1.A retrospective study on related factors affecting the survival rate of dental implants.
Hee Won JANG ; Jeong Kyung KANG ; Ki LEE ; Yong Sang LEE ; Pil Kyoo PARK
The Journal of Advanced Prosthodontics 2011;3(4):204-215
PURPOSE: The aim of this retrospective study is to analyze the relationship between local factors and survival rate of dental implant which had been installed and restored in Seoul Veterans Hospital dental center for past 10 years. And when the relationship is found out, it could be helpful to predict the prognosis of dental implants. MATERIALS AND METHODS: A retrospective study of patients receiving root-shaped screw-type dental implants placed from January 2000 to December 2009 was conducted. 6385 implants were placed in 3755 patients. The following data were collected from the dental records and radiographs: patient's age, gender, implant type and surface, length, diameter, location of implant placement, bone quality, prosthesis type. The correlations between these data and survival rate were analyzed. Statistical analysis was performed with the use of Kaplan-Meier analysis, Chi-square test and odds ratio. RESULTS: In all, 6385 implants were placed in 3755 patients (3120 male, 635 female; mean age 65 +/- 10.58 years). 108 implants failed and the cumulative survival rate was 96.33%. There were significant differences in age, implant type and surface, length, location and prosthesis type (P<.05). No significant differences were found in relation to the following factors: gender, diameter and bone quality (P>.05). CONCLUSION: Related factors such as age, implant type, length, location and prosthesis type had a significant effect on the implant survival.
Dental Implants
;
Dental Records
;
Hospitals, Veterans
;
Humans
;
Kaplan-Meier Estimate
;
Male
;
Prognosis
;
Prostheses and Implants
;
Retrospective Studies
;
Survival Rate
2.The Impact of Elderly Donor in Renal Transplantation.
Pil Kyung PARK ; Oh Jung KWON ; Chong Myung KANG
The Journal of the Korean Society for Transplantation 2008;22(1):66-69
PURPOSE: Kidney transplantation from elderly donors is controversial because of decline of received renal function and increased risk of perioperative complication. METHODS: We retrospectively reviewed the records of the 676 patients from 1985 to 2006 in our center. 42 (6.2%) donors were > or =60 years old, and constitue the group 1, and 634 donors (93.8%) were <60 years old (group 2). We analysis graft survival, preoperative and postoperative creatinine, creatinine clearance, acute rejection rate, infection rate, delayed graft fucntion rate, HLA matching between groups. RESULTS: The average donor age in group 1 is 62.8 yr (60~73) and 39.3 yr (16~59) in group 2. Graft survival rate at 1, 5 and 10 years were 92%, 71%, 56% in group 1 vs 92%, 77%, 62% in group 2 (P=0.0831). There was no difference of graft survival between groups. In preoperative serum creatinine or postoperative days 3, 30 creatinine there was not difference between groups. Infection rate was 9.5% (4 patients) in group 1 vs. 7.3% (46 patients) in group 2. Acute rejection rate was 28.6% (12 patients) vs. 30.9% (196 patients). Delayed graft function (DGF) rate was 7.1% (3 patients) vs. 9.0% (57 patients). HLA-AB matching was 1.86 vs. 1.78 and HLA-DR matching was 1.12 vs. 1.06. All were not significantly different between groups. But the elderly donor group has a lower creatinine clearance at postoperative 3, 30 days (P=0.0422, 0.0231). CONCLUSION: The short and long-term survival of kidney transplantation from elderly donors (> or =60) are similar to younger donors (<60). We suggest that use of elderly donors may help to expand the donor pool in kidney transplantation.
Aged
;
Creatinine
;
Delayed Graft Function
;
Graft Survival
;
HLA-DR Antigens
;
Humans
;
Kidney
;
Kidney Transplantation
;
Rejection (Psychology)
;
Retrospective Studies
;
Tissue Donors
;
Transplants
3.Role of Placental Apoptosis on Intrauterine Growth Restriction in Placenta Previa.
