2.A Cytogenetic Study of Amenorrhea.
Kyung Soon LEE ; Jung Ho HAN ; Shin Yong MOON
Korean Journal of Fertility and Sterility 1999;26(3):467-474
OBJECTIVEs: Cytogenetic investigations were carried out on 770 women with primary (n=560) and secondary amenorrhea (n=210) to determine the frequency of chromosomal or genetic causes of amenorrhea. MATERIALS AND METHODS: In 770 women with primary amenorrhea (n=560) and secondary amenorrhea (n=210), chromosomal analysis were performed. RESULTS: 1) The most prevalent age group is 16-20 years of age group with primary amenorrhea and 26-30 years of age group with secondary amenorrhea. 2) Out of 560 cases of primary amenorrhea, 343 cases (61.3%) had the normal chromosome constitution and 217 cases (38.7%) had the abnormal chromosome constitution including 46,XY. 3) In 217 cases of abnormal chromosome of primary amenorrhea, 57 cases (26.3%) had 45,X and 34 cases (15.8%) had the 46,XY, 24 cases (11.0%) had 45,X/46,X,i (Xq), 23 cases (10.6%) had 45,X/46,X,+mar and 14 cases (6.6%) had 45,X/46,XY. 4) Out of 210 cases of secondary amenorrhea, 181 cases (86.2%) had the normal chromosome constitution and 29 cases (13.8%) had 45,X/46,XX. CONCLUSION: High percentage of chromosomal abnormalities was diagnosed in primary amenorrhea and most of them were sex chromosome anomalies. In secondary amenorrhea, the prevalence was lower than primary amenorrhea, so a preselection of patients with secondary amenorrhea for cytogenetic investigations seems to be necessary.
Amenorrhea*
;
Chromosome Aberrations
;
Constitution and Bylaws
;
Cytogenetics*
;
Female
;
Humans
;
Prevalence
;
Sex Chromosomes
3.A Cytogenetic Study of Recurrent Spontaneous Abortion.
Kyung Soon LEE ; Jung Ho HAN ; Sun Kyung OH ; Shin Yong MOON
Korean Journal of Fertility and Sterility 1999;26(3):475-481
OBJECTIVE: The purpose of this investigation is to determine the frequency of chromosomal or genetic causes of recurrent spontaneous abortion. METHODS : A cytogenetic study was made in of 921 couples for 13 years from January 1984 to December 1997 in which the woman was ascertained to have had two or more spontaneous abortions at our Cytogenetic Laboratory, Institute of Reproductive Medicine and Population, Seoul National University. RESULTS : The overall incidence of chromosome anomaly was 80 out of 921 (8.7%). There were 34 cases (3.69%) of reciprocal balanced translocation and 13 cases (1.41%) of Robertsonian translocation. Also 17 cases (1.85%) of inversion and 5 cases (0.54%) of X chromosome mosiacism was observed. In the case of reciprocal balanced translocation, chromosome 8,6,7,13 were preferentially involved over others. And in the case of Robertsonian translocation, chromosome 13 was preferentially involved. CONCLUSION: Our study demonstrates that cytogenetic analysis is indicated in couples with 2 or more spontaneous abortion and about half of these disorders are reciprocal balanced or Robertsonian translocations.
Abortion, Spontaneous*
;
Chromosomes, Human, Pair 13
;
Cytogenetic Analysis
;
Cytogenetics*
;
Family Characteristics
;
Female
;
Humans
;
Incidence
;
Pregnancy
;
Reproductive Medicine
;
Seoul
;
X Chromosome
4.Steroid receptor profiles in human breast cancer and comparison of methodology for cytosolic procurement.
Jung Woon LEE ; Oh Hun KWON ; Kyung Soon SONG ; Kyung Ja RYU
Korean Journal of Clinical Pathology 1991;11(2):309-318
No abstract available.
Breast Neoplasms*
;
Breast*
;
Cytosol*
;
Humans*
;
Receptors, Steroid*
5.Anaerobic bacteria isolated from the clinical specimens during the period of 1983 to 1992.
Ahn Na LEE ; Young Sook KANG ; Kyung Won LEE ; Yoon Seob JUNG ; Kyung Soon SONG
Korean Journal of Infectious Diseases 1993;25(1):9-17
No abstract available.
Bacteria, Anaerobic*
6.Clinical diagnosis of cervical tuberculous lymphadenitis.
Jeong Pyo BONG ; Woo Kyung JUNG ; Dong Hak JUNG ; Soon Il PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(5):657-663
No abstract available.
Diagnosis*
;
Tuberculosis, Lymph Node*
7.A case of Kimura's disease.
Jeong Pyo BONG ; Woo Kyung JUNG ; Seung Kwon KIM ; Soon Hee JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):940-945
No abstract available.
8.Ultrastructural observation of human neutrophils during apoptotic cell death triggered by Entamoeba histolytica.
