We report a case of bacteriologically proven salmonella infection on the thoracic vertebra in a patient with previous history of pulmonary tuberculosis, in the non-endemic area with no history of sickle cell disease and typhoid fever. A forty-three years old female patient was admitted because of severe back pain, chest pain, lower extremity weakness and intermittent high fever elevation. On plain X-ray there was narrowing of T11-12 disc space with adjacent vertebral body destruction localized centrally around the disc and paravertebral abscess. She had an old history of pulmonary tuberculosis and treated with antituberculosis medication twenty years ago. We treated this patient by abscess drainage, anterior curettage and iliac corticocancellous strut bone graft over the T11 to T12 by anterior transthoracic approach. Histopathological diagnosis was chronic vertebral osteomyelitis with chronic inflammatory reaction. Pus culture reported to have grown salmonella typhi group D, sensitive to ampicillin, chloramphenicol, gentamicin and tetracycline. We could establish the diagnosis and effectively treat the disease with early surgical intervention.
Abscess ; Ampicillin ; Anemia, Sickle Cell ; Back Pain ; Chest Pain ; Chloramphenicol ; Curettage ; Diagnosis ; Drainage ; Female ; Fever ; Gentamicins ; Humans ; Lower Extremity ; Osteomyelitis ; Salmonella Infections ; Salmonella typhi ; Salmonella* ; Spine* ; Spondylitis* ; Suppuration ; Tetracycline ; Transplants ; Tuberculosis, Pulmonary ; Typhoid Fever

PURPOSE: To evaluate the degree of injury of the spinal cord in relation with the space available for the spinal cord at the level of injury, the sagittal diameter of the spinal canal at the uninjured levels, and the Pavlov ratio at the uninjured levels in fractures and dislocations of the lower cervical spine. MATERIALS AND METHODS: We retrospectively reviewed the records and radiographs of patients who had sustained an acute fracture or dislocation of the cervical spine from 1990 to 1995. We collected patients from Orthopedic and Neurosurgical department of Chonbuk University Hospital and at Orthopedic department of Presbyterian Medical Center. Of the 69 patients analyzed, twelve had no neurological deficit, eleven had an isolated nerve-root injury, twenty-two had an incomplete injury of the spinal cord, and twenty-four had a complete injury. We measured above three parameters from the plain lateral radiographs and assessed the difference by one-way ANOVA and unpaired t-test. RESULTS: 1. The mean space available for the spinal cord at the level of injury was 12.9 millimeter for the complete injury of the spinal cord,13.8 millimeter for the incomplete injury, 14.7 millimeter for an isolated nerve-root injury, and 15.7 millimeter for no neurological deficit group. The overall difference among the groups was significant (F=6.98, P=0.0004). The patients who had a complete injury of the spinal cord and those who had an incomplete injury of the spinal cord were significantly different from the patients who had an isolated nerve-root injury and those who had no neurologic deficit (P=0.002). 2. The mean sagittal diameter of the canal at the proximal and distal uninjured level was 14.3 and 14.6 millimeter for the complete injury of the spinal cord, 14.9 and 14.9 millimeter for the incomplete injury, 15.5 and 16.6 millimeter for an isolated nerve-root injury, and 16.9 and 16.5 millimeter for no neurological deficit group. The patients who had a complete injury of the spinal cord and those who had an incomplete injury of the spinal cord were significantly different from the patients who had an isolated nerve-root injury and those who had no neurologic deficit (P=0.001). 3. The mean Pavlov ratio at the proximal and distal uninjured level was 0.90 and 0.86 for no neurologic deficit group, 0.85 and 0.87 for an isolated nerve-root injury, 0.76 and 0.75 for the incomplete injury of the spinal cord, and 0.76 and 0.76 for the complete injury. The patients who had a complete injury of the spinal cord and those who had an incomplete injury of the spinal cord were significantly different from the patients who had an isolated nerve-root injury and those who had no neurologic deficit (P=0.001). CONCLUSIONS: The patients who sustained a permanent injury of the cord usually had had a narrower sagittal diameter (<14mm) and a lower Pavlov ratio (<0.80) of the spinal canal before injury. Patients who had a large sagittal diameter of the canal may be more likely to be spared a permanent injury of the spinal cord following a fracture or dislocation of the cervical spine compared with patients who have a narrow canal. These findings demonstrated that the severity of the injury of the spinal cord was in part associated with the space available for the cord (at risk:<13mm) after the injury, as measured on plain lateral radiographs.
Dislocations* ; Humans ; Jeollabuk-do ; Neurologic Manifestations ; Orthopedics ; Protestantism ; Retrospective Studies ; Spinal Canal ; Spinal Cord* ; Spine*

Tailgut cyst is a rare congenital anomaly arising in the retrorectal space. Malignancy arising from the tailgut cyst is very rare. We experienced a case of adenocarcinoma arising from the tailgut cyst. The findings of this rare tumor are bony destruction of the sacrum on plain radiograph, a cystic mass on ultrasound, a low attenuation mass with calcification and enhancement on CT, and a multiseptated cystic mass containing solid component on MRI.
Adenocarcinoma* ; Magnetic Resonance Imaging ; Sacrum ; Ultrasonography