Dae Joon JEON ; Hye Sung WON ; Ji Ahn KANG ; Mi Kyung KIM ; So Ra KIM ; Ji Youn CHUNG ; Pil Rymang LEE ; Ahm KIM ; Byung Moon KANG
Korean Journal of Perinatology 2001;12(4):486-494
No abstract available.
Apoptosis*
;
Placenta Previa*
;
Placenta*
4.Full mouth rehabilitation in patient with loss of vertical dimension and deep bite due to worn dentition.
Ki Hun NAM ; Pil Kou PARK ; Hee Kyung KIM ; Jeong Kyung KANG
The Journal of Korean Academy of Prosthodontics 2016;54(1):65-71
Gradual occlusal attrition is a normal process of aging. However, severe attrition causes pathogenic pulp, occlusal disharmony, functional disorder and esthetic problems. Alteration of vertical dimension should be considered for space regaining for tooth restoration, esthetic improvement or correction of occlusal relationship. Vertical dimension should be determined within the range of minimal invasive process satisfying patient's esthetic requirements and operator's functional goal. And patient's adaptation to newly determined vertical dimension should be assessed simultaneously. Deep overbite is not a simple problem of overbite, instead it is an usually complicated problem with anterior-posterior occlusal relationship. Considering these facts, appropriate restoration of edentulous part as well as improvement of anterior-posterior relationship should be performed to solve this fundamental problems. In this study, a 67 year-old male patient with many worn teeth and loss of posterior teeth was treated with removable partial denture at edentulous mandibular area to increase vertical dimension and fixed prostheses at dentulous maxillary and mandibular area. With these treatments, we attained a satisfactory result in functional and esthetic aspects as a report case.
Aging
;
Dentition*
;
Denture, Partial, Removable
;
Humans
;
Male
;
Mouth Rehabilitation*
;
Mouth*
;
Overbite*
;
Prostheses and Implants
;
Tooth
;
Vertical Dimension*
5.Etiology of Acute Pharyngotonsillitis in Children: The Presence of Viruses and Bacteria.
Jong Seok PYEON ; Kyung Pil MOON ; Jin Han KANG ; Sang Hyuk MA ; Song Mi BAE
Pediatric Infection & Vaccine 2016;23(1):40-45
PURPOSE: The purpose of this study was to investigate the etiology of acute pharygotonsillitis in pediatric patients. METHODS: Pharyngeal swabs from patients with acute pharyngotonsillitis were evaluated for viruses and bacterial organisms from March 2010 through March 2011. RESULTS: Of 615 patients, potentially pathogenic bacteria were isolated in 40 (6.5%), viruses were isolated in 310 (50.4%), and no pathogens were isolated in 267 patients (43.4%). Both viral and bacterial pathogens were found in 2 (0.3%). Of 40 patients with bacterial pathogens, group A streptococci were found in 31 (77.5%). Among 310 patients with virus infection, adenovirus was the most frequently recovered (203 patients; 65.5%), followed by rhinovirus (65 patients; 21.0%), enterovirus (43 patients; 13.9%) and coronavirus (18 patients; 5.8%). There were 25 patients who had been coinfected with 2 viruses. In viral pharyngotonsillitis, cough, rhinorrhea, conjunctivitis and diarrhea were prominent. On the other hand, pharyngeal injection and pharyngeal petechiae were prominent in bacterial pharyngotonsillitis. CONCLUSIONS: Virus infection was a big part of acute pharyngotonsillitis and there were differences in clinical manifestations among viral and bacterial infections. Therefore, we need to distinguish between virus infection and bacterial infection using clinical signs for preventing the abuse of antibiotics.
Adenoviridae Infections
;
Anti-Bacterial Agents
;
Bacteria*
;
Bacterial Infections
;
Child*
;
Conjunctivitis
;
Coronavirus
;
Cough
;
Diarrhea
;
Enterovirus
;
Hand
;
Humans
;
Purpura
;
Rhinovirus
6.Prognostic Implication of 15-Hydroxyprostaglandin Dehydrogenase Down-Regulation in Patients with Colorectal Cancer.