Seobo SIM ; Kyeong Ah KIM ; Tai Soon YONG ; Soon Jung PARK ; Kyung il IM ; Myeong Heon SHIN
The Korean Journal of Parasitology 2004;42(4):205-208
Neutrophils are important effector cells against protozoan extracellular parasite Entamoeba histolytica, which causes amoebic colitis and liver abscess in human beings. Apoptotic cell death of neutrophils is an important event in the resolution of inflammation and parasite's survival in vivo. This study was undertaken to investigate the ultrastructural aspects of apoptotic cells during neutrophil death triggered by Entamoeba histolytica. Isolated human neutrophils from the peripheral blood were incubated with or without live trophozoites of E. histolytica and examined by transmission electron microscopy (TEM). Neutrophils incubated with E. histolytica were observed to show apoptotic characteristics, such as compaction of the nuclear chromatin and swelling of the nuclear envelop. In contrast, neutrophils incubated in the absence of the amoeba had many protrusions of irregular cell surfaces and heterogenous nuclear chromatin. Therefore, it is suggested that Entamoeba-induced neutrophil apoptosis contribute to prevent unwanted tissue inflammation and damage in the amoeba-invaded lesions in vivo.
Animals
;
Apoptosis/*physiology
;
Entamoeba histolytica/*physiology
;
Host-Parasite Relations/physiology
;
Humans
;
In Vitro
;
Neutrophils/physiology/*ultrastructure
;
Research Support, Non-U.S. Gov't
9.Laparoscopic resection of a appendiceal mucocele.
Young Tae JU ; Soon Tae PARK ; Woo Song HA ; Soon Chan HONG ; Young Joon LEE ; Eun Jung JUNG ; Chi Young JUNG ; Sang Ho JEONG ; Sang Kyung CHOI
Journal of the Korean Surgical Society 2011;80(Suppl 1):S21-S25
Laparoscopic resection of appendiceal mucoceles has recently been described, but the safety and efficacy are controversial. We present two cases of laparoscopic mucocelectomies involving 14 and 15 cm cystic masses originating from the appendix. The laparoscopic mucocelectomies were performed using four ports. From the beginning of the procedure, a laparoscopic bag was used to safely contain the mucocele, prevent rupture of the mucocele, and retract the mucocele. An endoscopic stapling device was used to transect the base of the cecum. Minimal handling was achieved by gravity and with the use of laparoscopic instruments. Laparoscopic appendectomies are widely performed for acute appendicitis, but laparoscopic resection is not routinely performed for an appendiceal mucocele because of the risk of perforation and subsequent pseudomyxoma peritonei. We report two cases of laparoscopic appendiceal mucocelectomies, which were performed safely with laparoscopic instruments and minimal manipulation.
Appendectomy
;
Appendiceal Neoplasms
;
Appendicitis
;
Appendix
;
Cecum
;
Gravitation
;
Handling (Psychology)
;
Laparoscopy
;
Mucocele
;
Pseudomyxoma Peritonei
;
Rupture
10.Development of an E-learning Education Program for Preventing Nursing Errors and Adverse Events of Operating Room Nurses.
Jung Soon KIM ; Myung Soo KIM ; Sun Kyung HWANG
Journal of Korean Academy of Adult Nursing 2005;17(5):697-708
PURPOSE: This study was to develop, implement, and evaluate an e-learning education program for improving practical knowledge and preventing nursing errors and adverse events of nurses working in the operating room (OR). METHOD: The e-learning program was developed and evaluated according to the following processes: 1) preparation phase 2) implementation phase 3) evaluation phase. In evaluation phase, the effectiveness was analyzed based on the Kirkpatrick's model. RESULTS: The e-learning program consisted of OR basic nursing skills and techniques and nursing activities' manual based on the categories of nursing errors: surgical operation preparation, nursing skills and techniques, environment management, patient safety and comfort, and patient monitoring. The program was provided through on-line, http:// cafe.daum.net/pnuhorn, for 4 weeks. The mean score(percent) of participants' satisfaction was 21.24+/-1.71(68.2%). Their total knowledge level was significantly improved(Z=-3.00, p=.003) and specifically in the category of environment management(Z=-3.77, p<.001) and patient monitoring(Z=-2.46, p=.014). The occurrence of nursing errors or adverse events was a little decreased, but not statistically significant(Z= -3.10, p=.756). CONCLUSION: E-learning for nurses is one way of effective and efficient teaching-learning strategies. For better e-learning, it is important to develop the vital content of the education and objective measures for detecting nursing errors and adverse events.
Education*
;
Education, Nursing, Continuing
;
Humans
;
Medical Errors
;
Monitoring, Physiologic
;
Nursing*
;
Operating Rooms*
;
Patient Safety
;
Program Development
;
Program Evaluation