1.Studies on the Effects fo Topically Applied Ginseng Saponin on Human Skin: III. Evaluation of anti-inflammatory effect.
Kyung Soo LEE ; Joong Kwan KIM
Korean Journal of Dermatology 1980;18(1):39-42
The therapeutic properties of Ginseng have been known as popular Chinese midecine since time immemorial. It has been used in Korea, China, Tibet, Indonesia and India for thousands of years under various presentations, such as tes, tinctures, wines, pills, and unguents for the prevention of aging, tireness, headaches, amnesia, tuberculosis, diabetes, illness of the liver, heart, kidneys, nervous system etc. The main effective component of Ginseng has recently been considered to be saponins according to the chemical studies by Shibata's group and the pharmacological studies by Takagi et al., and also through the studies of Brekhman. The purpose of this study is to evaluate the response of topically applied Ginseng total saponin against inflammation. To induce the inflammation of skin the backs of 20 volunteers were treated with 10% sodium lauryl sulfate solution under occlusion for one hour. After removal of sodium lauryl sulfate. Gineseng total saponin ointment in various concentrations(2.5, 5, 10%) is topically applied under occlusion for 48 hours. Erythema on the areas treated with Ginseng total saponin ointment was significantly reduced than the control area. It is suggested that Ginseng total saponin has an anti-inflammatory effect on the inflammation of skin induced by sodium lauryl sulfate.
Aging
;
Amnesia
;
Asian Continental Ancestry Group
;
China
;
Erythema
;
Headache
;
Heart
;
Humans*
;
India
;
Indonesia
;
Inflammation
;
Kidney
;
Korea
;
Liver
;
Nervous System
;
Ointments
;
Panax*
;
Saponins*
;
Skin*
;
Sodium Dodecyl Sulfate
;
Tibet
;
Tuberculosis
;
Volunteers
;
Wine
2.The Histopathologic Observation in Guinea pig Skin with Local Injection of Bleomycin.
Kyung Soo LEE ; Joong Hwan KIM
Korean Journal of Dermatology 1979;17(5):311-317
Bleoxycin is known to have good therapeutic effect on verrucae, which has been used for varioua malignant turnors for its antimitatic effect RecentIy Kim & Kim, reported an exceIIent treatment method. of verrucae with Bleomycin using needle free. They poetulated that the excellent effcts were achievei thraugh infiltration of the ekin, in.cluding the affected epidermis, with Bleomycin which is not possible with other rnethods, It is therefore interesting to know the effects of Dermajet instilled Bleomycin an normal ekin. We selected guinea pigs for thia experirnent. Five albino guixim pigs, weighting about 500 Gm, were ueed. Bleomycin water ohxtion, 0.25mg/ml, 0.06ml for each chet was injected utilizing Dermojet on the back of a guinea pig after clipping. The injected sites and the contralateral sites were tiopsied a,fter vaxying length of time and histologia examinationa were made. The experiment was eoarranged that the biopsies for different experiment aitea celd be done on oxeittirnig. Fix hours after the bleomycin injection, the epidermis becase shrunk and t@4e upper dermie showed aligbt inflammatory infiltration. After 10 hours. and also after 24 houra, a auperficial ulceration and necrosis were noted and the dermal infiltration became progressively severer. After 2 days epithelization, had started and. the necrotic debris began to drop off. After 4 daya the epithelization was camplete. These findings were in sorne part similar to the findings observed in humans by Kirn and Kim in the treatment af verruca but th time sequenc was far faster in guinea pigs.
Animals
;
Biopsy
;
Bleomycin*
;
Epidermis
;
Guinea Pigs*
;
Guinea*
;
Humans
;
Necrosis
;
Needles
;
Skin*
;
Swine
;
Ulcer
;
Warts
;
Water
3.A Prospective Study on Attitude of Professional Student toward Population Related Issues in Korea.
