2.Bicervical Bicornuate Uterus with Unilateral Cervical Atresia and Homolateral Renal Agenesis.
Jong Woo HONG ; Seon Kyung LEE
Korean Journal of Obstetrics and Gynecology 1999;42(12):2841-2846
Double uterus with unilateral hematometra and ipsilateral renal agenesis is a rare Mullerian duct malformation. This complex of anomalies is seen in adolescents and young women with progressive dysmenorrhea, abdominal pain, menstrual irregularities and a pelvic mass. Appropriate preoperative diagnosis and treatment will prevent unnecessary procedure and offer relief of symptoms. We report one case of bicornuated uterus with unilateral cervical atresia and homolateral renal agenesis with a brief review of concerned literatures.
Abdominal Pain
;
Adolescent
;
Diagnosis
;
Dysmenorrhea
;
Female
;
Hematometra
;
Humans
;
Unnecessary Procedures
;
Uterus*
3.Role of Renin Angiotensin System in Clitoral avernosum Smooth Muscle.
Seung Choi PARK ; Kyung Woo CHO ; Jong Kwan PARK
Korean Journal of Urology 2000;41(3):387-394
No abstract available.
Muscle, Smooth*
;
Renin*
;
Renin-Angiotensin System*
4.A Case of Athyrotic Cretinism.
Kyung Hae PARK ; Si Man LEE ; Jong Woo SHIN
Journal of the Korean Pediatric Society 1981;24(11):1121-1126
No abstract available.
Congenital Hypothyroidism*
5.Invasive carcinoma of uterine cervix: Clinical studies on 178 cases of radical hysterectomy.
Jong Woo SOHN ; Mi Kyung JANG ; Seon Kyung LEE ; Jung Eun MOK
Korean Journal of Obstetrics and Gynecology 1993;36(11):3734-3749
No abstract available.
Cervix Uteri*
;
Female
;
Hysterectomy*
6.In vitro respones of gynecological cancer cell lines to the GnRH agonist, medroxyprogesterone acetate and tamoxifen.
Jong Woo SOHN ; Jai Kyung PRK ; Seon Kyung LEE ; Seung Bo KIM ; Bo Hoon OH
Korean Journal of Obstetrics and Gynecology 1993;36(9):3436-3443
No abstract available.
Cell Line*
;
Gonadotropin-Releasing Hormone*
;
Medroxyprogesterone Acetate*
;
Medroxyprogesterone*
;
Tamoxifen*
7.Evaluation of Macular Circulation in Patient with Diabetic Maculopathy using Scanning Laser Ophthalmoscope(SLO).
Jong Hyeok LEE ; Sun Wook KIM ; Hyung Woo KWAK
Journal of the Korean Ophthalmological Society 1999;40(6):1574-1581
In the condition of diabetic retinopathy, the vascular changes are localized primarily in the retinal capillaries and are presumed to promote angiogenesis. To investigate the change of retinal blood flow velocities and morphological parameters in diabetic retinopathy, we measured perifoveal capillary blood velocities(v) and the size of foveal avascular zones(FAZ). Thirteen patients with diabetic maculopathy and nine healthy volunteers were included in this study. The scanning laser technique in conjunction with an image analysing system were used to assess the morphological and hemodynamic changes in diabetic retinopathy. Diabetic maculopathy group showed a slower capillary blood velocity than normal group(2.44+/-0.39mm/sec vs2.75+/-0.61 mm/sec, p>0.18). The foveal avascular zone was significantly larger in diabetic maculopathy group than in normal group(313.5+/-64.6micrometervs. 238.9+/-93.8micrometer, p<0.05). This results indicate that the retinal microcirculation is altered in diabetic patients compared with healthy subjects. These alterations may be due to the change of the capillary wall and blood viscosity in diabetic patients. The determination of these parameters can be utilized in monitoring the progress of diabetic maculopathy.
Blood Flow Velocity
;
Blood Viscosity
;
Capillaries
;
Diabetic Retinopathy
;
Healthy Volunteers
;
Hemodynamics
;
Humans
;
Microcirculation
;
Retinaldehyde
8.A Case of Pigmented Dermatofibrosarcoma Protuberans ( Bednar Tumor ) Showing Atrophic Lesions.
