1.Molecular Neuroendocrine Regulation of GnRH and Its Recceptor.
Journal of Korean Society of Endocrinology 1997;12(4):493-503
No abstract available.
Gonadotropin-Releasing Hormone*
2.Two Cases of Congenital Chylothorax Diagnosed by Prenatal Ultrasonography.
Kyung Hyun CHUNG ; Wan CHO ; Man Yong HAN ; Bo Kyung KIM ; Kyu Hyung LEE
Korean Journal of Perinatology 1999;10(4):512-517
Congenital chylothorax is a rare disorder and can be diagnosed by prenatal ultrasonography recently. Most cases of congenital chylothorax were characterized by different clinical courses of respiratory distress. We describe two female cases with congenital chylothorax observed by ultra- sonography prenatally. In the first case, left-sided pleural effusion was noted by prenatal ultrasonography taken at 34 weeks of gestation, and then pleural fluid was extracted by intrauterine thoracentesis under sonography guidance. After birth, this patient was managed by TPN(total parentral nutrition) and intermittent thoracentesis without surgical treatment. But, pleural fluid was accumulated recurrently and respiratory distress was aggravated. At 15th hospital day, shock state was developed and patient died. In the second case, bilateral pleural effusion and ascites were noted by prenatal ultrasonography, and then patient was delivered immediately without intrauterine thoracentesis. After birth, the second case received conservative therapy including mechanical ventilation, TPN, intermittent thoracentesis and paracentesis. The patient was discharged with complete regression of chylothorax. We report the two cases with brief review of related literatures.
Ascites
;
Chylothorax*
;
Female
;
Humans
;
Paracentesis
;
Parturition
;
Pleural Effusion
;
Pregnancy
;
Respiration, Artificial
;
Shock
;
Ultrasonography, Prenatal*
3.A Case of Congenital Asplenia Syndrome.
Hyung Sook KIM ; Jin Soo CHO ; Sung Kee JIM ; Doo Sung MOON ; kyung Sook CHO ; Jong Dae CHO
Journal of the Korean Pediatric Society 1987;30(2):218-222
No abstract available.
Heterotaxy Syndrome*
4.A clinical analysis of respiratory failure in patients with acute organophosphorus poisoning.
Hyung Kug RYU ; Hyung Won HAN ; Hee Young CHO ; In Hwan KIM ; Il Se LEE ; Kyung Min LEE
Korean Journal of Medicine 1993;45(4):507-515
No abstract available.
Humans
;
Organophosphate Poisoning*
;
Respiratory Insufficiency*
5.Clinical usefulness of rapid antigen test to detect respiratory syncytial virus infection.
Hyung Su KIM ; Hee La KIM ; Ki Hyung PARK ; Kyung Soon CHO
Korean Journal of Pediatrics 2008;51(10):1071-1076
PURPOSE: Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory infections in infants and young children. Early detection allows quarantining of infected inpatients to prevent nosocomial transmission and to choose a treatment. To achieve rapid reporting, to facilitate prompt antiviral therapy, and to avoid unnecessary use of antibiotics, an easy, rapid diagnostic method for RSV is needed. We evaluated a lateral flow immunochromatography (RSV Respi-Strip test) and EIA (Enzyme immuno assay) compared to RT-PCR. METHODS: From April 2007 to March 2008, 112 consecutive respiratory specimens (nasopharyngeal aspirates, throat swabs, tracheal aspirates, sputum) from patients who were suffering from the clinical signs and symptoms of respiratory tract infection were enrolled in Busan. A total of 112 patients were tested with RSV Respi-Strip (Corio-BioConcept, Belgium), EIA, and RT-PCR at the same time. RESULTS: Of the 112 specimens tested, the number of children who showed positive results at RT-PCR and Respi-Strip were 45 and 42, respectively. The Respi-Strip rapid antigen test had a sensitivity of 88% and a specificity of 94%. The positive and negative predictive values were 90% and 92%, respectively. The agreement was 83%. CONCLUSION: In our study, the rapid antigen test had as much sensitivity as any method for detection of RSV. The test has many advantages such as easy performance, simple interpretation, and rapid results. If the rapid antigen test is widely applied in the clinical setting, the may be useful for diagnostic and epidemiological studies of RSV infection.
Anti-Bacterial Agents
;
Child
;
Humans
;
Immunochromatography
;
Infant
;
Inpatients
;
Pharynx
;
Respiratory Syncytial Viruses
;
Respiratory Tract Infections
;
Sensitivity and Specificity
;
Stress, Psychological
6.Detection of BLV Proviral DNA in Korean Native Goats Experimentally Infected with Bovine Leukemia Virus by Polymerase Chain Reaction.
