An autopsy case of a newborn male who died of exsanguination into the subamniotic space of placenta presumably due to the rupture of the umbilical vein, is reported. This fetus, previously uneventful except for hydramnios and partial breech presentation showed obvious signs of fetal distrees during the first stage of labor that lasted for 6 hours to this 25 year old multigravid mother who came to the hospital because of labor pain at 29 weeks of gestation. Immediately after birth the baby was pale and the Apgar score was 1. He died 30 minutes after birth. Postmortem examination confirmed generalized pallor in this 1380 gm baby, with petechial hemorrhage of viscera and subarachnoid hemorrhage. No other findings of the cause of death were found. The placenta showed large ellipsoid subamniotic hematoma containing approximately 76 ml of blood, which is 57% of the total circulation blood volume of the fetus.
Male ; Infant, Newborn ; Humans

Renal angiography is now one of invaluable adjuncts to urologic disease with computed tomography and ultrasonography. Authors observed in 50 cases of renal angiography which performed in the Department of Urology, Kyung Hee University Hospital during the period from September. 1977 to August 1980. In detecting and defining both the presence and extent of renal diseases such as tumor, cyst, injury and vascular disorder, renal angiography is highly reliable and accurate.
Angiography* ; Ultrasonography ; Urologic Diseases ; Urology

OBJECTIVES: Intake of fruits and vegetables has protective effects against stroke attack. This study intended to examine the status of consuming fruits and vegetables and to find out which factors may influence the frequency of consumption of fruits and vegetables in individuals with a history of stroke. METHODS: The data of 208 subjects from 5th (2010, 2011) Korea National Health and Nutrition Examination Survey (KNHNES) who reported a stroke diagnosis was used for analysis. To identify major factors influencing the consumption of fruits and vegetables, a classification-tree analysis was carried out. RESULTS: Among those who reported a stroke diagnosis, the frequencies of consumption of fruits and vegetables were influenced by their age, place of residence (urban or rural), economic status, educational level, occupation, number of family members, frequency of eating out, and having meals (breakfast or lunch) with family members. Two factors from fruits and three factors from vegetables were generated by exploratory factor analyses. Urban residents ate fruits and vegetables more frequently in all factors than rural residents. Eating frequencies of 'seasonal fruits (orange, apple, strawberry, melon, pear and watermelon)', 'easily-accessible fruits (persimmon, tangerine, grape, peach, banana)', and 'Western-style vegetables (cabbage, mushroom, carrot, tomato, spinach)' were influenced by the socioeconomic status. Eating frequencies of 'Korean-style vegetables (bean sprout, radish leaves, pumpkin/squash, sea weed)', 'preserved vegetables (Korean cabbage, radish, laver, cucumber)' were influenced by having breakfast with amily members. CONCLUSIONS: The results of this study suggested that by eating more fruits and vegetables, more preventive effects against secondary stroke attack are expected in stroke patients who live in the rural areas and who do not eat breakfast with family members. In addition, more outreach and education programs are needed for them.
Agaricales ; Brassica ; Breakfast ; Cucurbitaceae ; Daucus carota ; Diagnosis ; Eating ; Education ; Educational Status ; Fragaria ; Fruit* ; Humans ; Korea ; Lycopersicon esculentum ; Meals ; Nutrition Surveys* ; Occupations ; Prunus persica ; Pyrus ; Raphanus ; Social Class ; Stroke* ; Vegetables* ; Vitis

Authors reviewed 110 cases of retrograde pyelography which performed in the Dept. of Urology, Kyung Hee University Hospital during the period from January 1977 to December 1980. And the results were as follows. 1. Indication was 34 cases (31%) of nonvisualizing kidney, 31 cases (28%) of obstructive lesion, 21 cases (19%), of inadequate filling in pelviocalyceal system, 7 cases (6.5%) of impaired renal function. 6 cases (5.5%) of upper tract abnormality, l cases (0.9%) of allergy to contrast media and other 10 cases. 2. On the nonvisualizing kidney, hydronephrosis (23.5%) was most common and normal (20.5%), ureter stone (20.5%) in order. 3. For assessment of obstructive lesion, UPJ stricture (39%) was most common and ureter stone (32%), normal (16%), ureter tumor, UVJ stricture in order. 4. Inadequate filling on excretory urogram revealed normal (24%), renal tumor (19%), renal tuberculosis (9.5%) and chronic pyelonephritis scar (9.5%) etc. 5. The patients who had poor renal function or poor general condition and upper tract abnormality were well defined with retrograde pyelography and available for diagnosis and treatment. 6. Complication were seen in 2 cases (1.8%). One was acute pyelonephritis and the other was pyonephrosis.
Cicatrix ; Constriction, Pathologic ; Contrast Media ; Diagnosis ; Humans ; Hydronephrosis ; Hypersensitivity ; Kidney ; Pyelonephritis ; Pyonephrosis ; Tuberculosis, Renal ; Ureter ; Urography* ; Urology

