No abstract available.
Nephrolithiasis* ; Uric Acid*

Glomus tumor arises from the subcutaneous glomus body, which is an arteriovenous anastomosis involved in the regulation of cutaneous blood circulation and are widely distributed in the body, especially the hand. Twelve patients (male 3, female 9) with glomus tumors of the hand, who were operated from Jan. 1986 to Dec. 1994 were selected. The lesions were distributed in the distal phalanges of the thumb (6 cases), the index (3 cases), the ring finger (2 cases) and the little finger (1 case). All patients had the classic triad of symtoms: pain, tenderness and temperature sensitivity. Palpable mass (4 cases) and bluish purple discoloration in the skin (6 cases) were also presented. They had no trauma history and on the roentgenography, bone change detected in 2 cases. A simple excision with partial nail extraction was done in all cases. The symtoms were disappeared in all cases and no recurrence was found. For a complete cure, meticulous complete excision is the only recommended treatment.
Arteriovenous Anastomosis ; Blood Circulation ; Female ; Fingers ; Glomus Tumor* ; Hand* ; Humans ; Radiography ; Recurrence ; Skin ; Thumb

No abstract available.
Child* ; Humans ; Mycobacterium bovis* ; Skin* ; Tuberculin Test* ; Tuberculin*

SUMMARY: The present study was carried out to evaluate whether the coculture system of human embryos with Vero cells can improve the quality of embryo or overcome the repetitive implantation failures in order to obtain pregnancy. From January to December 1996, a total 202 cases which patients with the problems of repetitive implantation failures (group I) or those with the poor embryonic quality in their previous cycles (group II) was analysed. The quality of cocultured embryo, pregnancy, on-going and implantation rates between coculture and control groups were compared. Of 93 cases in group I, coculture was performed in 34 cases and conventional IVF for the rest. Of 109 cases in group II, 36 for coculture and 73 for conventional IVF. In group I, pregnancy, on-going and implantation rates in coculture group (14/34 (41.2%), 9/34 (26.5%), 16/81 (19.8%), respectively) were higher than those of control (11/59 (18.6%), 8/59 (13.6%), 12/152 (7.9%), respectively). There is significance in the pregnancy and implantation rates (p=0.028 and p=0.015). In group II, pregnancy, on-going and implantation rates in coculture group (8/36 (22.2%), 5/36 (13.9%), 8/87 (9.2%), respectively) were higher than those of control (5/73 (6.8%), 3/73 (4.1%), 3/158 (1.9%), respectively). Like the result of group 1, there is significance in the pregnancy and implantation rates (p=0.028 and p=0.022). Coculture system with Vero cells works well in the groups of the two indications. Although the case of 3 day-coculture was small as 15 cases in group II, 3 day-coculture improved pregnancy rate (4/15 (26.7%)). Therefore, 3 day-coculture with assisted hatching is recommended to the patients with poor embryonic quality. In conclusion, coculture system with Vero cells can be suggested as an effective method which improves pregnancy rate in those who have repetitive implantation failures or whose embryonic quality was poor in their previous cycles.
Coculture Techniques* ; Embryonic Structures ; Humans ; Humans* ; Pregnancy ; Pregnancy Rate ; Prognosis* ; Vero Cells

No abstract available.
Abortion, Habitual* ; Female ; Immunization* ; Lymphocytes* ; Pregnancy

Mannitol is an osmotic diuretic agent useful in a variety of clinical conditions. This study is based on acid-base and electrolyte changes seen after the intravenous infusion of hypertonic mannitol for the prevention of cerebral edema. The study subjects were divided into 3 groups: for group A, an amount of 300-900 mL 15% mannitol was intravenously infused over the period of 60 to 90 minutes; for group B, 1,200-2,600 mL over 12 to 24 hours; and for group C, 3,200-4,900 mL over more than 24 hours. In group A, blood pH is increased from 7.43+/-0.07 to 7.46+/-0.04, and plasma HCO3- from 25.3+/-2.1 to 28.9+/-2.9 mEq/L, but plasma K+ is decreased from 4.3+/-0.6 to 3.7+/-0.8 mEq/L. In group B, blood pH is increased from 7.42+/-0.02 to 7.47+/-0.06, and plasma HCO3- from 25.2+/-1.8 to 29.1+/-2.9 mEq/L, but plasma K+ is decreased from 4.2+/-0.3 to 3.8+/-0.5 mEq/L. In group C, blood pH is increased from 7.41+/-0.01 to 7.52+/-0.04, and plasma HCO3- from 24.9+/-1.2 to 27.7+/-2.5 mEq/L, but plasma K+ is decreased from 4.2+/-0.1 to 3.9+/-0.2 mEq/L. These results showed that intravenous infusion of mannitol could induce metabolic alkalosis and hypokalemia, regardless of its dose. The mannitol induced metabolic alkalosis may be due to increased renal HCO3- production.
Alkalosis* ; Brain Edema ; Hydrogen-Ion Concentration ; Hypokalemia ; Infusions, Intravenous ; Mannitol ; Plasma

