal liver metastases are warranted.
Antibodies, Monoclonal, Humanized ; Bevacizumab ; Cetuximab ; Colorectal Neoplasms ; Fluorouracil ; Follow-Up Studies ; Humans ; Liver ; Mastectomy, Segmental ; Neoplasm Metastasis ; Recurrence ; Skin

PURPOSE: Colorectal cancer patients with liver-confined metastases are classified as stage IV, but their prognoses can differ from metastases at other sites. In this study, we suggest a novel method for risk stratification using clinically effective factors. MATERIALS AND METHODS: Data on 566 consecutive patients with colorectal liver metastasis (CLM) between 1989 and 2010 were analyzed. This analysis was based on principal component analysis (PCA). RESULTS: The survival rate was affected by carcinoembryonic antigen (CEA) level (p < 0.001; risk ratio, 1.90), distribution of liver metastasis (p=0.014; risk ratio, 1.46), and disease-free interval (DFI; p < 0.001; risk ratio, 1.98). When patients were divided into three groups according to PCA score using significantly affected factors, they showed significantly different survival patterns (p < 0.001). CONCLUSION: The PCA scoring system based on CEA level, distribution of liver metastasis, and DFI may be useful for preoperatively determining prognoses in order to assist in clinical decisionmaking and designing future clinical trials for CLM treatment.
Carcinoembryonic Antigen ; Colorectal Neoplasms ; Humans ; Liver* ; Neoplasm Metastasis* ; Odds Ratio ; Passive Cutaneous Anaphylaxis ; Principal Component Analysis ; Prognosis ; Survival Rate