Moo Hyung JUN ; Kyung Soo CHANG ; Young Sung CHO ; Jong Hyeon PARK ; Soo Hwan AN
Journal of the Korean Society of Virology 1997;27(2):217-226
PCR implication using the primers for gag, pol and rev genes in BLV (bovine leukemia virus) proviral DNA and syncytium assay were carried out for the Korean native goats experimentally infected with bovine leukemia virus to investigate pathogenesis of BLV in the goats, and to establish a model animal for BLV infection. The oligonucleotide primers used in PCR revealed very high specificity, The minimal amount of FLK-BLV cellular chromosomal DNA to detect the integrated BLV proviral DNA was 10 ng. The peripheral blood lymphocytes from the goat infected with BLV were examined at regular intervals by PCR amplification and syncytium assay. Pol or gag genes were detected in none of three infected goats at the 1st week post-infection (p.i.). At the 4th week p.i., one of three goats showed the amplified gag gene. Thereafter detection rates for the genes were increased, indicating that the BLV proviral genes were integrated in all of the lymphocytes from three goats, at the 16th weeks p.i., when it was evident in syncytium assay that the lymphocytes from all of three goats were infested with infective BLV. Investigating the tissues from the necropsied goats at the 8th month p.i., the amplified BLV proviral genes and infective BLV were detected in all of the peripheral lymphocytes from three infected-goats. Among various tissues examined, the amplified BLV proviral genes were observed in spleen and superficial cervical, mandibular and retropharyngeal lymph nodes, and the infective BLV, in superficial cervical and mandibular lymph nodes. It was assumed that the Korean native goat was quite susceptible to BLV infection, indicating that the goat could be a good model animal for BLV.
Animals
;
Cattle
;
Deltaretrovirus Infections
;
DNA Primers
;
DNA*
;
Enzootic Bovine Leukosis*
;
Genes, gag
;
Genes, rev
;
Giant Cells
;
Goats*
;
Leukemia
;
Leukemia Virus, Bovine*
;
Lymph Nodes
;
Lymphocytes
;
Polymerase Chain Reaction*
;
Sensitivity and Specificity
;
Spleen
7.Location and cloning of the polyhedrin gene of hyphantria cunea nuclear polyhedrosis virus.
Hyung Hoan LEE ; Mi Kyung LEE ; Il Hwan CHO ; Kwan Hee YOO
Journal of the Korean Society of Virology 1991;21(1):25-34
No abstract available.
Clone Cells*
;
Cloning, Organism*
;
Nucleopolyhedrovirus*
8.Infectivity of bovine leukemia virus to Korean native goats I. antibody responses and syncytium assay for Korean native goats experimentally infected with bovine leukemia virus.
Young Sung CHO ; Moo Hyung JUN ; Kyung Soo CHANG ; Young Do CHOI
Journal of the Korean Society of Virology 1993;23(2):153-163
No abstract available.
Animals
;
Antibody Formation*
;
Cattle
;
Enzootic Bovine Leukosis*
;
Giant Cells*
;
Goats*
;
Leukemia Virus, Bovine*
9.Two Case of Sudoriparous Angioma.
Guk Joo CHOI ; Kyung Hwan CHO ; Dong HOUH ; Hyung Ok KIM ; Chung Won KIM
Korean Journal of Dermatology 1982;20(6):957-964
Sudoriparous angioma is an unusual form of angioma with pain and hyperhidrosis. We present two cases of typical sudoriparous angioma. Case 1: 9-year-old female showed 0. 8 to 2. 0cm multiple dark brownish tender palpable hypertrichotic masses on the right lower leg after birth. Muscular atrophy and flexion contracture was also developed on the right lower leg for 2 years. Case 2: 4-year-old rnale showed 3 * 3cm tender elevated mass on the left shin after birth. Marked hyperhidrosis was developed when even slight pressure applied on the lesion in these cases. On histologic examination, these two cases showed proliferation of varible sized blood veasels hyperplasia and dilated hyperplastic eccrine glandular and ectopic adipose tissue on the mid and deep dermis. Muscular biopsy from case 1 showed fibrotic and degenerative change. Electromicroscopic examination done from case 1. The secretory epithelial cell of eccrine gland showed cytoplastic degradation and slight dilated intercellular canaliculi (Fig. 11). The lumen of subepithelial capillaries were dilated and some of endothelial cells showed degenerative changes evidenced by RER dilation, mitochondrial swelling and detachment from underlying tissue(Fig. l2). The cutaneous nerve showed many non-myelinated axons enclosed in cytoplasm of Schwann cells.
Adipose Tissue
;
Axons
;
Biopsy
;
Capillaries
;
Child
;
Child, Preschool
;
Contracture
;
Cytoplasm
;
Dermis
;
Eccrine Glands
;
Endothelial Cells
;
Epithelial Cells
;
Female
;
Hemangioma*
;
Humans
;
Hyperhidrosis
;
Hyperplasia
;
Leg
;
Mitochondrial Swelling
;
Muscular Atrophy
;
Parturition
;
Schwann Cells
10.A case of intracranial arterial thrombosis in nephrotic syndrome.
Moon Gyoo KANG ; Hee Young CHO ; Hyung Kug RYU ; Kyung Min LEE ; Hyo Keun BAE
Korean Journal of Nephrology 1991;10(2):224-227
No abstract available.
Nephrotic Syndrome*
;
Thrombosis*