Displaced acetabular fractures have given rise to difficulty to the management, It has been unique diagnostic and operative challanges for the surgeon. We made a retrospective study of hip arthroplasty in fourteen patients who had a history of previous acetabular fracture. The most of patients was sutfered from traumatic osteoarthritis, We performed two bipolar hemiarthroplasty, eleven non-cement cup and one case Charnley cup replacement were done. The purpose of this stady was to determine the outcome long-term cup. The clinical results showed that pain was most improved at foliow-up, but the incidence of radiographic loosening and revisions were higher 42.8% within 10 years. We conclude that a history of prior acetahular fracture has a significant adverse impact on the long term out come of acetabular cup in total hip arthroplasty.
Acetabulum* ; Arthroplasty ; Arthroplasty, Replacement, Hip* ; Hemiarthroplasty ; Hip ; Humans ; Incidence ; Osteoarthritis ; Retrospective Studies

No abstract available.
Diaphragmatic Eventration*

OBJECTIVE: This study was carried out to evaluate the effect of the isolation methods of inner cell mass from mouse blastocyst, types of feeder cells and treatment time of mitomycin C on the formation rate of ICM colony. METHODS: The inner cells were isolated by conventional immunosurgery, partial trophoblast dissection with syringe needles and whole blastocyst co-culture method. Commercially available STO and primary cultured mouse embryonic fibroblast (pMEF) feeder cells were used, and mitomycin C was treated for 1, 2 or 3 hours, respectively. The formation rate of ICM colony was observed after isolation of ICM and culture of ICM on the feeder cells for 7 days. RESULT: The ICM colony formation rate on STO were significantly higher in partial trophoblast dissection group (58%) than that in immunosurgery (12%) or whole blastocyst culture (16%) group (p<0.05). The formation rate on pMEF feeder layer was higher in partial trophoblast dissection (88%) and whole blastocyst culture (82%) group than that in immunosurgery (16%) group (p<0.05). When mitomycin C treated to pMEF for 2 hours, the formation rate of 88% was significantly higher than those of other conditions. CONCLUSIONS: Above results showed that the efficient isolation method of ICM from blastocyst was the partial trophoblast dissection and the appropriate treatment time of mitomycin C was 2 hours. However, the subculture of ICM colony and characterization of stem cells should be carried out to confirm the efficacy of the partial trophoblast dissection method.
Animals ; Blastocyst ; Coculture Techniques ; Feeder Cells* ; Fibroblasts ; Mice* ; Mitomycin* ; Needles ; Stem Cells ; Syringes ; Trophoblasts

No abstract available.
Humans

The paramount importance of breast feeding for the health of the infants has been recognized by untritionists and physicians. Although many advantages of the breast feedng, exclusive breast feeding without weaning diet or supplement food during prolonged perind in infants may produce iron deficiencyh anemia. This study was conducted to find out the hematologic state in exclusively prolonged breast-fed infants among these anemic patients and the way of thinking about their baby's feeding method in their mothers. Mothers of the anemic patients has been surveyed with questionare. The results and problems obtained from this study are summerized as follows. 1) Among 40 patients of this study, 27 were male (67.5%) and 13 were female (32.5%). Mean age was 12.6+/-2.7 month and 9 & 11 month of age were the most common, respectively (15.0%). 2) Mean age of mothers was 29.5 year. The 25 34 year-old group was most common. 3) Education levels of mothers were primary 10%, middle 10%, high 60%, and college graduate 20%. 4) In motivatins of breast feeding. Persuasion of husband or the parent of husband' 19(47.5%). 'Convenience for use' 12 (30.0%), and 'Through mass media or public information' 9 (22.5%). 5) In the causes of prolonged breast feeding, 'Think that satisfactory nutrition for baby is possible with breast milk alone' 4(10.0%), 'Due to persuasion of husband or the parents of husband' 11 (27.5%), 'Baby did no suck milk bottle or eat other diet except breast milk' 25 (62.5%). 6) In whether or not acknowledgment of the necessity of weaning diet, 'Know it but not consider so important 22 (55.0)%, 'Do not know at all) 15 (37.5%), and 'Breast milk, that will do' 3(7.5%). 7) Hb level in patient group, from 6 to 6.9g/dl was 2 (50.0%), from 7 to 7.9g/dl was 3 (7.5%), from 8 to 8.9%g/dl was 15 (37.5%), and from 9 to 10 g/dl was 20 (50.0%). From 9 to 10g/dl was the most common. Hematologic findings were Hb 8.8+/-0.9g/dl, Hct 28.8+/-3.0%, MCV 64.7+/-6.7 fl, MCH 20.0+/-2.5pg, MCHC 30.8+/-1.5g/dl. Platelet 452.5+/-142.9x103/mm3, Reticulocyte count 1.4+/-0.6%, Fe 28.6+/-14.1 g/dl, TIBC 446.7+/-66.2 g/dl, Ferritin 10.5+/-7.0ng/ml. Transferrin saturation 6.6+/-3.5%. 8) In association with duration of breast milk feeding and hematologic findings, as duration was prolonged, Hb, Hct, MCV & MCH were significantly decreased (p<0.01).
Adult ; Anemia* ; Blood Platelets ; Breast Feeding* ; Breast* ; Diet* ; Education ; Feeding Methods ; Female ; Ferritins ; Humans ; Infant ; Iron ; Male ; Mass Media ; Milk ; Milk, Human ; Mothers ; Parents ; Persuasive Communication ; Reticulocyte Count ; Spouses ; Thinking ; Transferrin ; Weaning*

No abstract available.
Thyroglobulin* ; Thyroid Gland*

No abstract available.
Sinusitis*