PURPOSE: To determine the MR imaging findings for the differentiation of tuberculous spondylitis(TS) and pyogenic spondylitis(PS) with emphasis on the shape and MR signal characteristics of paraspinal mass. MATERIALS AND METHODS: We obtained spin-echo T1- and T2-weighted MR images of 63 surgically proved cases of TS and 15 casesof PS. Gadopentetate dimeglumine(Gd)-enhanced T1-weighted MR images in 37 cases of TS and in all 15 cases of PS were also obtained. Paraspinal mass formation, the size, shape and Gd-enhancing pattern of this mass and penetration of paraspinal ligaments by inflammatory tissue were analyzed. RESULTS: Paraspinal mass was found inboth TS(63/63) and PS(9/15). The mean longitudinal dimension of this mass was 4.3 vertebral body heights in TS and1.8 in PS. The margin of the mass was smooth in TS due to subligamentous spread of inflammation, while PS showedan irregular margin and invaded the para-aortic or para-caval space(9/15) due to penetration of inflammatory tissue through the paraspinal ligament. In the lumbar spine, however, TS showed focal penetration of the paraspinal ligament and formed psoas abscesses. After Gd enhancement, TS showed irregular thick or uniformly thinrim enhancement(35/37), suggesting caseation necrosis and cold abscess, while PS showed diffuse enhancement, suggesting abundant granulation tissue. CONCLUSION: MR imaging findings helpful for the differentiation of TS andPS were size, shape and enhancing pattern of paraspinal mass and penetration of paraspinal ligament by inflammatory tissue.
Abscess ; Body Height ; Granulation Tissue ; Inflammation ; Ligaments ; Magnetic Resonance Imaging* ; Necrosis ; Psoas Abscess ; Spine ; Spondylitis*

To evaluate the role of MR in the examination of Legg-Calve-Perthes(LCP) disease, we retrospectively analysed the signal intensity of the osseous lesion, thickness of the articlar cartilage, change of surrounding soft tissue. Joint effusion and femoral head containment in 32 cases of LCP diseases in 27 patients. The bony lesion was limited witin the epiphysis in 19 cases(59%) and extended to the physis and metaphysis in 13 cases(41%). The epiphyseal lesion showed homogeneous(26/32) or heterogeneous(6/32) low signal intensity(ST) on T-1 weighted images(T1WI). And homogeneous (16/28) or heterogeneous(12/28)low SI on T-2 weighted images(T2WI). The metaphyseal lesion showed low SI(13/13) on T1WI, and low(9/11) or iso(3/11)SI on T2WI. Associated metaphyseal cyst showed low SI on T1WI and high SI on T2WI. An althought physeal involvement(13/32) was indistinct, the lesion showed increased SI on both T1 and T2WI. Thickening of articular cartilage(32/32), swelling f the ligamentum teres(7/32), synovial hypertrophy(7/32) and joint effsion(27/32) were demonstrated. Lateral subluxation of the femoral head on coronal image indicated incongruity of the femoral head in 25cases(78%) We conclude that MR is an useful tool for the diagnosis as well as treatment planning in LCP disease.
Cartilage ; Containment of Biohazards ; Diagnosis ; Epiphyses ; Head ; Humans ; Joints ; Legg-Calve-Perthes Disease* ; Retrospective Studies

No abstract available.
Oncogene Proteins* ; Oncogenes* ; Teratocarcinoma*

35 neurogenic tumors of the thorax were analyzed with plain film and CT scan. Radiological analysis emphasizedshape, location calcification, bone change, pleural change in plain film and calcification, cystic change, bonechange, pleural change, presence of contrast enhancement in CT scan. The results were as follows; 1. Age may bethe most important clinical factor for differential diagnosis. 2. Plain film findings(35 cases); 1) The mostcommon shape in the ganglion series tumor (ganglioneuroma, ganglioneuroblastoma, neuroblastoma), was elongation(80%) and these tumors generally had tapered borders(50%). In contrast with those of the genglion series, nervesheath tumors(schwannoma, neurofibroma, malignant Schwannoma) showed a definite tendency to be roudn (95%) and thesulcus effect was more frequetnly seen(67.5%). Most of the masses were smooth. The lobulated masses were commonlymalignant ganglion series tumors. 2) Though overall incidence of calcification was low(8.6%), it was observed morefrequently in ganglion series tumors(20%). 3) Associated bony abnormality were generally observed in large tumorsabove 5cm in long axis, especially in neuroblastoma and ganglioneuroblastoma. 4) Tumors showed pleural effusionwere all malignant. 3. CT findings (17 cases); 1) The overall incidence of cystic change of the mass was 23.6%. Itwas most common in Schwannoma(60%). 2) The contrast enhancement was noted in 64.7%. It's degree was variable andshowed no predilection to any specific tumors. 3) The incidence of calcification, associated bony abnormality andpleural effusion were similiar to plain film. Confident specific diagnosis can be made in most of the neurogenictumors of the thorax by shape of the mass in plain film and internal architecture in CT combined with patient'sage as clinical information.
Diagnosis ; Diagnosis, Differential ; Ganglion Cysts ; Ganglioneuroblastoma ; Incidence ; Neuroblastoma ; Neurofibroma ; Thorax ; Tomography, X-Ray Computed