No abstract available.
Stevens-Johnson Syndrome*

No abstract available.
Arthroplasty, Replacement, Hip* ; Ceramics* ; Hip*

No abstract available.
Humans ; Twins*

No abstract available.
Protein-Losing Enteropathies

BACKGROUND: The treatment goal for patients with chronic hepatitis B infection is to prevent progression of the disease to cirrhosis and hepatocellular carcinoma. Current therapies include standard and pegylated interferon-alfa and nucleoside/nucleotide analogues: lamivudine, adefovir, entecavir, telbivudine, clevudine, and tenofovir. This study aims to analyze changes in the prescribing patterns of chronic hepatitis B (CHB) medications in South Korea between 2013 and 2014. METHODS: A cross-sectional study was conducted using National Patients Sample data compiled by the Health Insurance Review and Assessment Service from 2013 and 2014. Patients with CHB were identified with Korean Standard Classification of Diseases code-6 (B18.0 and B18.1) and those who were maintaining active prescriptions with CHB medications covering the index date (December 1(st), each year) were included. The utilization of antiviral therapy was investigated during 2013 and 2014. RESULTS: A total of 4,204 and 4,552 patients in 2013 and 2014 respectively, were included in the analysis. The proportion of male patients was two of third and the patients 41-60 years old accounted for 60% of all analyzed patients. The most utilized drug was entecavir (55.1% in 2013 and 44.8% in 2014) and the second most utilized drug was tenofovir in both years (18.8% in 2013 and 29.0% in 2014). The percentage of combination therapy was 13.6% and 13.1% in 2013 and 2014, respectively. The proportion of tenofovir prescriptions was increased in 2014 compared with 2013. CONCLUSION: With the development of new drugs and the changes in clinical practice guidelines, the prescription pattern of the antiviral agents for patients with CHB has changed. The rate of utilization of tenofovir has increased.
Antiviral Agents ; Carcinoma, Hepatocellular ; Classification ; Cross-Sectional Studies ; Drug Utilization* ; Fibrosis ; Hepatitis B, Chronic* ; Hepatitis, Chronic* ; Humans ; Insurance, Health ; Korea ; Lamivudine ; Male ; Prescriptions ; Tenofovir

PURPOSE: It has been recognized that interaction of the Fas : Fas ligand plays an important role in radiation-induced apoptosis. The purpose of this study was to investigate the role of Fas mutation in radiation-induced apoptosis in vivo. MATERIALS AND METHODS: Mice with mutations in Fas, MRL/Mpj-Fas(lpr), and its normal control, MRL/Mpj, were used in this study. Eight-week old male mice were given whole body radiation. After irradiation, the mice were killed and their spleens were collected at different time intervals. Tissue samples were stained with hematoxylin-eosin and the numbers of apoptotic cells were scored. Regulating molecules of apoptosis including p53, Bcl-2, Bax, Bcl-XL, and Bcl-XS were also analyzed by Western blotting. RESULTS: At 25 Gy irradiation, the level of apoptosis reached the peak value at 8 hr after radiation and recovered to the normal value at 24 hr after radiation in MRL/Mpj mice. In contrast, the peak apoptosis level appeared at 4 hr after radiation in MRL/Mpj-Fas(lpr) mice. At 8 hr after radiation, the levels of apoptosis in MRL/Mpj mice and MRL/Mpj-Fas(lpr) mice were 52.3+/-7.8% and 8.0+/-8.6%, respectively (p<0.05). The expression of apoptosis regulating molecules, p53, Bcl-XL and Bcl-XS, increased in MRL/Mpj mice in response to radiation; p53 with a peak level of 3-fold at 8 h, Bcl-XL with a peak level of 3.3-fold at 12 h, and Bcl-XS with a peak level of 3-fold at 12 h after 25 Gy radiation. Bcl-2 and Bax did not show significant change in MRL/Mpj mice. However in MRL/Mpj-Fas(lpr) mice, the expression levels of p53, Bcl-2, Bax, Bcl-XL and Bcl-XS showed no significant change. CONCLUSION: The level of radiation-induced apoptosis was lower in Fas mutated mice, lpr, than in control mice. This seemed to be related to the lack of radiation-induced p53 activation in the lpr mice. This result suggests that Fas plays an important role in radiation-induced apoptosis in vivo.
Animals ; Apoptosis* ; Blotting, Western ; Fas Ligand Protein ; Humans ; Male ; Mice ; Radiation Dosage ; Reference Values ; Spleen ; Whole-Body Irradiation