1.Comparison of Diagnostic Accuracy in Uterine Pathology among HSG, Hysteroscopy, and Sono-Hysterography.
Sun Hee CHA ; Jung Kyo CHOE ; You Me LEE ; Wee Hyun LEE ; Kyung Sub CHA
Korean Journal of Obstetrics and Gynecology 1997;40(8):1662-1668
Hysterosalpingography and Hysteroscopy have been used for the detection of intraute-rine pathology such as polyps, submucous myomas, intrauterine adhesion and endometrial hyperplasia or cancer. Recently the ultrasound has also been utilized for the detection of uterine pathology. Therefore the purpose of this study was to evaluate the diagnostic efficacy of SonoHysterography in detection of intrauterine pathology compared with HSG and Hysteroscopy. 32 patients underwent Sono-Hysterography and Hysteroscopy for the evaluation of the uterine pathology from september 1995 to January 1996. Nine of 32 patients had infertility problem and HSG performed prior to Sono-Hysterography and Hysteroscopy. The results are as follows : 1. The patients' ages ranged from 20 to 50 years(median 37.9). 2. All 9 patients with infertility who had positive HSG findings in uterine cavity showed the intrauterine pathology in Sono-Hysterography as well as Hysteroscopy. The detail findings are as follows :septated uterus(n=2), intrauterine adhesion :IUA(n=3), endometrial polyp(n=3), and IUA combined endmetrial hyperplasia(n=1). 3. Twenty two of 23 patients with abnormal uterine bleeding showed the intrauterne pathology and one patient had negative finding in Sono-Hysterography. However, Hysteroscopy revealed positive intrauterine pathology in 22 patients who had abnormal uterine bleeding. One patients who had positive finding in Sono-Hysterograply showed negative by Hysterography. In contrast, one patient who had negative finding in Sono-Hysterography had positive uterine pathology with polyp in Hysteroscopy. The histologic pathology in all 23 patients reported endometrial polyp(n=12), placental polyp(n=2), submucous myoma(n=1), endometrial hyperplasia(n=5), endometrial cancer(n=1), normal endometrial finding(n=2). 4. Sono-Hysterography, therefore, has a sensitivity and positive predictive value of 96.6%, 93.5% respectively. Our study showed a positive Sono-Hysterography is very predictive of the intrauterine pathology. Sono-Hysterography is safe, quick and minimal invasive procedure. So it is an invaluable technique in the evaluation of uterine cavity.
Endometrial Hyperplasia
;
Female
;
Humans
;
Hysterosalpingography
;
Hysteroscopy*
;
Infertility
;
Myoma
;
Pathology*
;
Polyps
;
Ultrasonography
;
Uterine Hemorrhage
2.Placetnal Findings of Septic Abortion Caused by Listeria Monocytogenes: A case report.
Kyu Rae KIM ; Hee Mo KIM ; Joo Yeon CHO ; Kyung Sub CHA
Korean Journal of Pathology 1991;25(4):387-391
Since human listeriosis was firstly described by Nyfeldt in 1929, Listeria monocytogenes as a cause of septic abortion has been well known. It primarily affects pregnant woman and neonates, the elderly, and persons with immune-system dysfunction due to immunosuppressive drugs, malignant tumors or AIDS. Although several large epidemic listeriosis have been reported in the English literatures, it is still an underdiagnosed and underreported cause of congenital sepsis and septic abortion, because it is not always easy to isolate the organism in culture. There are 17 cases reports of Listeria monocytogenes infection in Korea, however, most of which were described about the bascteriologically proven cases. We describe placental findings of a septic abortion caused by Listeria monocytogenes at 15 weeks gestation in a 23-year-old primigravida woman. Placental examination showed characteristic and relatively specific patterns of granulomatous microabscesses composed of necrotic nuclear debris in the center and surrounding epithelioid histocytes enmeshed in fibrin between the acutely inflamed villi. There were numerous gram positive bacilli on Brown-Brenn stain.
Pregnancy
;
Female
;
Infant, Newborn
;
Humans
3.Placental Site Nodules & Plaques: A clinicopathologic analysis of 14 cases.