PURPOSE: To evaluate the MR imaging findings and gadolinium enhancing patterns of Kienboeck's disease. MATERIALS AND METHODS: Thirteen patients with Kienb ck's disease were included in this study. T1 and T2 or T2*weighted images(WI) were taken in all patients and gadolinium enhancement was performed in six patients. We compared MR signal intensity of lunates with that of normal bone marrow. MR imaging findings and stages accordingto Lichtman's classification were correlateds and we evaluated the enhancing patterns of the lunates and synovia. RESULTS: Stage II was found in five patients, stage III in seven, and stage IV in one. T1WIs showed low or focaliso signal intensity in all patients. T2WI showed low signal intensity in three patients and focal iso or focal high signal intensity in ten. There were no significant correlations between the signal intensity of lunates and stages. Synovial enhancement was detected in five patients. In four, the areas of focal iso or high signal intensity on T2WI were the enhanced areas of lunates. CONCLUSION: Kienb ck's disease showed low signal intensityon T1WI in all patients and variable signal intensity on T2WI. There was no significant correlation between MRsignal intensity and Lichtman's stage. Synovia and the areas of focal iso or high signal intensity on T2WI were frequently enhanced.
Bone Marrow ; Classification ; Gadolinium ; Humans ; Magnetic Resonance Imaging* ; Necrosis ; Osteonecrosis* ; Synovial Fluid

No abstract available.
Apoptosis* ; Prostate* ; Prostatic Hyperplasia*

A 64-year-old male was admitted due to weight loss of 5kg during a month. Chest X-ray showed two large, lobulated masses on both lower lobe. Chest CT showed ill-defined, multilobulated mass on left lower lobe and r-regular, relatively homogenous mass with air-bronchogram on right lower lobe. Left lower lobectomy and right lower lobectomy was performed sequentially with three months intervaL Microscopic findings showed squamous cell carcinoma of both mass. It was thought that this patient had synchronous double primary lung cancer.
Carcinoma, Squamous Cell ; Humans ; Lung Neoplasms ; Lung* ; Male ; Middle Aged ; Thorax ; Tomography, X-Ray Computed ; Weight Loss

Renal arterial embolization was induced experimentally in rabbits using autologous blood clot, Gelfoam, bariumsulfate, Ivalon(Polyvinyl alcohol)and ethanol. Microvascular changes were studied angiographically,microangiographically and histopathologically. The results were as follows: 1. The microangiographic findings ofrenal artery embolization were arterial occlusion, irregular arrangement, spiralling, dilatation, narrowing andcollateral vessel formation. 2. Recanalization of embolized vessels were noted after injection of autologous bloodclot and Gelforam only. 3. Collateral vessel formations were demonstrated in entire cases of renal arterialembolization (36/37). 4. After injection of Ivalon, recanalization of embolized vessel was not demonstrated butcollateral vessel formation were demonstrated microangiographically in all cases. 5 After injection of ethanol,collateral vessels were poorly developed microangiographically than other groups. 6. Embolic effect of ethanol wasnoted in central vessel but as well as in peripheral vessel. It was considered that ethanol is the most effectiveagent for permanent renal arterial occlusion.
Arteries ; Dilatation ; Ethanol ; Gelatin Sponge, Absorbable ; Rabbits

PURPOSE: Chest irradiation leads to a significant cardiac injury in a number of patients. To prevent, or to reduce the risk of radiation-induced cardiac injury, pentosifylline(PTX), a haemorrheologic agent that improves the blood flow through small blood capillaries has been employed. MATERIALS AND METHODS: One hundred and eighty ICR mice were divided into three study groups : control, radiation alone, and radiation-pentoxifylline. Each group was subdivided into 12 subgroups: 1,3,6 and 10 days and 2, 3, 4, 6, 8, 12, 16 and 20 weeks y observation period after irradiation. The total 15 Gy of radiation was delivered in a single fraction ghrough anterior mediastinal port. Pentoxifylline was injected subcutaneously daily 50mg/k to the back of the mice from the first day of irradiation throughout the observation period. The mice of each group after a certain observation period were sacrificed and sectioned for histopathologic examination of the heart. RESULTS: he findings of acute radiation-induced carditis i.e., heterohpilic infiltration and vacuolization and ballooning of endotherlial cells were onserved upto weeks and reduced sharply afterwards. The late radiation effects including pericarditis with mononuclear cell infiltration, pericardial fibrosis, endothelial cell changes, myocardial degenerationa dn fibrosis present from 4 weeks onwards after irradiation but with various degree of severity. The overall process of pathologic changes of radiation-pentoxify-acute stage was relatively short and the severity of late cardiac toxicity was much lesser compared with those of radiation alone group. CONCLUSION: Pentoxifyllline can effectively reduce the late radiation-induced cardiac injury and resolve the acute effects relatively rapidly.
Animals ; Capillaries ; Endothelial Cells ; Fibrosis ; Heart ; Humans ; Mice ; Mice, Inbred ICR* ; Myocarditis ; Pentoxifylline* ; Pericarditis ; Radiation Effects ; Thorax

No abstract available.
Hypertension, Renovascular*