Jong Ho LEE ; Doo Yeoul JUNG ; Sook Kyung LEE ; Won Woo LEE
Korean Journal of Dermatology 1998;36(1):139-142
A Bednar tumor is a variant of dermatofibrosarcoma protuberans(DFSP). The clinical and histopathological findings of Bednar tumors are identical to DFSP except for the presence of melanin-containing cells scattered within the lesion, so called pigmented DFSP. The majority of Bednar tumors are seen as DFSP present as multinodular protuberant masses in the skin. They can also present as an atrophic depressed scar-like lesions without any nodularity. We report an uncommon clinical presented case of a Bednar tumor on the back in a 22-year-old female. She presented with an asymptomatic, firm, bluish, chestnut sized, depressed and atrophic lesion on the back which had been present for 6 years. A Histopathological examination revealed massive proliferation of spindle-shaped cells arranged in a tight storiform pattern mixed with scattered pigmented cells. On immunohistochemical staining, the tumor cells were positive for vimentin, a -l-antitrypsin, and CD34, but were negative for cytokeratin, neurofilament, and factor XIIIa. The majority of the tumor cells was negative and the pigment cells were positive for the S-100 protein. The patient was treated by a wide local excision of the lesion. There has been no evidence of recurrence after 20 months post-operative follow up.
Dermatofibrosarcoma*
;
Factor XIIIa
;
Female
;
Follow-Up Studies
;
Humans
;
Keratins
;
Recurrence
;
S100 Proteins
;
Skin
;
Vimentin
;
Young Adult
9.A Study of the Correlation between Expression of c-erbB-2 Oncoprotein and Various Clinicopathological Prognostic Factors in Breast Carcinoma.
Jong Hee NAM ; Kyung Soo KIM ; Chang Soo PARK ; Sang Woo JUHNG
Korean Journal of Pathology 1995;29(2):136-144
Immunohistochemical study for c-erbB-2 oncoprotein was performed on paraffin sections of 76 primary breast carcinomas to determine the relationship between expression of c-erbB-2 and various clinicopathological prognostic indicators, including the expression of epidermal growth factor receptor (EGFR). Positive reaction for c-erbB-2 oncoprotein revealed an intense red granular staining predominantly located at the tumor cell membrane, with some cells exhibiting a weak cytoplasmic staining as well. The epithelial cells of the normal lobule and duct showed a negative reaction. Positive reaction for EGFR revealed a granular staining in the cytoplasm and the cell membrane of the tumor cells. Some tumors showed a positive EGFR staining in the epithelial cells of normal duct and lobule. Twenty six of 76 cases (34.2%) of primary breast carcinomas revealed a positive reaction for c-erbB-2 oncoprotein, and 28 cases (36.8%) were positive for EGFR. Expression of c-erbB-2 oncoprotein and EGFR was evident in 37.7% and 40.6% of 69 classic invasive ductal carcinomas, respectively. None of the other histological types showed a positive reaction. Expression of c-erbB-2 oncoprotein was strongly associated with tumor size(p=0.0015), histologic grade(.p=0.0175), vascular invasion(p=0.0043), and lymph node metastasis(p=0.0024), but not with age at diagnosis(p=0.1836). No significant association was found between expression of c-erbB-2 oncoprotein and EGFR. Co-expression of c-erbB-2 oncoprotein and EGFR was also strongly associated with tumor size (p=0.0029). These results suggest that c-erbB-2 oncoprotein is biologically distinct from EGFR, and may be used as a prognostic indicator of breast carcinoma due to its strong association with various clinicopathological prognostic factors.
10.A Case of Central Diabetes Insipidus Associated with Brachycephaly.
Woo Sik KANG ; Mee Kyung NAMGOONG ; Jae Seung YANG ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1994;37(2):282-287
Brachycephaly is a kind of craniosynostosis. Because of premature closure of the coronal suture, the skull is shorter in the anteroposterior diameter but is widened with a high vault and the occiput and forehead are flattened. Diabetes insipidus had been reported in oxycephaly. We have experienced a case of central diabetes insipidus associated with brachycephaly. A brief review of related literatures is included in this report.
Craniosynostoses*
;
Diabetes Insipidus
;
Diabetes Insipidus, Neurogenic*
;
Forehead
;
Skull
;
Sutures