PURPOSE: The aim of this retrospective study is to analyze the relationship between local factors and survival rate of dental implant which had been installed and restored in Seoul Veterans Hospital dental center for past 10 years. And when the relationship is found out, it could be helpful to predict the prognosis of dental implants. MATERIALS AND METHODS: A retrospective study of patients receiving root-shaped screw-type dental implants placed from January 2000 to December 2009 was conducted. 6385 implants were placed in 3755 patients. The following data were collected from the dental records and radiographs: patient's age, gender, implant type and surface, length, diameter, location of implant placement, bone quality, prosthesis type. The correlations between these data and survival rate were analyzed. Statistical analysis was performed with the use of Kaplan-Meier analysis, Chi-square test and odds ratio. RESULTS: In all, 6385 implants were placed in 3755 patients (3120 male, 635 female; mean age 65 +/- 10.58 years). 108 implants failed and the cumulative survival rate was 96.33%. There were significant differences in age, implant type and surface, length, location and prosthesis type (P<.05). No significant differences were found in relation to the following factors: gender, diameter and bone quality (P>.05). CONCLUSION: Related factors such as age, implant type, length, location and prosthesis type had a significant effect on the implant survival.
Dental Implants ; Dental Records ; Hospitals, Veterans ; Humans ; Kaplan-Meier Estimate ; Male ; Prognosis ; Prostheses and Implants ; Retrospective Studies ; Survival Rate

PURPOSE: Kidney transplantation from elderly donors is controversial because of decline of received renal function and increased risk of perioperative complication. METHODS: We retrospectively reviewed the records of the 676 patients from 1985 to 2006 in our center. 42 (6.2%) donors were > or =60 years old, and constitue the group 1, and 634 donors (93.8%) were <60 years old (group 2). We analysis graft survival, preoperative and postoperative creatinine, creatinine clearance, acute rejection rate, infection rate, delayed graft fucntion rate, HLA matching between groups. RESULTS: The average donor age in group 1 is 62.8 yr (60~73) and 39.3 yr (16~59) in group 2. Graft survival rate at 1, 5 and 10 years were 92%, 71%, 56% in group 1 vs 92%, 77%, 62% in group 2 (P=0.0831). There was no difference of graft survival between groups. In preoperative serum creatinine or postoperative days 3, 30 creatinine there was not difference between groups. Infection rate was 9.5% (4 patients) in group 1 vs. 7.3% (46 patients) in group 2. Acute rejection rate was 28.6% (12 patients) vs. 30.9% (196 patients). Delayed graft function (DGF) rate was 7.1% (3 patients) vs. 9.0% (57 patients). HLA-AB matching was 1.86 vs. 1.78 and HLA-DR matching was 1.12 vs. 1.06. All were not significantly different between groups. But the elderly donor group has a lower creatinine clearance at postoperative 3, 30 days (P=0.0422, 0.0231). CONCLUSION: The short and long-term survival of kidney transplantation from elderly donors (> or =60) are similar to younger donors (<60). We suggest that use of elderly donors may help to expand the donor pool in kidney transplantation.
Aged ; Creatinine ; Delayed Graft Function ; Graft Survival ; HLA-DR Antigens ; Humans ; Kidney ; Kidney Transplantation ; Rejection (Psychology) ; Retrospective Studies ; Tissue Donors ; Transplants

No abstract available.
Apoptosis* ; Placenta Previa* ; Placenta*

Gradual occlusal attrition is a normal process of aging. However, severe attrition causes pathogenic pulp, occlusal disharmony, functional disorder and esthetic problems. Alteration of vertical dimension should be considered for space regaining for tooth restoration, esthetic improvement or correction of occlusal relationship. Vertical dimension should be determined within the range of minimal invasive process satisfying patient's esthetic requirements and operator's functional goal. And patient's adaptation to newly determined vertical dimension should be assessed simultaneously. Deep overbite is not a simple problem of overbite, instead it is an usually complicated problem with anterior-posterior occlusal relationship. Considering these facts, appropriate restoration of edentulous part as well as improvement of anterior-posterior relationship should be performed to solve this fundamental problems. In this study, a 67 year-old male patient with many worn teeth and loss of posterior teeth was treated with removable partial denture at edentulous mandibular area to increase vertical dimension and fixed prostheses at dentulous maxillary and mandibular area. With these treatments, we attained a satisfactory result in functional and esthetic aspects as a report case.
Aging ; Dentition* ; Denture, Partial, Removable ; Humans ; Male ; Mouth Rehabilitation* ; Mouth* ; Overbite* ; Prostheses and Implants ; Tooth ; Vertical Dimension*

