Porokeratosis is an uncommon autosomally dominant inher ted disorder. Clinically, it is characterized by nonhealing plaques that develop most comnorly on the limbs. We report a case of disseminated superficial porokeratosis in immunosuppre sed kidney transplant recipient. An abrupt and extensive eruption of porokeratosis was observed in a 46-year-old man 7 months after renal transplantation, while being treated with cyclosporin A and prednisone. The histological features were essentially the same as the typical cornoid lamella. Immunosuppression may exacerbate or initiate the developm nt of porokeratosis in patients predisposed to alterations of cutaneous growth dynamics.
Cyclosporine ; Extremities ; Humans ; Immunosuppression ; Kidney Transplantation ; Kidney* ; Middle Aged ; Porokeratosis* ; Prednisone ; Transplantation*

Tinea faciale is a dermatophyte infection of glabrous skin of the face except moustache and beard areas of the adult male. Generally it is not considered to be unique entity, and is included under Tinea corporis. However, T. faciale is somewhat different from T. corporis in its clinical manifestation, age and sex distribution and composition of causative fungi. Because superficial fungal infection of the face has not been emphasized, there is a low index of suspicion and often incorrect diagnoses are made. This clinical and mycological investigation was made with 36 cases of Tinea faciale among out-patients in dermatologic clinic of St. Pauls hospital, Catholic Medical College, from October, 1980 to September, 1981. Following results were obtained: 1. The incidence of Tinea. faciale was 0.67% among 5,406 out-patients and 3.7% among 973 superficial fungal infections. 2. The ratio of male to female patient was 1: 2.6 and incidence rate among divided age groups was the highest in under 9(36.1%) and 10-19(16.7%), 20-29(16.7%) in order(Table 1). 3. Central clearing was showed in 43.5% of the patients, annular or circular features in 65.2%, scales in 69.6%, papules in 39.1%, pustules in 17.4% and 73.9% of the patients had singie lesion(Table 3). 4. Coexisting fungal infection was found in 10 patients(27.8%) among 36 cases a,nd the most common coexisting fungus was Microsporum canis (Table 6). 5. The incidence of causative fungi in descending order were as follows: Microsporum canis(43.8%), Trichophyton rubrum (25%), Trichophyton mentagrophyte(15.6%) Microsporum gypaeum(9.4%), Trichophyton interdigitale(6.2%) (Table 4).
Adult ; Arthrodermataceae ; Diagnosis ; Female ; Fungi ; Humans ; Incidence ; Male ; Microsporum ; Outpatients ; Sex Distribution ; Skin ; Tinea* ; Trichophyton ; Weights and Measures

No abstract available.

No abstract available.

BACKGROUND: One of the most, probable pathogenesis of vitiliga is autoimmune. Systemic cor tico st,eroids suppress immunity and may arrest the progression of vitiligo and lead to repigmentation. OBJECTIVE: We have assessed the clinical effect of a oral small oral dose of corticosteroid to minimize side effects in vitiligo patients. METHODS: Thirty four patients(9;male, 25;female) with vitiligo were evaluated in this study. The patients took 7.5mg-20mg prednisolone initially for 2 months and then the dosage was tapered to half of the initial dosiat the 3rd month and half of dose of 3rd month for the last 4th month. We compared the effcct of treatment of vitiligo before and aft.er the study by photographs. and side efferts were issessed at. 1, 2, 3 and 4 month. RESULTS: The arrest of the progression of vitiligo was noticed in 79% of patients and repigmentation was noticed in 59% of patients which is statistically significant. The effect, of treatment according to extent, duiation, type, and site of vitiligo were not statistically significant. The side effects of treatment were minimal and did not affect the course of treatment. CONCLUSION: Small doses of iral corticosteroids are effective without any significant side effects in preventing progression and loiiduce repigmentation of active spreading vitiligo and generalized type of vitiligo that is difficult to treat with topical corticosteroids.
Adrenal Cortex Hormones* ; Humans ; Prednisolone ; Vitiligo*