Korean Journal of Preventive Medicine 1976;9(1):11-24
This study was a part of large scale of a prospective study on attitudes of professional students in medicine, nursing and teaching toward population related issues in Korea. The study was first conducted in May 1974 and then in May 1975 for the 1974 class cohot using a questionnaire consisted of attitude scales and other items developed by Lee. The purpose of study was two hold, namely, to determine the difference in students among specializations on one hand and between the first and second years in the 1974 class cohot regarding the subject matter. A one-way analysis of variance was used for attitude scale, and absolute and relative frequency were computed for the analysis of non-attitude scale items by employing Fishers' Ratio and Duncan's multiple range test at 5% level and chi square test at 5% level as significance tests. The hypothesis "students in health profession are more likely to have positive attitudes toward population related issues progressively as class year advances than students in teaching profession" was tested and the following results were obtained: 1) Nursing students were more likely to display favorable attitudes toward family planning than medical or teaching students although the class cohot showed slightly improved attitudes in the second year. 2) Respondents in general perceived national family planning program as a means of population control and this tendency was more true among nursing students as the class year advances than two other professional groups of students. Students in teaching profession appeared to perceive it more as a means to improve individual family welfare while health students were likely to see as to improve maternal and child health. This tendency was progressively improved as the class year advanced. 3) The majority of students regardless of their respective specializations believed that family planning program should be directed toward the improvement of individual family welfare. No progressive changes in the class cohot were observed. 4) About the plan to use contraceptives in future, no significant differences were observed among different specializations nor in different class years. However, the majority was confirmed to have a plan to use contraceptives in future. An increasing proportion of the undecided category was observed, as class year advanced among health students. 5) Students in health profession were found to be more favorable about "more leisure opportunities" as motive for limiting number of children whereas education students indicated the reasons as "facilitate ambitions" and "economic base". The progressive changes toward positive direction in both groups were observed as the class years advanced. 6) Attitudes toward induced abortions of the health student were observed to be positively related to class years while an inverse relationship was found in teaching students who showed much less favor in the subject matter than health students. This phenomenon may be due to the different exposure to learning environments unique to respective specializations. 7) Health students were found to have more favorable attitudes toward population education in general than the teaching students. The teaching students appeared to have changed more to the negative direction when they became the second year while no such development was observed in health students. The teaching students seemed to hold a very conservative position with regard to sex education on schools. 8) About the equality of sexes, the nursing group was found to be most favorable while the reverse was true in the teaching group. 9) About questions related to fertility values-the 10 percent of respondents regardless of specialization indicated that they would maintain their single status in future, however no change was observed in the second year. The desired number of children was found to be two by the majority of students in nursing, medicine and teaching in order of high proportion. No changes in a different class year were observed. The childless marriage was seen by nursing students as a problem more than other students, but a slight change in positive direction was found when the nursing students became the second year. In summing, as data supported in the above, students in health profession demonstrated more favorable attitudes toward population related issues than the teaching students were more conscious about the health aspect of population and family planning program while the teaching students gave more attention the socioeconomic aspect. The sex variable seemed to have operated in the item related to the equality of sexes. In conclusion, as data presented in the above, the hypothesis of this study was accepted except in the few items. It should be noted that the limitation of this study is the short duration of the observation in measuring the possible attitude changes. It should include curriculum analysis for the respective specializations in order to identify the area of curriculum impact on students in future study.
Abortion, Induced
;
Child
;
Child Health
;
Contraceptive Agents
;
Curriculum
;
Surveys and Questionnaires
;
Education
;
Family Planning Services
;
Female
;
Fertility
;
Hand
;
Health Occupations
;
Humans
;
Korea*
;
Learning
;
Leisure Activities
;
Marriage
;
Nursing
;
Population Control
;
Prospective Studies*
;
Surveys and Questionnaires
;
Sex Education
;
Students, Nursing
;
Weights and Measures
4.Bronchogenic Cysts in Adults: CT, MR, and Pathologic Findings.
