1.Surgical approach of orbital medial wall fractures.
Hee Moon LEE ; Kyung Mok KIM ; Young Seob LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(6):1075-1083
Medial orbital wall fracture was described by Converse and Smith in the first time in 1957. These fractures which comprise more than 30% of all the orbital wall fracture are may easily be overlooked in routine orbital radiology. Accordingly, examination with orbital CT is essential for accurate diagnosis and appropriate treatment. These type of fracture are followed frequently by post-oprative complication such as diplopia and enophthalmos because it is very difficult to approach to orbital medial was in these operations. The mechanism of the orbital wall fractures are abruptly increased hydraulic pressure by sudden impact on orbital rim or soft tissue of orbital region. So patients who show the signs of subcutaneous emphysema, edema on the orbital region or diplopia need to get through examination with orbital CT for accurate diagnosis and immediate reconstruction of the fractured orbital wall. Conventional approaches in the operations of the orbital medial wall fractures are that with bicoronal incision, subciliary incision, transconjunctival incision and infra-orbital rim incision. But, approach with bicoronary incision, needs broader dissection and longer time for operation. Operations with transconjunctival incision and that with subciliary incision have difficulty to approach to fractured sites. Operations with other conventional methods may be also followed by scar problem. The authors performed reduction and reconstruction of the fractured orbital medial wall fractures successfully without any complications and difficulties by intra-eyebrow approach with which they made incision of 2 - 2.5 cm on mid-area of eyebrow to expose fractured medial wall with good operative field.
Cicatrix
;
Diagnosis
;
Diplopia
;
Edema
;
Enophthalmos
;
Eyebrows
;
Humans
;
Orbit*
;
Subcutaneous Emphysema
2.CALLUS DISTRACTION TECHNIQUE FOR TRAUMATIC ARTICULAR METACARPOPHALANGEAL DEFECTS.
Seung Goog HWANG ; Young Seob LEE ; Kyung Mok KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1110-1115
No abstract available.
Bony Callus*
4.A case of VATER syndrome.
Seong Jin HA ; Ki Hyun CHUNG ; Oh Kyung LEE ; Wan Seob KIM ; Kyung Hye LEE
Journal of the Korean Pediatric Society 1993;36(4):583-588
The VATER syndrome is a group of congenital anomalies with a nonrandom tendency for concurrence. Defects include vertebral, anorectal malformation, tracheoesophageal fisutla with esophageal atresia, radial-limb, vascular, and renal abnormalities. The critical period of organogenesis is at or before the sixth or seventh week of gestation. We experienced one case of VATER syndrome in a 1 day old male neonate having vertebral anomalies, esophageal atresia with tracheoesophageal fistula to the distal esophageal segment, imperforated anus, left renal dysplasia with hydronephrosis of the right kidney and both hydroureter, patent ductus arteriosus. We report a case of VATER syndrome with brief review of related literature.
Anal Canal
;
Critical Period (Psychology)
;
Ductus Arteriosus, Patent
;
Esophageal Atresia
;
Humans
;
Hydronephrosis
;
Infant, Newborn
;
Kidney
;
Male
;
Organogenesis
;
Pregnancy
;
Tracheoesophageal Fistula
5.Anaerobic bacteria isolated from the clinical specimens during the period of 1983 to 1992.
Ahn Na LEE ; Young Sook KANG ; Kyung Won LEE ; Yoon Seob JUNG ; Kyung Soon SONG
Korean Journal of Infectious Diseases 1993;25(1):9-17
No abstract available.
Bacteria, Anaerobic*
7.Clinical Bacteriologic Study of Serratia Marcescens Septicemia.
Hyo Sook HONG ; Wan Seob KIM ; Oh Kyung LEE ; Myung Ho LEE
Journal of the Korean Pediatric Society 1987;30(12):1409-1418
No abstract available.
Sepsis*
;
Serratia marcescens*
;
Serratia*
8.A case of Hutchinson Gilford Progeria Syndrome.
Myung Ho CHO ; Yong Woo CHOI ; Wan Seob KIM ; Oh Kyung LEE ; Myung Ho LEE
Journal of the Korean Pediatric Society 1986;29(5):106-110
No abstract available.
Progeria*
9.Prognostic Significance of the Tall Cell Variant of Papillary Thyroid Carcinoma: Expression of p53, bcl-2 & Leu-M1 proteins.
Won Mi LEE ; Joo Seob KEUM ; Eun Kyung HONG ; Moon Hyang PARK ; Jung Dal LEE
Korean Journal of Pathology 1998;32(11):1000-1007
Papillary carcinoma of the thyroid is a well differentiated neoplasm and usually has a good prognosis. However, a subset of morphologically distinct papillary carcinoma has bad prognoses. The tall cell variant of papillary carcinoma (TCPC), characterized by tall columnar cells with a height at least twice the width, is the one of these. In order to differentiate TCPC from usual papillary carcinoma (UPC) in terms of prognosis, we performed immunohistochemical studies for the expression of p53, bcl-2 and Leu-M1 proteins in 25 cases of TCPC, 26 cases of UPC and 14 cases of poorly differentiated, solid type papillary carcinoma (SPC) with an analysis of clinical parameters. The nuclear expression of p53 was noted in one case each of UPC and TCPC. The cytoplasmic p53 expression of TCPC, UPC, and SPC was observed in 17/25 cases (68%), 14/26 cases (54%), 3/14 cases (21%), respectively. bcl-2 expression was 19/25 cases (76%), 18/26 cases (69%), 5/14 cases (36%), and that of Leu-M1 was 21/25 cases (84%), 18/26 cases (69%), 4/14 cases(29%), respectively. There were no statistical significance in the expression of those immunoproteins among these three groups (p>0.05). The p53 protein was consistently expressed in the cytoplasm rather than nucleus in this study and was very well correlated to bcl-2 positivity (p<0.01). There were no statistical significance in any clinical parameters examined among these three groups (p>0.05). In conclusion, TCPC can not be separated from UPC as a distinct entity in this study and the cytoplasmic expression of p53 protein provides another mechanism of p53 inactivation in tumorigenesis of the thyroid papillary carcinoma, possibly by bcl-2 related mechanism.
Carcinogenesis
;
Carcinoma, Papillary
;
Cytoplasm
;
Immunoproteins
;
Prognosis
;
Thyroid Gland*
;
Thyroid Neoplasms*
10.M-VAC Combination Chemotherapy in Advanced Bladder Cancer.
Kyung Seob LEE ; Chun Il KIM ; Sung Choon LEE
Korean Journal of Urology 1987;28(1):74-78
Patients with advanced carcinoma of the bladder that relapses or persists after conventional therapy have a poor prognosis. The management of the patient with recurrent local or disseminated bladder cancer presents a difficult clinical problem. In l985, Sternberg et al reported 7l% significant tumor regression and 50% complete clinical remission with M-VAC(Methotrexate, Vinblastin, Adriamycin and Cisplatin) combination chemotherapy for treatment of advanced bladder carcinoma Herein, we report 4 cases of M-VAC combination chemotherapy in far advanced bladder carcinoma with had measurable metastatic lesions enough to evaluate the objective response of chemotherapy.
Doxorubicin
;
Drug Therapy
;
Drug Therapy, Combination*
;
Humans
;
Prognosis
;
Recurrence
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*