No abstract available.
Gentamicins* ; Humans ; Infant, Newborn*

BACKGROUND: Nevus depigmentosus was first reported in 1884 by Lesser. It is defined as a congenital non-progressive hypopigmented macule or patch that is stable in its relative size and distribution throughout the life of the individual. The etiopathogenesis and histopathological characteristics of nevus depigmentosus are not fully established. OBJECT: The purpose of this study is to investigate the clinical and histopathological characteristics and pathogenesis of nevus depigmentosus. METHODS: Clinieal survey was carried out on forty-nine patients with nevus depigmentosus and two skin biopsies were taken from eighteen patients; from the central part of the depigmented lesion and the border of the lesion including the perilesional normal skin. The sections were stained with hematoxylin-eosin, Fontana-Masson and S-100 protein. The ultrastructural evaluation were also done to detect alternation of melanocytes. RESULTS: The results are as follows ; 1. The lesions were mostly (91.8%) present before the age of three, but some lesions appeared in childhood (8.2%). 2. The lesions were most frequently found on the trunk (42.9%), followed by the face and scalp (20.4%). 3. There were 33 patients (67.3%) with the isolated type, 15 patients (30.6%) with the dermatomal type and one patient with the whorled type. 4. Histopathological studies have shown that the stainability of Fontana-Masson in the lesions of nevus depigmentosus was decreased compared with perilesional nomal skin, but there were no changes in the number of melanocytes. 5. There was a great reduction in the number of melanosomes in melanocytes and keratinocytes of nevus depigmentosus. In keratinocytes, there was some aggregations of melanosomes and some of them showed membrane bound architecture. CONCLUSION: The results of this study support the fact that nevus depigmentosus is caused by functional defects of melanocytes and morphological abnonnalities of melanosomes.
Biopsy ; Humans ; Keratinocytes ; Melanocytes ; Melanosomes ; Membranes ; Nevus* ; S100 Proteins ; Scalp ; Skin

A total of 162 patients with invasive cervical cancer was investigated retrospectively with a view to elucidate the efficacy of pretreatment staging procedures of application with intravenous pyelography, cystoscopy, rectosigmoidoscopy. All 72 intravenous pyelograms, 155 sigmoidoscopies, 158 cystoscopies were normal. Of 111 patients with stage Ib who had paraaortic lymph node biopsies, two patients had a positive node(0.02%). Of 51 patients with stage II who had paraaortic lymph node biopsies, five patients had positive paraaortic lymph node(10%). And the accuracy of computed tomography and magnetic resonance imaging in the evaluation of invasive cervical cancer was assessed. In evaluating stage of cervical cancer, clinical staging had an accuracy of 78.9%, compared with 65.7% for CT and 58.9% for MRI. And for detection of parametrial invasion, clincal staging had an accuracy of 85.9%, compared with 85.1% for CT and 78.9% for MRI. Both modalities were comparable in evaluating lymph node metastasis ( 76.1% for CT, 74.4% for MRI ). IVP, cystoscopy and sigmoidoscopy for staging procedure evaluated in this study are unnecessary and should no longer be performed in patients with early stage cervical cancer. In addition, paraaortic lymph node biopsies in the absence of clinically suspicious nodes are not warranted. Compared with CT and MRI, pelvic examination offered improved evaluation of cervical cancer staging, parametrial invasion, but CT and MRI was useful in detecting the pelvic lymph node metastasis which was nearly impossible by clinical evaluation.
Biopsy ; Cystoscopy ; Gynecological Examination ; Humans ; Lymph Nodes ; Magnetic Resonance Imaging* ; Neoplasm Metastasis ; Retrospective Studies ; Sigmoidoscopy ; Urography ; Uterine Cervical Neoplasms

No abstract available.
Nerve Regeneration*

No abstract available.
Infusions, Intraosseous* ; Resuscitation* ; Shock, Hemorrhagic*

Treatment of zygoma fracture with displacement at the multiple ariticulations frequently results in incomplete fracture reduction because of difficulties involved in the application of vector force during the reduction procedure. The vector force in opposite to the vector force of injury may not exert adequately through the skin incisions of open reduction. We treated 46 patients of isolated zygoma fracture with transcutaneous screw pin reduction and external fixation. After insertion of a transcutaneous screw pin through the fractured zygoma segment, the vector force of reduction could be applied easily by tracting screw pin along with the opposite force to the injury vector. The external fixation could easily immobilize the fracture segment for a period from 9 to I4 days. In all patients accept one, we could perform fracture reduction accurately without malunion or any other complication. Aside from the direct application of vector froce in the desired direction, advantages of this method are shorter operation time, no incision scar, and no implantation of internal fixation.
Cicatrix ; Humans ; Skin ; Zygoma*

No abstract available.
Emergencies* ; Humans

Woolf syndrome is characterized by piebaldism and congenital deafness. Facial features of Waardenburg syndrome are absent and the parents and siblings are unaffected. We report herein a case of Woolf syndrome in 21-year-old male patient who has deafness of the righr ear and hypopigmented patches of whole body since birth. This pigmentary disorder may associate with other systemic abnormalities, we suggest this syndrome belongs to the spectrum of developmental abnormalities.
Deafness* ; Ear ; Humans ; Male ; Parents ; Parturition ; Piebaldism* ; Siblings ; Waardenburg Syndrome ; Young Adult

Woolf syndrome is characterized by piebaldism and congenital deafness. Facial features of Waardenburg syndrome are absent and the parents and siblings are unaffected. We report herein a case of Woolf syndrome in 21-year-old male patient who has deafness of the righr ear and hypopigmented patches of whole body since birth. This pigmentary disorder may associate with other systemic abnormalities, we suggest this syndrome belongs to the spectrum of developmental abnormalities.
Deafness* ; Ear ; Humans ; Male ; Parents ; Parturition ; Piebaldism* ; Siblings ; Waardenburg Syndrome ; Young Adult

No abstract available.
Acute Kidney Injury* ; Prospective Studies*