This study was performed to investigate the influence of epidermal growth factor (EGF) on preimplantation development, implantation, and expression of epidermal growth factor receptor (EGFR) in mouse embryos. Riverse transcription-polymerase chain reaction (RT-PCR) has been used to examine the presence of transcripts. Following reverse transcription, strategically designed nested primers, optimised for specificity, were used for amplification from the cDNA equivalent of a single embryo. The products were then verified by restriction enzyme digestion and sequence analysis. Eight-cell stage mouse embryos were cultured for 48hrs with EGF at concentrations of 0.1, 1.0, 10 and 100 ng/ml. Embryos not treated with EGF were served as control. The percentages of embryos which developed to the expanded, hatched blastocyst stage and in vitro implantation at 48hrs were determined. The percentages of fully expanded murine blastocysts at 48hrs in all EGF treated group were not significantly different from the control. The percentages of hatched blastocysts were significantly higher in EGF treatment group at 0.1ng/ml (90.7%), 10 ng/ml (89.3%) compared to the control (82.1%; p < 0.05, p < 0.05). The percentages of implanted blastocyst in vitro were significantly higher following incubation with EGF at concentrations of O.lng/ml (38.1%; p < 0.05), 1.0ng/ml (33.3%; p < 0.05), 10ng/ml (22.2%; p < 0.05) compared to the control (10.7%). Embryo development and implantation in vitro were not significantly inhibited or enhanced in cultures supplemented with 100ng/ml EGF compared to the control. The mRNA concentration of EGFR in embryos treated with 0.1ng/ml of EGF were significantly higher than those of the control and other EGF treatment groups. The implantation rate and mRNA concentration of EGFR in embryos treated with 0.1ng/ml of EGF group were significantly higher than those of other treatd groups. In conclusion, EGF may have a stimulatory role in embryonic development, implantation and expression of EGFR in embryo itself with concentration-specific manner. These results suggest that EGF may act directly on the mouse embryo and favor its implantaion, irtespective of the presence ar absence of the endometrium.
Animals ; Blastocyst ; Digestion ; DNA, Complementary ; Embryonic Development ; Embryonic Structures* ; Endometrium ; Epidermal Growth Factor* ; Female ; Mice* ; Pregnancy ; Receptor, Epidermal Growth Factor ; Reverse Transcription ; Rivers ; RNA, Messenger ; Sensitivity and Specificity ; Sequence Analysis

Osteoma is the most common benign tumor of the paranasal sinuses and the frontal sinus is the most frequently involved site. Osteomas are slow growing osteoblastic lesions commonly seen in the outer table of the calvarium, the mandible, the frontal and ethmoid sinus, and occasionally in tubular bones. They are usually detected during the second to fifth decades of life, and reported ratio of male to female is 1.5:1 to 2:1. The symptoms of osteomas are usually developed as gradual growth. They are headaches, facial pain, proptosis, decreased visual acuity, chemosis, diplopia, epiphora, nonpulsating exophthalmus, and transient blindness. Posterior intracranial extension of a frontoethmoid osteoma may lead to brain abscess, intracranial mucocele, tension pneumocephalus. We experienced a 60-year-old male patient who came to the emergency room with acute and severe left periorbital swelling, red eye, and epiphora lasted for 10 days. In a plain radiographs and computerized tomographic scans, a 2.5 x 2.5 x 3.0 cm well marginated mass impressed by osteoma in frontoethmoidal sinus was detected. After the symptoms subsided by conservative treatment, total excision was made by bicoronal approach. Authors reported a frontoethmoidal osteoma presenting periorbital cellulitis without orbital mucocele, which is very rare symptom.
Blindness ; Brain Abscess ; Cellulitis* ; Diplopia ; Emergency Service, Hospital ; Ethmoid Sinus ; Exophthalmos ; Facial Pain ; Female ; Frontal Sinus* ; Headache ; Humans ; Lacrimal Apparatus Diseases ; Male ; Mandible ; Middle Aged ; Mucocele ; Orbit ; Osteoblasts ; Osteoma* ; Paranasal Sinuses ; Pneumocephalus ; Skull ; Visual Acuity