Kyu Rae KIM ; Sun Won HONG ; Kyung Sub CHA ; In Pyong KWAK ; Tae Ki YOON
Korean Journal of Pathology 1992;26(1):53-61
Placental site nodules and plaques have been recently described to designated single or multiple, well-circumscribed, rounded lesions at the placental site, composed of viable or degenerating intermediate trophoblastic cells and extensive hyalinization between the cells. We described clinicopathologic findings of 14 cases of placental site nodules and plaques. The age of 14 patients ranged from 25 to 39(average 33) years and all of them had been pregnant in the past. Ten of them presented with vaginal spotting, which was preceded by recent pregnancy in only 3 cases. Three patients presented with secondary infertility and one with secondary infertility and vaginal spotting. Urine pregnancy tests were negative in all 14 cases at the time of presentation. Ultrasonographic examination disclosed abnormalities in only 3 cases and the remaining cases were normal. Hysterosalpingography was performed in 3 patients who presented with 2 degrees infertility and revealed moderate to severe intrauterine adhesions. Microscopically, chronic endometritis of varying degrees evidenced by plasma cells and eosinophiles were present in all cases and these were more prominent in the vicinity of the lesions. It is presumed that the placental site nodules and plaques are not sloughed at the time of menstruation and it may cause chronic endometritis or intrauterine adhesions at any time after previous delivery.
Pregnancy
;
Female
;
Humans
4.Giant Chorioangioma of the Placenta as a Cause of Fetal Hydrops and Neonatal Death: A case report.
Kyu Rae KIM ; Kyu Hyung LEE ; Tae Ki YOON ; In Kyu KIM ; Kyung Sub CHA
Korean Journal of Pathology 1992;26(5):524-529
We described a giant chroioangioma of the placenta that caused premature rupture of membranes at 31 weeks of gestation in a 31-year-old primiparous woman and a subsequent neonatal death of the baby. The placental mass, weighing 820 gm and measuring 21.5x15x4.5 cm, was easily shelled out from a edematous 1280 gm-placenta. The mass had a thin fibrous capsule and a solid fibromatous appearance. The infant, weighed 2175 gm, appeared edematous oon the whole body and had Apgar scores of 4 and 5 at 1 and 5 minutes respectively. The baby expired 4 days after birth due to high output cardiac failure and respiratory failure. Postmortem examination revealed markedly dilatated umbilical vein, inferior vena cava and right atrium with patent froamen ovale, congestive hepatosplenomegaly, pulmonary hemorrhages, and meconium aspiration pneumonia. Microscopically, the mass revealed a variety of histologic patterns, reflecting entire spectrums of villous vasculogenesis from loose myxomatous connective tissue and undifferentiated hemangioblastic cell nests to well-developed capillaries with hematopoietic cells in the lumen.
Infant
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Male
;
Female
;
Infant, Newborn
;
Humans
5.Delivery of the elderly primipara.
Joo Yeon CHO ; Kwang Yul CHA ; Jung Jin KOO ; Moon Jong KIM ; Dong Hee CHOI ; Kyung Sub CHA
Korean Journal of Obstetrics and Gynecology 1991;34(9):1313-1321
6.The usefulness of CT for the preoperative evaluation of lymph node in patients with gastric cancer.
Kyung Myung SON ; Hyun Kwon HA ; Eun Suk CHA ; Cho Hyun PARK ; In Chul KIM ; Kyung Sub SHINN ; Yong Whee BAHK
Journal of the Korean Radiological Society 1992;28(5):728-732
An accurate preoperative evaluation of lymph nodes(LNs) in gastric cancer is a prerequisite for successful surgery and favorable prognosis. We retrospectively analyzed the Ct accuracy in perigastric LN localization and LN staging of gastric cancer as well as the size criteria for the metastasized LN in 64 patients who hed undergone a surgery for gastric cancer. The results of perigastric LNs evaluation by CT are as follows; sensitivity 67%(64/95), specificity 90%(839/929), accuracy 88%(903/1024). Of 95 pathologically metastasized LN groups, 66 could be retrospectively identified on Ct scans(69%). In LN staging, CT was correct in 60%(38/64), overstaged in 32%(21/64), and understaged in 8%(5/64). The perigastric LN groups which were easily localized on CT were #3, 7, 8, and 13. The mean size of metastasized LNs on CT according to the I.N group was #3 (13mm), #4(9mm), #6 (10mm), #7(10.5mm), #8 (10mm), #9 (11mm), #13 (9mm).