Pil Sung KANG ; Jin Ha KIM ; Ok In MOON ; Sung Chul LIM ; Kyung Jong KIM
Journal of the Korean Society of Coloproctology 2012;28(5):253-258
PURPOSE: Prostaglandin (PG) E2 is known to be closely related to cancer progression and is inactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH). 15-PGDH is shown to have tumor suppressor activity and to be down-regulated in various cancers, including colorectal cancer (CRC). Therefore, we evaluated the expression of 15-PGDH and its prognostic effect in patients with CRC. METHODS: 15-PGDH expression was examined by using immunohistochemistry in 77 patients with CRC. Its prognostic significance was statistically evaluated. RESULTS: Negative 15-PGDH expression was noted in 55.8% of the 77 cases of CRC. 15-PGDH expression showed no correlation with any of the various clinicopathologic parameters. The status of lymph node metastasis, tumor-node-metastasis stages, and pre-operative carcinoembryonic antigen levels showed significant prognostic effect. However, univariate analysis revealed down-regulation of 15-PGDH not to be a predictor of poor survival. The 5-year overall survival rate was 71.7% in the group with positive expression of 15-PGDH and 67.1% in the group with negative expression of 15-PGDH, but this difference was not statistically significant (P = 0.751). CONCLUSION: 15-PGDH was down-regulated in 55.8% of the colorectal cancer patients. However, down-regulation of 15-PGDH showed no prognostic value in patients with CRC. Further larger scale or prospective studies are needed to clarify the prognostic effect of 15-PGDH down-regulation in patients with colorectal cancer.
Carcinoembryonic Antigen
;
Colorectal Neoplasms
;
Down-Regulation
;
Humans
;
Hydroxyprostaglandin Dehydrogenases
;
Immunohistochemistry
;
Lymph Nodes
;
Neoplasm Metastasis
;
Oxidoreductases
;
Prognosis
;
Survival Rate
7.Management of Dissecting Aneurysm of Cervicocephalic Carotid and Vertebral Artery.
Dal Soo KIM ; Do Sung YOU ; Pil Woo HUH ; Kyung Suk CHO ; Joon Ki KANG
Korean Journal of Cerebrovascular Disease 1999;1(1):39-42
The pathogenesis of spontaneous cervicocephalic arterial dissection is still incompletely understood. The clinical presentation of the arterial dissection depends on the plane where the dissection occurred in the arterial wall. When the outer media or subadventitia is dissected, the intramural hematoma bulges outward to make dissecting aneurysm. When located in the subintima or inner media, the intramural hematoma produces narrowing or occlusion of the vessel lumen. Authors review etiopathogeness, clinical features, diagnosis and management of cerviococephalic arterial dissection.
Aneurysm, Dissecting*
;
Brain Ischemia
;
Diagnosis
;
Hematoma
;
Subarachnoid Hemorrhage
;
Vertebral Artery*
8.Anterior Cervical Interbody Fusion with or Without Plate and Screws System.
Chun Kun PARK ; Choon Keun PARK ; Kyung Suk CHO ; Pil Woo HUH ; Il Woo LEE ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1996;25(10):2052-2058
Although anterior cervical plates are thought to be good tools, their clinical results have not been compared with those of anterior cervical fusion without a plating system in the domestic scientific literature. As there are some advantages as well as shortcomings in these two surgical methods, it is imperative to know which one might be better in terms of the postoperative complications and management. Therefore, the authors reviewed 80patients undergoing anterior cervical fusion during the period of January 1992 to May 1994. Top plate placement was made in 25 and simple fusion without a plating system was applied in 55. The average follow-up period was 9.6 months. In the patients undergoing simple cervical fusion, thirty-two patients(58%) needed rigid braces such as halo braces and Minerva casts for 3 months postoperatively. Thirteen patients(24%) showed graft complications including graft extrusion, whereas patients undergoing plate placement needed only semi-rigid Philadelphia braces for 4 to 8 weeks pos toperatively. Two patients(8%) showed graft setting and screw breakage without any indication of reoperation. However there appeared no difference in the immediate postoperative course of clinical symptoms and the fusion rate(95 vs 96%) at the final follow-up day between the simple fusion and the plate placement patients. The authors conclude that a plating system in anterior cervical fusion may be safe in spite of more extensive operations, and is more likely to offer postoperative stability in the cervical spine and early ambulation and rehabiliation without rigid braces.