PURPOSE: The purpose of this study was to investigate the etiology of acute pharygotonsillitis in pediatric patients. METHODS: Pharyngeal swabs from patients with acute pharyngotonsillitis were evaluated for viruses and bacterial organisms from March 2010 through March 2011. RESULTS: Of 615 patients, potentially pathogenic bacteria were isolated in 40 (6.5%), viruses were isolated in 310 (50.4%), and no pathogens were isolated in 267 patients (43.4%). Both viral and bacterial pathogens were found in 2 (0.3%). Of 40 patients with bacterial pathogens, group A streptococci were found in 31 (77.5%). Among 310 patients with virus infection, adenovirus was the most frequently recovered (203 patients; 65.5%), followed by rhinovirus (65 patients; 21.0%), enterovirus (43 patients; 13.9%) and coronavirus (18 patients; 5.8%). There were 25 patients who had been coinfected with 2 viruses. In viral pharyngotonsillitis, cough, rhinorrhea, conjunctivitis and diarrhea were prominent. On the other hand, pharyngeal injection and pharyngeal petechiae were prominent in bacterial pharyngotonsillitis. CONCLUSIONS: Virus infection was a big part of acute pharyngotonsillitis and there were differences in clinical manifestations among viral and bacterial infections. Therefore, we need to distinguish between virus infection and bacterial infection using clinical signs for preventing the abuse of antibiotics.
Adenoviridae Infections ; Anti-Bacterial Agents ; Bacteria* ; Bacterial Infections ; Child* ; Conjunctivitis ; Coronavirus ; Cough ; Diarrhea ; Enterovirus ; Hand ; Humans ; Purpura ; Rhinovirus

Patients who are devastated neurologically or medically after aneurysmal subarachnoid hemorrhage(SAH) are described as 'poor grade' patients. More recent studies have documented that the initial hemorrhage is by far the most important determinant of outcome after aneurysmal subarachnoid hemorrhage. This review mainly includes hemodynamics and suspected mechanisms of acute brain injury after aneurysmal SAH, particularly in special reference to increased intracranial pressure and cerebral ischemia during and after SAH.
Aneurysm ; Brain Injuries ; Brain Ischemia ; Hemodynamics* ; Hemorrhage ; Humans ; Intracranial Pressure ; Subarachnoid Hemorrhage*

The pathogenesis of spontaneous cervicocephalic arterial dissection is still incompletely understood. The clinical presentation of the arterial dissection depends on the plane where the dissection occurred in the arterial wall. When the outer media or subadventitia is dissected, the intramural hematoma bulges outward to make dissecting aneurysm. When located in the subintima or inner media, the intramural hematoma produces narrowing or occlusion of the vessel lumen. Authors review etiopathogeness, clinical features, diagnosis and management of cerviococephalic arterial dissection.
Aneurysm, Dissecting* ; Brain Ischemia ; Diagnosis ; Hematoma ; Subarachnoid Hemorrhage ; Vertebral Artery*

PURPOSE: Prostaglandin (PG) E2 is known to be closely related to cancer progression and is inactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH). 15-PGDH is shown to have tumor suppressor activity and to be down-regulated in various cancers, including colorectal cancer (CRC). Therefore, we evaluated the expression of 15-PGDH and its prognostic effect in patients with CRC. METHODS: 15-PGDH expression was examined by using immunohistochemistry in 77 patients with CRC. Its prognostic significance was statistically evaluated. RESULTS: Negative 15-PGDH expression was noted in 55.8% of the 77 cases of CRC. 15-PGDH expression showed no correlation with any of the various clinicopathologic parameters. The status of lymph node metastasis, tumor-node-metastasis stages, and pre-operative carcinoembryonic antigen levels showed significant prognostic effect. However, univariate analysis revealed down-regulation of 15-PGDH not to be a predictor of poor survival. The 5-year overall survival rate was 71.7% in the group with positive expression of 15-PGDH and 67.1% in the group with negative expression of 15-PGDH, but this difference was not statistically significant (P = 0.751). CONCLUSION: 15-PGDH was down-regulated in 55.8% of the colorectal cancer patients. However, down-regulation of 15-PGDH showed no prognostic value in patients with CRC. Further larger scale or prospective studies are needed to clarify the prognostic effect of 15-PGDH down-regulation in patients with colorectal cancer.
Carcinoembryonic Antigen ; Colorectal Neoplasms ; Down-Regulation ; Humans ; Hydroxyprostaglandin Dehydrogenases ; Immunohistochemistry ; Lymph Nodes ; Neoplasm Metastasis ; Oxidoreductases ; Prognosis ; Survival Rate