Kyung Soo LEE ; Joong Mo AHN ; Jeung Sook KIM
Journal of the Korean Radiological Society 1995;32(3):423-428
Bronchogenic cysts can arise either in the mediastinum or in the lung parenchyma. On both CT and T1 -weighted MR images, the cyst contents can show a variable signal characteristics. However, on T2-weighted MR images, the cyst show high signal intensity. Although unusual, the cyst may communicate with the tracheobronchial tree and demonstrate partial or complete air content. With hemorrhage, fluid-fluid levels can also be seen within the cyst. Pathologically, the diagnosis of bronchogenic cyst rests on demonstration of tissues normally found in the tracheobronchial tree within the cyst wall.
Adult*
;
Bronchogenic Cyst*
;
Diagnosis
;
Hemorrhage
;
Humans
;
Lung
;
Mediastinum
5.Cryotherpy of warts with liquid nitrogen.
Kyung Ho SONG ; Kwang Joong KIM ; Chong Ju LEE
Korean Journal of Dermatology 1993;31(4):495-501
BACKGROUND: Despite the widespread use of liquid nitrogen cryoth.rapy on warts, little is known about its therapeutic effects. OBJECTIVE: This study was conducted to evaluate the therapeutic effect of liqiud nitrogen cryotherapy on warts. MEHTODS: One-hundred and fifteen patients with 142 cases of vira warts were studied. The cryosurgery set we used was CS-76 table-top liquid nitrogen spray unit and it was applied directly on the lesion, the freezing front extending 2 to 4mm onto the uninviblvid skin. RESULT: There was an overall cure rate of 69.7% and the averager umber of freezings required for a cure was 2.6 amongst all patients cured by 5 or less freezings at ntervals of 2 or 3 weeks. CONCLUSION: The liquid nitrogen cryotherapy on warts results in a relatively high cure rate with safety, simplicity, rapid healirig, continustion of normal function and a tivities, and restoration of normal appearance.
Cryosurgery
;
Cryotherapy
;
Freezing
;
Humans
;
Nitrogen*
;
Skin
;
Warts*
6.Single Intrauterine Fetal Demise in Twin Gestation.
Joong Sik SHIN ; Eun Kyung LEE ; Jung Bae YOO
Korean Journal of Perinatology 2001;12(2):193-199
No abstract available.
Humans
;
Pregnancy*
;
Twins*
7.Expression of the S Genome Segment of Hantaan 76-118 in E. coli: Evaluation of Antigenicity of the capsid Protein.
Yun Tai LEE ; Bo Kyung YUN ; Jeong Joong YOON ; Kyoung Won YOUN ; Kyung Hee LEE
Journal of Bacteriology and Virology 2001;31(2):187-192
No abstract available.
Capsid Proteins*
;
Capsid*
;
Genome*
8.Traumatic aortic rupture using transesophageal echocardiography: a case.
Joong Hwan OH ; Suk Joong CHOO ; Chong Kook LEE ; Kyung Soo LIM ; Sung Oh HWANG ; Keum Soo PARK
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(3):335-340
No abstract available.
Aortic Rupture*
;
Echocardiography, Transesophageal*
9.A Case of Recurrent Type 1 Herpes Simplex Viral Infection on the Areola after Human Bite.
Hye Min LEE ; Kyung Eun JUNG ; Dae Won KOO ; Joong Sun LEE
Korean Journal of Dermatology 2014;52(5):357-358
No abstract available.
Bites, Human*
;
Herpes Simplex*
;
Humans
;
Simplexvirus
10.Thoracic emphyemas neccessitating surgical management: CT criteria.
Kyung Soo LEE ; Sun Hee HWANG ; Yong Hoon KIM ; Joong Kee NOH ; Byoung Ho LEE
Journal of the Korean Radiological Society 1991;27(4):527-534
No abstract available.