1.Effect of Interleukin-2 on the Surgically Induced Enndometriosis in Rat.
Kyung Soo HAHM ; Kyung Soo NAM ; Dong Mok LEE ; Hai Bum SONG ; Dong Hoon KIM ; Yun Hee SHON
Korean Journal of Immunology 1999;21(2):153-157
It has been shown that wornen with endometriosis have several immunological defects. The effect of interleukin-2 (IL-2) for the treatment of induced endometriosis in rat was studied. The results obtained are as followings: proliferation of epithelium is increased, and the inner surface is undulated with 1.5 nM IL-2. In 7.5 nM IL-2, the epithelial cells are changed to columar ones, and secretory hobs are observed at the apex of individual cell. Secretory activity of epithelium is increased with 0.5 nM IL-2, and apoptosis of the epithelial cell is observed in 15 nM IL-2. The levels of progesterone and estradiol in sera of rat were increased after treatment with IL-2 and were highest in the concentration of 1.5 nM IL-2. The results of this study can be a guide in the development of new therapeutic approaches for the treatment of endometriosis.
Animals
;
Apoptosis
;
Endometriosis
;
Epithelial Cells
;
Epithelium
;
Estradiol
;
Female
;
Interleukin-2*
;
Progesterone
;
Rats*
2.Correlation of Tc-diphosphonate bone scintigraphic findings and histologic grade in prostatic adenocinoma.
So Jin LEE ; Chang Yoon PARK ; Jong Doo LEE ; Jin Suck SUH ; Jin Kyung HAHM ; Nam Hoon CHO
Journal of the Korean Radiological Society 1993;29(6):1356-1360
Prostatic adenocarcinoma is a common genitourinary malignancy which frequently is assiciated with bony metastasis at initial diagnosis. The detection of bony metastasis is important because it often alters the therapeutic strategy. The radionuclide one scintigraphy is known to be the most sensitive diagnostic method in detecting bony metastasis from prostatic adenocarcinoma. In the histologic grading of prostatic adenocarcinoma, the Gleason's grading system is the most widely employed one which is based on the degree of glandular differentiation and the growth patterns of tumor in relation to the prostatic stroma. The purpose of this study is to know the correlation of Gleason's grade and bone scintigraphic findings in prostatic carcinoma. We analyzed 99mTc-diphosphonate bone scintigraphies of 19 cases with prostatic adenocarcinoma confirmed by transurethral prostatic biopsy. Ten of the 19 cases showed asymmetrical multiple radioisotope uptake suggesting bony metastases and their Gleason's grade were 4 or 5 in seven cases. The remaining three cases were Gleason's grade 2 or 3. Another nine cases showed symmetrical radioisotope uptake with normal renal imaging suggesting no bony metastases and their Gleason's grade were 1,2 or 3 in seven cases. The remaining two cases of these nine cases were Gleason's grade 4 and 5. As the results, there was a correlation between the Gleason's grade and bone scintigraphic findings. The asymmetrical multiple skeletal uptake of radioisotope may suggest that the Gleason's grade is likely to be higher.
Adenocarcinoma
;
Biopsy
;
Diagnosis
;
Methods
;
Neoplasm Metastasis
;
Radionuclide Imaging
3.Sudden persistent fetal bradycardia after spinal analgesia for labor pain.
Yang Hoon CHUNG ; Won Ho KIM ; Eun Kyung LEE ; Tae Soo HAHM
Korean Journal of Anesthesiology 2013;65(6 Suppl):S99-S100
No abstract available.
Analgesia*
;
Bradycardia*
;
Female
;
Labor Pain*
;
Pregnancy
4.Sudden persistent fetal bradycardia after spinal analgesia for labor pain.
Yang Hoon CHUNG ; Won Ho KIM ; Eun Kyung LEE ; Tae Soo HAHM
Korean Journal of Anesthesiology 2013;65(6 Suppl):S99-S100
No abstract available.
Analgesia*
;
Bradycardia*
;
Female
;
Labor Pain*
;
Pregnancy
5.Hypotension in patients administered indigo carmine containing impurities: A case report.
Sung Hoon KIM ; Eun Ha SUK ; So Hyun KIL ; Kyung Don HAHM ; Jai Hyun HWANG
Korean Journal of Anesthesiology 2011;61(5):435-438
Indigo carmine has been used for eight decades with few adverse effects. Several of our patients, however, experienced severe hypotensive episodes after indigo carmine administration within a period of one month. Analysis of the raw materials used to formulate the preparation of indigo carmine we used showed that they contained impurities. Following recall of these impure materials, none of our patients experienced further hypotensive episodes.
Humans
;
Hypotension
;
Indigo Carmine
;
Indoles
6.A Case of Henoch - Schoenlein Purpura Involving upper GI Tract.
Ji Hoon KIM ; Ock Chan LEE ; Kyoung Won KAHNG ; Jong Chul RHEE ; Joon Soo HAHM ; Min Ho LEE ; Dong Ho LEE ; Choon Suhk KEE ; Kyung Nam PARK ; Moon Hyang PARK
Korean Journal of Gastrointestinal Endoscopy 1992;12(2):231-235
Henoch-Schonlein purpura(anaphylactoid purpura) is a necrotizing vasculitis of small vessels in which systemic manifestation include palpable purpura on the lower extremities and buttocks due to leukocytoclastic vasculitis of dermal vessels; arthralgia of large joints, usually the knees and ankles; gastronitestinal involvement with colic and bleeding; and renal ievolvement, usually with a focal necrotizing glomerulonephritis. Gastrointestinal involvement occurs in about two thirds of all pediatric cases and in about,one third of adult cases, Any bowel segment may be involved, but the jejunum and ileum are most frequently affected. With a brief review of the literature, we report a case of H-S purpura involving stomach and duodenum.
