1.Bronchogenic carcinoma manifesting unilateral hyperlucent lung: CT features.
Woo Su CHO ; Kyung Soo LEE ; Byoung Ho LEE
Journal of the Korean Radiological Society 1991;27(3):348-350
No abstract available.
Carcinoma, Bronchogenic*
;
Lung, Hyperlucent*
2.Clinical experiences of the lateral and medial upper arm free flap.
Sang Hwan KOO ; Woo Kyung KIM ; Soo shin KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(6):1359-1372
No abstract available.
Arm*
;
Free Tissue Flaps*
3.A Study on the Renal Function in Neonates and Children.
In Soo CHOI ; Young Sook KIM ; Soo Chul CHO ; Jung Soo KIM ; Kyung Woo CHO
Journal of the Korean Pediatric Society 1983;26(8):744-750
No abstract available.
Child*
;
Humans
;
Infant, Newborn*
4.Immunohistochemical and Ultrastructural Studies of Gastric Smooth Muscle Tumor.
Hyang Mi KO ; Kyung Soo KIM ; Jae Hyuk LEE ; Woo Sik JUHNG ; Sang Woo JUHNG
Korean Journal of Pathology 1996;30(3):245-254
To evaluate the differentiation status of smooth muscle in gastric stromal tumors which were negative for S-100 protein, immunohistochemistry using desmin, actin, myosin and vimentin was performed in 14 cases of gastric smooth muscle tumors. Ultrastructural Examination was also performed. For comparison a case of leiomyoma of the esophagus, a case of the sigmoid colon, 10 cases of the uterus were also examined. The results obtained were as follows. All gastric smooth muscle tumors showed vimentin-positivity. Six of 14 gastric smooth muscle tumors, (5 of 8 leiomyoma and 1 of 4 leiomyosarcoma) showed positivity for desmin, actin, and myosin(42.9%). All esophageal, colonic, and uterine leiomyomas showed diffuse positive reaction for desmin, actin, and myosin. Vimentin positivity was also noted in leiomyoma of the colon and uterus. Ultrastructurally, a few cells in the gastric stromal tumors had scattered microfilaments with dense bodies, subplasmalemmal dense plaques, and micropinocytic vesicles. However, most of the tumor cells did not have any of the ultrastructural features of smooth muscle differentiation. Leiomyomas of the esophagus and uterus showed many cytoplasmic microfilaments with dense bodies. These results suggest that most of the benign and malignant tumor cells of gastric stromal tumors have features of the undifferentiated cells, immunohistochemically as well as ultrastructurally, although a few cells have. It is speculated that most gastric stromal tumors may have lost their smooth muscle differentiation.
5.Nephron heterogeneity in response to TMB-S in spontaneouslyhypertensive rats.
Sung Jin KIM ; Kyung Hwan SEUL ; Kyung Woo CHO ; Suhn Hee KIM ; Dong Soo PARK
Journal of Korean Society of Endocrinology 1992;7(3):260-266
No abstract available.
Animals
;
Nephrons*
;
Population Characteristics*
;
Rats*
6.Cyclosporin A in the child minimal change nephrotic syndrome.
Pyung Kil KIM ; Soo Kyung YUN ; Ki Soo PAI ; Ja HOon KOO ; Cheul Woo KOH
Korean Journal of Nephrology 1993;12(4):549-556
No abstract available.
Child*
;
Cyclosporine*
;
Humans
;
Nephrosis, Lipoid*
7.Microsatellite Instability and the Expression of Tumor-associated Genes in Multiple Cancer.
Kyung Soo KIM ; Chan CHOI ; Chang Soo PARK ; Sang Woo JUHNG
Korean Journal of Pathology 1997;31(7):617-627
Genetic changes associated with oncogenes or tumor suppressor genes are frequently observed in human cancers. These changes may be more frequent in multiple primary cancers than sporadic cancers. These experiments were designed in order to know the genetic changes using microsatellite PCR technique and the expression of tumor-associated genes by immunohistochemistry for c-myc and p53 in 17 cases of multiple primary carcinomas. The niicrosatellite instability (MSI) were found in 8 of 17 cases (47.1 %); six cases showed MSI in more than two microsatellite loci and two cases revealed MSI in one locus. MSI was found in 2 out of 7.patients (28.6%) of multiple primary carcinomas arising from the unrelated organs, and 6 out of 10 patients (60.0%) arising from the same or related organs. When each case of multiple primary carcinomas was examined, immunohistochemistry for c-myc was positive in 25 cases (71.4%) and p53 was positive in 21 cases (60.0%) out of 35 cases. But there was no correlation between MSI and expression of tumor-associated genes. From the above the results, MSI is more important in carcinogenesis of multiple primary carcinomas arising from the same or related organs than those from unrelated organs.