BACKGROUND: Postoperative morbidity and mortality in destroyed lung are relatively high. We tried to identify the prognostic factors affecting postoperative morbidity and mortality in destroyed lung through a retrospective study. MATERIAL AND METHOD: The retrospective study was undertaken in 112 patients who had undergone pneumonectomy or pleuropneumonectomy for destroyed lung at Severance Hospital from 1970 to 2000. We analyzed the correlation between postoperative morbidity and mortality and etiology, duration of disease, preoperative FEV1, presence or absence of preoperative empyema, operation timing, the side of operation, duration of operation, and operation type. RESULT: There were 55 men and 57 women, aged 20 to 81 years (mean 44 years). Etiologic diseases were tuberculosis in 86 patients(76.8%) including tuberculous empyema in 20 and tuberculous bronchiectasis in 4, pyogenic empyema in 12(10.7%), bronchiectasis in 12(10.7%), and lung abscess in 2(1.8%). Postoperative morbidity were 25%(n=28) and postoperative mortality was 6%(n=7). The presence of preoperative of empyema(p=0.016), pleuropneumonectomy(p=0.037) and preoperative FEV1 of less than 1.75 L(P=0.048) significantly increased the postoperative morbidity. If operation time was less than 300min, postoperative morbidity(p=0.002) and mortality(p=0.03) were significantly low. CONCLUSION: Postoperative morbidity and mortality in destroyed lung were acceptable. Postoperative morbidity and mortality were significantly low when operation time was less than 300 min. Preoperative existence of empyema, pleuropneumonectomy and preoperative FEV1 of less than 1.75 L significantly increased postoperative morbidity.
Bronchiectasis ; Empyema ; Empyema, Tuberculous ; Female ; Humans ; Lung Abscess ; Lung* ; Male ; Mortality* ; Pneumonectomy ; Retrospective Studies ; Tuberculosis

The majority of cystic lesions of the pancreas are psudocysts and a small fraction neoplastic. Failure to recognize the true nature of neoplastic cyst will lead to an incorrct treatment strategy. Ultrasonography, computerized tomography and angiography were used to distingish these lesions, but diagnostic value of ERCP is in controversy. To evaluate the diagnostic value of ERCP in cystic lesions of the pancreas, we analysed 33 cases of pancreatic cystic lesions (pseudocyst 18 cases, retention cyst 3 cases and cystic, neoplasm l2 cases) between Apr. 1985 and June 1993. In 18 cases of pseudocysts, ERP findings were communication with cyst in 8 cases (44.4%), chronic pancreatitis in 8 cases (44.4%), obstruction in 4 cases (22.2%) and displscement of pancreatic duct in 2 cases (11.1%), and ERC findings, which were perfomed in 8 cases, showed cholangitis in 3 cases (37.5%), CBD stone in 2 cases (25%), mass effect in 1 case (12.5%) and normal in 2 cases (25%). There was no communication with the cyst and pancreatic duct, except two mucinous ductal ectasia, in 12 cases of cystic neoplasms, and the other findings were displacement of pancreatic duct in 4 cases (33.3%), obstruction in 2 cases (16.7%) and normal in 4 cases (33.3%). ERC findings of cystic neoplasm were almost normal (85.7%) except 1 case of cholangitis. In conclusion, ERCP findings of pseudocysts were communication with pancreatic duct, chronic pancreatitis and biliary tract abnormality. In contrast, ERCP findings of cystic neoplasms were displacement or obstruction of pancreatic duct without communication and chronic pancreatitis, and biliary tract abnormality were rare.
Angiography ; Biliary Tract ; Cholangiopancreatography, Endoscopic Retrograde* ; Cholangitis ; Dilatation, Pathologic ; Mucins ; Pancreas ; Pancreatic Cyst* ; Pancreatic Ducts ; Pancreatitis, Chronic ; Ultrasonography

Extraosseous metastatic calcification in patients undergoing maintenance hemodialysis results from precipitation of amorphous calcium phosphate and it is characterized by extensive calcifications of periarticular soft tissues, usually around the large joints, manifested clinically by palpable and visible tumors associated with secondary hyperparathyroidism. Extraosseous metastatic calcification can be present in the heart, lungs, stomach, kidneys, skeletal muscle, and around large joints. In the present case, the patient on maintenance hemodialysis has the unusual sites of metastatic calcification, involving both shoulders, the right hip joint, and especially, sternoclavicular joint. To prevent metastatic calcification, we need to decrease calcium, phosphorus, and parathyroid hormone concentration as well as to attenuate calcium phosphorus product.
Calcium ; Heart ; Hip Joint ; Humans ; Hyperparathyroidism, Secondary ; Joints ; Kidney ; Lung ; Muscle, Skeletal ; Parathyroid Hormone ; Phosphorus ; Renal Dialysis* ; Shoulder ; Sternoclavicular Joint* ; Stomach