No abstract available.
Humans ; Infant* ; Parturition*

No abstract available.
Cleft Lip* ; Diagnosis* ; Ultrasonography*

Carcinoma of the breast can produce cutaneous metastases which sbow highly diversified clinical pictures. The cutaneous metastases produce four definite clinical types: inflammatory carcinoma, telangiectatic carcinoma, nodular carcinoma, and carcinoma, en cuirasse. We present a case of 78-year-old nulliparous woman who had several painful dark purplish colored zosteriform papulovesicular eruptions, suggestive of herpes zoster, on the right breast, right axilla, scapular area, and upper arm for three month. Two month later, well dermacated linearly arranged erysipeloid eruptions appeared around the previous skin lesions and the right chest wall. Histopathological findings showed metastatic ductal carcinoma with massive vascular permeation but the primary focus was undetermined.
Female ; Humans ; Neoplasm Metastasis

One of the important anesthetic problems is cross-infection in anesthetic machines in operating rooms. This study is an attempt to determine the transfer of organisms through anesthetic apparatus. The bacteriological experiments were based on selective culture with blood agar media(Difco, U.S.A.) in the operating theater, recovery room and in anesthetic apparatus which was either sterilized with chemicals or without sterilization. Furthermore, nasopharyngeal culture also determined in normal healthy patients. The hypersensitivity test was performed by Kolmer's method. The results are as follows; 1) Most of the organisms in the operating room were Staphylococcus and Baeillus subtilis, (table 1.) 2) Bacteriological examination of unsterilized anesthetic acessories showed Staphylococcus, Streptococcus and Gram negative bacillus. (table 2) The sterilizaiton of anesthetic apparatus with Benzalkonium chloride solution for 40 minutes was superior to that with our standard Sterilized solution for one and half hours. (table 3.) 3) The majority of colonies responded to Albamycine, Erythromycine, Kanamycine and Achromycine. (table4, 4-a.) 4) Strep.nonhemolyticus (37.0%) was the most common bacterial flora of the nasopharynx isolated from healthy persons. (table 5.) In conclusion, it is most important to check the bacteriological examination of operating roon s and anesthetic apparatus at regular intervals and to clean hands before and after anesthesia.
Agar ; Anesthesia ; Bacillus ; Benzalkonium Compounds ; Erythromycin ; Hand ; Humans ; Hypersensitivity ; Kanamycin ; Nasopharynx ; Operating Rooms ; Recovery Room ; Staphylococcus ; Sterilization ; Streptococcus ; Tetracycline

The ambulatory electrocardiographic examinations were performed in 31 patients (mean age of 59.4+/-9.3 yrs : male 16 cases, female 15 cases) with ischemic heart disease to evaluate the clinical features of ST segment more than 1 mm persisting for 45 seconds or longer. The incidence of associated disease are angina pectoris 14 cases, acute myocardial infarction 3 cases, old myocardial infarction 7 cases, hypertension 19 cases, diabetes mellitus 5 cases, cerebrovascular disease 4 cases, aortic regurgitation 2 cases, ventricular arrhythmia 1 case and chronic renal faliure 1 case. 93.7% of 252 monitored episodes of transient myocardial ischemia were silent. The incidence and duration of transient myocardial ischemia were 8.1+/-6.7 episodes/day (7.6+/-6.5episodes/day for silent myocardial ischemia, 0.5+/-0.9 episodes/day for silent ischemia, 7.6+/-14.1mins/day for symptomatic ischemia). The heart rate at the onset of ST segment depression is higher in symptomatic episode than silent episode (94.6+/-19.7 vs 82.1+/-17.4/min,. p<0.05). But duration of ST segment depression is longer in silent episode than symptomatic episode(32.4+/-97.7 vs 14.8+/-10.2/min,. p<0.01). Maximal ST segment depression was similar between silent and symptomatic episode (1.61+/-0.65 mm, 1.97+/-0.84 mm, repectively). 55.5% of silent episodes occurred during sleep or resting state and 60% of symptomatic episodes occurred during strenuous effort, exercise or eating (p<0.01). Transient myocardial ischemia developed not more frequently in the morning probably because the 24 hour Holter electrocadiographic examination was performed during hospitalization in the majority of cases.
Angina Pectoris ; Aortic Valve Insufficiency ; Arrhythmias, Cardiac ; Depression ; Diabetes Mellitus ; Eating ; Electrocardiography ; Female ; Heart Rate ; Hospitalization ; Humans ; Hypertension ; Incidence ; Ischemia ; Male ; Myocardial Infarction ; Myocardial Ischemia*

No abstract available.
Seizures* ; Sparganosis*

No abstract available.
Acne Vulgaris*

Extramammary Paget's disease (EMPD) is an intraepithelial neoplastic disorder which is included as a rare malignant condition. However, it sometimes shows aggressive behavior of local recurrence and coexisting malignancy. We had experienced nine cases of EMPD involving the scrotum for seven years. Two cases of them presented metastasis. The first case presented extensive inguinal lymph node metastasis with underlying adnexal adenocarcinoma one year after wide local excision. The second case initially presented multiple metastasis to the liver and in the lymph node. The latter, showing fulminant progression with liver metastasis, may be only the second case reported in English literature. EMPD is considered as a malignant neoplasm with aggressive behavior from initial presentation. Because wide local excision of the lesion alone may be occasionally insufficient, a careful follow-up must be done to detect recurrence or internal malignancy.
Aged ; Case Report ; Fatal Outcome ; Female ; Human ; Liver Neoplasms/secondary* ; Magnetic Resonance Imaging ; Male ; Paget's Disease, Extramammary/surgery ; Paget's Disease, Extramammary/pathology* ; Testicular Neoplasms/surgery ; Testicular Neoplasms/pathology*

No abstract available.
Breast Neoplasms* ; Breast* ; Drug Therapy*

We have studied the patterns of P-glycoprotein expression before and after 3 cycles of induction chemotherapy (5-fluorouracil, adriamycin and cyclophosphamide) using immunohistochemically stained paraffin-embedded specimen of 28 patients with locally advanced breast cancer. The frequency of P-glycoprotein expression in untreated breast cancer turned out to be very low: only one out of 28 untreated, biopsy specimen at the time of diagnosis was positive. The frequency of P-glycoprotein expression was markedly increased from 9.1% before chemotherapy to 63.6% after induction chemotherapy (p = 0.006). After 3 cycles of induction chemotherapy, 25 patients had obtained clinical response to chemotherapy (4, CR; 21, PR). Eleven out of 25 tumors (44%) showing clinical response and all three tumors (100%) with minimal response have expressed P-glycoprotein. One out of 6 patients (16.7%) with microscopic residual tumor seen in mastectomy specimen expressed P-glycoprotein, whereas 13 of 22 patients (59.1%) with gross residual tumor showed the presence of P-glycoprotein (p = 0.08). The frequency of intrinsic P-glycoprotein expression in untreated breast cancer was quite low, but approximately half of the patients do acquire P-glycoprotein expression during the cycles of induction chemotherapy. Therefore, the results suggest that the immunohistochemical detection of P-glycoprotein on residual tumor cells after induction chemotherapy can predict acquired drug resistance in breast cancer.
Adult ; Aged ; Breast Neoplasms/chemistry/*drug therapy/pathology ; Breast Neoplasms/chemistry/*drug therapy/pathology ; Drug Resistance ; Drug Resistance ; Female ; Human ; Immunohistochemistry ; Membrane Glycoproteins/*analysis ; Middle Age ; P-Glycoprotein