Carcinogenesis
;
Genes, Tumor Suppressor
;
Humans
;
Immunohistochemistry
;
Microsatellite Instability*
;
Microsatellite Repeats*
;
Oncogenes
;
Polymerase Chain Reaction
8.Bullous Pemphigoid Responding to DDS.
Kwang Soo KIM ; Ji Soo KIM ; Kyung Jin RHIM ; Sook Ja SON ; Chang Woo LEE
Korean Journal of Dermatology 1982;20(6):913-917
Bullous pemphigoid is a chronic and relatively benign subepidermal blistering disease and is generally considered not to be a sulfa-responsive dermatosis. As a rule, bullous dermatosis that excellently responded to sulfapyridine and sulfones was considered by some to be diagnostic of dermstitis herpetiformia. In 1977, Person and Rogers described 6 cases of bullous pemphigoid responded to sulfapyridine and sulfones. These sulfa-responsive cases were younger than ordinary bullous pemphigoid patients and the histopathologic findings showed prevalence of the neutrophilic infiltration. In this report, the patient who diagnosed as bullous pemphigoid by immunofluorescent studies has younger onset (38 years of age) than usual bullous pemphigoid and histopatbologic findings showed dense neutrophilic infiltrations. The patient was treated with 100-200mg of DDS for 2 months and the skin lesions completely disappeared.
Blister
;
Humans
;
Neutrophils
;
Pemphigoid, Bullous*
;
Prevalence
;
Skin
;
Skin Diseases
;
Sulfapyridine
;
Sulfones
9.THREE DIMENSIONAL FINITE ELEMENT ANALYSIS OF BRANEMARK NOVUM(R)IMMEDIATE IMPLANT PROSTHODONTIC PROTOCOL.
Woo Young KIM ; Yung Soo KIM ; Kyung Soo JANG ; Chang Whe KIM
The Journal of Korean Academy of Prosthodontics 2001;39(5):463-476
Since the treatment of edentulous patients with osseointegrated implant was first introduced more than 30 years ago, implant therapy has become one of the most important dental treatment modalities today. Based on the previous experience and knowledge. Branemark Novum(R) protocol was introduced with the concept of simplifying surgical and prosthetic technique and reducing healing time recently. This protocol recommends the installation of three 5mm wide diameter fixtures in anterior mandible and the prefabricated titanium bars for superstructure fabrication. This study was designed to analyze the stress distribution at fixture and superstructure area according to changes of fixture number, diameter and superstructure materials. Four 3-dimensional finite element models were fabricated. Model 1 - 5 standard fixtures (13mm long and 3.75mm in diameter) & superstructure consisted of type IV gold alloy and resin Model 2 - 3 wide diameter fixtures (13mm long and 5.0mm in diameter) )& superstructure consisted of type IV gold alloy and resin Model 3 - 3 wide diameter fixtures (13mm long and 5.0mm in diameter) )& superstructure consisted of titanium and resin Model 4 - 3 wide diameter fixtures (13mm long and 5.0mm in diameter)& superstructure consisted of titanium and porcelain A 150N occlusal force was applied on the 1st molar of each model in 3 directions-vertical(90degree)horizontal(0degree)and oblique (120degree). After analyzing the stress and displacements, following results were obtained. 1. There were no significant difference in stress distribution among experimental models. 2. Model 2,3,4 showed less amount of compressive stress than that of model 1. However, tensile stress was similar. 3. Veneer material with a high modulus of elasticity demonstrated less stress accumulation in the superstructure. Within the limits of this study.Branemark Novum(R) protocol demonstrated comparable biomechanical properties to conventional protocol.
Alloys
;
Bite Force
;
Dental Porcelain
;
Elastic Modulus
;
Finite Element Analysis*
;
Humans
;
Mandible
;
Models, Theoretical
;
Molar
;
Prosthodontics*
;
Titanium
10.Cytomegalovirus Infection In a Patient with Hypersensitivity Angiitis due to H-S Purpura: A case report.
Ji Shin LEE ; Hyang Mi KO ; Kyung Soo KIM ; Chang Soo PARK ; J Sang Woo UHNG
Korean Journal of Pathology 1995;29(1):119-121
Gastrointestinal cytomegalovirus(CMV) infection in adults is observed as a part of a generalized or localized infection in patients who are immunocompromized. We report a case of CMV infection of the small intestine. The patient is a 34 year-old woman who has complained of palpable purpura in the lower extremities and buttocks, and arthralgia of large joints. The skin biopsy showed fibrinoid necrosis and neutrophils with leukocytoclasis, which findings are compatible with hypersensitivity angiitis. The patient received steroid and cyclophosphamide. During the follow-up period, generalized edema and bloody stool were detected. Resected specimen of small bowel has multiple aphthous ulcer. Microscopically, cytomegalic cells are observed along the endothelial cells and mesenchymal cells. In situ hybridization using DNA probes against CMV revealed positive staining in the cytomegalic inclusions in vascular endothelial and mesenchymal cells.
Adult
;
Male
;
Female
;
Humans
;
Biopsy