Humans
;
Lymph Nodes*
;
Prognosis
;
Retrospective Studies
;
Sensitivity and Specificity
;
Stomach Neoplasms*
7.Clinical evaluation of treatment with fluconazole in patients with vaginal candidiasis.
Jin Sub AHN ; Kyung Yeun CHA ; Jae I YANG ; Hee Sub RHEE ; Soo Kyeong HWANG ; Byung Chan OH ; Jong Duk KIM
Korean Journal of Obstetrics and Gynecology 1992;35(11):1613-1620
No abstract available.
Candidiasis*
;
Fluconazole*
;
Humans
8.A Brown-Sequard Syndrome Resulting from a Ruptured Cervical Disc Herniation: A Case Report.
Moon Soo SHIN ; Bong Sub CHUNG ; Hun Kyu CHOI
Journal of Korean Neurosurgical Society 1996;25(11):2365-2367
We present a case of Brown-Sequard syndrome due to a massive cervical disc herniation at C5/6 level, presenting sings of sudden and severe spinal cord compression. The lesion was diagnosed by MRI and herniated cervical disc was removed under the surgical microscope via anterior route. The result of operation was good. A brief review of the literature is given.
Brown-Sequard Syndrome*
;
Magnetic Resonance Imaging
;
Spinal Cord Compression
9.Body stalk anomaly: a case report.
Soon Ae JUN ; Myong Ock AHN ; Seung Sook LEE ; Je G CHI ; Kyung Sub CHA
Journal of Korean Medical Science 1991;6(2):177-181
A case is presented of an amnionic rupture sequence which led to massive fetal ventral herniation and lordoscoliosis. Characteristic ultrasonographic findings of an omphalocele, fetal attachment to the placenta, and the absence of free-floating umbilical cord were observed.
Abnormalities, Multiple/*etiology/ultrasonography
;
Adult
;
Amnion
;
Female
;
Fetal Membranes, Premature Rupture/*complications
;
Gestational Age
;
Hernia, Umbilical/etiology
;
Humans
;
Infant, Newborn
;
Male
;
Pregnancy
;
Umbilical Cord/abnormalities
10.Comparison of Maternal Serum Screening Test Efficacy for Down Syndrome.
Chung No LEE ; Yong Won LEE ; Hye Sun JUN ; Suk Whan LEE ; Kyung Lyul KIM ; Kwang Eun CHA ; Kyung Sub CHA ; Jin Young BAEK
Korean Journal of Obstetrics and Gynecology 1997;40(4):721-731
Maternal serum alpha-feto protein(MSAFP) screening test has provided high sensitivity and specificity in detecting neural tube defects(NTD). Approximately 80~90% of NTD can be identified by this screening test.Prospective studies have shown that low levels of MSAFP can be used for Down syndrome screening test, but the detection rate for Down syndrome in combination with age is only 20% in younger women, making this screening test relatively insensitive. However recently some studies have suggested that the triple marker test with MSAFP, unconjugated estriol, beta-human chorionic gonadotropin achieved higher detection rate for Down syndrome. The purpose of present study is to compare the positive predictive values of both MSAFP and Triple test. We had 6,436 cases of MSAFP test during the year of 1994 and 7,077 cases for triple test during the year of 1995. We analyzed data with positive results by screening both tests, since our purpose is to compare positive value. The number of positive results were 290(triple test) and 206(AFP) respectively. With this study, we concluded that positive predictive value of triple marker test is 4.17 times greater than of the MSAP test.
Chorionic Gonadotropin
;
Down Syndrome*
;
Estriol
;
Female
;
Humans
;
Mass Screening*
;
Neural Tube
;
Sensitivity and Specificity