Adult
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Ankle
;
Arthralgia
;
Buttocks
;
Colic
;
Duodenum
;
Glomerulonephritis
;
Hemorrhage
;
Humans
;
Ileum
;
Jejunum
;
Joints
;
Knee
;
Lower Extremity
;
Purpura*
;
Stomach
;
Upper Gastrointestinal Tract*
;
Vasculitis
7.Spontaneous Renal Artery Dissection Complicated by Renal Infarction.
Young Il HAHM ; Young Jin SIM ; Kyung Seo PARK ; Yong Seol PARK ; Kwan Joong JOO ; Chil Hoon KWON ; Heung Jae PARK
Korean Journal of Urology 2008;49(4):376-378
A previously healthy 44-year-old woman, with no notable medical history developed left flank pain. To rule out left renal infarction, enhanced abdominal computed tomography(CT) was done and a wedge shaped hypointense lesion was identified in the left posteromedial aspect of the interpolar region. Renal angiography revealed an isolated renal artery dissection that was causing renal infarction due to narrowing of the main stem of the left renal artery. The patient experienced pain with severe uncontrolled hypertension. The patient was successfully treated by percutaneous angioplasty and renal artery stenting.
Adult
;
Angiography
;
Angioplasty
;
Female
;
Flank Pain
;
Humans
;
Hypertension
;
Infarction
;
Renal Artery
8.Primary Aldosteronism Presenting as Hypokalemia and Rhabdomyolysis.
Kee Hong PARK ; Soo Kyung KIM ; Eun Bin CHO ; Heejeong JEONG ; Nack Cheon CHOI ; Oh Young KWON ; Byeong Hoon LIM ; Jong Ryeal HAHM ; Ki Jong PARK
Korean Journal of Clinical Neurophysiology 2016;18(1):21-24
Primary aldosteronism is one of the most common cause of secondary hypertension and can be accompanied with hypokalemia. Rhabdomyolysis with hypokalemia in primary aldosteronism has been rarely reported. We describe a patient of primary aldosteronism who presented with limb-girdle type weakness.
Humans
;
Hyperaldosteronism*
;
Hypertension
;
Hypokalemia*
;
Rhabdomyolysis*
9.Colonic Transit Time in Patient with Liver Cirrhosis.
Young Hoon KIM ; Sung Gon SIM ; Kyung Ran CHO ; Jin Bae KIM ; Oh Young LEE ; Ho Soon CHOI ; Joon Soo HAHM ; Min Ho LEE
The Korean Journal of Gastroenterology 2003;42(5):394-399
BACKGROUND/AIMS: The colonic transit time in patients with liver cirrhosis has not been studied extensively in South Korea. Thus, the authors investigated the differences of colonic transit time between cirrhotic patients and normal controls with attention to factors that affect this change. METHODS: Fifteen cirrhotic patients and 15 controls were included in this study. To exclude any organic diseases, colonoscopy was preceded. The colonic transit time was measured by taking plain abdominal films on the 4th and 7th days after ingestion of radiographic non-absorbable colon markers for 3 days. RESULTS: The colonic transit time was 10.7 +/- 2.6 hours and 24.0 +/- 4.1 hours for cirrhotic patients and controls, respectively, indicating that the transit time in cirrhotic patients is much faster (p<0.05). The transit time for each segment of the colon was also measured. For the ascending colon, average transit time of the cirrhotic patients and controls were 5.60 +/- 1.93 and 6.88 +/- 1.77 hours respectively. For the descending colon, those were 2.80 +/- 1.04 and 10.80 +/- 2.59 hours (p<0.05), while those in the rectosigimoid portion were 2.32 +/- 0.81 and 4.96 +/- 1.19 hours, respectively. These results indicated that a significant difference is present in the descending colon. Additionally, the transit time is correlated with age and albumin level (B=0.760, p<0.05 and B=7.498, p<0.01, respectively). CONCLUSIONS: The colonic transit time of cirrhotic patients is faster than that of control, especially in the descending colon.
Colon/*physiopathology
;
Female
;
*Gastrointestinal Transit
;
Humans
;
Liver Cirrhosis/*physiopathology
;
Male
;
Middle Aged
10.Posterior Mediastinal Panniculitis: A Case Report.
Kyung Joo LEE ; Seok Chol JEON ; Yo Won CHOI ; Heung Seok SEO ; Chang Kok HAHM ; Choong Ki PARK ; Jung Dal LEE ; Hoon Ki PARK
Journal of the Korean Radiological Society 1999;41(3):511-513
Panniculitis is an inflammatory reaction of the subcutaneous fat. Erythema nodosum is its most common form and mesenteric panniculitis is well known. We describe a case of posterior mediastinal panniculitis confirmed by gun biopsy and describe the CT and pathologic findings. CT showed a paraspinal mass containing a small amount of fat in the posterior mediastinum.
Biopsy
;
Erythema Nodosum
;
Mediastinum
;
Panniculitis*
;
Panniculitis, Peritoneal
;
Subcutaneous Fat