Braces
;
Early Ambulation
;
Follow-Up Studies
;
Humans
;
Postoperative Complications
;
Reoperation
;
Spine
;
Transplants
9.Anterior Cervical Interbody Fusion with or Without Plate and Screws System.
Chun Kun PARK ; Choon Keun PARK ; Kyung Suk CHO ; Pil Woo HUH ; Il Woo LEE ; Joon Ki KANG
Journal of Korean Neurosurgical Society 1996;25(10):2052-2058
Although anterior cervical plates are thought to be good tools, their clinical results have not been compared with those of anterior cervical fusion without a plating system in the domestic scientific literature. As there are some advantages as well as shortcomings in these two surgical methods, it is imperative to know which one might be better in terms of the postoperative complications and management. Therefore, the authors reviewed 80patients undergoing anterior cervical fusion during the period of January 1992 to May 1994. Top plate placement was made in 25 and simple fusion without a plating system was applied in 55. The average follow-up period was 9.6 months. In the patients undergoing simple cervical fusion, thirty-two patients(58%) needed rigid braces such as halo braces and Minerva casts for 3 months postoperatively. Thirteen patients(24%) showed graft complications including graft extrusion, whereas patients undergoing plate placement needed only semi-rigid Philadelphia braces for 4 to 8 weeks pos toperatively. Two patients(8%) showed graft setting and screw breakage without any indication of reoperation. However there appeared no difference in the immediate postoperative course of clinical symptoms and the fusion rate(95 vs 96%) at the final follow-up day between the simple fusion and the plate placement patients. The authors conclude that a plating system in anterior cervical fusion may be safe in spite of more extensive operations, and is more likely to offer postoperative stability in the cervical spine and early ambulation and rehabiliation without rigid braces.
Braces
;
Early Ambulation
;
Follow-Up Studies
;
Humans
;
Postoperative Complications
;
Reoperation
;
Spine
;
Transplants
10.Effect of terazosin on blood pressure and serum lipids in nild to moderate hypertension.
Jong Pil KIM ; In Koo KANG ; Seung Cheol SHIM ; Ock Chan LEE ; Kyung Soo KIM ; Jeong Hyun KIM ; Heon Kil IM ; Bang Hun LEE ; Chung Kyun LEE
Korean Circulation Journal 1993;23(3):454-460
BACKGROUND: We evaluated the antihypertensive effect, safety and effect on serum lipids of terazosin, second generation alpha1-blocker. METHODS: Terazosin 1-4mg was adminstered once daily in 20 patients for 12 weeks with dose titration every 2 weeks. RESULTS: 1) The systolic and diastolic blood pressure were decreased from 170.0+/-13.0/104.0+/-6.0mmHg to 144.0+/-13.3/88.0+/-5.6mmHg(p<0.01), but the heart rate and body weight were independant of terazosin administration. 2) Total cholesterol was decreased significantly from 209.9+/-33.5mg/dL to 194.6+/-30.1mg/dL after 12 weeks treatment(p<0.05), triglyceride was decreased significantly from 185.4+/-37.0mg/dL to 168.9+/-35.0mg/dL(p<0.05). and LDL-cholesterol was decreased significantly from 134.5+/-31.9mg/dL to 122.7+/-29.9mg/dL(p<0.05), but HDL-cholesterol was increased significantly from 37.8+/-5.6mg/dL to 40.6+/-5.5mg/dL(p<0.05). 3) The adverse effects of terazosin were dizziness in 2, headache in 2, asthenia in 1, peripheral edema in 1 and skin rash in 1 patient, but were not troublesome enough to stop medication. CONCLUSIONS: Terazosin 1-4mg once daily regimen was effective and safe as an antihypertensive agent, and moreover terazosin has favorable effects on serum lipids.
Asthenia
;
Blood Pressure*
;
Body Weight
;
Cholesterol
;
Dizziness
;
Edema
;
Exanthema
;
Headache
;
Heart Rate
;
Humans
;
Hypertension*
;
Triglycerides