Cutaneous horn is a clinical decription for a cohesive mass of cornified mterial protruding from the surface of the skin. The incidence of cutancous horn is relaively rare and the lesion is usually single, The predilection sites are known to be the exposed area of the skin, that is, face, ear, dorsum cf hand etc. Soles are reported as the least common site of the cutaneous horn. Here, we report two cases of cutaneous horn. The one was a 49 year old schzophrenic male who had multiple cone shaped protrusions on hoth soles for 10 year. The other was 17 year old, boy who had a single cornified protrusion on the left forhead. The histopa.thologic findings from the base of two cases were consistent with benign hyperplastic epithelium.
Adolescent ; Animals ; Ear ; Epithelium ; Hand ; Horns* ; Humans ; Incidence ; Male ; Middle Aged ; Skin

BACKGROUND: Epidermal grafting using cryotherapy for recipient sites is in widespread use. However the peripheral hypopigmented haloes that occur around the recipient sites require prolon gation of the treatment period. OBJECTIVE: We used a CO2 laser to remove the epidermis of the recipient sites for betteri results. METHODS: We treated lie localized vitiligo patients with CO2 laser to remove t.he epidermis and grafted suction blister rooves. We observed repigmentation and complications 1 month later. RESULTS & CONCLUSIONS : The superiority of this method is demonstrated by the fact 1) all prodedures can be completed on the day of operation 2) the incidence of hypertrophic scar and peripheral hypopigmented halos can be observed.The problems of this method are 1) uneven repigmentation of recipient. sites 2) hyperpigrnentation of recipient sites
Blister ; Cicatrix, Hypertrophic ; Cryotherapy ; Epidermis* ; Humans ; Incidence ; Lasers, Gas* ; Suction ; Transplants* ; Vitiligo*

Leiomyoma Cutis is an unusual benign tumor of smooth muscle derivecl either from the arrector pili muscle, from the media of blood vesseles, or from smooth muscles of scrotum, labia or nipple. Two casea of leiomyoma cutis confirmed by H&E stain and Massons stain is presented, one with lesion on the left thigh and the ather with lesion of the left ankle. The first case was a 49 year-old female with solitary pinhead sized subcutaneous firm mass with intermittent pain and tenderess for 10 months, The second case waa a 36 year-old female with painful solitary peanut sized firm nodule which had pinkish center of 1 year duration.
Adult ; Ankle ; Blood Vessels ; Female ; Humans ; Leiomyoma* ; Middle Aged ; Muscle, Smooth ; Nipples ; Scrotum ; Thigh

Microsporum gypseum, long considered to be of animal origin, has recently been found to be soil inhabitating fungus and abundant in soil throughout the world. M. Gypseum infections tend to increase nowadays in Korea. Nineteen cases of ringworm caused by M. gypseum were reported in Korean literature until 1980 to the best of our knowledge. We present 5 cases of M. gypseum infection confirmed by culture findings on Sabouraud agar media and microscopic examination. The first case was 4 year-old boy with solitary coin sinzed pruritic annular erythernatous plaque ontaining papules, pustules and scales on the right cheek of on month duration. The second case, 7 year-old boy, had solitary walnut sized ovoid plaque consisted with papulopustules, oozing and peripheral scaling on right cheek of one month duration. The third case, 5 year-old boy, had solitary egg sized pruritic erythematous plaque with papuIes, scales and crust on the right lower leg of three weeks duration. The fourth case, 63 year-old female, had solitary egg sized sharply demarcated erythematious scaly patch with central clearing on nose and. nasolabial area of 10 days duration. The last case was 2 year-old girl with solitary coin sized annular erythematous scaly pIaque on left lower leg of two weeks duration.
Agar ; Animals ; Cheek ; Child ; Child, Preschool ; Female ; Fungi ; Humans ; Juglans ; Korea ; Leg ; Male ; Microsporum* ; Middle Aged ; Nose ; Numismatics ; Ovum ; Seoul* ; Soil ; Tinea ; Weights and Measures

Acanthoma fissuratum is a localized thickening of the skin in response to pressure by an eyeglass frame and usually occurs on the retroauricular fold, superior auricular crease, or bridge of the nose. The definitive diagnosis can be confirmed by characteristic clinical and histopathological features in association with anamnestic data. Herein we report a case of acanthoma fissuratum developing on an unusual site-the mucosa of the upper lip and it was successfully treated with simple excision.
Acanthoma* ; Diagnosis ; Lip* ; Mucous Membrane* ; Nose ; Skin